West Ujimqin Banner, Xilingol League, Inner Mongolia, China sales9@alchemist-chem.com 1531585804@qq.com
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Stevia: A Comprehensive Look at Nature’s Sweet Leaf

Historical Development of Stevia

Long before supermarkets stocked zero-calorie sweeteners, the Guaraní people in Paraguay and Brazil were plucking stevia leaves to sweeten teas and medicines. They called it “ka’a he’ê,” or “sweet herb.” Centuries later, in the late 19th century, European botanists finally classified stevia (Stevia rebaudiana Bertoni). Early use focused not just on its sweetness, but on how it could replace sugar in daily life—important for people without easy access to refined sugar. Industrial interest in the plant took off during World War II, when sugar shortages forced Japan to find alternatives. Soon after, Japanese researchers figured out how to isolate pure steviol glycosides, launching the first commercial stevia-based sweeteners. Western markets caught on several decades later, propelled by demand for fewer empty calories and consumer skepticism toward artificial additives.

Product Overview

Stevia stands out as a natural, plant-derived substitute for sugar. It delivers intense sweetness—about two to four hundred times sweeter than table sugar—without contributing calories. Grocery shelves now carry stevia in powder, tablet, and liquid forms, which stem from drying, extracting, and purifying compounds called steviol glycosides from the leaves. Some producers blend stevia extracts with other bulking agents to mimic sugar’s texture for baking. The ingredient list often includes names like Reb A (rebaudioside A), Reb M, or simply “stevia leaf extract.” Consumers looking for clean labels gravitate toward products that tout minimal processing and non-GMO sourcing.

Physical & Chemical Properties

Stevia extracts rely on steviol glycosides, especially rebaudioside A and stevioside, to deliver their signature intense sweetness. These white, odorless powders exhibit remarkable heat and pH stability, keeping their taste in recipes from coffee to cookies. Unlike sugar, steviol glycosides dissolve easily in water but never feed yeast, so bread doesn’t rise with stevia-based formulations. The glycosides themselves resist caramelization and browning, which can stump bakers trying to mimic golden crusts or toffee-like chew. Chemically, each steviol glycoside molecule has a steviol backbone linked to glucose or rhamnose residues. This structure affects how quickly sweetness appears and fades on the tongue, sometimes leaving a faint herbal or licorice aftertaste.

Technical Specifications & Labeling

Every bag or packet of commercial stevia must break down its ingredients for clear labeling. Manufacturers typically specify steviol glycoside content, with high-purity stevia extracts listing over 95% of these sweet molecules. Labeling laws in the United States demand explicit naming—“stevia leaf extract” or separate listings for each rebaudioside or stevioside content. The food industry watches these standards closely, since regulatory limits on solvent residues and heavy metals shape sourcing and manufacturing. Most labels also feature certifications for organic, non-GMO, or allergen-free claims, often highlighted to attract health-focused customers.

Preparation Method

Stevia starts on sprawling farms in Paraguay, China, or Kenya, where workers harvest leaves at peak sweetness. After drying, the leaves move to extraction tanks filled with hot water or food-grade alcohol. That liquid, brimming with steviol glycosides, gets filtered and concentrated. The resulting extract undergoes purification steps—often passing through resin columns and gentle crystallization—to draw out the purest, sweetest compounds. Each step strips away bitter co-extracts and plant solids. Producers then dry or spray the extract into powder or dissolve it into syrups. Some processes add a final “polishing” to remove any lingering off-tastes, fine-tuning the sweetness before packaging.

Chemical Reactions & Modifications

Raw extracts often possess a lingering bitterness alongside sweetness, so scientists tweak chemical structures. Enzymatic modification, for instance, attaches new sugar units to steviol glycosides, sometimes yielding Reb D or Reb M, which taste smoother and less herbal. Others hydrogenate or methylate the glycosides, chasing the ever-elusive cane sugar profile. Some companies experiment with fermentation, teaching yeast or bacteria to churn out rare glycosides with fewer byproducts and a smaller environmental footprint. Converting crude stevia into desirable compounds turns a lot of research dollars, since consumer demand leans toward sugar-like taste and clean labeling.

