Safflower has grown in fields for more than a thousand years, tracing roots back to ancient Egypt and China. Folks boiled down the petals, gathered the color. Ancient texts show dyed cloth and medicinal drinks. Over time, trade routes carried these golden blooms west, and different regions experimented with dyes and remedies. Science started catching up in the twentieth century, pushing safflower from folk craft into the industrial and pharmaceutical labs. The story of safflower yellow connects cultures, and each generation has found new ways to tap into its properties. Today, both small farmers and biochemistry researchers see value in this old, striking yellow extract.
Safflower yellow comes from petals and carries that strong, orange-gold pigment many people see in specialty teas and cosmetics. Some producers pack it as a powder, others concentrate it into a liquid. This colorant shows up in food labels as E164 or in herbal medicines listed as carthamin. It stands out for its plant-based origin, making it one of the preferred natural dyes. Some companies highlight that it doesn’t come from animals or synthetic chemicals, appealing to brands aiming for cleaner, more sustainable labels. Often, the extract contains a mixture of carthamin and other minor compounds, offering both color and some antioxidant properties in certain products.
Anyone handling pure safflower yellow sees a bright, reddish-yellow, fine powder, usually light enough to drift in the air. It dissolves best in alcohol and water, less so in oils. Chemically, the main pigment is called carthamin, a complex flavonoid structure with two glucose parts giving a unique solubility profile and chemical behavior. It melts at relatively high temperatures, and the color holds up under mild heat and a variety of pH levels. High exposure to strong acids or bases fades color intensity. Safflower yellow also shows some sensitivity to light, so packaging needs to keep out sunlight.
Every industry wants details. In food production, safflower yellow powder typically measures above 95% purity, balancing moisture content under 6%. Color strength gets measured by absorbance at a certain wavelength (usually 450 nm). Labels on commercial products need to state purity, origin (plant-derived), any solvents used in extraction, and compliance with regulatory limits on contaminants, like heavy metals or pesticides. Finished food items with safflower yellow as a colorant must include it in the ingredients list, often mentioning the INCI or E-number, giving consumers a clear picture. Dietary supplements using it tend to highlight its source and content per capsule or cup.
Harvesting starts early in the morning, picking petals before sun and wind dry out the color. After collection, petals steep in water or alcohol to release pigments. Commercial facilities may run these solutions through filters and rotary evaporators, concentrating the color. Older methods left some impurities, but modern processes improve purity through careful solvent selection and additional steps like precipitation, followed by gentle drying. Some factories standardize color strength by blending different lots to hit specification targets. Safety checks scan for residues, microbes, and heavy metals before packaging.
Carthamin, the core molecule in safflower yellow, can undergo chemical changes. By reacting the pigment with sulfites or adjusting pH, the hue can shift slightly, allowing broader uses in foods or textiles. Some labs tweak extraction pH to draw out new variants or improve yield, producing salt forms that mix better in cold drinks. Enzymes applied during treatment might open new compounds with altered antioxidant activity. Research teams also explore how simple sugar attachments or acid treatment create modified molecules for unique shades or stronger stability when added to processed foods or beverages.
Safflower yellow goes by several names in trade and science. Carthamin stands as its chemical name. The colorant lists as E164 in the European food code and is sometimes called natural yellow 3. In the world of cosmetics, International Nomenclature of Cosmetic Ingredients (INCI) registers it under Carthamus Tinctorius Flower Extract. Traditional medicine shops label it as “Honghua” in China. With all these aliases, the key stays in clear communication so buyers know what’s in the box.
Factories and workers deal with safflower yellow following strict rules. International standards, such as those laid out by the Food and Agriculture Organization (FAO) and World Health Organization (WHO), put limits on microbial contamination, solvents, and heavy metals. Producers enforce Good Manufacturing Practices (GMP), handling raw petals with gloves and masks, washing equipment after each use. Regular testing screens every lot. Workers wear protective equipment, especially since the fine powder floats easily and can irritate airways. Companies track each batch from field to shelf, keeping records for traceability if questions come up during inspection.
