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Material Safety Data Sheet (MSDS) for Titanium Dioxide

Identification

Product Name: Titanium Dioxide
Chemical Name: Titanium(IV) oxide
Synonyms: Rutile, Anatase, Titania, TiO2
CAS Number: 13463-67-7
Recommended Uses: Pigment in paints, coatings, plastics, paper, inks, food coloring
Supplier Information: Manufacturer or distributor contact required by end user
Emergency Contact: Local or national emergency number as specified by workplace policies

Hazard Identification

Classification: Not classified as hazardous under GHS for most uses; IARC classifies certain dust forms as possibly carcinogenic to humans (Group 2B)
Signal Word: None
Hazard Statements: Dust can be irritating to eyes, respiratory tract, and skin by mechanical action
Health Risks: Prolonged inhalation of respirable dust could possibly increase cancer risk
Precautionary Statements: Wear suitable personal protection, minimize dust generation, avoid breathing dust
Label Elements: None expected under current regulations for typical product grades

Composition / Information on Ingredients

Ingredient: Titanium Dioxide
CAS Number: 13463-67-7
Concentration: Usually above 99%
Impurities: Trace amounts of alumina, silicate, iron, or silica sometimes present depending on manufacturing
Additives: Surface treatments such as silica or alumina may be applied, and content varies by supplier

First Aid Measures

Inhalation: Move affected person to fresh air; seek medical attention if coughing or respiratory symptoms develop
Skin Contact: Remove contaminated clothing as needed; flush skin with water and soap as needed
Eye Contact: Rinse immediately with water for several minutes; seek medical advice if discomfort persists
Ingestion: Rinse mouth with water; drink water to dilute; do not induce vomiting unless advised by medical professional
Most Important Symptoms: Mechanical irritation of respiratory passages, eyes, or skin; no known specific systemic effects

Fire-Fighting Measures

Suitable Extinguishing Media: Water, foam, dry chemical, carbon dioxide
Specific Hazards Arising: Product itself is not flammable or explosive
Protective Equipment: Standard protective gear for surrounding fire; self-contained breathing apparatus if dust is present
Fire Decomposition Products: None expected; product does not contribute hazardous fumes
Advice for Firefighters: Avoid creation of dust cloud in firefighting scenarios

Accidental Release Measures

Personal Precautions: Wear dust protective mask, goggles and gloves; prevent dust formation
Environmental Precautions: Prevent product from entering drains overspill, gently collect and remove material
Cleanup Methods: Use HEPA vacuum or wet sweeping to minimize dust; avoid dry brushing
Disposal Materials: Clean-up residues collected in sealed, labeled containers for proper disposal

Handling and Storage

Handling: Use local exhaust ventilation to minimize dust; use protective clothing, gloves, goggles, and respiratory protection
Storage: Keep material in tightly sealed original packaging; store in cool, dry, well-ventilated place
Storage Incompatibilities: Not reactive with most materials; avoid moisture intrusion to prevent clumping
Safe Practices: Prevent formation of airborne dust, keep away from food and drink areas
Hygiene: Wash hands before eating, drinking, or smoking

Exposure Controls and Personal Protection

Permissible Exposure Limits: OSHA PEL for nuisance dust: total dust 15 mg/m3, respirable dust 5 mg/m3
Engineering Controls: Use process enclosures and local ventilation to keep air concentrations low
Personal Protective Equipment: Dust mask (NIOSH-approved), safety goggles, protective gloves, protective clothing
Respiratory Protection: Properly fitted particulate respirator in dusty environments
Hand Protection: Cloth or nitrile gloves for repeated contacts
Eye Protection: Safety goggles or face shield
General Safety: Change contaminated clothing and take appropriate measures for workplace cleanliness

Physical and Chemical Properties

Appearance: White powder with no odor
Odor: None
Physical State: Fine, dry, crystalline powder
pH: Neutral (aqueous suspension ~6–8)
Melting Point: > 1800°C
Boiling Point: Not relevant (sublimes before boiling)
Solubility in Water: Insoluble
Density: 3.9–4.2 g/cm3 (depending on grade)
Partition Coefficient: Not available; negligible bioaccumulation due to insolubility
Vapor Pressure: Not applicable
Flash Point: Not flammable
Other Properties: Chemically stable, does not emit hazardous fumes under normal use

Stability and Reactivity

Chemical Stability: Product does not decompose at environmental temperatures and conditions
Reactivity: Inert in most environmental and industrial settings
Hazardous Reactions: No known hazardous reactions with common substances; avoid mixing with strong reducing agents
Conditions to Avoid: Avoid high humidity for extended periods, as material may clump
Decomposition Products: At extremely high temperatures can yield titanium oxide fumes

Toxicological Information

Acute Effects: Low toxicity; inhalation may cause mechanical irritation
Chronic Effects: IARC Group 2B classification — possible human carcinogen by inhalation of fine dust
Ingestion: Not considered toxic by ingestion in standard exposures
Skin Contact: No significant adverse effects in standard industrial handling
Inhalation: High concentrations of airborne powder may cause lung overload
Other Relevant Data: No evidence of mutagenicity, teratogenicity, or developmental toxicity
Sensitization: Not a skin or respiratory sensitizer by current data

Ecological Information

Ecotoxicity: Not anticipated to be toxic to aquatic or terrestrial species due to insolubility
Persistence and Degradability: Does not degrade under typical environmental conditions
Bioaccumulation Potential: Unlikely due to very low solubility
Mobility in Soil: Forms stable, immobile particulate; not readily washed into water systems
Other Adverse Effects: No evidence of environmental hazard under expected uses

Disposal Considerations

Waste Treatment Methods: Collect and contain spills for landfill or as inert non-hazardous waste
Disposal Containers: Use sealed, labeled bags or drums for shipping to landfill
Environmental Impact: Avoid release in bulk quantities to waterways or drains
Special Considerations: For disposal beyond small quantities, consult local waste disposal authorities
Regulatory Status: Not a listed hazardous waste under US RCRA; check regional regulations

Transport Information

UN Number: Not classified as dangerous good under ADR, DOT, IMDG, IATA
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Special Precautions: Keep containers secure and protected from dust spillage during transit
Labeling Requirements: Standard shipping documentation; no specific hazard labeling required

Regulatory Information

OSHA: Considered nuisance dust; not listed as hazardous chemical
SARA Title III: Not listed
TSCA: Substance is listed and regulated in US
European Regulation: REACH registered and listed on EINECS/ELINCS inventory
Labelling in Accordance With GHS: Not classified as dangerous; some formulations or applications may trigger local requirements
Other Applicable Laws: Follows food and cosmetic safety regulations for grades intended for those end uses