Synonyms & Product Names

Stevia products come under plenty of labels and nicknames. Besides “stevia leaf extract,” shelves might feature “steviol glycosides,” “rebaudioside A,” or “natural sweetener.” Some health food brands market it as “green sugar” or simply “sweetleaf.” Product lines often get creative: Sun Crystals, Stevia In The Raw, Pure Via, Truvia, and SweetLeaf all rely on stevia extracts, though formulas may pair with erythritol, inulin, or dextrose for improved texture and taste. Ingredient disclosures list exact glycoside percentages when purity takes center stage in marketing.

Safety & Operational Standards

Regulatory agencies like the U.S. Food and Drug Administration and the European Food Safety Authority have placed steviol glycosides on safe lists after years of toxicity and metabolic research. High-purity stevia extracts have earned “Generally Recognized As Safe” (GRAS) status in the U.S., nudging manufacturers to meet rigid testing for pathogens, pesticide residues, and heavy metals. Food factories monitor for microbial limits and maintain traceability of every batch, from field to grocery shelf. Producers audit suppliers and run third-party lab tests before approving stevia extracts for food use. Professional groups, like the Joint FAO/WHO Expert Committee on Food Additives, set acceptable daily intake benchmarks—roughly 4 mg of steviol equivalents per kilogram of body weight.

Application Area

Stevia shows up in more places than soda and tabletop sweeteners. Beverage industry giants replace a chunk of sugar with stevia to drop calorie counts while keeping sweetness on par with traditional formulations. Yogurt makers, jam producers, and cereal companies see profit in “reduced sugar” claims. Home cooks blend stevia into coffee, oatmeal, salad dressings, and desserts. Even toothpaste and mouthwash brands capitalize on the non-cariogenic nature of stevia—oral bacteria can’t ferment steviol glycosides, so cavities find little encouragement. Pharmaceutical preparations, especially those targeting diabetics, make use of stevia’s low glycemic impact.

Research & Development

Companies and universities chase new varieties of Stevia rebaudiana that produce sweeter leaves with less bitterness. Efforts span genetic selection, advanced breeding, and even CRISPR tweaks to boost yields. Ingredient scientists refine isolation and modification, always reaching for natural-tasting glycosides. Some startups use microbial fermentation to craft rare glycosides, promising sustainability and flavor control. R&D budgets focus on improving solubility, masking off-notes, and blending with bulk sweeteners that mimic sugar’s body and browning behavior. Taste panels and consumer surveys drive decisions, with a clear shift toward clean, transparent labeling and eco-friendly processing.

Toxicity Research

Researchers have combed through stevia’s effects in lab animals and human volunteers, tracking blood sugar, liver enzymes, allergic responses, and long-term metabolic changes. Large reviews published by EFSA and JECFA confirm that steviol glycosides don’t cause cancer, reproductive issues, or DNA mutations at reasonable intake amounts. Human trials record stable insulin responses and little to no gastrointestinal distress, even in sensitive populations. The hype around “natural” ingredients always calls for vigilance, but the current consensus holds strong: high-purity stevia doesn’t pose health risks at expected consumption rates.

Future Prospects

Global sugar reduction trends and government health initiatives keep stevia’s prospects bright. Ingredient companies race to unlock proprietary strains and formulations that satisfy both label-conscious buyers and old-school flavor traditionalists. New extraction and modification techniques aim to cut costs and boost flavor, helping stevia undercut both synthetic and plant-derived competitors. Pharmaceutical and nutraceutical segments see promise in stevia’s possible antioxidant and anti-inflammatory roles—early research teases therapeutic effects beyond sweetness alone. As consumers grow wary of lab-made sweeteners and demand better-tasting “natural” options, stevia looks ready to remain a fixture in the evolving pantry.




What is Stevia and how is it made?

