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Choline Chloride stands out as a quaternary ammonium salt often used in animal feed, health supplements, and chemical processing. Farmers notice positive effects when adding it to livestock rations—growth rates pick up, feed conversion improves, and animals generally look healthier. In human nutrition, it enters the scene as an essential nutrient with key roles in liver health and nerve function. Factories use it to make chemicals including methylamines and as a catalyst for certain synthetic reactions. Anyone handling this compound gets up close with its distinct crystalline form, tight white appearance, and characteristic mild amine aroma.
Anyone who’s worked with Choline Chloride begins by picking up on its structure: it comes with the chemical formula C5H14ClNO. The molecule includes a choline cation and a chloride anion, arranged in such a way that makes it highly soluble in water and polar solvents. This compound reaches the user commonly as a powder, crystal, or as solid white flakes. Sometimes there’s a demand for liquid or pearl forms, especially in industrial and feed-grade containers. Its density sits at about 1.05 g/cm3 in solid form and changes with concentration in solution. Melting comes quickly at 302°C, which keeps it stable under normal storage and transport conditions. It dissolves promptly, leaving no residue behind, and gives off a faint yet noticeable fishy odor when exposed to moisture.
Each Choline Chloride molecule contains a central nitrogen atom, which is locked into a tetrahedral geometry with three methyl groups and an ethyl alcohol arm. The chloride ion partners through ionic bonding, keeping the compound solid in most storage climates. The empirical formula C5H14ClNO details five carbon atoms, fourteen hydrogens, one nitrogen, one chlorine, and one oxygen. These combine for a molecular weight of about 139.62 g/mol. The crystalline solid breaks apart easily with water: its ions dissociate and start interacting with water molecules, which explains why it shows such speedy solubility and is rarely seen in a pure, dry state outside of sealed containers.
On the shop floor or in the lab, Choline Chloride turns up as white crystalline powder, coarse flakes, dense pearls, or as a clear liquid once dissolved. Feed manufacturers favor the powder for even mixing, while chemical plants might prefer the liquid or pearls for rapid dosing. Large-scale agriculture users look for flake or crystal versions, which resist moisture in warehouse settings. The form picked often depends on handling preferences and how fast it needs to be blended, dissolved, or stored. Liquid Choline Chloride in a clear solution covers commercial bulk use—manufacturers blend this form when preparing vast batches, saving room on storage and simplifying dosing.
Industry specs usually call for a minimum Choline Chloride content of 98% for pure powder, or 70% for liquid. Real-world testing looks for low levels of trimethylamine and other impurities. Product is sold by weight, often in 25-kg bags, bulk totes, or drums, with clear labeling on concentration and lot number. The usual Harmonized System (HS) Code for customs processing is 29231000, which places it under organic nitrogen compounds and qualifies it for feed-grade or pharmaceutical uses. Major raw materials include ethylene oxide, hydrochloric acid, and trimethylamine—these inputs drive cost, purity, and regional availability.
Choline Chloride’s density draws attention during formulation—measured at about 1.05 g/cm3 in solid state, it varies in solution depending on concentration. The solubility approaches 70g per 100ml of water at room temperature, letting it blend easily even in dense mixtures. It dissolves completely, making clear and colorless solutions, so workers in feed mills or chemical plants find little risk of clumping or clogging. Storage demands cool, dry environments and sealed packaging to stop the compound from absorbing moisture from the air. In bulk handling, the product packs tightly, avoids dust, and resists static buildup, so workers see fewer spills and batch-to-batch variation shrinks.
Choline Chloride enters the workspace as a low-toxicity chemical by design, but anyone handling the powder can feel irritation in the eyes, nose, or skin after extended contact. Proper personal protective equipment matters—workers rely on gloves, goggles, and dust masks when moving bulk product or unloading drums. Inhalation of airborne dust can cause mild respiratory discomfort in confined or poorly ventilated areas. Despite its essential role in nutrition, the chemical has its limits: high exposure can irritate, and runoff from careless storage can contaminate water or soil. Teams train for safe loading, clean spills promptly, and keep product out of reach from children and pets. Most authorities—such as the European Chemicals Agency—do not list Choline Chloride as a significant environmental or chronic health hazard, but safety data sheets recommend storing away from strong oxidizers and acids.
Growing global meat and dairy consumption keeps demand for Choline Chloride high, especially in Asia-Pacific and North America. Feed mill operators tell stories of reduced fatty liver in chickens, fast weight gain in pigs, and fewer metabolic disorders in dairy cows. Scientific research backs these claims, linking choline deficiency to growth setbacks and immune issues. In chemical processing, Choline Chloride helps make methylamines and serves as a catalyst in deep eutectic solvents—opening doors to more sustainable, less hazardous industrial procedures. Pet food manufacturers tap its nutritional strengths for premium brands, while aquaculture starts to blend it into high-protein, fast-grow fish diets.
Consistent product quality comes from strict controls on raw material supply, frequent batch testing, and up-to-date processing technology. Premix producers screen for purity, water content, and trace impurities before blending. Warehouses institute dry-room storage, frequent container checks, and train staff on handling procedures. Transparent documentation—lot numbers, certificate of analysis, and HS Codes—accelerate global shipping, reduce regulatory hiccups, and reassure downstream buyers. Waste and spill recovery plans cut environmental risk: companies collect any residual powder or solution using vacuum or absorbent pads, then dispose of according to local chemical waste guides. Collaboration between manufacturers, shippers, and buyers keeps the product effective, safe, and affordable across the supply chain.
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
