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Trimethoprim found its footing among infectious disease treatments in the late 1960s, just after its big cousin, sulfonamides, had lost some steam due to resistance. Chemists first designed this compound to target bacterial dihydrofolate reductase, brushing up against bacteria’s ability to flourish by interfering with folate metabolism. During the early push for antimicrobial agents after penicillin’s discovery, researchers kept hunting for smaller, less toxic, and more focused alternatives. Trimethoprim answered that call by offering action against a wider variety of urinary tract pathogens. When combined with lactate to form trimethoprim lactate, the product traveled more smoothly through the body and labs saw fewer complications during administration. Old reports from randomized trials made it clear: trimethoprim lactate held promise as a streamlined solution when sulfa drugs stalled or allergies came up.
Trimethoprim lactate shows up as a crystalline, nearly white powder. Manufacturers measure every last bit of impurity using high-performance liquid chromatography, so clinics get a product fit for human use. The binding with lactic acid makes dosing by mouth more reliable, and that means fewer headaches for pharmacists when designing regimens for daily or intermittent use. After years of adjustments, products offer dependable shelf-life and can be blended with other agents or placed into various forms for customized prescription. Major suppliers standardize the compound’s purity above 98%, which eliminates guesswork about what’s going into patients’ bodies.
Trimethoprim lactate’s physical characteristics reflect its molecular heritage. The off-white crystals dissolve better in water than their parent form, opening up options for liquid suspension, intravenous infusions, and pediatric delivery. Technicians gravitate toward its clean melting point, holding steady around 220°C, which helps during batch testing and stability trials. With a molecular formula of C14H18N4O3.C3H6O3, trimethoprim lactate walks the line between fat-soluble and water-soluble, riding the strengths of both in drug design and storage.
Every commercial batch includes labeling requirements driven by regulators in the US, EU, and Asia. Labels spell out precisely what’s inside—trimethoprim base and the amount of lactate. Pharmacopeias lay down specific codes, whether published by the United States Pharmacopeia or the European Medicines Agency. Packaging teams describe recommended storing at 2-8°C and in dry, light-shielded environments, keeping potency steady. Barcodes and tracking systems map each product’s trail from plant to pharmacy, aiming for traceability. Regulatory authorities catalog adverse event reporting info directly on the label, so nobody gets left out of the loop in case of unexpected reactions.
Synthesis of trimethoprim lactate starts from 3,4,5-trimethoxybenzaldehyde, which undergoes condensation to join with the pyrimidine ring, producing the trimethoprim core. After purification, the team introduces lactic acid under controlled conditions, avoiding harsh solvents to stay compatible with pharmaceutical standards. Chemists favor batch processing over continuous blends, preferring the ability to test and tweak as the product moves from flask to tablet or vial. Quality control analysts verify each step using spectroscopic and chromatographic techniques to guard against contamination, which protects both patients and reputation.
The most important trimethoprim reactions involve substitutions on the pyrimidine or anisole groups. Modifying these positions tweaks the strength against resistant bacteria or fine-tunes absorption rates for special patient groups. Often, newer versions swap the classic lactate salt for mesylate or phosphate, trading off solubility against stability, responding to shortages or pricing shifts in industrial chemistry. Through chemical analysis, teams examine how each version interacts with enzymes and human metabolic pathways, getting ahead of new resistance patterns seen in real-world outbreaks.
On the market, trimethoprim lactate shares shelf space with labels like Proloprim and Trimpex. Technical documents call it by system names such as 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine lactate salt. Pharmacists order by NDC codes, clinicians jot recommendations on charts, and drug safety professionals send alerts by yet another alias. This complexity sometimes leads to confusion across borders but tight coordination between regulators and importers helps avoid dispensing errors.
Direct safety studies on trimethoprim lactate point to strong tolerability profiles in adults. Dosing guidelines emphasize the risks among users with kidney trouble, recommending close monitoring and, in some cases, dose adjustments. In the workplace, manufacturers rely on protective gear and advanced ventilation to shield employees from airborne particles. Hospitals and clinics keep trimethoprim lactate in segregated cabinets to avoid accidental cross-contamination, guided by exacting standards written in current good manufacturing practice (cGMP) manuals. Product recalls rarely occur, a testament to robust controls.
