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Chemical Name: Sodium Hyaluronate
Synonyms: Hyaluronic Acid Sodium Salt, Sodium Hyaluronan
CAS Number: 9067-32-7
Relevant Uses: Used in ophthalmic surgery, dermal fillers, topical wound healing, joint pain relief, cosmetic products
Manufacturer: Contact details on packaging or on official documentation
Emergency Contact: Use local emergency numbers and poison control centers
Classification: Not considered hazardous under OSHA Hazard Communication Standard
GHS Label Elements: Not required for this substance
Hazards: Dust may cause mild mechanical irritation
Precautionary Statements: Avoid inhaling powder, avoid contact with eyes, wash hands after handling, keep away from food and drinks
Other Hazards: Not classified as flammable, explosive, or reactive under normal conditions
Ingredient: Sodium Hyaluronate
Purity: Typically >90%
Impurities: Trace levels of water, sodium chloride, protein residues depending on grade and manufacturing
Molecular Formula: (C14H20NNaO11)n
Appearance: White to off-white powder, sometimes granular
Inhalation: Move person to fresh air, seek medical attention if irritation or coughing persists
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, seek medical advice if irritation continues
Ingestion: Rinse mouth, drink water, seek medical attention if symptoms appear or persist
Special Note: Individuals with hypersensitivity to sodium hyaluronate may require specific medical care
Suitable Extinguishing Media: Use water, carbon dioxide, dry chemical, or foam as needed
Specific Hazards: Burning can produce carbon monoxide, carbon dioxide, nitrogen oxides, sodium oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Advice for Firefighters: Use standard methods, avoid inhaling combustion vapors, control runoff
Explosion Hazard: Powder may form combustible dust-air mixtures in high concentrations
Personal Precautions: Wear dust mask, gloves, protective clothing, avoid generating dust
Environmental Precautions: Prevent large spills from entering water courses
Methods for Cleanup: Sweep up and collect for proper disposal, avoid creating dust clouds, ventilate area, wash residual material with water
Small Spills: Wipe with damp cloth
Large Spills: Use vacuum with HEPA filter or wet sweeping to minimize dust generation
Handling: Use with adequate ventilation, minimize dust generation, wear protective gear, avoid eye contact
Storage: Store tightly closed in cool dry place, protect from moisture, heat, and incompatible substances
Incompatibilities: Strong oxidizing agents
Hygiene Measures: Wash hands after handling product, do not eat or drink during use
Storage Containers: Use original packaging or moisture-proof containers
Occupational Exposure Limits: No established exposure limits for sodium hyaluronate
Engineering Controls: Local exhaust ventilation, safety showers, and eye wash stations recommended
Personal Protective Equipment: Dust mask or respirator if dust cannot be avoided, safety goggles, gloves, protective clothing
Hygienic Practices: Do not smoke, eat, or drink during handling
Environmental Exposure Control: Prevent substantial spills from reaching sewage or waterways
Appearance: White to off-white powder
Odor: Odorless or mild
pH: Around 6.0-7.5 (1% solution)
Melting Point: Decomposes before melting
Solubility: Soluble in water, forms viscous solutions
Boiling Point: Not applicable
Specific Gravity: 0.7-0.9 (bulk powder)
Vapor Density: Not relevant
Evaporation Rate: Not applicable
Other Properties: Generates slippery solutions, absorbs moisture from air
Chemical Stability: Stable under normal conditions
Conditions to Avoid: Excess heat, moisture, open flame, sources of ignition
Incompatible Materials: Strong oxidizing substances
Hazardous Decomposition Products: Burning produces carbon oxides, nitrogen oxides, sodium compounds
Polymerization: Does not undergo hazardous polymerization
Acute Toxicity: Low, not expected to cause acute health effects in normal use
Skin Irritation: Not classified as irritant, possible mild mechanical irritation
Eye Irritation: Dust may result in mild redness and discomfort
Respiratory: Dust may cause temporary coughing or sneezing in sensitive individuals
Chronic Exposure: No evidence of chronic toxicity or carcinogenicity from available data
Sensitization: Not recognized as skin or respiratory sensitizer
Mutagenicity/Reproductive Toxicity: Data show no genotoxic or reproductive toxicity concerns under normal usage
Ecotoxicity: Not regarded as dangerous to aquatic life at low concentrations
Persistence and Degradability: Biodegradable in natural environments
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: High water solubility supports mobility, rapidly broken down by microorganisms
Other Adverse Effects: On large accidental release, local oxygen depletion may occur during bio-degradation
Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations
Unused Product: Landfill or incineration as allowed
Contaminated Packaging: Rinse and recycle or dispose to approved waste handler
Special Precautions: Prevent material from entering public drains or surface waters
Recommendation: Follow instructions specific to local environmental authority
UN Number: Not regulated as hazardous for transport
Proper Shipping Name: Sodium Hyaluronate
Transport Hazard Class: Not classified as dangerous
Packing Group: Not assigned
Special Transport Precautions: Keep containers sealed, protect from moisture during transit
Transport Label: No label required for ground, air, or sea transport
OSHA Status: Not listed as hazardous
SARA Title III: Not regulated
TSCA (US): Exempt or listed
REACH (EU): Registered as a substance under European chemical regulations
Other: No components on lists of carcinogens—such as IARC, NTP, or ACGIH
Label Statements: Not required, voluntary safety language often applied
Workplace Regulation: Follow standard good laboratory practice for routine safe handling