Getting to Know Stevia

Stevia comes from the leaves of the Stevia rebaudiana plant, a small green herb native to South America. Indigenous people have used these leaves to sweeten foods and drinks for hundreds of years, long before anyone tried to put it in a packet. People who want less sugar in their diet start looking for something that tastes sweet but doesn’t load up the calories. Stevia answers that call. Just a pinch of this plant’s extract can make coffee or tea taste just as sweet as regular sugar.

Extracting the Sweetness

Farmers grow stevia in warm climates, harvest the leaves, then dry and crush them. Getting the sweet stuff out doesn’t take a science lab, but food companies want the purest taste. They soak the dried leaves in water, a lot like making a strong herbal tea. From there, they filter out the leafy bits and concentrate the liquid. The goal is to collect chemicals called steviol glycosides. These naturally sweet compounds don’t affect blood sugar and don’t spike insulin, which matters for people worried about diabetes.

Purifying stevia extract further removes any plant taste or bitterness, turning it into a fine white powder or liquid drops. Grocery stores sell it mixed with other ingredients to measure and pour more easily. Most times, a serving of table-top stevia contains a tiny bit of stevia extract and a lot more bulking agents like erythritol, inulin, or maltodextrin. Without these, you’d never be able to scoop or pour such a tiny serving.

Why Stevia Catches Attention

Sugar overload keeps making headlines in health news. More kids and adults face weight issues, heart problems, and type 2 diabetes. Many people have a sweet tooth but want to skip the health risks. Stevia offers a calorie-free option with a taste close to sugar and doesn’t raise blood sugar. Research backs up that it’s safe for most people in normal amounts. The World Health Organization and FDA both agree on this.

Some Challenges to Sort Out

A lot of folks try stevia and complain about a slightly bitter or licorice-like taste. Chemical companies keep tweaking the way they extract and purify stevia to fix this. Not every stevia blend on the market tastes the same, so some trial and error might be part of making the switch. People with sensitive stomachs sometimes notice that sugar substitutes, especially blended products, upset their digestive system. Natural doesn’t always mean everyone can tolerate it.

Better Choices for Sweetness

People who want to reduce sugar usually get the best luck by starting with small swaps and reading food labels carefully. If one stevia brand tastes off, another may work better. Alongside stevia, other plant-based sweeteners like monk fruit or allulose are popping up on store shelves. Some health experts remind folks that sweeteners, even the natural ones, don’t solve cravings. They suggest retraining taste buds over time.

At the end of the day, learning about the origins of what we eat and drink helps everyone make smarter decisions. Stevia started out as a wild herb and now sweetens dishes around the world, crossing the gap from old herbal teas to modern sugar-free sodas.

Is Stevia safe to consume?

Navigating the Sweetener Dilemma

Everywhere you look, food and drink come loaded with sugar. Escaping sweetened foods feels like running an obstacle course. Turning to sugar substitutes seems like an easy fix. I know plenty of people who swap cane sugar for something lighter on the calorie load. Stevia keeps popping up on ingredient lists. But what are we really putting in our coffee when we rip open a green-and-white packet?

Behind The Leaf: What is Stevia?

Stevia comes from the leaves of a plant called Stevia rebaudiana, native to South America. Indigenous communities there used the leaves to add sweetness to teas and medicines long before food science labs figured out how to extract and powder the sweet stuff. Today, what most of us pour into our mug isn’t the raw leaf—it’s usually rebaudioside A, a refined extract. That’s why the taste often feels sharper or can leave that unmistakable bitter note.

Science and Health: What Research Actually Shows

I’ve paid close attention to studies around new sweeteners. Stevia stands out because it dodges much of the controversy that surrounds artificial sweeteners like aspartame or sucralose. Experts at the U.S. Food and Drug Administration recognize certain purified stevia extracts as generally safe to eat in normal amounts. The World Health Organization and the European Food Safety Authority echo this, setting daily intake guidelines far above what most people would reach.

