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Sodium Glutamate Material Safety Data Sheet (MSDS)

Identification

Product Name: Sodium Glutamate
Other Names: Monosodium Glutamate, MSG, E621
Chemical Formula: C5H8NO4Na
CAS Number: 142-47-2
Recommended Use: Flavor enhancer for food processing, laboratory reagent, industrial applications
Supplier Details: Manufacturer/Supplier address, emergency contact number, email, local distributor information

Hazard Identification

Classification: Not classified as hazardous according to GHS
Physical Hazards: Not flammable, not explosive, no oxidizing potential
Health Hazards: Inhalation may cause slight respiratory irritation, dust may irritate eyes, ingestion may cause mild gastrointestinal discomfort
Precautionary Statements: Avoid dust generation, use adequate ventilation, prevent contact with eyes, wash hands thoroughly after handling
Signal Word: None
Hazard Pictograms: None required
Other Dangers: Large spills may cause slippery surfaces, prolonged exposure to high concentrations of dust may aggravate pre-existing respiratory conditions

Composition / Information on Ingredients

Chemical Name: Monosodium Glutamate
Synonyms: MSG, Sodium Hydrogen Glutamate
Concentration: ≥99%
Impurities: Trace minerals, water less than 1%
EC Number: 205-538-1
Molecular Weight: 169.11 g/mol

First Aid Measures

Inhalation: Move individual to fresh air, seek medical advice if discomfort persists
Eye Contact: Rinse eyes gently with water for several minutes, remove contact lenses, consult physician if irritation develops
Skin Contact: Rinse affected skin with plenty of water, remove contaminated clothing
Ingestion: Rinse mouth, drink water, seek medical attention if symptoms arise
Important Symptoms and Effects: Mild irritation to respiratory tract, eyes and skin, upset stomach if large amounts are ingested
Notes for Physicians: Symptomatic treatment only

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical powder, foam, carbon dioxide
Unsuitable Media: No special restrictions
Special Hazards: Product does not burn, toxic gases such as nitrogen oxides or sodium oxides may form upon strong heating
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Advice for Firefighters: Cool containers exposed to fire with water spray
Explosion Data: Not sensitive to mechanical impact or static discharge

Accidental Release Measures

Personal Precautions: Wear dust mask, safety goggles, and gloves
Environmental Precautions: Prevent entry into sewers or water sources, avoid dust dispersal
Cleanup Methods: Sweep or vacuum up spilled material without stirring up dust, place in label container for disposal, wash area with plenty of water
Reference to Other Sections: For personal protection see Section on Exposure Controls/Personal Protection

Handling and Storage

Handling: Avoid generating dust, use local exhaust ventilation, handle with care to prevent packaging breaks
Storage: Keep containers tightly closed in a cool, dry, well-ventilated place, store away from strong acids and oxidizing agents
Incompatible Materials: Strong acids, strong oxidizers
Other Precautions: Store at room temperature, keep away from moisture and direct sunlight, stack bags properly to prevent falls

Exposure Controls and Personal Protection

Control Parameters: No established occupational exposure limit for sodium glutamate
Engineering Controls: Use mechanical ventilation when handling large quantities, ensure eyewash stations and washing facilities are nearby
Personal Protective Equipment: Safety goggles, dust mask/respirator (in case of dust), gloves, laboratory coat or apron
Hygiene Measures: Wash hands after handling, do not eat, drink or smoke in work area, remove contaminated clothing and wash before reuse
Environmental Exposure Controls: Use protective barriers to prevent spills entering surface water or sewers

Physical and Chemical Properties

Appearance: White crystalline powder or granules
Odor: Practically odorless
pH (10% solution): 6.7 – 7.2
Melting Point: Decomposes above 232°C
Boiling Point: Not applicable
Solubility: Very soluble in water (740 g/L at 25°C), insoluble in ethanol
Vapor Pressure: Negligible
Density: Approximately 1.6 g/cm³ (bulk)
Flash Point: Not flammable
Explosive Limits: Not applicable
Partition Coefficient (n-octanol/water): -3.31

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: May react with strong acids or oxidizers
Conditions to Avoid: Excessive heat, moisture, direct sunlight
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, sodium oxides upon strong heating or combustion
Incompatible Materials: Strong acids, oxidizing agents

Toxicological Information

Acute Toxicity: Rat oral LD50 > 15,000 mg/kg
Skin Corrosion/Irritation: Not a primary skin irritant
Serious Eye Damage/Irritation: Mild, transient irritation possible
Respiratory/Skin Sensitization: Not known as a sensitizer
Carcinogenicity: Not listed by IARC, OSHA, NTP
Reproductive Toxicity: No adverse reproductive effects reported in animal studies
Target Organ Effects: May aggravate asthma or other respiratory conditions upon inhalation of dust
Other Effects: High oral doses may cause headaches, nausea (“Chinese Restaurant Syndrome” reported anecdotally)

Ecological Information

Ecotoxicity: Not expected to be harmful to aquatic organisms at environmental concentrations
Persistence and Degradability: Readily biodegradable, rapidly metabolized by microorganisms
Bioaccumulative Potential: Low, does not bioaccumulate
Mobility in Soil: Highly soluble in water, likely to move through soil with water
Other Adverse Effects: No data indicating significant risk to the environment, release of large quantities may cause oxygen depletion in water bodies

Disposal Considerations

Waste Treatment Methods: Dispose of unused product in accordance with local, regional, and national regulations
Product Disposal: Can be disposed of as non-hazardous waste, avoid large releases to wastewater systems
Packaging Disposal: Triple rinse and recycle or dispose in compliance with regulations, minimize dust generation upon disposal
Precautions: Do not incinerate large quantities, do not allow product to contaminate natural water sources

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as dangerous for transport
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Transport Precautions: Keep container sealed and protected from physical damage, avoid moisture ingress, store away from incompatible materials
Special Transport Notes: No special restrictions for air, sea, rail, or road transport

Regulatory Information

Global Inventory Status: Listed on US TSCA, EU REACH, Canada DSL, Australia AICS, Japan ENCS
Labeling Requirements: Not required to carry hazard symbol or signal word under GHS
Food Additive Status: Approved by US FDA, EU EFSA, Codex Alimentarius for use as flavor enhancer (E621), with specific maximum usage levels
Workplace Safety: Refer to local and national regulations on occupational exposure to chemical dusts
Other Regulations: Subject to chemical import/export control in certain regions, safety training for handling and storage required in many workplaces