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Product Name: Riboflavin Chemical Name: 7,8-dimethyl-10-ribityl-isoalloxazine Common Names: Vitamin B2 CAS Number: 83-88-5 Manufacturer: Commonly produced by chemical and pharmaceutical companies globally Recommended Use: Used as a nutritional supplement, food additive, and in pharmaceutical preparations Contact Information for Supplier: Provided on actual product packaging
GHS Classification: Not classified as hazardous based on available information Signal Word: None required Hazard Statements: No significant health hazards identified under normal use. Dust may cause mild respiratory irritation in sensitive individuals. Prolonged exposure to dust can cause dryness in skin and eyes. Pictograms: No symbol required Precautionary Statements: Avoid inhalation of dust. Use in a well-ventilated area. If skin or eye irritation occurs, rinse thoroughly.
Chemical: Riboflavin Purity: Typically >98% Formula: C17H20N4O6 Molecular Weight: 376.36 g/mol Impurities: Manufacturer-specific minor organic or inorganic materials
Eye Contact: Immediately rinse eyes with lukewarm water for at least 15 minutes. Remove contact lenses if present. Seek medical attention if irritation persists. Skin Contact: Wash skin with soap and water. Remove contaminated clothing and shoes. Medical help is necessary for persistent irritation. Inhalation: Move person to fresh air. Provide oxygen if breathing is difficult. Get medical help in severe cases. Ingestion: Rinse mouth with water. Do not induce vomiting. If any discomfort occurs, get medical attention. Notes for Physicians: Treatment based on symptoms; no specific antidote known.
Suitable Extinguishing Media: Use water spray, dry chemical, CO2, or foam Specific Hazards Arising from the Substance: Dust can form explosive mixtures in air. Combustion may produce carbon oxides, nitrogen oxides Protective Equipment and Precautions for Firefighters: Use full protective gear including self-contained breathing apparatus Thermal Decomposition: Yields toxic fumes upon burning Firefighting Guidance: Cool containers with water spray to prevent rupture from heat.
Personal Precautions: Avoid inhalation, provide ventilation, and wear dust masks and protective gloves Environmental Precautions: Prevent release to drains, soil, and surface water Methods for Cleaning Up: Sweep or scoop up spilled material, avoiding dust formation. Place in suitable containers for disposal. Decontamination: Wash affected area with water after cleanup.
Handling: Avoid generation of dust. Use with local exhaust ventilation. Avoid contact with eyes, skin, or clothing. Avoid inhaling dust. Safe Storage Conditions: Store in a tightly closed container, in a cool, dry, well-ventilated area. Protect from light due to its photosensitivity. Keep away from strong oxidizers and incompatible materials. Hygiene Measures: Wash hands thoroughly after handling. Do not eat, drink, or smoke when using material.
Exposure Limits: No exposure limits established by OSHA, ACGIH Engineering Controls: Use process enclosures, local exhaust ventilation, or other controls to keep air levels below exposure guidelines Respiratory Protection: Dust mask or respirator recommended for dusty conditions Skin Protection: Chemical resistant gloves recommended Eye Protection: Safety glasses or chemical splash goggles Other Protection: Laboratory coat and eye wash station available nearby
Appearance: Orange-yellow crystalline powder Odor: Odorless Solubility: Slightly soluble in water; soluble in dilute alkali Melting Point: 280°C (with decomposition) Boiling Point: Decomposes before boiling pH: Approximately 5.0–7.0 (1% aqueous suspension) Flash Point: Not applicable Auto-Ignition Temperature: Not readily available Vapor Pressure: Not applicable Density: About 1.65 g/cm³ Partition Coefficient (log Kow): -1.46
Chemical Stability: Stable under recommended storage conditions, but breaks down with exposure to light Reactivity: Not reactive under normal conditions Conditions to Avoid: Excessive heat, exposure to light, and incompatible materials Incompatible Materials: Strong oxidizing agents, strong acids, base Hazardous Decomposition Products: May yield carbon monoxide, carbon dioxide, nitrogen oxides under fire conditions
Acute Toxicity: LD50 (oral, rat) >10,000 mg/kg; considered non-toxic for normal handling Potential Health Effects: Inhalation may irritate respiratory system. Contact with skin or eyes may induce mild irritation. Ingestion of large amounts can cause gastrointestinal discomfort Chronic Toxicity: Not classified as carcinogenic, teratogenic, or mutagenic Sensitization: Not known to cause allergic reactions Signs and Symptoms of Overexposure: Headache, nausea, dry skin, mild respiratory effects
Ecotoxicity: Not expected to be hazardous to aquatic life at typical environmental concentrations Persistence and Degradability: Readily biodegradable by soil and water microorganisms Bioaccumulative Potential: Low; riboflavin does not accumulate in organisms Mobility in Soil: Low mobility—binds to soil particles Other Adverse Effects: No known significant environmental effects reported
Waste Disposal Methods: Dispose in accordance with local, regional, and national regulations. Avoid discharge to sewers or natural waters. Incineration or landfill in approved facility as per regulatory requirements Container Disposal: Empty containers must be triple-rinsed and then offered for recycling or disposal in covered, labeled waste bins Special Considerations: Use personal protective equipment during cleanup and disposal
UN Number: Not regulated UN Proper Shipping Name: Not classified as a dangerous good Transport Hazard Class(es): Not applicable Packing Group: Not applicable Environmental Hazards: None known Special Precautions for User: Handle with routine care during transport, especially to avoid dust release and contamination
OSHA Status: Not listed as hazardous TSCA Inventory: Riboflavin appears on the US Toxic Substances Control Act (TSCA) inventory REACH Registration: Registered in the European Union under REACH DSL/NDSL (Canada): Listed SARA Title III: Not subject to reporting under Sections 302, 304, 311, 312, or 313 California Proposition 65: Not listed Labeling Requirements: Standard chemical labeling for non-hazardous substances Other Specific Regulations: Check national and local regulations for use in food, pharmaceuticals, and animal feed
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
