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Material Safety Data Sheet (MSDS) for Sodium Chondroitin Sulfate

1. Identification

Product Name: Sodium Chondroitin Sulfate
Chemical Formula: (C13H20NNaO15S)n
Synonyms: Chondroitin Sulfate Sodium Salt, Chonsurid, Chondrolectin
Intended Use: Used in pharmaceutical, nutraceutical, dietary supplements, and research applications
Manufacturer: Contact details required for supplier or importer
Emergency Phone: Provided by the local distributor or regional poison control center

2. Hazard Identification

Hazard Class: Not classified as hazardous per GHS (Globally Harmonized System)
Potential Health Effects: May cause mild irritation to eyes, skin, or respiratory tract if inhaled or exposed in large amounts
GHS Pictograms: Not required
Signal Word: None
Precautionary Statements: Avoid inhalation of powder. Use local exhaust ventilation if dust occurs. Wash hands after handling.
Other Hazards: No specific hazards known under normal use

3. Composition / Information on Ingredients

Chemical Name: Sodium Chondroitin Sulfate
CAS Number: 9082-07-9
Concentration: 85–100%
Impurities: Moisture content up to 12%, low-level protein residues may be present from animal cartilage sources

4. First Aid Measures

Inhalation: Move affected person to fresh air. Seek medical attention if symptoms develop.
Skin Contact: Rinse area with soap and water. Remove contaminated clothing. Medical attention rarely required.
Eye Contact: Rinse eyes cautiously with water for several minutes. Remove any contact lenses. Seek attention if irritation persists.
Ingestion: Rinse mouth with water. Drink water if conscious. Medical intervention not usually needed except in case of large quantities or symptoms

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Specific Hazards: Upon burning, may release oxides of carbon, sulfur compounds, or nitrogen oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Additional Information: Powder can form combustible dust-air mixtures. Use conventional methods to prevent the spread of dust and check for secondary explosions

6. Accidental Release Measures

Personal Precautions: Avoid generating dust. Use respiratory protection and gloves if required.
Spill Response: Sweep or vacuum material into marked containers for recovery or disposal. Damp down to avoid airborne particulates.
Environmental Precautions: Prevent runoff into drains, sewers, or natural waterways.
Clean-Up Methods: Clean area thoroughly after material pickup, using water if necessary. Ensure proper ventilation during clean-up.

7. Handling and Storage

Handling: Minimize dust generation. Use in a well-ventilated area. Avoid contact with eyes, skin, and clothing. Wash hands after use.
Storage: Store in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible substances. Protect from direct sunlight and heat sources.
Packaging Materials: Use polyethylene-lined containers. Avoid reacting containers with high moisture permeability.

8. Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation if dust develops during handling.
Personal Protective Equipment: Safety goggles, protective gloves, and lab coats recommended during processing.
Respiratory Protection: Use an approved dust mask in cases of insufficient ventilation.
Exposure Limits: No established OSHA, NIOSH, or ACGIH limits. Minimize exposure as part of good working practice.
Hygiene: Wash hands, face, and exposed skin before meals and after working. Avoid eating, drinking, and smoking in work areas. Clean protective equipment regularly.

9. Physical and Chemical Properties

Appearance: White to off-white, hygroscopic, odorless powder or granules
Odor: Odorless or mild
pH (1% solution): 5.5–7.5
Solubility: Freely soluble in water, insoluble in organic solvents like ethanol or acetone
Melting Point: Decomposes above 190°C
Boiling Point: Not relevant due to decomposition
Bulk Density: 0.4 – 0.8 g/mL
Vapor Pressure: Not applicable
Flash Point: Not applicable
Auto-ignition Temperature: Not established
Viscosity: Not applicable
Partition Coefficient: Not determined
Evaporation Rate: Not applicable

10. Stability and Reactivity

Chemical Stability: Chemically stable under normal temperatures and storage conditions
Reactivity: No dangerous reactions known under recommended use
Conditions to Avoid: Moisture, excessive heat, sources of ignition
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Sulfur oxides, carbon monoxide, carbon dioxide, and other irritating fumes if exposed to fire or extreme heat

11. Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): >5000 mg/kg (low acute toxicity)
Skin Corrosion/Irritation: Not expected based on available data
Serious Eye Damage/Irritation: Dust may cause mild irritation
Respiratory Sensitization: Prolonged exposure to dust can cause discomfort
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity: No evidence for mutagenic effects
Reproductive Toxicity: No significant evidence in published toxicity data
Chronic Effects: Prolonged or repeated exposure not expected to produce significant effects based on normal use

12. Ecological Information

Ecotoxicity: No known harmful effects to aquatic or terrestrial life at typical concentrations
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Low, does not bioaccumulate
Mobility in Soil: Due to high solubility in water, may leach into groundwater in large quantities
Other adverse effects: Not classified as hazardous for the environment

13. Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, regional, and national regulations
Small Quantities: May be disposed of with normal waste if allowed by regulations
Contaminated Packaging: Clean containers before reuse or recycle. Puncture and render unusable if intended for disposal.
Precautions: Prevent uncontrolled spillage into drains or natural environments. Do not discharge large quantities into sewers.

14. Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not considered dangerous for transport under ADR, IATA, IMDG, RID
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Transport Precautions: Ensure containers are tightly sealed. Protect from direct sunlight, moisture, and physical damage during transit.

15. Regulatory Information

Regulatory Status: Not regulated under US TSCA, EU REACH exemptions apply for naturally derived products
Inventory Listings: Registered in various national chemical inventories
Labeling Requirements: Non-hazardous, no special labeling required under OSHA or CLP
Other Regulations: Product is allowed for use in dietary supplements following quality and purity standards. Not subject to SARA Title III Section 313 reporting.
Workplace Controls: General workplace safety procedures for dust handling apply, including routine ventilation and proper storage arrangements