Contact Us
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
© 2025 Alchemist Worldwide Ltd, All Right Reserved
Product Name: Vitamin D (Cholecalciferol or Ergocalciferol)
Chemical Formula: C27H44O (Cholecalciferol); C28H44O (Ergocalciferol)
Synonyms: Calciol, Vitamin D3, Vitamin D2, cholecalciferol, ergocalciferol
Recommended Use: Nutritional supplement, food fortifier, pharmaceutical raw material
Supplier Details: Manufacturer contact information, emergency contact number, address, and website
CAS Registry Number: 67-97-0 (Cholecalciferol), 50-14-6 (Ergocalciferol)
UN Number: Not regulated under UN classification
GHS Classification: Acute Oral Toxicity (Category 4); Specific Target Organ Toxicity (Repeated Exposure), Category 2
Signal Word: Warning
Hazard Statements: May cause damage to organs through prolonged or repeated exposure if ingested; Harmful if swallowed
Precautionary Statements: Do not handle without proper training; Wash hands thoroughly after use; Wear protective gloves and eye protection during handling
Potential Health Effects: Ingestion may result in hypercalcemia, weakness, kidney dysfunction; Prolonged exposure can affect liver and kidneys
Physical Hazards: Not flammable but fine particles may become an airborne dust hazard
Environmental Hazards: Toxic to aquatic life in large concentrations; Avoid uncontrolled release to environment
Pictograms: Exclamation mark, Health hazard
Main Ingredient: Vitamin D3 (Cholecalciferol) or Vitamin D2 (Ergocalciferol)
Concentration: Usually 98% or higher for active pharmaceutical ingredient>
Impurities: Trace levels of syntheses side-products (specify per certified analysis)
Other Components: May contain stabilizers such as antioxidants in formulated products
Ingredient Disclosure: Single-ingredient for pharmaceutical grade; blended vitamins in food applications
CAS Numbers: 67-97-0 or 50-14-6 depending on D3 or D2
Inhalation: Remove from exposure, move to fresh air; seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing; wash area with soap and water; seek medical attention if irritation appears
Eye Contact: Rinse eyes slowly with water for at least 15 minutes while holding eyelids open; remove contact lenses; get medical attention if irritation continues
Ingestion: Rinse mouth with water; do not induce vomiting; get medical advice immediately
Symptoms of Overexposure: Hypercalcemia symptoms such as thirst, loss of appetite, nausea, vomiting; confusion, muscle weakness, kidney pain possible
Notes for Physicians: Treat symptoms supportively; monitor calcium levels; consider activated charcoal in acute ingestion
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or appropriate foam
Specific Hazards: May emit toxic fumes of carbon oxides under fire conditions; fine dust can form explosive mixtures in air
Unusual Fire and Explosion Hazards: Thermal decomposition can produce hazardous fumes; dust clouds may present ignition risks
Advice for Firefighters: Wear self-contained breathing apparatus and full protective gear
Additional Procedures: Cool containers exposed to fire with water mist; prevent frontline runoff into waterways
Personal Protective Equipment: Use gloves, protective goggles, dust mask or respirator
Precautions: Avoid creating dust; ventilate area; confine spill immediately
Spill Cleanup Methods: Sweep up or vacuum without raising dust; place in tightly closed containers for proper disposal
Environmental Precautions: Prevent entry into surface water, drains, or soil; alert authorities if environmental contamination occurs
Decontamination: Wash spill area with water and detergent after material removal
Handling: Avoid breathing dust; minimize dust generation and accumulation; practice good hygiene
Safe Work Practices: Use only in dedicated, well-ventilated areas; keep container closed
Storage Conditions: Store in original container tightly sealed; keep in cool, dry, and well-ventilated location away from light
Incompatibilities: Strong oxidizers, acids; avoid direct sunlight
Packaging Materials: Use light-resistant, moisture-proof containers; label appropriately
Occupational Exposure Limits: No specific limit for Vitamin D; limit airborne dust to values for nuisance particulates (10 mg/m³ total, 3 mg/m³ respirable)