Food companies tap safflower yellow for drinks, candies, noodles, and salad dressings where a natural label matters. Herbal medicine blends rely on its mild color and claimed antioxidant properties. Cosmetic brands like to add the extract to lipsticks, blushes, and hair conditioners. Textile crafters enjoy its historic roots in yarn and fabric dyes. Safflower yellow even turns up in artist pigments, paper products, and a few specialty plastics. Functional food startups experiment with safflower yellow as a label-friendly antioxidant, feeding consumer demand for plant-based ingredients.
Universities and research labs focus on boosting extraction yields and isolating minor pigments for health products. Work in chromatography and molecular analysis seeks to separate flavonoids, carotenoids, and other active fractions for deeper study. Teams test new solvents, modified enzymes, and clean energy heating to improve sustainability. Scientists look at how changes in petal genetics or growing conditions shift pigment profiles. Companies sponsor clinical studies on how different extracts affect blood pressure, inflammation, or cholesterol. Preclinical research tries to sort out which bioactive molecules show the strongest health benefits, hoping to develop unique patents and new supplements.
Researchers spend time checking for side effects and toxic reactions. Tests on animals and cell cultures after oral and topical use show low toxicity for standard doses, and food safety agencies in Europe and Asia approve safflower yellow at regulated levels. Scientists keep an eye on long-term effects with chronic intake, but so far, no strong links point to risk at common dietary exposures. Some allergies can appear in those sensitive to safflower or related plants. Unknowns still exist for interaction with certain medications or in large, therapeutic doses. Toxicologists call for ongoing studies as extraction methods get more concentrated, reminding both producers and policymakers to support fresh safety research.
Demand keeps rising for natural colors as regulators tighten limits on synthetics. More companies look to safflower yellow for clean-label foods, herbal capsules, and eco-friendly colorants. Next steps may involve bioengineering safflower plants for higher pigment yield and more robust color. Researchers hunt for stronger antioxidant properties and explore possible heart-protective or anti-inflammatory effects. Some biotechnologists experiment with microbial fermentation or in vitro cultivation of safflower cell lines, aiming for pigment production with a lower resource footprint. As public interest grows in plant-based diets, manufacturers emphasize safflower yellow’s non-GMO status and minimal processing. Future breakthroughs could come from better storage, travel packaging, or entirely new uses in medicine and material science.
Safflower yellow comes from the dried petals of the safflower plant. Some people would be surprised by just how much of this golden pigment ends up on dinner tables and in traditional medicine cabinets. I still remember my grandmother’s kitchen, bright red-orange threads steeped in hot water, tinting soups and stews to a sunny yellow. Food is only one piece of the story, though.
Most shoppers meet safflower yellow in the grocery aisle, hidden behind E-code labels or listed as a natural color. Bakeries use it to brighten up frosting and cakes. Some companies sneak it into soda or fruit drinks to balance out an uneven hue. It’s not just about the look—a familiar color helps people trust what’s in their glass. I’ve seen chefs use it to get that golden tone for rice dishes or dumplings without changing the flavor, which can be a game-changer in recipes where color matters but taste stays delicate.
Safflower yellow holds particular importance in regions like East Asia and the Middle East. In many traditional sweets or staple dishes, artificial dyes stand out as alien. Some parents worry about safety, so they steer toward natural pigments. According to regulatory reviews, safflower yellow carries a long track record of safe use as a food additive, standing apart from synthetic alternatives that can raise health concerns.
Step outside the kitchen, and safflower yellow blends into herbal medicine. Practitioners in Traditional Chinese Medicine have valued it for centuries. People believe it promotes blood flow and helps manage pain. Researchers today have started testing these beliefs with modern methods, and preliminary studies point to antioxidant and anti-inflammatory properties, which fits with its traditional role. Still, shoppers need to stay informed and wary of exaggerated health claims since not every old remedy stands up to scientific scrutiny.
The pigment reaches even further. Textile craftspeople and artists use safflower yellow for dyeing fabrics and painting. Its golden shade lasts well on cotton and silk, holding a place in natural dye palettes. Years ago, I helped a friend tie-dye silk scarves, and safflower gave the fabric a mellow warmth that synthetic yellows just couldn’t match. It’s this promise of authenticity and safety that keeps creative communities coming back to it, particularly in times when there’s growing concern over the chemicals involved in fast fashion.
