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Product Name: Xylanase
Synonyms: Endo-1,4-β-xylanase, EC 3.2.1.8
CAS Number: 9025-57-4
Recommended Use: Enzyme preparation for industrial and laboratory applications, commonly used in pulp and paper processing, food manufacturing, animal feed, and biotechnology research
Supplier Details: Manufacturer or distributor contact information found on product packaging or website
Emergency Contact: Refer to local poison control center or supplier's emergency hotline posted on the shipping document
Classification: Not classified as hazardous under GHS (Globally Harmonized System) for most typical forms, but may cause respiratory sensitization from inhaled dust
Label Elements: May include exclamation mark for respiratory or skin sensitization
Hazard Statements: May cause allergic respiratory reaction; repeated exposure may lead to sensitization; dust may irritate eyes, skin, and mucous membranes; not known to cause acute systemic toxicity
Precautionary Statements: Avoid breathing dust, use in well-ventilated areas, wear suitable protective equipment, avoid contact with eyes and skin, wash thoroughly after handling
Other Hazards: Contact with strong oxidizers may produce hazardous reactions; enzyme dust can trigger asthma-like symptoms in sensitive individuals
Substance: Xylanase protein (typically derived from Aspergillus or Trichoderma species)
Purity: Ranges from 10% to 95% active enzyme depending on formulation
Other Components: Inactive carrier (may include starch, maltodextrin, sodium chloride, or cellulose); trace fermentation by-products possible
Impurities: Protein traces from source organism, inert processing aids
Inhalation: Remove affected person to fresh air, provide oxygen if breathing is difficult, seek medical assistance for persistent coughing or respiratory distress
Skin Contact: Rinse skin thoroughly with soap and water, remove contaminated clothing, seek help for persistent irritation or allergic reaction
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do; consult medical advice if irritation persists
Ingestion: Rinse mouth, drink water to dilute, obtain medical attention for discomfort, do not induce vomiting except under professional guidance
Note for Doctor: Treat symptomatically based on clinical judgment, monitor for inflammatory or allergic responses
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Specific Hazards: Dust may form explosive mixtures with air; thermal decomposition may produce toxic fumes (carbon oxides, nitrogen oxides)
Protective Equipment: Full protective clothing, self-contained breathing apparatus recommended
Advice for Firefighters: Avoid breathing fumes or dust, keep containers cool with water spray, isolate area and minimize dust generation
Special Procedures: Contain runoff to prevent environmental contamination, clear non-emergency personnel from the area
Personal Precautions: Avoid formation and inhalation of dust, wear appropriate respiratory protection and gloves, limit access to spill area
Environmental Precautions: Prevent release into drains, surface water, or soil; contain spill with absorbents
Cleanup Methods: Collect material with vacuum equipped with HEPA filter or sweep gently, avoid dry sweeping, dispose of collected material in closed containers
Notification: Report significant releases to local environmental authorities as required; follow site-specific emergency procedures
Handling: Use with adequate ventilation, minimize dust generation, do not eat, drink, or smoke during handling; wash hands before breaks and after use
Storage: Store in a tightly sealed original container, keep in a cool, dry, and well-ventilated location away from incompatible materials (strong oxidants, acids); protect from moisture and direct sunlight
Special Considerations: Avoid repeated handling that may sensitize users, retain product in secondary containment to prevent accidental release
Occupational Exposure Limits: No established limit for xylanase, but keep airborne enzyme dust below 0.02 mg/m³ (manufacturer guideline)
Engineering Controls: Local exhaust ventilation or process enclosure to control dust levels
Protection for Respiratory System: NIOSH/MSHA approved respirator for dust/mist may be needed during dusty operations
Protection for Skin: Chemical-resistant gloves (nitrile, latex), long sleeves, lab coat or overalls
Eye/Face Protection: Safety glasses with side shields or goggles
Hygiene Measures: Wash thoroughly before eating, remove contaminated clothing after handling, clean equipment and surfaces regularly
Appearance: Fine powder or granules, white to light tan color
Odor: Faint, characteristic fermentation smell
pH (1% in water): Between 5 and 8
Melting Point/Freezing Point: Not applicable (denatures rather than melts)
Solubility: Soluble in water; insoluble in most organic solvents
Decomposition Temperature: Deactivates above 60°C; no valid boiling/melting point
Other Properties: Non-flammable as supplied; may become combustible as dust in air
Reactivity: No hazardous polymerization expected; enzyme activity lost under extreme heat or pH
Chemical Stability: Stable under recommended storage conditions, sensitive to moisture and elevated temperatures
Conditions to Avoid: Humidity, excessive heat, incompatible chemicals such as strong acids or oxidizers
Hazardous Decomposition Products: Burning may yield carbon monoxide, carbon dioxide, nitrogen oxides
Incompatible Materials: Strong oxidizers, acids, alkalis which may denature protein and pose secondary risks
Acute Toxicity: Not expected to be toxic by ingestion, inhalation or dermal exposure at typical workplace concentrations
Irritation/Corrosivity: May cause mild irritation to eyes, skin, or mucous membranes
Sensitization: Repeated inhalation or skin contact can trigger allergic response in pre-sensitized individuals (asthma, dermatitis)
Chronic Exposure: Continuous handling increases risk of respiratory or skin sensitization
Carcinogenicity, Mutagenicity, Reproductive Effects: No evidence from animal studies or workplace experience
Other Health Effects: Persons with pre-existing allergies or asthma may be at greater risk from exposure
Environmental Fate: Readily biodegradable, does not accumulate in soil or water
Toxicity to Aquatic Life: Not expected to be harmful at typical concentrations; enzyme degrades rapidly in the environment
Persistence and Degradability: Enzyme proteins degrade via hydrolysis and microbial action
Bioaccumulation Potential: None anticipated
Mobility in Soil: High, disperses in water but rapidly loses activity outside optimal conditions
Other Environmental Hazards: Large spills may cause temporary oxygen depletion from microbial growth during biodegradation
Disposal Methods: Dispose of excess product and waste in accordance with local, regional, and national regulations; incineration or landfill preferred
Contaminated Packaging: Rinse and recycle or dispose as hazardous waste if heavily contaminated
Precautions for Disposal: Avoid direct release to surface water or sewage; prevent dust and minimize environmental release during disposal
Special Instructions: Contact licensed waste disposal contractor for recommendations if required by jurisdiction
UN Number: Not classified as dangerous goods for road, air or sea transport
Proper Shipping Name: Xylanase, enzyme preparation
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Special Precautions: Protect from moisture, keep containers sealed and intact during shipment, avoid rough handling
Environmental Hazards: None known under routine conditions
Safety Regulations: Subject to OSHA (Occupational Safety and Health Administration) regulations for respiratory protection and hazard communication
Inventory Status: Included on chemical inventories such as TSCA (USA), EINECS (EU), AICS (Australia)
Labeling Requirements: Product labels must reflect possible sensitization risk and basic safe handling principles
Other Legislation: Subject to workplace exposure limits for enzyme dusts in several countries; falls under REACH in the European Union
Restrictions: Follow national and regional workplace regulations regarding biological agents and respiratory allergens
Product Registration: Consult local regulatory body or supplier for up-to-date registration and compliance status
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