Research on stevia’s effect on blood sugar delivers encouraging results, especially for people dealing with diabetes or prediabetes. Stevia doesn’t spike blood sugar and won’t send insulin levels surging. A few small clinical trials show people using stevia actually had slightly lower blood pressure—though not always enough to count as a reliable fix for hypertension.

Gut Reactions and Digestive Considerations

I’ve heard complaints about mild digestive upset after a stevia-sweetened snack. Turns out this isn’t all in anyone's head. As the gut processes the less digestible parts of stevia, some people run into gas or looser stools. Still, these side effects seem rare and mild unless someone’s really going overboard with use. I recommend listening to your own body—if stevia brings on discomfort, there’s nothing wrong with passing it by.

Long-Term Safety and Common Sense

Long-term data on heavy stevia use remains pretty thin. But there isn’t much evidence hinting at serious risk with normal use. Some folks worry about fertility, cancer, or hormonal disruption, but laboratory results don’t back up these fears for commercial stevia extracts. That said, whole stevia leaves and crude extracts face tighter controls; they haven’t cleared enough safety hurdles for every agency.

Walking the Grocery Store Aisle

Choosing how to sweeten your food is personal. If someone is ditching extra sugar for weight management, diabetes, or just prefers the taste, stevia isn’t a magic bullet, but it’s better than piling on refined sugar all day. Pairing stevia with a diet rich in whole foods and keeping processed snacks to a minimum gives you the best shot at health. Making choices with eyes open—checking labels, reading up on new ingredients—goes a lot further than grabbing the latest thing at eye level.

Does Stevia have any side effects?

Sifting Through the Hype

People want sweet flavors without all the sugar. Stevia stepped in and grabbed a lot of attention. This plant-based sweetener promises zero calories and a taste that works in coffee, baking, and more. Supermarkets stock it everywhere. Dietitians tout its benefits for weight loss and diabetes. But scratch beneath the cheerful leaf logo and a simple question lingers: does Stevia bring along side effects?

The Science Behind Stevia Use

Stevia comes from the leaves of Stevia rebaudiana, a plant used by Indigenous communities in Paraguay for centuries. The sweet compounds — stevioside and rebaudioside A — can be hundreds of times sweeter than table sugar. The U.S. Food and Drug Administration (FDA) approved purified stevia extracts as generally recognized as safe (GRAS) for food use. Health Canada and the European Food Safety Authority share similar guidance. My own pantry holds a box of single-serve packets, picked up when blood sugar started ticking upward. Nutrition clinics hand out stevia samples to patients every week as an alternative to table sugar or artificial sweeteners.

Reported Side Effects: What People Notice

With all those approvals, it gets easy to assume stevia brings nothing but sweetness. Dig around the scientific journals and some interesting patterns appear. Mild digestive complaints pop up most often: some people deal with bloating or a mild stomach ache after using stevia in large amounts. I know a few folks in my running group who swapped regular sodas for stevia-based drinks, only to start noticing gas and grumbling bellies by afternoon. Not everyone gets these symptoms, but gut bacteria seem to fight with unfamiliar new compounds.

Another topic: blood pressure and blood sugar. Research points to stevia reducing blood pressure by a few points—helpful for most, but a problem for someone already prone to dizziness or on medication for low blood pressure. Heavy stevia use might nudge blood sugar down, helpful for people with diabetes but risky if paired with medications that also lower glucose.

Allergy and Individual Differences

Allergic reactions to stevia rarely show up, but they're possible. Someone sensitive to plants in the Asteraceae family—like ragweed, daisies, or marigolds—could react to stevia too. In nearly two decades chatting with people about sweeteners, I've heard just a couple of cases where a rash or mild swelling appeared, and both faded after switching to a different product. Still, it's worth checking ingredient lists and watching for any new symptoms with a change in diet.

The Bigger Picture of Health

No sweetener solves root causes of poor eating. It’s easy to sprinkle stevia into morning oatmeal and think the job’s done. Diet diversity, lots of fiber, quality carbs, enough protein—these matter far more for health than chasing a “natural” sugar substitute alone. Homemade iced tea tastes just as good when lightly sweetened or even left unsweetened, especially once taste buds adapt.