Trimethoprim lactate surfaces most often in treatment of urinary tract infections, acute bronchitis, and sometimes certain gastrointestinal bugs. It forms one half of the famous co-trimoxazole duo, joined with sulfamethoxazole in what’s widely recognized as Bactrim—a combination still in use for Pneumocystis pneumonia in immunocompromised patients, including those living with HIV. Veterinary clinics see value, too, turning to trimethoprim lactate for respiratory and stomach infections in dogs and horses. Overuse signals rising resistance, especially where self-medication and over-the-counter sales go unchecked. As physicians keep a close eye on shifting patterns, they rely on this agent when old solutions won’t do.
Researchers in academic and private labs have chased modifications that stretch the spectrum or reduce side effects. Grants funnel toward trials that combine trimethoprim lactate with modern agents targeting multidrug resistant pathogens. Teams track genetic adaptations in E. coli and Klebsiella, hunting molecular features that point to emerging resistance and looking for diagnostic tools to guide smarter prescribing. High-throughput screening platforms and machine learning help discover new derivatives, with some candidates pushing onto the patent stage each year. Open data and public registries ensure discoveries remain visible beyond the pharmaceutical heavyweights.
Dosing experiments in rodents, dogs, and ultimately humans uncovered a reassuring safety window for trimethoprim lactate. Reports stretch back decades, uncovering rare allergies, photosensitivity, and, in vulnerable populations, risk of blood count drops or electrolyte disturbances. Toxicologists call for longer studies in children and genetic subgroups because they react differently than healthy adults. Ongoing research tracks the drug’s impact on gut flora and links to secondary infections—concerns that gained attention as broad-spectrum antibiotics became routine. Regulatory agencies demand post-market surveillance, and electronic health records help clarify rare complications, supporting pharmacovigilance at the population level.
Trimethoprim lactate faces challenges from two fronts: climbing resistance and the high bar set by pharmaceuticals’ next wave. To stay relevant, development will need new delivery systems—think nanoparticles, slow-release tablets, or advanced topical gels. Teams look at combining this classic agent with bacteriophages or new enzyme blockers tailored to today’s hard-to-kill bugs. Global health policy makers advocate for stricter stewardship, tighter controls on sales, and education for frontline clinicians to fend off the worst of resistance. In many clinics across developing regions, though, affordable and familiar agents like trimethoprim lactate still carry much of the load, connecting decades of experience with future investment in smarter, targeted infection fighting.
Walk into any busy clinic, and sooner or later, someone walks out with a prescription for an antibiotic. Trimethoprim Lactate pops up in those conversations with both doctors and pharmacists, usually tied to treating bacterial infections. My own encounters with this drug didn't start in a hospital, but over the counter, answering friend’s questions about what fights off urinary tract infections (UTIs). It's a straightforward medicine with a clear job—helping the body knock out the bacteria that turn basic illnesses into nagging, disruptive problems.
Most people meet Trimethoprim in the context of UTIs. Studies show that nearly half of all women experience at least one UTI during their lifetime. Fast, clear action from antibiotics shapes the difference between a simple fix and days of discomfort. The medicine works by stopping bacteria from producing the folic acid they need to survive and spread. By cutting off this supply, it checks bacterial growth. In my own community, doctors have told me they prefer this medication in areas where resistance isn’t a constant battle, and it’s well tolerated by patients who can’t take other options like sulfonamide drugs.
No two infections look exactly alike, so context drives who actually benefits from Trimethoprim. Some folks do better with it than others. For basic bladder infections, it gets the job done efficiently. Growing up, my grandmother depended on it to avoid hospital stays. In kids, pediatricians lean on this treatment, especially when others cause allergy flare-ups. Immune-compromised patients benefit because it can prevent infections beyond the urinary tract, such as certain types of pneumonia, when paired with other medicines. The key: doctors need access to a full picture of each patient’s health and background. Too many people self-prescribe or skip follow-ups, and that’s where trouble brews—overuse can breed antibiotic resistance.
