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Product Name: Sodium Starch Phosphate
Synonyms: Starch sodium phosphate, Sodium salt of phosphate esterified starch
Chemical Formula: Variable (based on starch origin), general form (C6H10O5)nNa
CAS Number: 7558-80-7
Intended Use: Disintegrant in pharmaceutical tablets, food additive, binding agent
Recommended Restrictions: Not intended for uses other than those identified above
Supplier Identification: Company name, address, phone, emergency contact
Classification: Not classified as hazardous according to GHS
Physical Hazards: Fine powder may form explosive dust-air mixtures
Health Hazards: May cause mild transient irritation to eyes and respiratory tract if inhaled; not sensitizing or carcinogenic; ingestion of typical amounts not a health hazard
Environmental Hazards: Not expected to present significant dangers to the environment
Signal Word: None
Pictogram: None
Label Elements: None
Other Hazards: Slippery when spilled, can increase fall risk on hard surfaces
Chemical Ingredient: Starch, esterified with sodium phosphate
Concentration: 100% (contains sodium, phosphate, and starch moieties)
Impurities/Additives: May contain trace quantities of starting starch impurities, water, or phosphate esters; no hazardous additives present
CAS Number: 7558-80-7
EC Number: 231-373-2
General Advice: Remove affected individual from exposure, seek medical attention for any unusual symptoms
Eye Contact: Rinse with plenty of clean water; remove contact lenses if present; continue rinsing for several minutes; seek medical attention if irritation persists
Skin Contact: Wash with mild soap and water; remove contaminated clothing
Inhalation: Move to fresh air, support breathing, consult physician for any respiratory discomfort
Ingestion: Rinse mouth; drink water; seek medical attention for discomfort, especially in large amounts
Chronic Exposure: Symptoms rarely persist; consult medical professional for ongoing effects
Most Important Symptoms: Mild irritation, coughing, sneezing if inhaled
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Specific Hazards: Dust may form explosive mixtures with air; combustion may produce carbon monoxide and carbon dioxide
Special Protective Equipment: Use self-contained breathing apparatus and protective clothing for large fires
Other Recommendations: Remove material from fire area if possible without risk; cool containers with water spray; avoid generating dust clouds
Thermal Decomposition Products: Oxides of carbon, possible sodium compounds, water vapor
Personal Precautions: Avoid breathing dust; use appropriate PPE, including dust masks and goggles; ensure adequate ventilation
Environmental Precautions: Prevent large amounts from entering drains, sewers, or watercourses; small releases can be handled by routine cleanup
Methods for Containment: Stop spillage; cover with plastic sheet to minimize spreading of dust
Cleaning Methods: Sweep carefully to avoid dust formation; transfer spilled material to clean, dry containers for disposal or reuse; wash area with water to remove residues
Disposal of Collected Material: See Disposal Considerations
Handling: Minimize dust generation; use local exhaust or general ventilation; avoid inhalation or contact with eyes; do not eat, drink, or smoke while using
Storage: Keep containers tightly closed in dry, cool, well-ventilated area; store away from incompatible materials such as strong oxidizers; avoid sources of ignition including static electricity
Special Requirements: Store bulk bags on pallets, keep away from floor moisture, separate from food and feed where different regulatory standards apply
Hygiene Practices: Wash hands after handling; remove contaminated clothing before entering eating areas
Occupational Exposure Limits: No specific OSHA or ACGIH exposure limits; consider general nuisance dust limits (10 mg/m3 total, 3 mg/m3 respirable fraction)
Engineering Controls: Provide adequate ventilation, preferably local exhaust ventilation to keep airborne levels low
Personal Protective Equipment:
Gloves (PVC or nitrile) for skin protection on prolonged exposure, safety goggles for eye protection, N95 dust mask or equivalent for respiratory protection
Environmental Exposure Controls: Prevent accumulation and release of dust in the workplace and surroundings
