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West Ujimqin Banner, Xilingol League, Inner Mongolia, China
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Product Name: Sialic Acid
Chemical Name: N-Acetylneuraminic Acid
Chemical Formula: C11H19NO9
CAS Number: 131-48-6
Synonyms: NANA, Neu5Ac
Recommended Use: Research, biochemical assays, pharmaceutical ingredient
Supplier Details: Refer to packaging or purchasing documentation for responsible entity address and emergency contacts
Classification: Not classified as hazardous under GHS/OSHA (as of the latest available data)
Hazard Statements: May cause skin or eye irritation on direct contact or prolonged exposure; dust may cause mild respiratory irritation
Pictogram: No pictogram assigned
Precautionary Statements: Avoid dust generation; use adequate ventilation; wear recommended personal protection
Signal Word: Caution
Other Hazards: Potential allergic response in sensitive individuals
Component: Sialic Acid
Chemical Formula: C11H19NO9
Concentration: ≥98% (by weight)
Impurities: Trace solvents, water, residual reactants based on manufacturing process
Inhalation: Remove affected individual to fresh air; if symptoms such as coughing or difficulty breathing develop, seek medical attention
Skin Contact: Remove contaminated clothing and rinse skin with water and mild soap for 20 minutes
Eye Contact: Rinse eyes under gentle running water for at least 15 minutes, lifting eyelids; seek medical attention if irritation persists
Ingestion: Rinse mouth thoroughly; drink water if conscious; seek advice from poison control or a medical professional for large exposures or if symptoms develop
Most Important Symptoms: Mild irritation, redness, or dryness on skin and eyes; irritation of upper respiratory tract. Individuals with allergies may have stronger symptoms
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: High-pressure water jet
Specific Hazards: May decompose under fire conditions producing toxic gases such as nitrogen oxides or carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Precautions for Firefighters: Move containers away from fire area if safe; keep surroundings cooled with water
Personal Precautions: Use gloves, safety goggles, and a dust mask to avoid inhalation or skin contact; ensure adequate ventilation
Environmental Precautions: Prevent product from entering drains, soil, or waterways
Methods for Cleanup: Sweep or vacuum up material without raising dust; transfer to closed container for disposal; wipe area with damp cloth if necessary
Notification Procedures: Report spills to responsible authorities as required by local regulations
Handling: Work with product in a ventilated area; avoid direct contact with skin and eyes; avoid breathing dust; wash hands thoroughly after use
Storage: Store in sealed container away from moisture, heat, and direct sunlight; keep in a cool, dry, well-ventilated location
Incompatible Materials: Strong oxidizing agents, moisture, strong acids or bases
Hygiene Measures: Do not eat, drink, or smoke during handling; ensure good laboratory practices to prevent contamination
Exposure Limits: No established occupational exposure limits (consult local guidelines for dust limits)
Engineering Controls: Use chemical fume hood or local exhaust ventilation to reduce airborne concentrations
Personal Protective Equipment: Nitrile gloves, safety goggles, laboratory coat
Respiratory Protection: Dust mask or NIOSH-approved respirator when airborne concentration is excessive or during cleanup to prevent inhalation
Environmental Controls: Use spill-proof storage and handling equipment to avoid release into environment
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: Typically acidic in aqueous solution (pH 2–4 at 1% w/v)
Melting Point: 162 – 165 °C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Freely soluble in water; slightly soluble in ethanol
Vapor Pressure: Not determined
Density: Approximately 1.68 g/cm³
Partition Coefficient (n-octanol/water): Not determined
Flash Point: Not flammable
Evaporation Rate: Not applicable
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 160°C
Viscosity: Not applicable for solid
Molecular Weight: 309.27 g/mol
Stability: Stable under recommended storage and handling conditions
Reactivity: No known hazardous reactions under normal conditions
Conditions to Avoid: Excessive heat, moisture, strong oxidizing materials
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide may develop if combusted or decomposed at high temperatures
Acute Toxicity: Low toxicity based on available animal and in vitro studies; LD50 not determined for humans through oral or dermal routes
Skin Corrosion/Irritation: Mild irritation possible on prolonged or repeated contact
Serious Eye Damage/Irritation: May cause irritation with redness or tearing; effects usually reversible
Respiratory Sensitization: Possible irritation from dust inhalation; insufficient data to conclude sensitization
Skin Sensitization: No known cases of sensitization documented, but allergic reactions can occur
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity/Genotoxicity: No evidence found in standard tests
Reproductive Toxicity: No evidence from available data of harm to reproductive health
Target Organ Effects: No widely documented organ-specific toxicities for chronic or acute exposures
Potential Health Effects: Irritation of respiratory tract, skin, or eyes in sensitive individuals or high dust environments
Ecotoxicity: Not expected to be harmful to aquatic or terrestrial life at normal environmental concentrations based on structure and use patterns
Persistence and Degradability: Biodegradable under ambient environmental conditions
Bioaccumulation: Low potential for accumulation in aquatic organisms; log Kow low or not measurable
Mobility in Soil: Highly soluble in water; likely to be mobile in moist soils, potentially reaching surface water
Other Adverse Effects: Data gaps exist for chronic exposure in complex ecosystems, but no significant impacts expected from research or laboratory quantities
Disposal Methods: Contact local waste management authority for guidance; recommended to incinerate or dispose of as non-hazardous chemical waste if allowed
Contaminated Packaging: Rinse with water and dispose of according to regulations; incinerate or landfill if permitted and safe
Precautions: Prevent disposal of significant quantities in drains, watercourses, or soil to avoid localized pollution; do not reuse empty containers without cleaning
UN Number: Not regulated as a dangerous good for transport by road, rail, sea, or air
Proper Shipping Name: Sialic Acid
Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: Not classed as environmentally hazardous for transport
Special Precautions: Pack product tightly in sealed containers; avoid conditions that generate dust; label and document as laboratory chemical
OSHA Status: Not specifically regulated
TSCA Inventory: Listed
EC Inventory (EINECS): Listed: 205-023-6
REACH Registration: Exempt or not required for small quantities for research
WHMIS (Canada): Not classified as hazardous
Other Regulations: ADR, RID, IMDG, IATA/ICAO do not designate sialic acid as hazardous or special cargo
Right to Know: Not listed on California Proposition 65 or similar state hazard lists
National Chemical Inventories: Present in several international databases; check supplier-specific certifications for detailed compliance
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