There’s hardly an antibiotic left unscathed by resistance. I’ve watched experienced doctors change up old routines when standard medications stop working. Bacteria evolve quickly. The Centers for Disease Control and Prevention (CDC) notes a steady increase in antibiotic-resistant UTI cases. Trimethoprim still works well in many communities, but only if prescribers think before reaching for it. Pharmacists, nurses, and patients—everyone shares a piece of responsibility. Without careful use, the day comes when simple infections demand stronger, costlier, or more harmful drugs.
Plenty of folks in healthcare now spend as much energy teaching patients about antibiotics as they once did writing prescriptions. Simple steps like finishing a course of antibiotics, reporting allergic reactions, or not sharing leftover pills help keep medicines like Trimethoprim useful for the long term. My own conversations with patients, friends, and family often center around driving home those habits. Clinicians encourage urine cultures before treatment to target infections accurately. Hospitals routinely audit their practices, tighten up guidelines, and keep up with new research to stay one step ahead of resistance.
The story behind Trimethoprim Lactate stretches far beyond a single pill or prescription. At its core, it’s about finding balance between immediate relief and long-term safety. That means using antibiotics only when they’re needed, understanding individual needs, and preparing for a future where not every solution comes from a bottle. Health education, smarter prescribing, and research into new medicines shape a landscape where effective medical care stays within reach—for everyone.
Doctors sometimes prescribe trimethoprim lactate to deal with bacterial infections, especially in the urinary tract. It works by interfering with the bacteria’s ability to make essential proteins. No medicine is without its baggage, though. Side effects, even with something as tried-and-true as trimethoprim lactate, catch plenty of people off guard. Having spent time with family members—and myself—taking antibiotics over the years, these side effects aren’t just textbook material. They show up in real bathrooms, at late-night medicine cabinets, and in chats with pharmacists.
Most folks taking trimethoprim lactate spot troubles in the gut first. Think about nausea that refuses to let up or an upset stomach that flares up at the worst moments. Diarrhea makes workdays tough or interrupts sleep. Sometimes, a mild stomach ache trails through the day. According to a study in the Journal of Antimicrobial Chemotherapy, up to 10% of people using trimethoprim report at least one digestive issue. No one likes running to the bathroom. For those who push through, bland meals, smaller portions, and keeping hydrated seem to help. If diarrhea gets intense or blood shows up, that’s a signal to get on the phone with the doctor right away.
Rashes can sprout up after a few doses, sometimes looking like measles and feeling itchy. For some, facial swelling or trouble breathing comes on strong. My own neighbor ended up in the emergency room because she thought a gentle rash would fade, but it turned out she needed urgent care. Allergic reactions can flip the script from daily annoyances to life-threatening emergencies. That’s why medical guidance points out the need to flag hives, swelling, or wheezing as must-report problems. The Food and Drug Administration stresses the danger of severe skin reactions like Stevens-Johnson syndrome—rare, yes, but devastating without fast treatment.
Blood moves quietly under the radar until medications stir things up. Trimethoprim lactate sometimes drops the number of white or red blood cells, especially in folks already dealing with deficiencies or older adults. Symptoms like unexpected bruising, bleeding gums, or a sense of being unusually wiped out deserve attention. Clinics can check blood levels with a simple test. Those who need long courses should ask if blood monitoring is wise. It’s not paranoia—it’s prevention.
Most people won’t face kidney issues, but it can happen, especially for those who already fight with kidney troubles. Monitoring urine color and noticing swelling or less frequent urination keeps problems from building up unnoticed. Muscle weakness or odd tingling sensations also make the rare list but call for a direct word with a healthcare provider. Kids, pregnant women, and those on other medications land at higher risk. The combination of age, underlying illness, and drug interactions can shift the balance.
Nobody gets a guarantee with side effects. Honest talks with a doctor or pharmacist help put risks in context. Asking questions—"Could this medicine clash with others I take?" or "What should I watch out for?"—can change outcomes. The more real stories get shared, the less people get blindsided by side effects that textbooks mention but real life magnifies.
Trimethoprim Lactate works as an antibiotic, usually fighting off bacteria in the urinary tract or sometimes in other parts of the body. I once caught a stubborn UTI during a busy week at work and my doctor prescribed Trimethoprim. That prescription demanded my attention every single day, and missing a dose made all the difference.
