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Material Safety Data Sheet: Sorbitan Tristearate

Identification

Product Name: Sorbitan Tristearate
Chemical Name: Sorbitan Tristearate
Synonyms: Span 65, Sorbitan Stearate Triester
CAS Number: 26658-19-5
Recommended Use: Emulsifier in food, pharmaceuticals, and cosmetics
Supplier Details: Supplier names, addresses, and emergency contact phone numbers should be included as appropriate for workplace documentation.

Hazard Identification

GHS Classification: Not classified as hazardous under GHS regulations
Signal Word: Not applicable
Hazard Statements: Not considered to present a significant health hazard in normal use
Precautionary Statements: Avoid contact with eyes and prolonged skin contact; use in well-ventilated areas; handle bulk dust with care
Primary Route of Entry: Inhalation, skin and eye contact
Health Effects: Slight skin or eye irritation possible from prolonged or repeated exposure; ingestion can cause mild gastrointestinal discomfort if consumed in large quantities
Environmental Effects: No adverse environmental effects expected under normal conditions of use

Composition / Information on Ingredients

Chemical Name: Sorbitan tristearate
CAS Number: 26658-19-5
Content: Typically ranges from 98–100%
Impurities: Trace amounts of stearic acid, sorbitol esters, water
Molecular Formula: C60H114O8
Molecular Weight: 971.58 g/mol

First Aid Measures

General Advice: Remove from exposure and seek medical help if symptoms develop
Inhalation: Move affected person to fresh air; administer oxygen if symptoms appear severe
Skin Contact: Wash with plenty of soap and water; remove contaminated clothing and launder before reuse; seek medical attention if irritation persists
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present; continue rinsing and consult physician if irritation develops
Ingestion: Rinse mouth with water; do not induce vomiting; seek advice from medical professionals if large amounts are swallowed or symptoms persist

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, foam, carbon dioxide, or water spray
Unsuitable Media: High pressure water streams may spread burning material
Hazardous Combustion Products: Carbon oxides (CO, CO2), possible acrolein or aldehyde fumes
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Fire & Explosion Hazards: Can generate dust that may form explosive mixtures with air in unventilated areas; residue or vapors from heating can be irritating

Accidental Release Measures

Personal Precautions: Wear appropriate personal protective equipment including gloves, goggles, and dust mask; avoid breathing dust
Environmental Precautions: Prevent further leakage or spillage if safe to do so; avoid discharge into drains, surface waters, or soil
Clean-Up Methods: Sweep up spills and place in suitable, labeled containers for disposal; wash spill area with water to remove residues
Reference to Other Sections: Refer to sections on Personal Protection and Disposal Considerations

Handling and Storage

Precautions for Safe Handling: Avoid creating or breathing dust; use only with adequate ventilation; handle in accordance with good industrial hygiene and safety practice
Hygienic Measures: Wash hands after handling and before eating or smoking
Conditions for Safe Storage: Store in tightly closed containers in a cool, dry, and well-ventilated place; avoid excessive heat, sources of ignition, and strong oxidizers
Incompatible Materials: Strong acids, alkalies, and oxidizing agents can react and cause product deterioration
Storage Temperature: Ideally below 30°C to maintain product quality and stability

Exposure Controls and Personal Protection

Control Parameters: No occupational exposure limits established for this material
Engineering Controls: Provide general ventilation; use local exhaust during bulk handling or powder transfer
Personal Protective Equipment: Wear safety glasses or goggles, protective clothing, and chemical-resistant gloves
Respiratory Protection: Use dust mask or respirator in case of high airborne concentrations
Workplace Hygiene: No eating, drinking, or smoking in areas where this substance is handled, processed, or stored

Physical and Chemical Properties

Appearance: Waxy solid, beige to off-white flakes or granules
Odor: Mild, characteristic fatty odor
pH: Not applicable (insoluble in water)
Melting Point: 54–57°C
Boiling Point: Decomposes before boiling
Flash Point: >230°C (closed cup)
Flammability: Not classified as flammable; may burn at high temperatures
Vapor Pressure: Negligible at room temperature
Solubility: Practically insoluble in water; soluble in oils and organic solvents
Density: 1.0–1.1 g/cm³
Partition Coefficient (log Kow): Approx. 27 (estimated, very lipophilic)
Viscosity: Not determined

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Non-reactive in normal use
Thermal Decomposition: Excessive heat can lead to decomposition, releasing irritating fumes and gases
Hazardous Polymerization: Product does not undergo hazardous polymerization
Incompatible Materials: Strong acids, strong bases, and oxidizing agents may accelerate degradation
Conditions to Avoid: Prolonged exposure to high temperatures, open flames, strong oxidizers

Toxicological Information

Acute Toxicity: Low toxicity; oral LD50 in rats reported to exceed 10,000 mg/kg
Skin Irritation: Mild, especially with prolonged or repeated exposure
Eye Contact: May cause minor irritation or redness
Inhalation: Dust may irritate respiratory tract
Sensitization: Not expected to cause skin sensitization
Chronic Effects: No chronic health hazards or long-term effects have been identified in typical use levels
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA
Mutagenicity and Reproductive Toxicity: No evidence of mutagenic or reproductive toxicity effects observed in studies

Ecological Information

Ecotoxicity: Not expected to be harmful to aquatic life; derived from natural fatty acids
Persistence and Degradability: Biodegradable; breaks down over time by natural microbial activity
Bioaccumulation Potential: Not expected to bioaccumulate significantly due to poor water solubility
Mobility in Soil: Low mobility, binds tightly to soil particles; unlikely to contaminate groundwater
Other Adverse Effects: No known significant effects or hazards to the environment

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations; non-hazardous under normal conditions
Product Disposal: Can be disposed of by incineration or landfill after confirming compliance with local environmental regulations
Contaminated Packaging: Rinse thoroughly before recycling or disposal; follow local waste management policies
Special Precautions: Avoid contamination of water bodies or drains with waste material

Transport Information

UN Number: Not regulated for transport
Transport Hazard Class: Not classified as dangerous goods under ADR, IMDG, IATA
Packing Group: None assigned
Special Precautions for Transport: Keep containers tightly closed during transit and store in a cool, ventilated area to avoid decomposition
Environmental Hazards: Not a marine pollutant

Regulatory Information

Regulatory Status: Not classified as a hazardous substance or mixture under OSHA HazCom, REACH, or GHS
Inventory Listing: Listed on TSCA, EINECS/ELINCS, AICS, and other major chemical inventories
Food Additive: Permitted as an emulsifier in foods in many countries; regulated by agencies like FDA and EFSA
SARA Title III Sections 302/304/311/312/313: Not subject to reporting requirements
California Proposition 65: This product is not known to contain any chemicals currently listed as carcinogenic or reproductive toxins
Other Regulations: Compliance required with all applicable workplace safety and chemical management standards, including right-to-know and labeling requirements