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Product Name: Sucralose
Chemical Name: 1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside
Chemical Formula: C12H19Cl3O8
CAS Number: 56038-13-2
Synonyms: Trichlorogalactosucrose, E955
Use: Artificial sweetener for food and beverages, tabletop sweetener, pharmaceutical preparations, cosmetic and oral care products
Manufacturer/Supplier Contact: Refer to supplier documents for phone numbers and addresses
Classification: Not classified as hazardous according to OSHA or EU regulation
GHS Label Elements: No symbol or signal word required
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Health Hazards: Dust irritation possible for eyes, skin, and respiratory tract in sensitive individuals
Environmental Hazards: Potential risk to aquatic life if large quantities released
Sucralose (Active Ingredient): Content at least 98% by weight
Impurities: Chlorinated derivatives & trace carbohydrates; typically at less than 2%
Other Ingredients: None typically present above 1% by weight
General Guidance: Seek fresh air and medical advice if symptoms develop
Inhalation: Move to fresh air, rinse mouth, get medical help if cough or breathing trouble starts
Skin Contact: Wash with running water and soap, remove contaminated clothing, seek help if irritation persists
Eye Contact: Rinse with water for several minutes, consult a medical provider for persistent irritation
Ingestion: Rinse mouth, drink water, call poison control or a physician for guidance on symptoms
Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Special Hazards: Burning may produce hydrogen chloride and carbon oxides, avoid inhaling smoke
Firefighting Equipment: Self-contained breathing apparatus and full protective gear recommended
Fire Precautions: Remove containers from fire area if safe, cool surfaces with water mist
Personal Protection: Wear dust mask, safety glasses, gloves
Spill Response: Ventilate area, avoid dust, sweep up and collect in appropriate container for disposal
Cleanup Method: Use wet methods to avoid dust, wash residue with water
Environmental Precautions: Prevent entry into sewers, waterways
Handling: Avoid generating airborne dust, wear appropriate PPE, wash hands after handling
Storage: Keep in tightly closed container in a cool, dry, well-ventilated area, protect from strong oxidizing agents and direct sunlight
Incompatibilities: Strong acids, strong bases, oxidizers
Special Instructions: Keep away from food and feed, avoid contamination
Engineering Controls: Use local exhaust ventilation for dust control in bulk handling
Personal Protection: Safety glasses, dust mask, gloves, lab coat
Exposure Limits: No OSHA/ACGIH limits established for sucralose
Hygiene Measures: Wash hands before eating, keep working clothes separate, launder regularly
Appearance: White to off-white crystalline powder or granules
Odor: Odorless
Taste: Very sweet (about 600 times sweeter than sucrose)
Solubility: Soluble in water, slightly soluble in ethanol
pH of Solution: 5–8 (1% aqueous solution)
Molecular Weight: 397.64 g/mol
Melting Point: Decomposes >125°C (heat sensitive)
Boiling Point: Decomposes before boiling
Vapor Pressure: Not applicable
Density: 1.375 g/cm3 (bulk density varies with granulation)
Other Data: Non-volatile, stable in dry conditions
Stability: Stable under recommended handling and storage conditions
Conditions to Avoid: Excess heat, exposure to acids, bases, or strong oxidizers
Incompatible Materials: Strong acids, bases, oxidizing agents
Decomposition Products: Hydrochloric acid, carbon monoxide, carbon dioxide, possible traces of chlorinated organic compounds
Hazardous Reactions: No hazardous polymerization expected
Acute Toxicity: Sucralose tested in rats and mice at high doses without mortality; rat oral LD50 above 10 g/kg
Chronic Effects: Long-term animal studies reported no significant toxicity at typical exposure levels
Irritation: Not an irritant to skin or eyes under normal handling
Sensitization: Not recognized as a sensitizer
Carcinogenicity: Not listed as carcinogen by IARC, NTP, ACGIH, or OSHA
Reproductive Effects: Animal studies did not show teratogenic or reproductive toxic effects
Additional Information: Not absorbed or metabolized to any significant extent by the body; most excreted unchanged with minimal bioaccumulation
Ecotoxicity: Moderate persistence, low acute toxicity to aquatic organisms at typical levels
Mobility: Mobile in water, unlikely to bioaccumulate or bind strongly to sediment
Persistence/Degradability: Resistant to microbial degradation in the environment; potential for persistence
Bioaccumulation: Expected to have low potential for accumulation in organisms
Other Data: Chronic exposure in aquatic setting may require further long-term scrutiny as wastewater treatment may not fully remove the compound; monitoring in surface waters has become part of environmental protocols in some regions
Waste Treatment: Dispose of in accordance with local, regional, and national regulations
Recommended Methods: Small quantities may go to landfill; large amounts treated as chemical waste
Container Disposal: Completely empty containers preferred for local recycling or disposal; triple-rinse before recycling
Precautions: Avoid release to environment; never flush large quantities into drains
UN Number: Not regulated as a hazardous material
Transport Hazard Class: None assigned
Packaging Requirements: Use containers that prevent moisture ingress; label if mixed with other ingredients
Marine Pollutant: Not regulated
Special Precautions: Protect from physical damage and spillage during transport, keep away from incompatible materials
European Union: Authorized food additive (E955); not classified as hazardous under CLP Regulation
United States: FDA-approved food additive, not regulated as hazardous under TSCA, not subject to SARA Title III, CERCLA, RCRA
Canada: Approved as food additive, not controlled under WHMIS
Other: Accepted by Codex Alimentarius, included in national food additive lists in many countries
Labeling Requirements: No special hazard labeling for handling or transport
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
