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Product Name: Zeaxanthin
Chemical Name: Zeaxanthin
Synonyms: All-trans-zeaxanthin
CAS No.: 144-68-3
Molecular Formula: C40H56O2
Recommended Use: Dietary supplement, food coloring, research applications
Supplier Details: Full address, emergency contact number, and business telephone number required by compliance standards
Emergency Contact: Local poison control, CHEMTREC, or supplier emergency line essential for prompt response.
Classification: Zeaxanthin may be classified as non-hazardous under GHS; not listed as carcinogenic or toxic for reproduction
Health Hazards: Eye or skin irritation possible through direct exposure; ingestion in large quantities can affect digestive system
Environmental Hazards: Data suggests low risk of aquatic toxicity, but spill response should minimize environmental exposure
Label Elements: No pictograms or signal words commonly required; precautionary statements may advise basic hygiene and handling
Routes of Exposure: Inhalation of dry powder, ingestion, contact with skin or eyes considered
Target Organs: None known from published research at food or supplement levels
Chronic Effects: Long-term studies in typical usage contexts show no clear adverse effects, but overdose risks for supplements remain
Chemical Identity: Zeaxanthin
CAS Number: 144-68-3
Percentage: Pure zeaxanthin powder usually over 98%
Impurities: Trace carotenoids, moisture less than 1%, solvents below detection limits when manufactured for dietary use
Other Ingredients: None in technical grade samples; finished food or supplement products may include stabilizers or carriers, which must be checked on finished formulation MSDS
Eye Contact: Rinse immediately with plenty of water, keep eyelids open, flush for several minutes
Skin Contact: Wash with soap and water; remove contaminated clothing
Inhalation: Move to fresh air and monitor for symptoms such as cough or shortness of breath; seek medical attention if adverse effects persist
Ingestion: Rinse mouth, drink water, do not induce vomiting, consult physician for large exposure
Symptoms: May include mild irritation, allergic response uncommon; ingestion in excessive amounts could cause stomach upset or nausea
Suitable Extinguishing Media: Use dry chemical, carbon dioxide, foam, or water spray
Special Hazards: Fine dust in air can form explosive mixture; standard risk where organic powders handled
Protective Equipment/Precautions: Firefighters need self-contained breathing apparatus and protective clothing
Hazardous Combustion Products: May emit carbon monoxide, carbon dioxide under fire conditions
Explosion Limits: Lower explosive dust concentrations not established, but dust suppression important for safety during handling
Personal Protection: Use gloves, goggles, mask to prevent skin, eye, respiratory exposure
Environmental Protection: Prevent entry into waterways and drains; recover spills promptly
Methods for Clean-Up: Use wet methods or HEPA-filtered vacuum to minimize dust; sweep up spilled powder carefully and place in waste container
Decontamination: Clean surfaces with water and detergent; avoid raising dust during clean-up cycle
Handling: Avoid dust generation, use with local exhaust ventilation, minimize direct contact
Personal Hygiene: Wash hands thoroughly after use, remove contaminated clothing before leaving work area
Storage: Store in airtight containers, keep in cool, dry, well-ventilated place; protect from light and heat to preserve stability
Incompatibilities: Strong oxidizers, acids, and bases break down the compound
Special Precautions: Avoid eating, drinking, or smoking during handling process; maintain good industrial hygiene practice
Engineering Controls: Process enclosure, local exhaust, or other controls to keep airborne concentrations below exposure limits where possible
Respiratory Protection: Use NIOSH-approved mask or respirator if dust exceeds occupational exposure limits
Skin Protection: Wear chemical-resistant gloves and lab coat or apron
Eye Protection: Use safety goggles or face shield
Other Protective Equipment: Eye bath, safety shower, and hand-washing facilities in immediate area
Appearance: Orange-red crystalline powder
Odor: Odorless
Melting Point: 215–218°C
Boiling Point: Decomposes before boiling
Solubility: Practically insoluble in water, soluble in organic solvents such as chloroform or acetone
Vapor Pressure: Not applicable; solid at standard temperature and pressure
Density: Approximately 1.13 g/cm³
pH: Not applicable; not soluble in water
Flash Point: Not determined for solid; organic dust may be considered combustible
Stability: Stable if kept dry and away from direct sunlight; hydrolysis or photodegradation results in loss of activity
Chemical Stability: Zeaxanthin keeps stable under proper storage—cool, dry, protected from light
Polymerization: Hazardous polymerization does not occur based on current evidence
Conditions to Avoid: Excessive heat, direct sunlight, strong oxidizing environments
Incompatible Materials: Strong acids, bases, oxidizing agents
Decomposition Products: Thermal breakdown generates carbon monoxide, carbon dioxide, possibly other irritants in trace quantities
Acute Toxicity: Low acute oral toxicity; high-dose animal studies yield LD50 values greater than 2000 mg/kg; no acute inhalation or dermal toxicity risk found at normal exposure levels
Chronic Toxicity: No evidence for mutagenicity, carcinogenicity, or reproductive toxicity in standard models; high doses can cause skin discoloration (carotenodermia), reversible and non-toxic
Potential Health Effects: Mild eye, skin, or respiratory irritation from dust; ingestion in normal dietary amounts considered safe
Sensitization: No documented allergenic responses for properly purified zeaxanthin
Medical Conditions Aggravated by Exposure: Individuals with sensitivity to carotenoids may display mild symptoms; excessive dosing not recommended for those with rare metabolic disorders
Ecotoxicity: Zeaxanthin’s environmental persistence is low; expected to degrade through photolysis and microbial action
Persistence and Degradability: Biodegradable in soil and water, not expected to accumulate in food chains
Bioaccumulative Potential: Low; studies show minimal bioconcentration in aquatic organisms
Mobility in Soil: Binds to organic matter, little risk of leaching
Other Adverse Effects: Not considered hazardous to environment in typical use or accidental release amounts; basic containment and good clean-up practices remain recommended
Waste Disposal Methods: Dispose in approved landfill or incinerator; observe local, state, and national regulations for waste disposal
Contaminated Packaging: Rinse thoroughly before recycling or disposal, follow regulations for hazardous residues where relevant
Special Disposal Precautions: Avoid release to environment; segregate material from incompatible wastes
UN Number: Not regulated as hazardous for transport
UN Proper Shipping Name: Not classified
Transport Hazard Class: Not regulated
Packing Group: Not required
Environmental Hazards During Transport: Stable during routine shipping; not classified as marine pollutant
Special Precautions: Prevent bulk powder leaks, transport in sealed containers
International Regulation: Zeaxanthin appears on food additive, supplement, and cosmetic positive lists in many jurisdictions; not controlled as hazardous chemical under REACH, TSCA, or similar frameworks
Labeling Requirements: Product labels reference food grade status, safety data access, and proper handling instructions dependent on region
Workplace Regulation: No established OSHA PEL or ACGIH TLV; general dust exposure guidelines may apply
Country-Specific Information: Dietary supplement and addition to food regulated stringently by FDA in US, EFSA in EU, product traceability recommended for finished goods
Other Standards: GMP (Good Manufacturing Practices), ISO 9001, and food safety requirements drive supplier documentation and handling
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