Doctors usually want you sticking to a schedule: one pill every twelve hours, not when you feel like it. Setting a reminder on my phone helped a lot. I learned the hard way that taking antibiotics like Trimethoprim only when convenient lets bacteria regroup, and then the bug might not go away at all or might even come back stronger. Science backs that up—partial courses of antibiotics build resistance because not all bacteria die off. The CDC reported more than 2.8 million antibiotic-resistant infections in the United States each year, making this advice more than just a suggestion.
Trimethoprim Lactate doesn’t always bother the stomach, but indigestion can sometimes kick in. You can take it with or without food, but eating alongside the pill can help if nausea shows up. My neighbor, who took pills on an empty stomach, ended up with cramps and stopped the course. She eventually had to go back to the doctor for stronger medication.
Drinking water isn’t just a good habit in general—it helps flush the bacteria out, especially during a UTI. At least one full glass with every dose kept things moving for me and made the symptoms feel less intense.
Forgetting a dose throws the schedule off. If you miss a pill, take it as soon as you remember, but not if the next dose is already close. Doubling up sounds tempting but can push the body too far, leading to more side effects instead of better results.
Trimethoprim can cause rashes, itching, or sore throats in some people. I once broke out in hives that didn’t fade after a few hours. Whenever something weird happened, I called the clinic instead of toughing it out. Safety should outweigh embarrassment or inconvenience.
Symptoms might disappear, but quitting early can put you right back where you started. Even after the burns and pains faded, I kept going until the bottle was empty. Stopping early meant risking a return trip to the doctor’s, which sometimes costs more than just time.
Not all antibiotics suit every person. Kidneys play a big role in clearing out this kind of medicine. Regular check-ins, even just over the phone, allowed me to catch and talk about side effects. People with kidney trouble, older adults, and pregnant women might need different advice. Honest conversations lead to tailored plans, not one-size-fits-all routines.
Following the doctor’s instructions takes priority, even if it feels repetitive. Reaching out for advice isn’t a sign of weakness. I found out early that open discussions save stress down the road and result in a healthier recovery.
Trimethoprim, a regular face in the world of antibiotics, often steps in to clear up urinary tract infections. The risks don’t stop at side effects like skin rashes or a bit of stomach upset. Start stacking it with other drugs, and things can get complicated fast — the body isn’t just a test tube, and one person’s harmless mix turns into another’s big problem.
On a day when the pharmacy is crowded and people just want to get in and out, it’s easy to grab a prescription and not give a second thought to what’s already at home. Blood pressure pills, water tablets, painkillers, even those “natural” vitamins — any of them can throw a wrench in a treatment plan. Trimethoprim doesn’t play well with all of them.
Most folks don’t realize potassium can sneak up and cause trouble. Trimethoprim can hold potassium in the body. So can drugs called ACE inhibitors and ARBs—found inside lots of blood pressure medicines, things like lisinopril or losartan. Add in water pills like spironolactone, and that potassium number risks inching up too high. There have been news stories about people landing in the hospital with heart rhythm problems from this exact cocktail.
People on warfarin, the gold-standard blood thinner, know their blood tests by heart. Trimethoprim can make warfarin work too well, so that even a small scratch could mean real trouble. The British Medical Journal once pointed out that this pairing really ramps up bleeding risks, especially in older adults.
Epilepsy medicines demand their own attention. Phenytoin, which helps to keep seizures in check, gets a bump in the blood when trimethoprim joins in. What follows? Headaches, confusion, trouble walking — all thanks to phenytoin levels climbing too high. Sharing all meds with the pharmacist helps head off these domino effects.
Doctors and pharmacists walk a careful line, yet patients slip through cracks. Many skip telling their healthcare team about a supplement or a drug from a different doctor. I saw a neighbor get rushed to urgent care for what turned out to be sky-high potassium. She didn’t connect her new antibiotic to her daily water pill — nobody told her these could clash.
The U.S. Food and Drug Administration keeps an updated list of drug interactions for a reason. Trimethoprim links arms with methotrexate, sometimes driving up the risks of bone marrow problems. Even diabetes drugs can run into trouble — certain sulfonylureas, for example, can dip blood sugar lower than expected. Lab work, careful monitoring, and clear conversations keep more folks out of trouble.
