Product Name: Vitamin D3 (Cholecalciferol)
Chemical Name: Cholecalciferol
CAS Number: 67-97-0
Molecular Formula: C27H44O
Synonyms: Calciol, Colecalciferol
Use: Dietary supplement, food additive, pharmaceutical ingredient
Supplier Details: Refer to product packaging for manufacturer contact and emergency number
Classification: Acute Toxicity (Oral) Category 3, Skin Irritant, Eye Irritant
Signal Word: Danger
Hazard Statements: Toxic if swallowed; can cause harm to organs through prolonged exposure; skin and eye irritation may occur
Pictograms: Skull and crossbones, exclamation mark
Precautionary Statements: Avoid inhalation, direct skin and eye contact; do not eat, drink, or smoke during use
Cholecalciferol Content: 98%-100%
Impurities: Trace related sterols and carrier oils (if present in premix)
Additive Ingredients: Commonly food-grade excipients in fortified products
Eye Contact: Flush with water for at least 15 minutes; seek medical attention
Skin Contact: Wash thoroughly with soap and water; seek care if irritation develops
Inhalation: Move to fresh air; get medical help for any breathing difficulty
Ingestion: Rinse mouth, do not induce vomiting unless instructed by a physician; immediate medical attention required for suspected overdose
Symptoms: Nausea, headache, weakness, possible hypercalcemia after large ingestion
Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam
Unsuitable Extinguishing Media: Water jets (may spread product)
Fire Hazards: Combustible at high temperatures; gives off toxic fumes (carbon oxides)
Protective Equipment: Self-contained breathing apparatus, full protective gear
Special Precautions: Avoid inhaling dust or vapor created during fire fighting
Personal Protection: Gloves, mask, eye protection
Spill Cleanup: Sweep up and place in a properly labeled container for disposal; wash area with water and detergent
Precautions: Avoid dust formation; prevent release to the environment
Handling Precautions: Limit exposure; use adequate ventilation; prevent dust formation
Storage Conditions: Store in a cool, dry, well-ventilated area; protect from light and moisture; keep container tightly closed
Incompatibilities: Strong oxidizers, acids
Packaging: Store in original containers labeled for hazard
Engineering Controls: Use local exhaust or general ventilation
Eye Protection: Safety goggles
Skin Protection: Protective gloves and clothing
Respiratory Protection: NIOSH-approved mask where dust or aerosols are present
Workplace Hygiene: Wash hands thoroughly after use; prohibit eating or drinking in work area
Physical State: White or off-white crystalline powder
Odor: Odorless
Melting Point: 83°C to 86°C
Boiling Point: Not determined (decomposes before boiling)
Solubility: Insoluble in water; soluble in fats, oils, and some organic solvents
Flash Point: Data not available
Vapor Pressure: Negligible at room temperature
Density: 0.96 g/cm³ (estimated)
pH: Not applicable (nearly insoluble in water)
Chemical Stability: Stable under recommended storage conditions; image and potency degrade with exposure to light or air
Reactivity: Does not react violently with most substances
Conditions to Avoid: Heat, light, exposure to air, strong acids and oxidizing agents
Hazardous Decomposition: Carbon oxides and toxic fumes
Polymerization: Will not occur
Acute Toxicity (Oral): LD50 in rodents: 10–50 mg/kg (high toxicity)
Skin/Eye Effects: Irritant to skin and eyes upon contact
Chronic Effects: High doses can cause hypervitaminosis D: kidney damage, calcification of soft tissue, increased blood calcium
Cancer, Mutagenicity, Reproductive: Not classified as carcinogenic, mutagenic, or reproductive hazard at normal levels
Sensitization: Not reported to cause respiratory or skin sensitization
Persistence: Moderately persistent in the environment
Bioaccumulation: Fat-soluble, builds up in living organisms
Ecotoxicity: Harmful to aquatic organisms at high concentrations
Degradability: Limited natural breakdown under sunlight and soil microbes
Waste Treatment: Dispose of contents in accordance with local, regional, national, and international regulations
Container Handling: Clean and recycle or dispose of containers as hazardous waste
Precautions: Avoid release into the environment; do not pour down the drain
UN Number: Not classified as hazardous for transport
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Special Precautions: Protect containers from physical damage, moisture, and sunlight during transit; keep tightly sealed
Regulations: Ship according to applicable environmental and safety guidelines
TSCA Status: Listed in the Toxic Substances Control Act (TSCA) inventory
EU Regulations: Registered under REACH, not classified as a hazardous chemical at food or pharmaceutical use levels
OSHA Classification: Hazardous by definition of Hazard Communication Standard
Other Standards: Complies with U.S. FDA and European food additive and pharmaceutical safety limits; worker exposure limits established in some national guidelines
Label Requirements: Includes hazard pictograms, statements of precaution, supplier identification, and directions for safe use