Other Protective Measures: Use coveralls, lab coats, or aprons to prevent contact with large amounts; safety showers and eyewash stations recommended in bulk handling areas
Appearance: White to off-white, fine powder or granules
Odor: Nearly odorless or faint starchy odor
Odor Threshold: Not established
pH: 8 to 11 (1% solution in water)
Melting Point/Freezing Point: Not applicable (decomposes upon heating)
Boiling Point/Range: Not applicable
Flash Point: Not applicable
Evaporation Rate: Not relevant for powder
Flammability: May support combustion as organic powder, produces combustible dust clouds
Upper/Lower Flammability or Explosive Limits: Not determined
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Relative Density: Approximately 1.5 g/cm3
Solubility: Swells and gels in water, dispersible but not truly soluble
Partition Coefficient: Not applicable
Auto-Ignition Temperature: > 390°C
Decomposition Temperature: 200–250°C (thermal degradation)
Viscosity: Not relevant
Explosive Properties: Dust may explode if suspended in air and ignited
Oxidizing Properties: Not considered an oxidizer
Chemical Stability: Stable under recommended storage and usage conditions
Reactivity: No dangerous reactions known under normal conditions; susceptible to hydrolysis in strong acid/base
Possibility of Hazardous Reactions: Dust may ignite under certain conditions
Conditions to Avoid: Moisture, proximity to sources of ignition, generation of airborne dust
Incompatible Materials: Strong oxidizers (such as peroxides), concentrated acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, sodium compounds
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Practically non-toxic; oral LD50 (rat) > 5,000 mg/kg
Skin Corrosion/Irritation: Not irritating to skin under normal conditions
Serious Eye Damage/Irritation: Mild discomfort possible upon contact
Respiratory or Skin Sensitization: Not sensitizing in animal or human studies
Germ Cell Mutagenicity: Not expected to be mutagenic
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: Not expected based on structure or available data
STOT – Single Exposure: Transient respiratory irritation possible with excessive dust
STOT – Repeated Exposure: No known effects
Other Effects: Chronic, repeated overexposure to dust may aggravate pre-existing respiratory problems such as asthma; no further systemic toxicity identified
Toxicity: Not considered harmful to aquatic environments at normal concentrations; fish and invertebrate toxicity studies show high LC50 values
Persistence and Degradability: Readily biodegradable, breaks down by microbial action in soil and water
Bioaccumulative Potential: Not expected to bioaccumulate due to large molecular size and rapid degradation
Mobility in Soil: Low; material settles readily and is assimilated by soil microorganisms
Other Adverse Effects: None expected; product is a modified naturally occurring polymer
Waste Treatment Methods: Can be landfilled or incinerated according to local regulations; preferred disposal is by incineration in accordance with local, regional, national, and international regulations
Container Disposal: Rinse empty containers before recycling; do not reuse for food, feed, or potable substances
Special Precautions: Avoid dispersion of dust during disposal; sweep up using methods that prevent airborne particles
UN Number: Not regulated as a dangerous good
UN Proper Shipping Name: Not regulated
Transport Hazard Class: None assigned
Packing Group: None
Environmental Hazards: Not regulated; no marine pollutant risk
Special Precautions for User: Protect containers from physical damage, wetting, and ignition sources
Transport in Bulk (IMDG/IBC): Not controlled under ADR/RID/IMDG/IATA
USA: Meets requirements of FDA as food additive and pharmaceutical excipient; not on TSCA as hazardous
Canada: DSL/NDSL Listed; compliant for use meeting Canadian regulations on excipients
EU: E1422 (food additive); REACH compliant as polymeric substance
Other Regulations: Not classified as hazardous according to OSHA Hazard Communication Standard, EU CLP, or GHS
Labeling Requirements: No specific pictogram required; safety recommendations based on nuisance dust considerations
Restrictions: Some countries may have use or concentration limits in food or pharmaceuticals
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
