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Material Safety Data Sheet – Vitamin C (Ascorbic Acid)

Identification

Product Name: Vitamin C
Chemical Name: L-Ascorbic Acid
Molecular Formula: C6H8O6
Molecular Weight: 176.12 g/mol
Synonyms: Ascorbic acid, L-3-keto-hexuronic acid lactone
Manufacturer: Common global vitamin producers
Recommended Use: Dietary supplement, food additive, cosmetic ingredient
Contact Information: Manufacturer’s customer service or health and safety department contact lines remain open for queries regarding safety and handling.

Hazard Identification

Hazard Class: Non-hazardous for most uses, some irritation possible
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Potential Health Effects: Mild irritation to eyes, slight skin irritation, respiratory discomfort with dust inhalation, stomach upset if ingested in large doses
Signal Words: None for food-grade concentrations
GHS Label Elements: Not classified under most typical regulatory frameworks
Medical Conditions Aggravated by Exposure: Pre-existing respiratory or skin conditions may experience increased reactions
Symptoms of Exposure: Redness, tearing, coughing, sneezing, mild burning sensation in contact areas

Composition / Information on Ingredients

Chemical Identity: L-Ascorbic Acid
CAS Number: 50-81-7
Content: 99–100% pure ascorbic acid in most formulations
Impurities and Stabilizing Additives: No significant hazardous impurities expected in pharmaceutical or food-grade material
Physical Form: White or pale yellow crystalline powder or granules, odorless or faintly acidic smell

First Aid Measures

Inhalation: Move person to fresh air if dust is inhaled. Seek medical attention for breathing difficulties.
Skin Contact: Wash exposed skin with soap and plenty of water. Remove contaminated clothing; seek advice for persistent irritation.
Eye Contact: Rinse opened eye with gentle running water for at least fifteen minutes, lifting eyelids occasionally. Medical assistance for lingering irritation.
Ingestion: Rinse mouth with water if large quantities are consumed by accident. Do not induce vomiting unless directed by medical personnel. Attend medical facility if nausea or bloating persists.
Advice to Physician: Treat symptomatically. No specific antidote exists for ascorbic acid overdose, supportive care is standard.

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, CO2, water spray, or alcohol-resistant foam for fires involving this powder.
Specific Hazards: May emit carbon oxides in case of combustion, especially in confined areas. Fine powders may form explosive dust-air mixtures in rare disasters.
Protective Equipment for Fire-fighters: Full protective equipment, self-contained breathing apparatus required for major fires
Additional Information: Evacuate surrounding area, avoid inhaling combustion products, contain runoff water to prevent environmental entry of residues

Accidental Release Measures

Personal Precautions: Use dust mask, goggles, gloves during cleanup to limit direct exposure
Environmental Precautions: Do not flush excessive amounts into waterways; avoid large-scale discharge in soil
Cleanup Methods: Sweep up gently, avoid creating airborne dust, place into sealed containers for proper disposal; wash spill site with water after handling
Special Instructions: Remove ignition sources if significant dust present, ventilate concerned space thoroughly

Handling and Storage

Handling: Minimize inhalation and prolonged skin contact by using gloves, ventilation, and eye protection. Avoid generating airborne dust. Use clean, dry utensils for transfer.
Storage Conditions: Store in tightly closed, light-resistant containers away from heat sources. Stable at room temperature; refrigerate for prolonged storage.
Incompatibilities: Avoid strong oxidizers, alkalis, heavy metal salts, iron, and copper; these can cause product decomposition.
Storage Area: Keep separate from foodstuffs not meant to be supplemented. Designate cool, dry storing spaces for bulk material.
Packing Materials: Use non-reactive, airtight packaging: glass, high-quality plastic, lacquered containers preferred to maintain stability.

