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West Ujimqin Banner, Xilingol League, Inner Mongolia, China
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Product Name: Vitamin K1
Chemical Name: Phytomenadione
Synonyms: Phylloquinone, Mephyton
CAS Number: 84-80-0
Molecular Formula: C31H46O2
Recommended Use: Nutritional supplement, pharmaceutical ingredient
Manufacturer: Common manufacturers include pharmaceutical and chemical supply companies
Emergency Contact: Provided by the supplier or manufacturer on packaging
Classification: Non-hazardous under normal conditions, though may cause mild impact if mishandled
GHS Label Elements: None required according to current global standards
Hazard Statements: May cause slight irritation on contact with eyes or skin. Not classified as carcinogenic, mutagenic, or toxic for reproduction at normal exposure levels.
Signal Word: None
Precautionary Statements: Avoid prolonged or repeated contact with skin and eyes
Other Hazards: Fine powder form may cause respiratory discomfort if inhaled
Substance: Single component
Chemical Name: Phytomenadione (Vitamin K1)
CAS Number: 84-80-0
Concentration: 98-100%, pharmaceutical or industrial grade
Impurities: Trace amounts of related compounds from synthesis, generally below 2%
Eye Contact: Rinse immediately with plenty of water. Seek medical attention if irritation develops.
Skin Contact: Wash gently with soap and water. Remove contaminated clothing.
Inhalation: Move to fresh air. Seek attention if symptoms like coughing or difficulty breathing occur.
Ingestion: Rinse mouth with water. Obtain medical help if large amounts are swallowed or if symptoms appear.
In case of exposure: Always consult medical professionals if irritation or symptoms persist.
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical, foam.
Specific Hazards: Emits noxious fumes like carbon monoxide and carbon dioxide during combustion.
Special Protective Equipment: Firefighters should wear standard protective gear including self-contained breathing apparatus.
Firefighting Instructions: Avoid breathing fumes; keep containers cool with water spray.
Explosion risk: Fine dust poses a slight risk for dust explosion if dispersed in air.
Personal Precautions: Wear gloves, eye protection, and dust mask.
Environmental Precautions: Prevent large spills from entering waterways.
Cleanup Methods: Scoop up material, place in suitable containers for recycling or disposal. Clean area with water after collection.
Disposal of Waste: Handle as pharmaceutical or chemical waste, following local guidelines.
Handling: Minimize dust formation. Use with proper ventilation. Avoid inhalation and direct contact with skin or eyes.
Storage: Store in tightly sealed containers in a dry, cool, well-ventilated location. Keep away from strong oxidizers and direct sunlight.
Incompatibilities: Avoid contact with strong oxidants.
Temperature Requirements: Controlled room temperature, typically between 15°C and 30°C.
Other Considerations: Keep away from food and drinks. Avoid contamination with incompatible materials.
Occupational Exposure Limits: No specific limit set for Vitamin K1. General nuisance dust limits may apply.
Engineering Controls: Use local exhaust ventilation if dust may be generated.
Respiratory Protection: Wear particle mask or NIOSH-approved respirator when handling powders.
Eye Protection: Use safety goggles or eye shield.
Skin Protection: Wear chemical-resistant gloves and protective clothing.
Hygiene Measures: Wash hands thoroughly after handling. Avoid eating or drinking in work areas.
Appearance: Yellow to amber crystalline powder or oily liquid
Odor: Nearly odorless
Solubility: Insoluble in water. Soluble in chloroform, ethanol, ether, and vegetable oils.
Melting Point: 5°C (liquid at room temperature)
Boiling Point: Decomposes before boiling
Vapor Pressure: Negligible
Flash Point: >113°C (elevated, use caution when heated)
Density: 0.92–0.96 g/cm3 (oily liquid)
pH: Not applicable (non-aqueous compound)
Partition Coefficient (log Kow): Greater than 8 (hydrophobic)
Chemical Stability: Stable under recommended storage conditions.
Reactivity: Avoid exposure to strong oxidizing agents.
Thermal Decomposition: May decompose on prolonged exposure to heat, forming noxious fumes.
Hazardous Reactions: No significant hazardous reactions expected with common substances.
Polymerization: Will not polymerize.
Conditions to Avoid: Excessive heat, sunlight, sources of ignition.
Acute Toxicity (Oral): LD50 (rat): >25,000 mg/kg (relatively low toxicity)
Skin Irritation: May cause mild irritation on prolonged contact.
Eye Irritation: May cause temporary discomfort.
Carcinogenicity: Not classed as carcinogen by IARC, NTP, or OSHA.
Mutagenicity: Negative in available bacterial and mammalian test systems.
Reproductive Effects: No reported adverse effects in humans at recommended doses.
Chronic Exposure: High therapeutic doses in clinical settings may impact liver or cause jaundice but not relevant for industrial handling.
Toxicity to Aquatic Life: Low. Expected to pose minimal risk given the natural occurrence and low use concentrations.
Persistence and Degradability: Biodegradable, breaks down in soil through microbial action.
Bioaccumulative Potential: Low bioaccumulation expected in aquatic organisms.
Mobility in Soil: Adsorbs to soil, not likely to leach to groundwater.
Other Effects: No signs of significant toxicity to wildlife at typical discharge or exposure levels.
Waste Handling: Collect and contain for disposal using methods consistent with local regulations.
Disposal Methods: Incineration or landfill in compliance with environmental standards.
Container Disposal: Empty containers thoroughly; recycle or dispose according to local guidelines.
Special Requirements: Prevent material from reaching waterways or sewer systems in large quantities.
UN Number: Not regulated as a hazardous material for transport.
Shipping Name: Vitamin K1, Phytomenadione
Transport Hazard Class: Not classified
Packing Group: None assigned
Environmental Hazards: Not classed as marine pollutant.
Precautions: Protect from extreme temperatures and direct sunlight during transit.
U.S. TSCA: Listed
EU REACH: Registered as a low-risk substance
OSHA: Not subject to specific workplace exposure standards
WHMIS (Canada): Not controlled
Other Regulations: Pharmaceutical and food-grade use subject to FDA and EMA oversight, depending on application.
Labeling Requirements: Reflects non-hazardous classification; standard product identification labeling should be used.
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