Engineering Controls: Use process enclosures, local exhaust ventilation, adequate general ventilation
Personal Protective Equipment: Wear chemical-resistant gloves, laboratory coat, and safety goggles; use respirators with P1 filters for fine dust exposure
Hygiene Measures: Wash hands thoroughly after handling; do not eat, drink, or smoke in work area
Environmental Controls: Prevent accidental release to water or soil
Form: Crystalline powder or oil
Color: White to off-white or pale yellow
Odor: Odorless or faint characteristic odor
Melting Point: 83–85°C (cholecalciferol); about 115°C (ergocalciferol)
Boiling Point: Not well defined (decomposes before boiling)
Solubility in Water: Insoluble
Solubility in Solvents: Freely soluble in ethanol, acetone, fats and oils; slightly soluble in ether
Density: About 0.95 g/cm³
Partition Coefficient: log Kow approximately 8.2
Vapor Pressure: Negligible at ambient temperature
Flash Point: Not applicable
Explosive Properties: No data for pure compound; fine dust may present combustion risk
Decomposition Temperature: >100°C
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under normal use; sensitive to heat, light, and moisture
Conditions to Avoid: Excessive heat, direct sunlight, exposure to air
Incompatible Materials: Oxidizing agents, strong acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, toxic organic compounds upon combustion or decomposition
Polymerization: Will not occur under standard conditions
Acute Toxicity: Oral LD50 (rat): 10–50 mg/kg; high doses can be fatal
Skin Corrosion/Irritation: Not classified as skin irritant at low concentrations
Serious Eye Damage/Irritation: No significant irritation reported
Respiratory Sensitization: No data available
Chronic Toxicity: Prolonged ingestion at high dose results in hypercalcemia, renal impairment, calcification of soft tissues
Carcinogenicity: No evidence found in animal studies
Mutagenicity: Not considered genotoxic
Reproductive Toxicity: Excess maternal intake can cause skeletal, cardiovascular abnormalities in fetus
Other Information: Well absorbed from GI tract; accumulates in fatty tissues and liver
Ecotoxicity: Toxic to aquatic organisms in significant concentrations; may cause long-term adverse effects
Environmental Fate: Not easily biodegradable; may persist in soil and water
Bioaccumulation Potential: High due to lipophilicity; accumulates in aquatic organisms
Mobility in Soil: Low, binds strongly to organic matter
Degradability: Slowly degrades via photolysis and biodegradation
Other Adverse Effects: Vitamin D exposure in natural water systems can disrupt ecological calcium balance at very high loads
Waste Treatment Methods: Dispose in accordance with local, regional, national, and international legislation
Incineration: Suitable for high-temperature incineration under controlled conditions
Landfill: Dispose of as hazardous waste unless local regulations allow treatment as non-hazardous
Packaging Disposal: Clean, empty containers may be recycled or disposed per regulations
Contaminated Packaging: Dispose as hazardous material; avoid environmental discharge
Dilution or Neutralization: Not recommended for concentrated product
UN Number: Not regulated for ground, air, or sea transport
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Classes: Not applicable
Packing Group: Not applicable
Special Precautions: Protect from direct sunlight and moisture during transport
Environmental Hazards During Transport: Avoid spillage and contamination of watercourses
Transport in Bulk: Not subject to bulk transport regulation for dangerous substances
Labeling Requirements: Must comply with national and international food, pharmaceutical, and chemical regulations
GHS Classification: Hazardous (acute toxicity, specific target organ)
TSCA Status: Listed or exempt
EU Regulation: REACH Registered; not considered PBT/vPvB under Regulation (EC) No 1907/2006
Other Standards: Complies with US FDA, USP, EP, JP standards for food and pharmaceuticals
Restrictions: Use as food additive and supplement subject to national limits on dosage and labeling; therapeutic use governed by prescription laws
Worker Protection Standards: Employer must provide hazard awareness, safe handling instructions, and appropriate PPE under OSHA guidelines
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