Exposure Controls and Personal Protection

Engineering Controls: Local exhaust ventilation keeps airborne dust at safe levels
Exposure Limits: No occupational exposure limit assigned for ascorbic acid by OSHA, NIOSH, or ACGIH; general nuisance dust guidelines apply (10 mg/m³ for total dust, 5 mg/m³ for respirable dust)
Personal Protective Equipment: Safety glasses, lab coat, dust mask or approved respirator if dust clouds form, chemical-resistant gloves
Hygiene Measures: Wash hands thoroughly after handling. Remove contaminated clothing immediately and launder before reuse.
Environmental Controls: Prevent discharge in large volumes to waterways. Maintain containment to avoid dust migration in air.

Physical and Chemical Properties

Appearance: White or slightly yellow crystalline powder
Odor: Nearly odorless with occasional faint acidic note
pH: 2.2–2.5 (50 g/L in water at 20°C)
Melting Point: Starts decomposing at 190–192°C
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Readily soluble: 33 g/L in water at 25°C; limited solubility in alcohol, insoluble in fats and oils
Vapor Pressure: Not significant at room temperature
Density: 1.65 g/cm³
Partition Coefficient (log Pow): –2.15
Autoignition Temperature: No reliable data; low risk under standard handling conditions

Stability and Reactivity

Chemical Stability: Stable under recommended storage, especially dry and cool places.
Decomposition: Releases carbon dioxide and water with heat or contact with alkalines, strong oxidizers, or light.
Reactivity: Incompatible with iron and copper salts, may discolor or degrade.
Risk of Hazardous Reactions: Product does not polymerize or react violently with common substances under proper storage; risk appears under very strong oxidizers.
Conditions to Avoid: Exposure to heat, direct sunlight, humid air, and contact with reactive metals or oxidants.

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD50 (oral, rat): above 11,900 mg/kg; generally low risk from acute single exposure
Chronic Effects: High repeated doses may contribute to kidney stone formation or gastrointestinal upset. No known carcinogenicity, mutagenicity, or reproductive toxicity.
Skin/Eye Effects: Mild local irritation possible; no reports of severe injury in normal handling
Inhalation: Temporary respiratory tract irritation likely at high concentrations of airborne dust
Sensitization: No significant evidence for immunological sensitization

Ecological Information

Aquatic Toxicity: Not expected to cause environmental toxicity at typical concentrations; breaks down quickly in water and soil
Persistence and Degradability: Readily biodegradable, both by microbial action and by abiotic degradation pathways
Bioaccumulation Potential: Not a concern; low potential for accumulation in wildlife
Soil Mobility: Moves freely in water, but degrades rapidly in presence of oxygen and light
Other Adverse Effects: No adverse ecological impact observed in studies; non-persistent, non-toxic for most micro- and macro-organisms

Disposal Considerations

Methods of Disposal: Small quantities can go with normal waste due to low risk; large volumes should be disposed in accordance with local, regional, or national regulations for organic chemicals.
Precautions: Avoid discharge of powder to public water treatment or sewage systems in bulk.
Packaging Disposal: Empty packaging should be washed and recycled or landfilled as non-hazardous waste unless contaminated by other substances.
Sewage Disposal: No significant risk for water treatment, but discourage excessive disposal to maintain best environmental practices.

Transport Information

UN Number: Not regulated for ground, air, or sea transport
Transport Hazard Classes: None assigned; product classified as non-dangerous
Packing Group: Not applicable
Label Requirements: No hazard label requirements for typical grades
Special Precautions: Keep containers tightly sealed and protected from excess moisture or mechanical shock during transportation
Bulk Shipping: Avoid exposure to heat and sun, keep away from incompatible cargo such as oxidizers

Regulatory Information

U.S. Regulations: Not subject to reporting under SARA Title III Section 313, not listed as a hazardous waste under RCRA, generally recognized as safe (GRAS) by FDA for designated food uses
EU Regulations: Not classified as dangerous under Regulation (EC) No. 1272/2008 (CLP); listed on EINECS
Other Countries: Compliant for import, production, use in food and pharma in Canada, Australia, Japan, under corresponding regulations
Labeling: Typically labeled for intended use, purity, storage, safety recommendations; not classified as restricted or hazardous
Restrictions: No specific consumer or workplace restrictions for pure preparation in food, supplement, or cosmetic application categories