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Product Name: Synephrine Hydrochloride
Chemical Formula: C9H14NO2 · HCl
Synonyms: 4-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride, Oxedrine hydrochloride
CAS Number: 5985-28-4
Recommended Use: Research, supplement manufacture, reference standard
Manufacturer: Information available from the supplier
Contact Information: Emergency phone numbers provided by supplier
Classification: Irritant, harmful if swallowed
Signal Word: Warning
Hazard Statements: May cause irritation to eyes, skin, and respiratory tract. Harmful if swallowed. Possible risk of cardiovascular effects with exposure.
Pictograms: Exclamation mark for skin/eye/respiratory irritation
Precautionary Statements: Avoid breathing dust, avoid direct contact, use protective gear, wash hands thoroughly
Chemical Name: Synephrine Hydrochloride
Concentration: >98% pure
Other Components: Inert manufacturing residues may be present at trace levels. No significant impurities contributing to hazard classification identified.
Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical attention if symptoms occur
Skin Contact: Remove contaminated clothing, rinse affected area with plenty of water, seek help for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, seek attention if irritation continues
Ingestion: Rinse mouth, offer water, do not induce vomiting unless directed by medical personnel, get medical help if unwell
Most Important Symptoms: Irritation, headache, dizziness, possible rapid heartbeat in sensitive individuals
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Specific Hazards: Combustible dust may form explosive mixtures with air. Hazardous gases like hydrogen chloride may develop in fire.
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective clothing
Advice for Firefighters: Avoid inhaling smoke and fumes, use water to cool unopened containers exposed to fire
Personal Precautions: Keep unprotected people away, don gloves and eye protection, ventilate area
Environmental Precautions: Prevent powder from entering waterways, drains, or soil
Methods for Cleanup: Use HEPA-filtered vacuum or wet sweeping to collect, avoid stirring up dust, place residue into appropriate containers for disposal
Spill Reporting: Notify authorities if significant quantities involve environment
Handling: Practice good laboratory hygiene, avoid creating dust, avoid breathing dust or mist, ensure local exhaust ventilation
Storage Conditions: Keep in tightly closed container, store in a cool, dry, well-ventilated place away from moisture, strong acids, and oxidizers
Incompatibilities: Strong acids, strong oxidizing agents, strong bases, ensure segregation from food and drink
Control Parameters: No occupational exposure limits established specifically for synephrine hydrochloride
Engineering Controls: Use fume hood or local exhaust ventilation to minimize exposure
Protection: Nitrile gloves, lab coat, chemical safety goggles, dust mask or respirator in poorly ventilated conditions
Hygiene Measures: Wash skin thoroughly after handling, remove contaminated clothing before leaving work area, never eat or drink in handling area
Appearance: White or off-white crystalline powder
Odor: Odorless or mild chemical odor
Molecular Weight: 211.68 g/mol
Melting Point: Approximately 187–189°C
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, slightly soluble in ethanol
pH: 4–6 (in 15% solution)
Vapor Pressure: Not applicable
Partition Coefficient: Data not available
Flash Point: No information due to high decomposition temperature
Chemical Stability: Stable under recommended storage conditions
Reactivity: No hazardous reactions expected under normal use
Conditions to Avoid: Excess heat, humidity, exposure to strong oxidizers or acids
Incompatible Materials: Strong oxidizing agents, reducing agents, alkalis, acids
Hazardous Decomposition: Hydrogen chloride, carbon monoxide, carbon dioxide, nitrogen oxides if heated to decomposition
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Irritation, nausea, headache, increased heart rate, hypertension in sensitive individuals
Acute Toxicity Data: Reference animal LD50 (oral, rat) ~200–500 mg/kg
Chronic Effects: No clear data on long-term exposure, misuse may cause disturbances of the cardiovascular system
Other Hazards: Allergic response in susceptible persons
Toxicity to Aquatic Life: No specific data, caution applied due to possibility of toxicity to aquatic organisms
Persistence/Degradability: Not readily degradable, data incomplete
Bioaccumulation Potential: Not expected based on molecular structure
Mobility in Soil: Soluble in water so may migrate through soil if released
Other Adverse Effects: Prevent substance from entering waterways to avoid potential environmental impact
Disposal Methods: Incineration in approved facility or landfill in line with local regulations
Container: Triple rinse and dispose of containers safely as chemical waste
Precautions: Do not allow large volumes to reach sewage system or waterways, consult regulatory agencies for specific rules
UN Number: Not assigned for this substance
Proper Shipping Name: Chemical, NOS (not otherwise specified)
Hazard Class: Not regulated for transport in most jurisdictions
Packing Group: Not assigned or not classified as dangerous
Special Precautions: Secure containers to prevent leaks, avoid extremes of temperature or humidity during transport
Global Inventories: Listed in some chemical inventories (consult regional regulations)
SARA 313 (USA): Not subject
California Proposition 65: Not listed
REACH Registration (EU): Not required for most research or laboratory uses, always refer to specific regulatory status
Labeling Requirements: Compliant with OSHA, GHS, and other relevant standards
Precautionary Measures: Label all containers clearly, train all users in safe handling, maintain available safety data for reference
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
