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Chemical Name: Sodium Cyclamate
Synonyms: Cyclamic acid sodium salt, cyclohexylsulfamic acid sodium salt
CAS Number: 139-05-9
Recommended Use: Artificial sweetener in food processing, beverages, pharmaceuticals
Supplier Information: Manufacturer and distributor details, including emergency telephone number, city, and postal code
Product Form: Solid, typically marketed as crystals, granules, or powder
Molecular Formula: C6H12NNaO3S
Molecular Weight: 201.22 g/mol
GHS Classification: Not classified as hazardous based on current regulatory lists
Primary Hazards: Eye and skin irritation following direct contact; respiratory tract irritation through inhalation of dust
Signal Word: None, due to generally low acute toxicity
Hazard Statements: Prolonged or repeated exposure may cause mild irritation to mucous membranes
Precautionary Statements: Avoid inhaling dust or getting substance in eyes; wear adequate protection when handling
Appearance: White, odorless, crystalline material
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Chronic Effects: Reports of bladder effects in laboratory animals at high doses
Carcinogenic Categories: Not considered to be carcinogenic to humans based on available studies
Main Ingredient: Sodium Cyclamate
Chemical Composition: Above 98% purity
Impurities: Minor cyclohexylamine, inorganic salts (traces)
Formulation: May include non-hazardous fillers in commercial preparations
Inhalation: Move the exposed person to fresh air; seek medical attention if symptoms persist, such as coughing or difficulty breathing
Skin Contact: Wash off with plenty of water and mild soap; remove contaminated clothing. Medical attention may be necessary if irritation continues.
Eye Contact: Immediately flush area with plenty of water for at least fifteen minutes; lift eyelids occasionally; contact a medical professional if irritation persists
Ingestion: Rinse mouth with water; seek medical advice if large quantities are swallowed or adverse effects develop
Note to Medical Personnel: Treat symptoms and provide supportive care as needed
Suitable Extinguishing Media: Use dry chemical, foam, carbon dioxide, or water spray for extinguishing
Unsuitable Extinguishing Media: High-pressure water jets may spread dust
Fire Hazards: Combustible dust can form explosive mixtures in air under certain conditions; decomposes at high temperature
Hazardous Combustion Products: Oxides of sulfur, nitrogen oxides, sodium oxide, and other unidentified toxic gases
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing
Additional Information: Prevent fire water runoff from contaminating soil or water systems
Personal Precautions: Wear respiratory protective equipment, gloves, protective eyewear
Environmental Precautions: Avoid runoff to sewers, surface water, or groundwater
Spill Cleanup Methods: Sweep up spilled material without generating dust; collect in properly labeled containers for disposal; wash site with water after cleanup
Disposal: Dispose of waste according to national, regional, and local regulations
Precautions for Safe Handling: Avoid creating dust; ensure adequate ventilation in processing areas; do not eat, drink, or smoke while handling; use non-sparking tools
Storage Conditions: Store tightly closed containers in a cool, dry, well-ventilated place; keep away from strong acids or oxidizers; protect from moisture
Incompatibilities: Keep away from oxidizing materials and acids
Exposure Limits: No established occupational exposure limits in most countries
Engineering Controls: Use local exhaust ventilation to minimize airborne dust
Personal Protective Equipment: Wear dust mask, safety goggles, gloves, and protective clothing as needed
Hygiene Measures: Wash hands thoroughly after handling; remove contaminated clothing and wash before reuse
Appearance: White crystalline powder or granules
Odor: Odorless
Melting Point: 270°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Highly soluble in water, slightly soluble in ethanol
Density: 1.83 g/m³
pH (5% solution): 5.5–7.5
Vapor Pressure: Negligible
Partition Coefficient: Log Kow approximately -3.2
Flash Point: Not applicable
Flammability: Not classified as flammable, may form combustible dust clouds
Chemical Stability: Stable under normal storage and usage conditions
Reactivity: Reacts with strong acids; may liberate toxic gases (such as sulfur oxides) during decomposition
Conditions to Avoid: Excessive heat, open flames, sources of ignition, moisture
Incompatible Materials: Strong acids, oxidizing agents
Hazardous Decomposition Products: Sulfur oxides, nitrogen oxides, sodium oxide, and potentially irritating fumes
Acute Toxicity: Oral (rat) LD50: 17,000 mg/kg, considered low toxicity
Skin Irritation: Not a skin sensitizer under normal conditions, causes mild irritation with prolonged contact
Eye Irritation: Mild, transient irritation in animal studies
Inhalation: High concentrations of dust can cause irritation to the respiratory tract
Chronic Effects: High-dose animal studies have shown bladder effects, though not confirmed in humans at normal exposure
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity/Genotoxicity: No evidence of mutagenic or genotoxic effects in standard studies
Reproductive Toxicity: Not identified as a reproductive or developmental toxin
Aquatic Toxicity: Low toxicity to aquatic organisms; typical LC50 (fish, 96 hr) > 1000 mg/L
Degradability: Biodegradable under aerobic conditions, though biodegradation may occur slowly
Bioaccumulation: Low potential due to high water solubility and low partition coefficient
Mobility in Soil: Highly mobile due to solubility in water; likely to enter water systems if released
Other Ecological Effects: No known significant environmental hazard; large releases could promote local eutrophication
Waste Disposal Methods: Dispose as non-hazardous chemical waste through licensed waste disposal contractor
Contaminated Packaging: Rinse containers with water, treat rinsate as waste; recycle or dispose of safely
Regulations: Follow local, state, and national environmental regulations; avoid release into the environment
UN Number: Not classified as a dangerous good for transport
Proper Shipping Name: Sodium Cyclamate
Hazard Class: No hazard class assigned
Packing Group: None
Labels Required: No special labeling required
Special Precautions: Prevent spillage and formation of dust during transport; use sealed packaging
FDA Status: Subject to regulations in some countries for food use; banned in the US as a food additive but permitted in many other countries
EINECS Number: 205-348-9
TSCA Listing: Listed
Additional Regulations: May be subject to workplace exposure controls under occupational health and safety guidelines
Labelling Requirements: Not hazardous under GHS; labeling should indicate proper handling and storage instructions
International Inventories: Listed in chemical inventories in major economies such as EU, Canada, Japan
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
