Product Name: Vitamin B12
Chemical Name: Cyanocobalamin
CAS Number: 68-19-9
Formula: C63H88CoN14O14P
Usage: Used for dietary supplements, food fortification, clinical nutrition formulas
Supplier Contact: Company safety department, phone and emergency numbers provided on logistics documentation
Recommended Use: Laboratory, pharmaceutical, nutraceutical, animal feed
Restrictions: Not for use in explosive atmospheres or where respirable dust is generated purposelessly
Main Risk: May cause minor eye or skin irritation in sensitive individuals
Hazard Symbol: None required under GHS for typical forms
Signal Word: None
Inhalation: May cause discomfort, coughing if large amounts are inhaled
Ingestion: Considered safe in recommended amounts; large scale ingestion uncommon and rarely hazardous
Skin Contact: Possible allergic reaction in rare cases
Chronic Effects: No evidence of carcinogenic, mutagenic, or reproductive toxicity features in humans
Environmental Hazard: Not classified as dangerous to environment in standard concentrations
Cyanocobalamin (Vitamin B12): pure, >98% by most suppliers
Impurities: Trace heavy metals, moisture, and stabilizers below warning thresholds
Other Components: None typical for reagent or raw powder forms
Allergens: None expected from synthetic or fermentation-based industrial production
Inhalation: Move to fresh air, support breathing if difficulty continues, seek medical advice for persistent symptoms
Skin Contact: Rinse with running water, remove contaminated clothing, wash hands thoroughly
Eye Contact: Flush gently with water for at least 10-15 minutes, remove contact lenses if present, seek attention for redness or discomfort
Ingestion: Rinse mouth, drink water if conscious, seek medical help with large accidental doses
Advice for Doctors: Treat symptomatically; known allergies rare but possible
Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Special Hazards: Dust can burn with strong heat, decomposition at high temperatures gives off carbon oxides and nitrogen oxides
Protective Equipment: Use full protective clothing and breathing apparatus if exposed to smoke or decomposition fumes
Fire-Fighting Guidance: Contain water run-off to prevent environmental release; product does not sustain fire but may auto-ignite as fine dust in rare, extreme heat cases
Personal Precautions: Avoid breathing dust, use goggles and gloves during cleanup
Environmental Precautions: Prevent entry into waterways and sewers, minimize spread of dust
Cleanup Methods: Use HEPA-filtered vacuum or wet methods to collect powder, avoid raising clouds, wipe down with wet cloth
Waste Disposal: Place solid waste in sealed containers for disposal according to local regulations
Handling: Wear protective equipment to prevent unnecessary contact, avoid creating fine dust, wash hands after use
Storage: Keep container sealed, store in a cool, dry, well-ventilated place, protect from moisture and light
Compatibility: Store away from strong oxidizing agents and acids
Spill Response: Clean up promptly, do not mix with incompatible chemicals
Exposure Limits: No official occupational exposure limits for Vitamin B12
Engineering Controls: Handle in well-ventilated area, use dust extraction systems for bulk powder
Personal Protection: Nitrile gloves, safety glasses, dust mask or respirator for large quantities
Hygiene Measures: Wash hands before eating, drinking, or leaving laboratory, change clothes if powder exposure occurs
Environmental Controls: Prevent dust escape from work area
Appearance: Dark red to brown crystalline powder
Odor: Odorless or faint characteristic odor
pH: Neutral to slightly acidic in aqueous suspension
Solubility: Water soluble, slightly soluble in alcohol, insoluble in ether and chloroform
Melting Point: Decomposes above 230°C
Boiling Point: Not applicable (decomposes)
Vapor Pressure: Not measurable for solid powder
Relative Density: About 1.35 g/cm³
Particle Size: Variable, typically micron to sub-millimeter for bulk powders
Chemical Stability: Stable under normal temperature and storage conditions
Decomposition: Decomposes on heating, light exposure accelerates breakdown, releases toxic fumes (CO, NOx) at extreme temperatures
Incompatible Materials: Strong oxidizing agents, strong acids, bases
Hazardous Polymerization: Does not occur
Reactivity: Low under standard worksite conditions
Acute Toxicity (Oral, LD50): Greater than 5000 mg/kg in rats; low toxicity profile in humans
Chronic Toxicity: No carcinogenic or mutagenic effects found in repeat studies
Routes of Exposure: Inhalation of dust, accidental ingestion, skin, or eye contact
Symptoms: High doses may cause mild gastrointestinal upset or allergic skin reactions
Sensitization: Rare cutaneous and respiratory allergens reported in sensitive workers
Epidemiology: B12 toxicity extremely rare; mostly associated with excessive supplementation in clinical error
Ecotoxicity: Not expected to bioaccumulate or persist in aquatic environments
Aquatic Toxicity: No evidence of harm to fish, crustaceans, or algae at realistic environmental concentrations
Mobility: Dissolves in water; low soil adsorption expected
Degradability: Biodegrades rapidly under warm, aerobic conditions
Bioaccumulation: Unlikely; metabolized rapidly by soil and water microorganisms
Waste Treatment: Dispose of as non-hazardous organic waste if uncontaminated; follow local environmental regulations for disposal
Incineration: Possible for large scale expired industrial materials
Disposal Containers: Use sealed, clearly labeled packaging
Spill Cleanup Waste: Treat as laboratory chemical solid waste, avoid landfill if possible due to energetic breakdown in waste piles
UN Number: Not regulated for transport
Proper Shipping Name: Vitamin B12, Cyanocobalamin
Hazard Class: Not classified as hazardous for road, rail, sea, or air transport
Packing Group: None
Marine Pollutant: No
Special Precautions: Protect from extreme heat, sunlight, physical damage during transit
GHS Classification: Non-hazardous under typical regulations
TSCA Listing: Listed in the United States Toxic Substances Control Act inventory
DSL/NDSL Status: Listed in Canada’s Domestic Substances List
OSHA: Not classified as hazardous in workplace quantities
EU Regulations: Listed under EINECS/ELINCS, not classified as hazardous
Other Standards: Complies with food, pharma, and health supplement regulations in US, EU, Asia (reference manufacturer compliance documents)