Nobody wants to end up back at the doctor because of a medicine mishap. Honest talks with doctors and pharmacists build a safety net. Instead of folding up the printout with the new prescription and stuffing it in a bag, take a minute to ask questions. Each person’s body works its own way, and what goes smoothly for one can leave another in a bind. At the end of the day, keeping trimethoprim from causing more harm than good rests on sharing the whole story about prescriptions, over-the-counter remedies, and even those wellness supplements.
Simple action: check your meds, ask the hard questions, and don’t try to juggle these details alone. The stakes are just too high.
Trimethoprim lactate steps up as a strong tool against bacterial infections. Not everyone can count on this medicine, though. I’ve seen friends, family, and plenty of people in pharmacies run into trouble because they didn’t realize these antibiotics can work against your body instead of for it under some conditions.
Anyone who’s had an allergic response to trimethoprim or similar sulfa drugs can land in the emergency room after taking this medicine. I remember a neighbor breaking out in hives so badly she needed urgent care—turns out she had a history with sulfa allergies and didn’t recognize the risk. It’s not just a bad rash; these reactions can close airways or cause severe all-over inflammation. If there’s any doubt, allergy testing or speaking up with a doctor clears it up.
Trimethoprim can interfere with folic acid metabolism. During pregnancy, folic acid supports normal growth for the baby’s brain and spine. Mess with that, and you increase the odds of birth defects. Mothers-to-be, or even women trying for a baby, steer away from this drug unless the doctor gives a really convincing reason. Nursing moms also face a risk—the drug can end up in breast milk and possibly throw off a baby’s blood cell balance.
People living with megaloblastic anemia or other blood-related issues, especially if caused by a lack of folic acid, hit a hard stop with trimethoprim. This drug blocks folic acid, making anemia worse. I’ve seen the difference in blood test results; the drops in red blood cells after using the wrong antibiotic aren’t just numbers—they leave folks feeling tired and short of breath. Diagnosed blood disorders, especially from folate deficiencies, call for alternatives.
Healthy kidneys and livers act as body filters, clearing out medicine after it’s finished its job. Kidneys on the fritz or a struggling liver can’t flush trimethoprim efficiently. The drug then builds up, raising toxic side effects. People with reduced kidney or liver function, especially elderly patients, can tip into dangerous territory—not by choice, just by trying to clear an infection. Most doctors check kidney and liver values, but patients should always speak up about their medical history.
Some drugs clash pretty badly with trimethoprim. Blood thinners like warfarin can act up, raising risk for bruises or uncontrolled bleeding. If somebody takes medicines that boost potassium (like some heart pills or certain diuretics), pairing them with this antibiotic can crank potassium to unsafe levels. Too much potassium leads to heart rhythm issues—nothing to mess with. It pays to keep a current list of all medications, and talk through it with a healthcare professional. One overlooked pill can bring big trouble.
People use antibiotics hoping for quick help, but a quick fix isn’t worth long-term harm. I’ve watched patients find safer roads—maybe a different antibiotic, or waiting for lab results before jumping on a prescription. Open conversations with a doctor, along with clear records of allergies and illnesses, set the stage for better health. There’s always another choice worth exploring if the risks feel too high with trimethoprim lactate.
