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Product Name: Sulfadimidine Sodium
Chemical Formula: C12H13N4NaO2S
CAS Number: 1981-58-4
Synonyms: Sulfamethazine Sodium, Sodium Sulfadimidine
Recommended Use: Antibacterial agent for veterinary and sometimes human application
Supplier: Refer to label specifics or purchasing department for vendor name and emergency phone
Emergency Contact Number: Local emergency services or company safety officer
Classification: Harmful if swallowed, skin and eye irritant
Signal Word: Warning
Hazard Statements: May cause allergic skin reaction; possible risk of eye damage; may affect the kidneys and liver through repeated exposure
Pictograms: Exclamation mark, Health hazard symbol
Precautionary Statements: Wash hands after handling. Wear protective gloves and eye protection. Avoid inhalation and ingestion. Seek medical advice if symptoms occur.
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Chemical Name: Sulfadimidine Sodium
Concentration: Typically ≥98% pure; remaining content includes moisture and possible trace impurities
Impurities: May contain very low levels of residual synthesis byproducts
EC Number: 217-993-3
Molecular Weight: 300.31 g/mol
Inhalation: Move affected person to fresh air. Seek attention if symptoms like coughing or wheezing develop.
Skin Contact: Remove contaminated clothing and flush skin fully with plenty of water. Get medical help for irritation or rash.
Eye Contact: Rinse opened eye slowly and gently with water for 15 minutes or longer. Call physician for persistent discomfort.
Ingestion: Rinse mouth with water, do not induce vomiting unless instructed by medical personnel. Call a poison control center or physician.
Notes to Doctor: Treat symptoms. Monitor for delayed effects on kidney and liver.
Suitable Extinguishing Media: Use carbon dioxide, dry powder, alcohol-resistant foam, or water spray.
Unsuitable Media: Strong water jets may spread the chemical.
Fire Hazards: Product may produce toxic vapors including nitrogen oxides and sulfur oxides when burned.
Protection for Firefighters: Full protective gear and self-contained breathing apparatus required.
Special Procedures: Prevent run-off from entering drains and water sources.
Combustion Products: Carbon dioxide, carbon monoxide, nitrogen oxides, sulfur oxides
Personal Precautions: Wear gloves, lab coat, eye and respiratory protection. Avoid generating dust. Evacuate area if necessary.
Environmental Precautions: Prevent spillage from entering drains, surface water, or soil. Notify relevant authorities if contamination occurs.
Cleanup Procedures: Scoop or sweep up spilled material without raising dust, place in suitable container for disposal. Clean area thoroughly.
Decontamination: Wash spill area with plenty of water. Dispose of cleaning water as chemical waste.
Handling: Avoid contact with skin, eyes, and clothing. Use in a well-ventilated area or fume hood. Wear proper PPE. Wash hands before eating or drinking.
Storage: Store in a tightly closed, labeled container, protected from direct sunlight, heat, and moisture. Maintain at room temperature; avoid freezing or overheating.
Incompatibilities: Keep away from oxidizing materials and strong acids.
Special Requirements: Ensure containers are kept off the floor and inspect regularly for damage.
Engineering Controls: Use local exhaust ventilation. Work inside chemical fume hood if dust or fumes might be generated.
Occupational Exposure Limits: No established limit for Sulfadimidine Sodium; maintain lowest possible exposure.
Personal Protective Equipment: Gloves (nitrile or latex), chemical safety goggles, long-sleeved lab coat, dust mask or approved respirator.
Hygiene Measures: Avoid eating, smoking, or drinking while handling. Wash hands after use and before breaks. Change contaminated clothing promptly.
Appearance: White to off-white crystalline powder
Odor: Odorless
pH: 9.0–10.5 (for 10% solution in water)
Melting Point: 198–200°C
Solubility: Freely soluble in water; slightly soluble in ethanol
Boiling Point: Data not available (decomposes before boiling)
Relative Density: 1.64 g/cm³
Partition Coefficient: Log Kow: -0.39 (estimated)
Vapor Pressure: Negligible at room temperature
Flash Point: Not flammable under standard conditions
Stability: Stable under recommended storage conditions; avoid excess heat and humidity.
Reactivity: Chemically inactive at room temperature; can react with strong oxidizers.
Incompatible Materials: Strong acids, strong bases, oxidizing agents.
Hazardous Decomposition: Produces toxic gases such as nitrogen oxides, sulfur oxides on thermal decomposition.
Polymerization: Does not occur.
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: Oral LD50 (rat): 1550–3400 mg/kg
Chronic Toxicity: Prolonged exposure can cause allergic reactions, kidney or liver impairment, and blood disorders.
Irritation: May cause redness and irritation to skin and eyes.
Sensitization: May cause allergic skin reactions in susceptible individuals.
Reproductive Effects: Not classified as a reproductive toxin.
Carcinogenicity: Not listed by IARC, NTP, or OSHA.
Mutagenicity: No data from long-term studies; caution advised.
Environmental Toxicity: Harmful to aquatic life at high concentrations.
Mobility: Readily soluble in water, can move through soil and water systems.
Persistence: Does not biodegrade rapidly in the environment.
Bioaccumulation: Low potential to bioaccumulate.
Aquatic Effects: LC50 for fish (96h): >100 mg/L (low acute toxicity); may promote antibiotic resistance in exposed microbial communities.
Other Effects: Can disrupt natural microbial flora if released in large amounts.
Disposal Methods: Incinerate in a chemical incinerator operated by permitted facilities. Do not dispose into surface water, soil, or sewage system.
Container Disposal: Empty containers should be triple rinsed, then disposed according to local regulations as chemical waste.
Special Precautions: All disposal must conform to federal, state, and local environmental regulations. Minimize environmental exposure.
Waste Codes: Contact local regulatory authorities for applicable codes.
UN Number: Not classified as a dangerous good under international transport regulations.
Proper Shipping Name: Sulfadimidine Sodium
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Marine Pollutant: No
Special Transport Precautions: Secure containers to prevent breakage, ensure upright positioning. Prevent contamination of food or feedstuffs during transit.
GHS Classification: Skin Sensitizer (Category 1); Eye Irritant (Category 2A)
Regulatory Status: Subject to local chemical safety regulations; not listed as controlled under the Controlled Substances Act.
Inventory Listings: Listed on TSCA (US), EINECS (EU), DSL (Canada).
Label Requirements: Clearly display hazards, handling and emergency instructions per local legislation.
SARA Title III: Not subject to Section 313 reporting.
Other Regulations: Refer to residue and use restrictions by FDA (USA) and EMA (EU) for veterinary pharmaceuticals.
