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Material Safety Data Sheet for Zinc Citrate

Identification

Product Name: Zinc Citrate
Chemical Formula: C6H6O7Zn
Synonyms: Trizinc dicitrate, Zinc(II) citrate
CAS Number: 546-46-3
Recommended Use: Used in dental care products, food supplements, pharmaceuticals, and agricultural applications
Manufacturer Information: Provided by manufacturer or distributor upon request
Emergency Contact: Refer to local emergency response systems for chemical incidents
Product Group: Inorganic zinc salts

Hazard Identification

GHS Classification: Eye Irritation (Category 2), Skin Irritation (Category 2)
Hazard Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; may cause respiratory irritation
Precautionary Statements: Avoid breathing dust; wash thoroughly after handling; use in well-ventilated areas; wear protective gloves and eye protection
Other Hazards: May be harmful if swallowed in large quantities; dust can cause mechanical irritation to respiratory tract

Composition / Information on Ingredients

Chemical Name: Zinc Citrate
CAS Number: 546-46-3
Concentration: 99% or higher
Impurities: Trace metals (lead, cadmium, arsenic) kept below regulatory limits
EC Number: 208-912-2

First Aid Measures

Inhalation: Move exposed person to fresh air; seek medical attention if symptoms persist (coughing, shortness of breath, or irritation)
Skin Contact: Remove contaminated clothing; wash skin with soap and water; seek medical attention if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing; get medical help if irritation remains
Ingestion: Rinse mouth; do not induce vomiting; seek medical advice if symptoms such as abdominal discomfort or nausea appear

Fire-Fighting Measures

Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Hazards from Combustion: May emit toxic fumes of zinc oxides and carbon oxides on thermal decomposition
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Additional Advice: Prevent run-off from entering drains; cool nearby containers with water mist if safe to do so

Accidental Release Measures

Personal Precautions: Use personal protective equipment such as gloves, goggles, and mask; avoid dust formation
Environmental Precautions: Prevent further spillage; block entry into waterways, soil, or drains
Clean-up Procedures: Sweep or vacuum up material in a manner that minimizes dust generation; place in a suitable container for proper disposal; ventilate the area; wash spill site after cleanup

Handling and Storage

Safe Handling: Avoid contact with skin, eyes, and clothing; do not breathe dust; use in well-ventilated areas; hygiene precautions recommended
Storage Requirements: Keep container tightly closed; store in a dry, cool, and well-ventilated space; avoid incompatible substances such as strong acids and bases
Packaging Materials: Use corrosion-resistant, tightly sealed containers to avoid moisture ingress
Special Precautions: Avoid generating airborne dust; keep away from food, beverages, and animal feed

Exposure Controls and Personal Protection

Occupational Exposure Limits: ACGIH TLV for zinc compounds (as Zn, inhalable particulate): 2 mg/m³
Engineering Controls: Local exhaust ventilation; process enclosure; dust collection systems
Personal Protective Equipment: Safety goggles; chemical-resistant gloves; long-sleeved clothing; particulate respirator if dust is generated
General Measures: Wash hands after handling; avoid eating, drinking, or smoking in working area; remove contaminated clothing and wash before reuse
Environmental Exposure Control: Follow all applicable regulations to prevent accidental releases into the environment

Physical and Chemical Properties

Appearance: White to off-white odorless powder
Molecular Weight: 574.29 g/mol
Solubility: Slightly soluble in water; insoluble in ethanol
Melting Point: Decomposes above 100 °C
pH (1% solution): 5-7
Boiling Point: Not applicable
Vapor Density: Not applicable
Specific Gravity: Around 2.3-2.5 at 20 °C
Flash Point: Not relevant (non-flammable)
Auto-Ignition Temperature: Not relevant
Oxidizing Properties: Not classified as an oxidizer

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and recommended storage conditions
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Decomposition Products: Thermal decomposition can form zinc oxide and hazardous carbon oxides
Hazardous Polymerization: Does not occur
Conditions to Avoid: Excessive heat, moisture, contact with incompatible substances

Toxicological Information

Acute Toxicity: Oral LD50 (rat): >5,000 mg/kg; low acute toxicity
Skin Corrosion/Irritation: May cause mild to moderate irritation
Serious Eye Damage/Irritation: Possible significant irritation on contact
Respiratory Sensitization: Not reported
Carcinogenicity: Not classified as a carcinogen by NTP, IARC, or OSHA
Chronic Toxicity: Repeated or prolonged exposure can impact kidney and digestive tract functions in rare cases
Mutagenicity/Teratogenicity: No strong evidence from current studies
Other Information: Ingestion of excessive amounts may lead to zinc toxicity, including symptoms such as nausea, vomiting, diarrhea, and cramps

Ecological Information

Ecotoxicity: Toxic to aquatic organisms in elevated concentrations; may cause adverse effects in freshwater and marine environments
Persistence and Degradability: Not rapidly biodegradable; remains in the environment as an inorganic salt
Bioaccumulation Potential: Low for mammals; moderate for some aquatic species
Mobility in Soil: Limited mobility; strongly binds to soil particles
Other Adverse Effects: Do not release product or solutions containing product to natural water bodies without regulatory guidance

Disposal Considerations

Waste Treatment Methods: Dispose of contents and container in accordance with local, regional, national, and international regulations
Product Disposal: Avoid discharge into sewage systems and natural waterways; use authorized chemical waste facilities
Contaminated Packaging: Containers should be emptied and cleaned before recycling or disposal
Special Precautions: Prevent accidental spillages from entering drains; consult relevant environmental authorities for guidance

Transport Information

UN Number: Not regulated for transport
Transport Hazard Class: Not classified as a hazardous material
Packing Group: Not applicable
Special Precautions for Users: Protect from physical damage and moisture during transport
Environmental Hazards: Avoid accidental release into environment during loading/unloading
Regulatory Information: Ensure compliance with country-specific transport regulations

Regulatory Information

EPA Status: Not listed as hazardous under US EPA; comply with Clean Water Act and local environmental requirements
REACH Registration: Compliant as per European chemicals regulations; included in inventory
OSHA: Not considered hazardous per OSHA Hazard Communication Standard (29 CFR 1910.1200)
TSCA Inventory: Listed
Other Regulations: Adhere to workplace safety, environmental, and transport laws for local jurisdictions; Safety data must be communicated to workers as required by law