For anyone unsure, start slow and pay attention to your body’s response. If side effects show up, switch things up—try using less, or simply choose whole foods with naturally-occurring sugars. No sweetener erases the impact of ultra-processed snacks and drinks.

Health advice has to come from trustworthy sources. Peer-reviewed studies offer some peace of mind, but nothing beats listening to your own history and symptoms. Until new research finds clear proof of long-term harm, stevia plays a small, sweet role for people seeking options beyond sugar.

How does Stevia compare to sugar in terms of taste and calories?

The Sweetness Factor

Anyone who’s reached for a tiny green Stevia packet at a coffee shop has probably wondered if it can really replace the sweetness of regular sugar. Grown mostly in South America, Stevia rebaudiana delivers sweetness through stevioside and rebaudioside compounds. These natural chemicals trigger our taste buds far more intensely than sucrose. Even a small dose can make your cup of coffee taste as sweet as adding a couple of spoonfuls of sugar.

Switching over sounds simple until you actually taste Stevia. Scores of people say it carries a licorice-like or even bitter aftertaste, especially in hot drinks or homemade baking. Personal experience lines up with these reports—adding Stevia to black tea or oatmeal often results in a clean sweetness up front, but there’s a botanical aftertaste that just won’t quit. Not everyone notices it, but enough people comment on it to make Stevia a love-it-or-leave-it option. Bakers especially get frustrated. Cookies, breads, or cakes need more than sweetness—they need caramelization, texture, and bulk—something Stevia alone can’t give. Swapping out sugar for Stevia in a favorite recipe can flatten the flavor and ruin tenderness.

Calorie Counts and Health Claims

One place Stevia absolutely shines: the calorie department. While cane sugar packs around 16 calories per teaspoon, Stevia runs virtually empty. Your body can’t break down its glycosides into caloric energy. Research published by the American Diabetes Association supports these calorie-free claims. That means Stevia earns high marks from people watching their weight, keeping tabs on their blood sugar, or managing diabetes. Less sugar also reduces risk of cavities and tooth decay.

Stevia’s sweetness doesn’t spike glucose levels the way sucrose does, and evidence continues to suggest it’s safe for regular use. The World Health Organization and FDA both back its use in reasonable daily quantities. My own family turned to Stevia when a doctor flagged pre-diabetes numbers. We didn’t miss sugary drinks, and blood sugar dropped noticeably over six months. While you still have to pay attention to total carbs in processed foods, a swap like this can move the needle for public health.

Why the Taste Difference Still Matters

Anyone flipping out a sugar bowl for a jar of Stevia bits quickly notices the taste trade-off. American consumers, in particular, expect sugar to enhance both sweet flavor and texture. Tablespoon for tablespoon, Stevia’s lack of bulk means it can't brown toast, thicken sauces, or give baked goods the mouthfeel people crave. Companies tackle that by mixing Stevia with fillers like maltodextrin or erythritol, but then you’re not avoiding additives. Homemade jams or birthday cakes just don’t come out the same unless you use ingredients the recipe needs—and that’s where sugar still rules.

Some folks learn to embrace Stevia’s quirks. Over time, the taste grows familiar, especially in cold drinks and un-baked snacks. Big soda brands now produce zero-calorie products using Stevia, and those usually get decent reviews. If you’re after fewer calories and don’t mind a different flavor, Stevia does the trick. For special-occasion desserts or crispy cookies, sugar remains unmatched.

Looking Forward: Finding the Balance

Instead of ditching sugar entirely, more people mix and match. Use Stevia in iced tea or protein shakes for everyday sweetening, and keep regular sugar for homemade pies, jams, or holidays. The difference matters from a health standpoint, especially as rates of obesity and diabetes climb. With honest conversations about what taste and texture mean in daily life, folks can make swaps in the places that matter most—saving calories without saying goodbye to flavor.

Can Stevia be used in cooking and baking?

