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Material Safety Data Sheet for Sodium Saccharin

Identification

Product Name: Sodium Saccharin
Chemical Formula: C7H4NNaO3S
Synonyms: O-sulfobenzoic acid imide sodium salt, E954
CAS Number: 128-44-9
Molecular Weight: 205.17 g/mol
Recommended Uses: Sweetener in food and pharmaceuticals, laboratory reagent
Supplier Details: Manufacturer and distributor contact information, address, emergency telephone number

Hazard Identification

Classification: Eye Irritation Category 2B, Hazardous to the aquatic environment, category 3
Signal Word: Warning
Hazard Statements: Causes eye irritation, may cause mild skin irritation, potentially harmful to aquatic life with long-lasting effects
Pictograms: Exclamation mark
Precautionary Statements: Avoid release to the environment, wash exposed skin thoroughly after handling, wear appropriate eye protection, avoid direct inhalation or ingestion

Composition / Information on Ingredients

Chemical Name: Sodium Saccharin
Percentage: Typically >98% by weight
Impurities: Water (up to 1.5%), minor residual organic and inorganic impurities depending on source

First Aid Measures

Eye Contact: Rinse immediately with plenty of water for 10–15 minutes, keep eyes wide open while rinsing, seek medical advice if irritation persists
Skin Contact: Wash with water and soap, remove contaminated clothing, get medical help if any redness or discomfort continues
Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical attention if symptoms arise
Ingestion: Rinse mouth, drink water if conscious, do not induce vomiting without professional advice, contact medical staff for guidance

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: No specific restriction but avoid strong water jets
Hazards from Combustion: Oxides of sulfur, nitrogen oxides, and sodium oxides released under intense heating
Protective Equipment: Wear full protective suit and approved self-contained breathing apparatus
Advice for Firefighters: Move containers away from fire, use water spray to cool exposed containers, prevent runoff from contaminating water sources

Accidental Release Measures

Personal Precautions: Use personal protective equipment, avoid breathing dust, ensure adequate ventilation
Environmental Precautions: Prevent further leakage or spillage if safe, do not allow product to enter drains or watercourses
Clean-up Methods: Pick up mechanically, sweep or shovel material into suitable container for disposal, avoid creating dust, clean contaminated area with wet cloths

Handling and Storage

Handling: Use with adequate ventilation, avoid dust generation, direct contact with skin and eyes not recommended, wash hands thoroughly after handling
Storage: Store in closed containers in cool, dry, well-ventilated area, keep away from moisture, strong acids and oxidizers, maintain product integrity through regular inspection

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established specifically for sodium saccharin by OSHA or ACGIH
Engineering Controls: Local exhaust or general ventilation to control airborne dust, recommended if workplace concentrations rise
Personal Protective Equipment: Safety goggles, chemical-resistant gloves, dust mask or respirator if exposure is likely to exceed recommended limits, protective clothing in bulk handling situations
Hygiene Measures: Wash hands, face, and any exposed skin thoroughly after handling, avoid eating, drinking or smoking in work area

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Odorless
pH (1% solution): 6.5–8.0
Melting Point/Freezing Point: Decomposes at about 228°C instead of melting
Boiling Point: Not applicable
Solubility in Water: Approximately 42.5 g/100 ml at 20°C
Partition Coefficient (log Kow): -2.1 (low potential for bioaccumulation)
Vapor Pressure: Not significant at room temperature
Density: About 0.8 g/cm³
Other: Stable under normal storage and use conditions, hygroscopic

Stability and Reactivity

Reactivity: Not highly reactive, poses no significant risk of violent chemical reaction
Chemical Stability: Stable under typical use and storage
Incompatible Materials: Strong acids, strong oxidizing agents
Hazardous Decomposition Products: Sulfur oxides, nitrogen oxides, sodium oxides produced by combustion or thermal decomposition
Hazardous Reactions: No dangerous reactions expected under recommended conditions

Toxicological Information

Acute Toxicity: Low acute toxicity by oral, dermal, or inhalation exposure; LD50 (rat, oral) approximately 17,000 mg/kg
Skin Corrosion/Irritation: Not classified as corrosive, rare mild irritation possible
Serious Eye Damage/Irritation: Possible mild irritation, usually temporary
Respiratory or Skin Sensitization: Not expected to cause sensitization
Chronic Effects: No evidence of carcinogenicity under intended use, based on current regulatory review by JECFA, FDA, EFSA; considered safe at approved levels
Mutagenic, Reproductive, Developmental Toxicity: Studies suggest no significant effects
Other Information: Higher doses may produce gastric discomfort; people with sulfonamide allergies urged to use caution

Ecological Information

Aquatic Toxicity: Moderately toxic to aquatic organisms in concentrated form
Persistence and Degradability: Partially biodegradable, persists in some environments under certain conditions
Bioaccumulative Potential: Low, as indicated by partition coefficient
Mobility in Soil: High, dissolves easily in water, may enter groundwater
Other Adverse Effects: Avoid release to environment, long-term impact remains under environmental review

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations, do not discharge into drains or watercourses
Product Disposal: Small quantities can usually be disposed of as general chemical waste, larger volumes require handling as hazardous waste
Contaminated Packaging: Clean containers before recycling or disposal, follow local legislation concerning packaging and residues
Precautions: Wear suitable protective equipment to manage clean-up and disposal safely

Transport Information

UN Number: Not regulated as a dangerous good under UN transport guidelines
Proper Shipping Name: Sodium Saccharin
Hazard Class: Not classified as hazardous
Packing Group: Not applicable
Special Precautions: Ensure package is undamaged, keep container sealed, prevent moisture ingress during shipment
Environmental Hazards: Not a marine pollutant under IMO criteria
Transport Notes: Typical commercial quantities do not require special labeling or placarding

Regulatory Information

Safety, Health, and Environmental Regulations: Sodium saccharin is generally recognized as safe by international agencies, including FDA (21 CFR 180.37) and EFSA; subject to purity and labeling requirements
Inventory Listings: Listed on U.S. TSCA, EU EINECS, Canada DSL, Australia AICS, Japan ENCS, and China IECSC
Restrictions: Permitted use levels in foods are regulated by national and regional authorities
Other Information: Always check workplace and local safety data for updates, label all containers clearly, maintain compliance with occupational health standards, ensure MSDS is accessible to workers and emergency responders