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Product Name: Pyridoxine Hydrochloride
Chemical Name: 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride
Common Name: Vitamin B6 hydrochloride
CAS Number: 58-56-0
Synonyms: Vitamin B6, Pyridoxine HCl
Recommended Use: Dietary supplement, pharmaceutical ingredient, feed additive
Supplier Information: Manufacturer’s address and emergency contact phone number should be clearly stated on packaging or upon request by regulatory officials
Classification: Not classified as hazardous according to OSHA Hazard Communication Standard (29 CFR 1910.1200)
Label Elements: No pictogram or signal word required under GHS
Potential Health Effects: May cause mild eye and skin irritation in sensitive individuals, inhalation of dust may irritate the respiratory tract, ingestion of excessive amounts could lead to sensory neuropathy and other neurological effects in rare cases
Environmental Hazards: Low risk to aquatic and terrestrial organisms
Other Hazards: Dust can accumulate and create a nuisance; risk of slipping if spillage occurs on smooth surfaces
Substance: Single ingredient
Chemical Name: Pyridoxine Hydrochloride
Concentration: ≥ 98% by weight
Impurities: Trace amounts of related compounds below regulatory concern
Molecular Formula: C8H11NO3•HCl
Molecular Weight: 205.64 g/mol
Inhalation: Remove affected person from exposure area to fresh air, provide oxygen or artificial respiration if breathing is difficult, seek medical advice if symptoms persist
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing and wash before reuse, seek medical attention if irritation occurs
Eye Contact: Rinse immediately with water for at least 15 minutes, lifting eyelids occasionally, consult a physician if symptoms persist
Ingestion: Rinse mouth with water, give water to drink if the person is conscious, contact poison control or seek medical attention if large amounts were swallowed or if symptoms appear
Most important symptoms: Local irritation at contact sites, rare risk of neurological symptoms after significant repeated exposure
Suitable Extinguishing Media: Use water spray, carbon dioxide, foam, or dry chemical to extinguish
Unsuitable Media: Do not use water jet as it may spread the product
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen chloride fumes
Fire Fighting Instructions: Firefighters should wear full protective clothing and a self-contained breathing apparatus to prevent exposure to gases and particulates released in a fire
Special Hazards: Fine dust may present an explosion hazard if suspended in air in sufficient concentration under certain conditions
Personal Precautions: Avoid creation and inhalation of dust, ventilate the area, discharge sources of ignition, wear suitable protective equipment including gloves, goggles, and dust mask
Environmental Precautions: Prevent large amounts from entering drains, sewers, or watercourses.
Spill Cleanup Methods: Sweep up material carefully, avoid raising dust, place in suitable, labeled containers for disposal, wash spill site thoroughly
Handling Precautions: Avoid contact with skin and eyes, prevent dust formation, use only with adequate ventilation, wash hands before eating or drinking
Storage Conditions: Store in a cool, dry, well-ventilated area, away from direct sunlight, heat, and sources of ignition, keep container tightly closed
Incompatible Materials: Strong oxidizing agents, acids, and bases may react with pyridoxine hydrochloride
Special Requirements: Do not store with food or feed, label all storage containers appropriately, practice good hygiene in handling area
Exposure Limits: No occupational exposure limit values established by OSHA, ACGIH, or NIOSH for pyridoxine hydrochloride
Engineering Controls: Use local exhaust ventilation, maintain airborne concentrations below nuisance dust limits of 10 mg/m³ (for total inhalable dust)
Personal Protective Equipment: Safety glasses with side shields, impervious gloves, lab coat or other appropriate protective clothing, NIOSH-approved dust respirator if dusting occurs
Hygiene Measures: Wash hands before eating, drinking, or smoking, remove and clean contaminated clothing before reuse, keep work area clean and dust-free
Appearance: White or nearly white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 2.0–3.0 (1% solution)
Melting Point/Freezing Point: 206–208°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Evaporation Rate: Not applicable
Flammability: Not flammable in bulk
Explosion Limits: No data (dust explosion risk if finely divided and dispersed)
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: Approximately 1.61 g/cm³
Solubility: Freely soluble in water, sparingly soluble in ethanol
Partition Coefficient (n-octanol/water): Log Pow: -1.11
Auto-ignition Temperature: No data
Decomposition Temperature: Begins to decompose at about 206°C
Viscosity: Not applicable
Chemical Stability: Stable under normal conditions if properly stored
Conditions to Avoid: Moisture, excessive heat, exposure to direct sunlight
Incompatible Materials: Strong oxidizers, strong acids and bases
Hazardous Decomposition Products: Thermal decomposition can yield toxic fumes such as carbon oxides, nitrogen oxides, hydrogen chloride
Hazardous Reactions: No known hazardous polymerization
Reactivity: Low reactivity, avoid mixing with incompatible materials to prevent potential reaction hazards
Acute Toxicity: Oral LD50 in rats > 3000 mg/kg (low toxicity)
Chronic Effects: High or prolonged dosing in humans can cause sensory neuropathy and ataxia, which is rare under normal use
Skin and Eye Contact: Mild, transient irritant potential
Inhalation: Dust may irritate the upper respiratory tract
Sensitization: Not known to cause skin sensitization
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, OSHA
Mutagenicity: Negative in standard in vitro and in vivo mutagenicity tests
Reproductive Toxicity: No evidence of reproductive toxicity at standard exposure levels
Acute Aquatic Toxicity: Not expected to be harmful to aquatic life in standard environmental concentrations
Persistence and Degradability: Readily biodegradable in the environment through microbial action
Bioaccumulation Potential: Low, based on Log Pow and rapid degradation
Mobility in Soil: High solubility in water, moderate mobility expected
Other Adverse Effects: No evidence of significant ecological hazards under normal usage and disposal practices
Waste Disposal Methods: Dispose of in accordance with local regulations, unused material may be handled as non-hazardous chemical waste
Container Disposal: Rinse empty containers with water, recycle plastic or cardboard, incinerate as allowed or send to approved landfill
Environmental Precautions: Do not release significant amounts to sewage systems, surface or ground water
Special Notes: Consider waste minimization and recycling alternatives; seek advice from local waste authorities for best practices
UN Number: Not classified as dangerous goods under UN transport regulations
Proper Shipping Name: Pyridoxine Hydrochloride
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Labels Required: None
Environmental Hazards: None identified
Special Precautions: Protect from humidity, handle in containers that prevent dust release during transport
Regulatory Status: Not subject to ADR/RID, IMDG, IATA transport restrictions
TSCA: Listed
REACH Status: Registered or pre-registered in applicable jurisdictions
SARA 302/304/311/312/313: Not listed as a hazardous substance under SARA regulations
California Prop 65: Substance not listed
WHMIS Classification: Not controlled
EU Classification: Not classified as hazardous under EC Regulation 1272/2008 (CLP)
Other Applicable Regulations: Pyridoxine hydrochloride use in foods, feeds, and pharmaceuticals subject to specific national and regional regulations
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