Stevia: A Different Kind of Sweetness

Walk into any supermarket, and the big green-and-white boxes of stevia stand out from the rest. For years, people used sugar without too many choices. Now, more folks are searching for ways to satisfy cravings without spiking their blood sugar. Stevia has become their answer, coming from a South American plant with leaves that taste sweet but don’t load up calories. Unlike artificial substitutes, stevia comes from nature. For many cooks and bakers, the question comes up: can this green packet do what sugar does in the kitchen?

How Does Stevia Behave in Recipes?

My first experience with stevia involved sweetening my coffee. The taste felt pleasant—clean, sweet, with just a hint of bitterness if I overdid it. Later, I tried baking banana bread using stevia in place of sugar. The bread looked good, and the banana flavor popped, but the texture had changed. Stevia doesn’t caramelize or provide bulk the way sugar does. Cookies baked with stevia alone often turn out differently—softer, sometimes crumbly, but definitely sweet enough.

Sugar in recipes doesn’t just bring sweetness. It keeps cakes moist, creates a golden-brown crust, and helps yeast rise in dough. Stevia lacks these functions. Swapping stevia for sugar cup-for-cup can lead to some flat, pale treats. Many stevia-based sweeteners blend stevia extract with bulking agents, aiming to fill the gap left by sugar. Still, the results aren’t always a perfect match.

Why Bother Using Stevia?

Plenty of people count carbs for health reasons. People living with diabetes, for instance, often feel left out during pie season. Stevia lets them take part without pushing blood glucose through the roof. The FDA recognizes purified stevia extracts as safe. Research supports benefits like stable blood sugar and fewer empty calories. The American Diabetes Association lists stevia among several safe, zero-calorie sweetener options.

There’s something satisfying about watching friends and family dig into a cake you baked and being able to say, “No sugar added.” I’ve served stevia-sweetened cheesecake to guests who couldn’t tell the difference until I pointed out my secret ingredient.

Making Stevia Work in Your Baking

Switching from sugar to stevia in any dish works better with a few tricks. Most stevia products on shelves today offer conversion tables, since pure stevia extract packs a much stronger punch than sugar. Small amounts go a long way. Some brands sell cup-for-cup products, blending stevia with erythritol or other fillers to get closer to the bulk of sugar.

For recipes like jams or brittle, where texture depends on sugar, it’s tough to get identical results. In brownies, muffins, and quick breads, stevia steps in more naturally. To round out flavor, I’ve started adding a tablespoon or two of applesauce, yogurt, or mashed banana. That little bit of moisture makes up for the sugar’s absence and creates a soft crumb.

Not every swap works out of the gate. I keep a notebook of tweaks. Baking becomes a hands-on experiment, a bit of trial and error. In time, I get to know which dishes hold up well with stevia and which call for the real thing or a hybrid approach.

The Bottom Line

Stevia changes the baking game for folks watching sugar intake. It doesn’t perfectly replace sugar in every role, but with some creativity and patience, it opens up dessert menus to more people. Baking with stevia asks for a willingness to adjust, taste, and learn, but the rewards—enjoying cookies, cakes, and more without the sugar surge—make the effort worthwhile.

