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Levamisole Hydrochloride: Essential Facts and Insights

What is Levamisole Hydrochloride?

Levamisole Hydrochloride comes up often in agricultural and veterinary circles. In labs and factories, it takes the form of a solid or powder—white to off-white, sometimes showing up as small flakes or even pearls, but rarely as a liquid unless in solution. Its official formula reads C11H12N2S·HCl, inviting curiosity among folks who want to know what goes into the raw materials used for medicines, parasite controls, or chemical synthesis. Thinking back to college chemistry, seeing that hydrochloride tag reminded me of how acids pair with organic bases to make them more stable, easier to handle, and suitable for large-scale shipping. HS Code 293499 covers it for customs, a detail I once ignored until working with import paperwork and realizing just how tightly these codes regulate the global movement of chemicals.

Physical and Chemical Properties

Levamisole Hydrochloride comes with a specific molecular weight, about 240.75 g/mol, helpful for dosing calculations, especially for pharmaceutical companies and chemical processors. The crystalline solid stands out for its soluble nature in water, making formulation easier for injectable or oral medications. Density sits roughly at 1.3 g/cm³, a little denser than typical organic powders, which makes shipping and mixing predictable for supply chain managers. Its melting point hovers between 225°C and 240°C—these high numbers ensure heat won’t break it down during packing, but those who work in high-temperature environments keep safety on their checklist. Many raw materials change color or texture over time; in my work, the best batches kept their uniform texture and didn’t clump, turning logistic headaches into smooth operations.

Structure and Material Forms

Looking at the structure, Levamisole Hydrochloride carries a thiazole ring—giving it strength in metabolic resistance, which explains its persistence in formula mixes. You find it in the lab as a powder, but some suppliers crush it to flakes for pet pharma. Factories might offer it in larger crystals or dissolve it into solutions for fast blending into other formulations. Handling each form takes planning: powder and crystals demand dust control, while solutions need sealed drums to stop evaporation and exposure. Based on my hands-on work with these materials, switching forms often depends on the next user in the chemical chain. Buyers in animal health often request high-purity powder—easy to measure, easy to store, ready for direct use.

Safe Use, Hazards, and Environmental Impact

Levamisole Hydrochloride doesn’t just stand out for its versatility, but also for its risks. Classified as harmful if swallowed or inhaled at high concentrations, it bears warnings for chemical processing plants and pharma packagers. Over the years, I’ve seen risk assessments that call for full PPE: gloves, dust masks, and eye protection reduce the chance of headaches, nausea, or more severe blood effects reported in sensitive users or those handling large batches. Material Safety Data Sheets list it as potentially hazardous, especially if accidentally released into water systems, because it can persist and impact aquatic life. While it’s not as toxic as some pesticides, routine training for safe storage, spill control, and proper disposal matters. Relying on best practices and real-life training, workers and supervisors can cut down accidents, protect surrounding communities, and ensure the chemical delivers its benefits without unintended cost.

Specification and Quality Control

Suppliers specify Levamisole Hydrochloride by purity—most batches hit at least 98% assay to fit both pharmaceutical and veterinary finished goods. Specifications also include checks for moisture (usually below 1%) and minimal impurities such as related thiazole analogs. Floaters, dust caking, or odd smells count as red flags for buyers—a lesson I learned running QA, where a single off-spec drum led to an entire batch getting pulled from a production line. Regular HPLC chromatograms, chemical analysis, and even simple visual checks help keep the supply safe. On the backend, buyers look for certificates of analysis showing conformity to standards, which builds trust and transparency up and down the delivery network.

Applications and Market Reach

Levamisole Hydrochloride sees wide use in animal health as a dewormer, but its utility stretches into research labs and the chemical industry. Synthetic pathways benefit from its predictable reactivity and reliable availability, making it a staple raw material for companies developing new drugs or refining old processes. Some global trade hinges on the compound—customs and regulators track it by the HS Code, watching for diversion, as certain gray markets misuse it as a cutting agent in illegal drugs. Strong documentation and close buyer-vendor relationships make a difference, rooting out misuses while supporting large-scale disease management for livestock or even experimental treatments in hospitals.

Responsibility and Improvements

Levamisole Hydrochloride’s blend of benefits and risks shows why more industries need to embrace full transparency and rigor—not just in documents but on the warehouse floor or in the production suite. Improving worker protections—leveraging good ventilation, prompt training, and emergency planning—directly decreases adverse incidents. Using reliable suppliers ensures close control of product integrity, supporting traceability from raw material to finished medicament. Public agencies and companies can work together by sharing best practices, updating safety guidelines regularly, and monitoring for signs of environmental impact. Looking ahead, investments in research on eco-friendlier disposal methods and alternative sourcing hold promise, and keeping up with industrial shifts means greater safety and efficiency for everyone who works with or relies on Levamisole Hydrochloride.