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West Ujimqin Banner, Xilingol League, Inner Mongolia, China
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Product Name: Thaumatin
Chemical Family: Protein sweetener derived from Thaumatococcus daniellii berries
CAS Number: 53850-34-3
EC Number: 258-822-2
Synonyms: E957, Talin
Intended Use: Flavor modifier, sweetener for food and beverage applications
Supplier: Known producers and distributors specialize in sourcing from certified botanical suppliers in West Africa or through controlled fermentation processes.
Contact Details: Manufacturer contact information supplied on product labeling
Emergency Telephone: Provided by the supplying company for direct consultation in acute scenarios
Classification: Not classified as hazardous under GHS standards
Potential Health Effects: Inhalation of protein dust may cause mild respiratory irritation or sensitization in some exposed individuals; no recognized carcinogenicity or mutagenicity
Signal Word: None
Pictograms: None required
Precautionary Statements: Avoid creating or breathing dust; avoid contact with eyes; maintain proper workplace hygiene in handling
Component: Thaumatin
Concentration: Typical preparations contain >98% thaumatin by weight
Impurities/Additives: Negligible traces of plant residues, water or buffer salts from extraction process
Molecular Formula: C122H196O42N32S7
Molecular Weight: Approximately 22,000–25,000 g/mol
Inhalation: Move affected person to fresh air; provide water to rinse mouth; medical attention recommended if cough or irritation lingers
Skin Contact: Wash exposed skin with soap and water for at least 15 minutes; remove contaminated clothing; usually not irritating
Eye Contact: Rinse thoroughly with clean water for at least 10 minutes; seek medical advice if redness or discomfort persists
Ingestion: Rinse mouth and drink water; given generally recognized as safe (GRAS) status, no adverse effects expected at common food-use levels; seek medical help if unusual symptoms occur
Advice for Doctor: Treat symptomatically; protein allergen response rare but possible in heavily exposed individuals
Suitable Extinguishing Media: Foam, carbon dioxide, dry powder, water spray
Unsuitable Media: Direct high-pressure water jets (may spread dust)
Specific Hazards: Combustible dust at high concentrations; can form explosive mixtures with air in powder form
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides possible in large-scale fire
Special Protective Equipment: Firefighters use self-contained breathing apparatus and protective suit
Advice: Avoid inhaling combustion gases; evacuate area if large-scale dust fire is suspected
Personal Precautions: Wear suitable dust mask and gloves to avoid inhalation and direct contact
Environmental Precautions: Prevent release into drains, waterways, or soil in large quantities; generally low environmental risk in small spills
Methods for Clean-Up: Sweep or vacuum up material without creating a dust cloud; place into properly labeled containers; ventilate area
Decontamination: Wash area with water once bulk is removed
Handling: Handle in well-ventilated environment; minimize dust creation; avoid contact with strong oxidizers; wear protective clothing and mask if handling bulk powder
Storage: Keep in tightly sealed original containers; store in cool, dry, well-ventilated place away from moisture and strong odors; avoid exposure to direct sunlight, heat, or humidity
Incompatibilities: Strong acids, bases, and oxidizers
Packaging Materials: Food-grade, tightly sealed containers made of plastic or metal; avoid permeable packaging materials
Occupational Exposure Limits: No official exposure limits assigned
Engineering Controls: Use local exhaust ventilation or dust extraction equipment in processing areas
Respiratory Protection: Use N95-type mask or equivalent during powder handling activities
Eye Protection: Safety glasses with side shields
Skin Protection: Impermeable gloves and laboratory or light industry workwear
Hygiene Measures: Wash hands after handling; avoid eating, drinking, or smoking in work areas; launder work clothes regularly
Appearance: White to off-white, free-flowing powder
Odor: Mild to neutral, may carry slight sweet aroma
Odor Threshold: Not applicable
pH (5% w/v solution): 5–7
Melting Point: Degrades on heating, no sharp melting point
Boiling Point: Not applicable
Flash Point: Not established for proteinaceous substances
Flammability: Fine powder may be combustible at high dust concentrations
Explosive Properties: Dust explosion risk under certain industrial processing conditions
Density: Approx. 0.35–0.50 g/cm3 (bulk density)
Solubility: Freely soluble in water; practically insoluble in most organic solvents
Partition Coefficient (n-octanol/water): Not relevant for large biomolecules
Viscosity: Not relevant
Decomposition Temperature: >120°C
Chemical Stability: Stable under recommended storage conditions; prone to denaturation or degradation by extreme heat or pH
Reactivity: Not reactive under normal use; sensitive to strong oxidizers and acids
Thermal Decomposition: Produces carbon dioxide, carbon monoxide, traces of nitrogen or sulfur oxides
Conditions to Avoid: High temperature, high humidity, exposure to strong chemical agents, sources of ignition
Incompatible Materials: Potent acids, bases, oxidizers
Hazardous Polymerization: Does not occur
Acute Toxicity: Not toxic at dietary levels; LD50 (oral, rat) >10 g/kg
Chronic Effects: Regular consumption at approved levels in food shows no adverse effects in independent safety studies
Skin Irritation: Not irritating under common exposure circumstances
Eye Irritation: May cause mild transient irritation
Sensitization: Potential for allergenicity is low but not absent; occupational exposure rarely induces respiratory sensitization
Mutagenicity: No evidence from available animal or in vitro tests
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA, or EU CLP
Reproductive Toxicity: No adverse effects reported in multi-generation studies
Ecotoxicity: No significant toxicity to aquatic life or terrestrial organisms has been recorded
Persistence and Degradability: Biodegradable protein; breaks down through microbial activity
Bioaccumulation Potential: Low; rapid biodegradation in soil and water
Mobility in Soil: Water-soluble; little potential for soil binding or accumulation
Other Adverse Effects: No known significant environmental impact at usage levels
Waste Treatment Methods: Small quantities may be diluted and disposed of in general waste following local regulations
Disposal of Packaging: Rinse and reuse or recycle containers where permitted; follow local guidelines for recovery or landfill
Special Handling: For larger volumes, follow advice from a waste disposal contractor familiar with food or proteinaceous waste
Environmental Precautions: Avoid disposal to surface water or storm drains in bulk; sweep up solid material to prevent dust release during transport to waste facility
UN Number: Not classified as dangerous for transport
Proper Shipping Name: Thaumatin, not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not considered hazardous to the environment
Special Precautions: Protect from moisture and direct sunlight during transit; ensure packaging integrity
Transport by Land/Sea/Air: Not subject to ADR, IMDG, IATA restrictions
Labelling: No hazard labeling required under OSHA, EU CLP or GHS
Occupational Exposure Standards: None established for thaumatin
Inventory Status: Listed on US TSCA, EU REACH, and other major chemical inventories
Food Safety Approvals: Approved as food additive E957 in EU, GRAS in US, accepted in Japan and many other countries
Restrictions: Use must meet GMP/food grade standards; only use for intended application in food or flavor
Other Laws: Compliance with regional food laws and export control provisions may apply for large shipments
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