| Names | |
| Preferred IUPAC name | 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine 2-hydroxypropanoate |
| Other names |
Lactate de triméthoprime Trimethoprimum lactas Trimethoprim lactas Trimethoprim lactate |
| Pronunciation | /traɪˈmɛθ.ə.prɪm ˈlæk.teɪt/ |
| Preferred IUPAC name | 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine 2-hydroxypropanoate |
| Other names |
Trimethoprim lactic acid Trimethoprim lactate salt Lactate de trimethoprim |
| Pronunciation | /traɪˈmɛθ.ə.prɪm ˈlæk.teɪt/ |
| Identifiers | |
| CAS Number | 23256-42-0 |
| Beilstein Reference | 2121843 |
| ChEBI | CHEBI:9507 |
| ChEMBL | CHEMBL1435 |
| ChemSpider | 31468339 |
| DrugBank | DB00440 |
| ECHA InfoCard | ECHA InfoCard 100.126.151 |
| EC Number | 239-754-6 |
| Gmelin Reference | 517416 |
| KEGG | C07484 |
| MeSH | D000933 |
| PubChem CID | 22334980 |
| RTECS number | SZ9950000 |
| UNII | E135R8T2CK |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DTXSID4071885 |
| CAS Number | 23256-42-0 |
| 3D model (JSmol) | kekule=NC1=NC(N)=NC(C2=CC=CC(OCC(CO)N)=C2)=N1 |
| Beilstein Reference | 2158986 |
| ChEBI | CHEBI:9536 |
| ChEMBL | CHEMBL1378 |
| ChemSpider | 4407986 |
| DrugBank | DB00440 |
| ECHA InfoCard | 03e74b98-cee3-48c2-840d-3124e4beecd8 |
| EC Number | EC Number: 258-872-2 |
| Gmelin Reference | 84117 |
| KEGG | C07413 |
| MeSH | D014244 |
| PubChem CID | 124025 |
| RTECS number | GR3225000 |
| UNII | R8E2U1L4TX |
| UN number | UN3249 |
| CompTox Dashboard (EPA) | DTXSID1040288 |
| Properties | |
| Chemical formula | C14H18N4O3 · C3H6O3 |
| Molar mass | 366.39 g/mol |
| Appearance | White or almost white crystalline powder |
| Odor | Odorless |
| Density | 1.35 g/cm³ |
| Solubility in water | Soluble in water |
| log P | 0.94 |
| Acidity (pKa) | 7.12 |
| Basicity (pKb) | 7.24 |
| Refractive index (nD) | 1.61 |
| Dipole moment | 3.7273 D |
| Chemical formula | C14H18N4O3 · C3H6O3 |
| Molar mass | 366.39 g/mol |
| Appearance | White or almost white crystalline powder |
| Odor | Odorless |
| Density | 1.45 g/cm3 |
| Solubility in water | Slightly soluble in water |
| log P | 0.91 |
| Acidity (pKa) | 7.12 |
| Basicity (pKb) | 13.1 |
| Magnetic susceptibility (χ) | -7.1×10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.62 |
| Dipole moment | 4.06 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 393.7 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -669.8 kJ/mol |
| Pharmacology | |
| ATC code | J01EA01 |
| ATC code | J01EA01 |
| Hazards | |
| Main hazards | May cause allergic reactions, skin and eye irritation, and serious adverse effects if swallowed or inhaled. |
| GHS labelling | GHS02, GHS07 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H302: Harmful if swallowed. |
| Precautionary statements | P264, P270, P273, P280, P301+P312, P305+P351+P338, P337+P313, P501 |
| NFPA 704 (fire diamond) | 1,2,0 |
| Lethal dose or concentration | LD50 oral, rat: 1,640 mg/kg |
| LD50 (median dose) | LD50 (median dose): 1850 mg/kg (oral, mouse) |
| NIOSH | VQ7H640DZI |
| PEL (Permissible) | PEL: Not established |
| REL (Recommended) | 300 mg |
| Main hazards | May cause allergic skin reaction, eye irritation, and respiratory irritation. |
| GHS labelling | GHS05, GHS07, Danger, H318, H302, P280, P305+P351+P338, P310 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | Hazard statements: Causes skin irritation. Causes serious eye irritation. |
| Precautionary statements | Store locked up. Store in a well-ventilated place. Keep container tightly closed. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Dispose of contents/container in accordance with local/regional/national/international regulations. |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | 118°C |
| Lethal dose or concentration | LD₅₀ (oral, rat): 1590 mg/kg |
| LD50 (median dose) | LD50 = 1380 mg/kg (oral, mouse) |
| NIOSH | GN3508000 |
| PEL (Permissible) | Not Established |
| REL (Recommended) | 160 mg |
| IDLH (Immediate danger) | Not established |
| Related compounds | |
| Related compounds |
Trimethoprim Trimethoprim Phosphate Trimethoprim Sulfate |
| Related compounds |
Trimethoprim Trimethoprim hydrochloride Trimethoprim sulfate |