Safflower yellow brings color without synthetic additives, but consistency depends on the season and the soil where safflower grows. Farmers and manufacturers sometimes face challenges as they balance demand for natural colors against cost and yield. Adulteration and mislabeling can slip in, prompted by the marketplace’s hunger for “all-natural” claims. People can push back by checking product sourcing and favoring brands with transparent ingredient lists and third-party testing.
Safflower yellow highlights the way old knowledge and modern living can meet. Its story ties together people around the world—home cooks, textile workers, family doctors. The next time yellow shines from a plate or a piece of cloth, take a second look. Natural color touches daily life, and choosing carefully, with a bit of skepticism and local know-how, invites something genuine onto our tables and into our traditions.
Supermarkets sell shelves of snacks and drinks showing off their glowing yellow and orange tints. Most folks probably never notice the label mentioning “Safflower Yellow.” As someone who reads ingredient lists on everything from pickles to popsicles, that line always sticks out. Safflower Yellow doesn’t fall into the same conversation as the much-debated artificial dyes, but folks still want to know what it brings to their table—especially as conversations around food coloring shift and parents keep an eye on what their families eat.
Safflower Yellow comes straight from the petals of the safflower plant—an ancient crop, growing in places like China, India, and the Middle East for centuries. The safflower’s main gig used to be oil production and natural dye for clothes, but food producers began using its yellow extract for meals that needed a pop of color. Chemists call it “Natural Yellow 6,” distinct from synthetic dyes like tartrazine (Yellow 5).
Research teams and food safety agencies approach dyes with careful scrutiny. Authorities including the U.S. Food and Drug Administration (FDA), the European Food Safety Authority (EFSA), and China’s National Health Commission have all reviewed safflower yellow. Current data shows it breaks down easily in the body and gets flushed out pretty fast. Multiple animal studies find no strong evidence for any serious adverse effects, even at doses much higher than people usually eat. EFSA set a safe intake level at 5 mg per kilogram of body weight each day, a limit most people never reach unless they treat themselves to gallons of artificially colored drinks every afternoon.
I remember a school science project comparing reactions to various food colors—friends with sensitivities to synthetic dyes had flare-ups, but natural colors like safflower yellow didn’t set them off. Components in safflower, like carthamidin and carthamin, don’t appear to trigger allergies or hyperactivity at the levels added to candy, pastries, or beverages.
Still, not every batch of safflower-derived dye is trouble-free. Some reports show food makers outside regulated markets may cut corners and add unauthorized additives to boost color yield. Quality control matters. If you buy foods directly imported from countries with lax enforcement, the risk of adulteration remains.
Heavy metals sometimes sneak into poorly processed extracts. A report out of Hong Kong’s Centre for Food Safety once flagged some imported safflower products containing lead above safe limits. That’s not a danger tied to the safflower plant itself—but to sloppy manufacturing practices.
Picking brands that share test results or certifications goes a long way in sidestepping tainted products. I always go for snacks with ingredients sourced from countries where regulatory agencies check batches before sale. Food makers following good manufacturing standards test for metals and pesticides, post their findings, and keep contaminants in check. Busy parents and cautious eaters deserve that peace of mind.
More folks today cut out artificial additives or shop for cleaner labels. As safflower yellow keeps finding its way into noodles, baked goods, milk drinks, and even vitamins, shoppers need easy-to-understand info and honest labeling. Regulators should tighten import checks and set specific contaminant thresholds. Reliable, regular testing gives families and schools more confidence that what they put on plates is as safe as it is appetizing.
Safflower yellow comes from the safflower plant, a crop that’s been around for centuries. Many folks recognize safflower as a common cooking oil, but Safflower Yellow dyes every bit as much history as those golden bottles on grocery shelves. In Asian cuisine, textiles, and even in traditional medicine, this yellow coloring matters for more than its looks. Safflower petals serve as the starting point. Nobody gets Safflower Yellow without harvesting these bright, dried petals.
The star player here is carthamin. Chemically, carthamin is responsible for that deep yellow hue found in everything from fancy bakery icing to festive fabrics. Safflower petals contain both carthamin and a less vivid pigment called safflor yellow A (often called precarthamine before extraction). Both compounds fall under the umbrella of natural flavonoids, a family of plant chemicals tied to color and sometimes even health perks. Carthamin not only brings color, but research from food chemistry journals points toward antioxidant properties.