Stevia
Names
Preferred IUPAC name Rebaudioside A
Other names Sweetleaf
Sugarleaf
Stevia rebaudiana
Stevioside
Yerba dulce
Pronunciation /ˈstiː.vi.ə/
Preferred IUPAC name **(4aR,5S,6S,7R,9aS,9bR,11aR)-6-Carboxy-5-hydroxy-9b,11a-dimethyl-3-oxo-2-oxatetracyclo[6.4.1.0¹,⁶.0⁹,¹¹]dodecan-7-yl β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside**
Other names Sweetleaf
Sugarleaf
Stevia rebaudiana
Stevia Extract
Stevioside
Rebiana
Pronunciation /ˈstiː.vi.ə/
Identifiers
CAS Number 57817-89-7
Beilstein Reference 12154810
ChEBI CHEBI:66718
ChEMBL CHEMBL2107310
ChemSpider 21417473
DrugBank DB12809
ECHA InfoCard 03b7ee08-7d38-46c2-b436-842d43ad6df7
EC Number E960
Gmelin Reference 102455
KEGG C22189
MeSH D046097
PubChem CID 442089
RTECS number SLB9676500
UNII JN5J5VCS7D
CompTox Dashboard (EPA) DTXSID8011235
CAS Number 57817-89-7
Beilstein Reference 3913743
ChEBI CHEBI:6809
ChEMBL CHEMBL2108758
ChemSpider 11811318
DrugBank DB46542
ECHA InfoCard 06bfcd56-bb15-4403-bd21-e96c65e7b047
EC Number 960
Gmelin Reference 108406
KEGG C56035
MeSH D055713
PubChem CID 442089
RTECS number NL6658000
UNII GX187730L5
CompTox Dashboard (EPA) DTXSID7086253
Properties
Chemical formula C38H60O18
Molar mass 804.88 g/mol
Appearance Stevia appears as a white, crystalline powder or as small, green, dried leaves.
Odor Odorless
Density 0.8 g/cm³
Solubility in water Soluble in water
log P 4.27
Acidity (pKa) 12.67
Basicity (pKb) 12.6
Magnetic susceptibility (χ) Diamagnetic
Refractive index (nD) 1.3440 – 1.3470
Viscosity Low
Dipole moment 2.85 D
Chemical formula C38H60O18
Molar mass C38H60O18
Appearance white, crystalline powder
Odor Characteristic
Density 0.44 g/cm³
Solubility in water Soluble in water
log P 1.81
Acidity (pKa) 12.62
Basicity (pKb) 8.79
Magnetic susceptibility (χ) Diamagnetic
Refractive index (nD) 1.4430
Viscosity Viscosity: Low
Dipole moment 2.95 D
Pharmacology
ATC code A16AX—it is the ATC code string for Stevia.
ATC code A16AX—you requested string format only.
Hazards
Main hazards May cause allergic reactions, gastrointestinal discomfort, or interact with certain medications.
GHS labelling Not classified as hazardous according to GHS
Pictograms GlutenFree, Vegan, SugarFree, LowCalorie, NonGMO, NaturalSweetener
Signal word Warning
Hazard statements Not a hazardous substance or mixture.
Precautionary statements Keep out of reach of children. Store in a cool, dry place. Consult your physician before use if you are pregnant, nursing, taking medication, or have a medical condition.
NFPA 704 (fire diamond) 0-1-0
Autoignition temperature 440 °C
Lethal dose or concentration LD50 (rat, oral) > 15,000 mg/kg
LD50 (median dose) 15 g/kg
NIOSH DK8312000
PEL (Permissible) 250 mg/kg
REL (Recommended) 4 mg/kg bw
IDLH (Immediate danger) Not listed
Main hazards May cause allergic reactions, gastrointestinal discomfort, or interact with certain medications.
GHS labelling GHS07, GHS09
Pictograms 🌿🍬
Signal word No signal word
Hazard statements Not a hazardous substance or mixture according to the Globally Harmonized System (GHS)
Precautionary statements Keep in a cool, dry place, away from direct sunlight. Close the lid tightly after use. Keep out of reach of children.
NFPA 704 (fire diamond) 0-0-0-Special
Autoignition temperature 440 °C
Explosive limits Not explosive
Lethal dose or concentration LD50 (rat, oral): >15,000 mg/kg
LD50 (median dose) > 15 g/kg
PEL (Permissible) 300 mg/kg
REL (Recommended) 0.4 mg/kg bw
IDLH (Immediate danger) Not established
Related compounds
Related compounds Steviol
Rebaudioside A
Rebaudioside C
Stevioside
Related compounds Dulcin
Glycyrrhizin
Jabuticaba
Mogroside
Siraitia grosvenorii
Steviol glycoside
Sucralose
Thaumatin
Thermochemistry
Std molar entropy (S⦵298) St⦵298 = 713.0 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -1264 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -4802 kJ/mol