Take a handful of dried safflower petals and there’s a lot more than just pretty coloring in the mix. There’s protein, traces of fat, fiber, and a cocktail of natural plant compounds, but only a small piece delivers the high-purity pigment. Safflower Yellow that winds up in food coloring and textiles goes through water extraction and filtration processes to pull out carthamin and related yellow pigments. For every kilo of petals, expect only a few grams of edible coloring agent.
Quality products make sure to avoid contamination from heavy metals and pesticide residues, which sometimes show up if farmers spray too much. Poor-quality safflower extracts can contribute to health risks rather than health benefits.
Plenty of folks use food coloring, but awareness about what those colors contain lags behind. Synthetic food dyes have long raised concerns about allergies, risky additives, and even child hyperactivity. Safflower Yellow stands out as a natural alternative, free from tartrazine and other synthetic yellow dyes that can spark reactions in sensitive people.
From my own kitchen, I always check food labels for coloring sources. Safflower Yellow feels safer and more wholesome because it comes from petals rather than a lab process. Beyond that, safflower dyes don’t just tint foods — they color traditional robes and festival banners in Asia. In herbal medicine, carthamin even gets discussed for anti-inflammatory benefits, though common sense says don’t swap this for your prescriptions without evidence.
Natural coloring from safflower petals could help more people cut down on artificial ingredients. As interest in clean-label foods keeps rising, food scientists and growers face the challenge of reliable sourcing and extraction. Product purity depends on careful farming and thorough lab testing. Some producers try to stretch safflower extracts with blends of cheap fillers, which cheats consumers and poses unknown risks.
The future may rest on tighter regulations and more transparent labeling. One way forward could involve traceable supply chains and certification, similar to what’s happened with fair trade coffee and organic produce. If you’re looking for Safflower Yellow in your dinner, pressing for ingredient transparency protects everyone’s well-being.
Safflower yellow pops up often in food and herbal teas across Asia, especially in China. It draws its color from the Carthamus tinctorius plant, also known as safflower. For centuries, the pigment helped bakers brighten buns, doctors brew herbal remedies, and cooks liven up a plate. A splash of warm yellow feels harmless, maybe even old-fashioned. Still, with so many modern foods stuffed with colors and additives for shelf life or visual appeal, people start to ask: does safflower yellow do any harm?
Years ago, learning to cook with my grandmother meant learning to trust what I put on the plate. Safflower was always a kitchen staple. She said it soothed aches, lifted the spirit, and made stews beautiful. I never saw her get sick after eating safflower-infused food, and neither did I. But as times change, diets vary, and food processing gets more complicated, more people hope science will back up what tradition promises.
Safflower yellow contains compounds called flavonoids, mainly carthamin and safflor yellow A. Early lab studies say these compounds might cut inflammation and ease pain. Scientists keep digging into it for clues about whether the bright powder truly heals—or if it hides risks behind that sunny shade.Some clinical reports and toxicological studies shed a little light. Most research says the doses used in foods and drinks rarely spark trouble for healthy adults. Allergic reactions, headaches, and digestive upset come up, but not often. A handful of people might feel unwell, especially if they take massive amounts.
Data from China’s National Center for Food Safety Risk Assessment shows food colorings like this one get reviewed and measured. Regulators limit how much color goes in food to steer clear of toxicity. According to recent safety evaluations, safflower yellow’s acceptable daily intake sits at 0-0.7 milligrams per kilogram of body weight. That means a 70 kg adult could safely consume up to 49 mg a day on average, which goes way beyond a few drops in a sweet bun.
Kids, pregnant women, and people with allergies face the most questions. Children’s smaller bodies absorb more color by comparison, so any side effects show up faster. Women expecting a child should take care—some animal studies hint at possible effects during pregnancy, though human data is thin. People prone to allergies, especially those sensitive to pollen, should check labels. Like so many plant-based ingredients, safflower can cross-react for those with asthma or certain allergies.
Safflower yellow rarely causes dramatic reactions at the doses in food and tea, but uncertainty lingers. With so much herbal wisdom wrapped up in cultural food, the science ought to catch up with the daily reality. Not everyone wants to trawl through scientific papers, so clearer food labels and honest communication help more than grand claims on a label. Shoppers deserve easy access to allergy warnings, proven safety info, and plain facts about what’s in their snacks.
One easy fix: use safflower yellow as a treat, not an everyday ingredient, especially for those more likely to react. Doctors and nutritionists could stand to ask about traditional pigments, not just artificial dyes, in dietary checkups. Researchers might take more time to study plant-based colors under real-world conditions rather than lab doses far above what lands on a dinner table.Over time, better transparency and more data from both kitchens and clinics should help build trust. For now, long-standing tradition and scientific reviews mostly agree—safflower yellow brings more color than harm to the modern plate, but care and clear guidance matter for everyone’s peace of mind.
Safflower Yellow pops up in everything from traditional medicines to snacks and drinks. Recent years pulled this natural pigment out of specialty shops and into more homes and small businesses. In shops and pantries, it adds color and value, but it doesn’t last forever. Warm air and light turn powder or flakes stale, and once-dazzling orange fades into a dull shade. That hits the pocketbook and rattles consumer trust. I’ve had a batch go bad myself, and learned shortcuts don’t pay off. It’s easy to forget how quickly moisture and sunlight spoil dried plant materials.
Anyone who’s cracked open a spice jar after a year or two knows plant pigments don’t last in tough conditions. For Safflower Yellow, ultraviolet rays and oxygen attack the pigment molecules. Even the steadiest warehouse loses the fight if the pigment sits near a sunny window or in a humid storeroom. Steamed-up glass jars or plastic containers trap dampness, speed up clumping, and leave you with a ruined supply. That loss stings twice — less color, and, in some cases, lost functional properties. Studies in food science journals point out that color intensity drops fast at temperatures above 25°C and in high moisture.
In my home kitchen, I learned the hard way that a screw-top jar near the stove welcomes steam, and fragrance fades away in weeks. Now I keep safflower pigment on a high, dark shelf inside a sealed metal tin. If you’re storing larger amounts or run a business, food-grade poly bags or brown bottles block light. Vacuum sealing gives an extra layer of protection, sucking out oxygen so the color stays true for months. For even bigger stocks, climate-controlled shelves keep both temperature and humidity steady. Factories often aim for under 60% relative humidity, with storage rooms cool and dark.
Loose powders pick up smells from their neighbors. Last year, I stored some safflower beside dried garlic — big mistake! For stores and processing lines, space away from strongly scented foods keeps the color and flavor pure. FDA recommendations for all food storage apply here: dry hands, clean scoops, and sealed containers. Loose labeling or skipping rotation dates can lead to confusion. Always tag each batch with the arrival date, so older stocks go first. That simple habit cuts down on wasted inventory and keeps the product safe.
Even with airtight containers and climate control, it helps to check color and aroma every few weeks, especially in humid climates. Dull hues and musty smells hint at lost quality. Testing small samples saves a big batch from going to waste. If the pigment clumps, toss it — moisture in the container means a higher risk of spoilage microbes.
From my own experience and trusted science, good safflower pigment deserves thoughtful storage. Cool, dry, and dark conditions protect its color and keep it safe for foods, drinks, and natural medicines. Simple habits, like airtight sealing and regular checks, go a long way. Smart storage honors both the value of the ingredient and the safety of the people who use it.
| Names | |
| Preferred IUPAC name | (2E,2′E)-2,2′-(3,3′-Dioxo-1,1′-biindene-2,2′-diylidene)bis(3-oxoprop-1-enoic acid) |
| Other names |
Natural Yellow 5 CI Natural Yellow 5 Hydroxysafflor yellow Safflor Safflor yellow A Safflower yellow pigment Safflower extract |
| Pronunciation | /ˈsæf.laʊ.ər ˈjɛl.oʊ/ |
| Preferred IUPAC name | (2E,2′E)-3,3′-((3,3′-Dimethyl[1,1′-biphenyl]-4,4′-diyl)bis(oxy))bis(2-[(4-hydroxyphenyl)methylidene]-7-methyl-2,3-dihydro-1H-pyrrol-3-one) |
| Other names |
Carthamus Yellow Natural Yellow 5 CI Natural Yellow 5 Carthamus Tinctorius Yellow Hung Wong Kusum Yellow |
| Pronunciation | /ˈsæf.laʊ.ər ˈjɛl.oʊ/ |
| Identifiers | |
| CAS Number | CFDA 127-40-2 |
| Beilstein Reference | 2597936 |
| ChEBI | CHEBI:75127 |
| ChEMBL | CHEMBL3243838 |
| ChemSpider | 22230508 |
| DrugBank | DB15316 |
| ECHA InfoCard | 100.052.465 |
| EC Number | E105 |
| Gmelin Reference | 87892 |
| KEGG | C09747 |
| MeSH | D013165 |
| PubChem CID | 123154 |
| RTECS number | GZ3225000 |
| UNII | D31UA3GR0D |
| UN number | UN3155 |
| CompTox Dashboard (EPA) | DTXSID1039247 |
| CAS Number | 125355-02-4 |
| Beilstein Reference | 80528 |
| ChEBI | CHEBI:166722 |
| ChEMBL | CHEMBL3625459 |
| ChemSpider | 186476 |
| DrugBank | DB15872 |
| ECHA InfoCard | 100.020.176 |
| EC Number | E-164 |
| Gmelin Reference | 68440 |
| KEGG | C08606 |
| MeSH | D013467 |
| PubChem CID | 5282296 |
| RTECS number | WW7000000 |
| UNII | 04JA59P8WL |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DTXSID1021378 |
| Properties | |
| Chemical formula | C24H20O11 |
| Molar mass | 1203.26 g/mol |
| Appearance | Yellow to brownish yellow powder |
| Odor | Odorless |
| Density | 0.7–0.9 g/cm³ |
| Solubility in water | Soluble in water |
| log P | 1.95 |
| Acidity (pKa) | 10.24 |
| Basicity (pKb) | 10.77 |
| Magnetic susceptibility (χ) | -73.0e-6 cm^3/mol |
| Refractive index (nD) | 1.595 |
| Viscosity | Viscous liquid or semi-solid |
| Dipole moment | 3.6107 D |
| Chemical formula | C24H20O11 |
| Molar mass | Molar mass: 990.86 g/mol |
| Appearance | Yellow powder or granules |
| Odor | Odorless |
| Density | 0.64 g/cm³ |
| Solubility in water | Soluble in water |
| log P | 1.21 |
| Acidity (pKa) | 10.71 |
| Basicity (pKb) | 11.48 |
| Refractive index (nD) | 1.566 |
| Dipole moment | 5.75 ± 1.0 D |
| Pharmacology | |
| ATC code | A16AX13 |
| ATC code | A16AX12 |
| Hazards | |
| Main hazards | May cause respiratory irritation. |
| GHS labelling | GHS07, GHS09 |
| Pictograms | GHS07, GHS09 |
| Signal word | Warning |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P264, P270, P273, P301+P312, P330, P501 |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | 87.6°C |
| Autoignition temperature | 400°C |
| Lethal dose or concentration | LD₅₀(mouse, intravenous): 104 mg/kg |
| LD50 (median dose) | LD50 (median dose) of Safflower Yellow: 2.12 g/kg (mouse, orally) |
| NIOSH | RN 11116-54-0 |
| PEL (Permissible) | 10 mg/m³ |
| REL (Recommended) | 10 mg/kg |
| Main hazards | Harmful if swallowed, causes skin and eye irritation. |
| GHS labelling | GHS07, GHS09 |
| Pictograms | GHS07, GHS09 |
| Signal word | Warning |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P264, P270, P273, P301+P312, P330, P501 |
| Flash point | >100°C |
| Autoignition temperature | 400°C |
| Lethal dose or concentration | LD₅₀(mouse, oral): 12.4 g/kg |
| LD50 (median dose) | LD50 (median dose): >1,679 mg/kg (mouse, intravenous) |
| NIOSH | WX9R25818J |
| PEL (Permissible) | 200 mg/kg |
| REL (Recommended) | 100 mg/kg |
| Related compounds | |
| Related compounds |
Carthamin Quercetin Flavonoids Safflower Red Safflor yellow A Safflor yellow B |
| Related compounds |
Quercetin Safflor yellow A Safflor yellow B |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 365.3 J·mol⁻¹·K⁻¹ |