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West Ujimqin Banner, Xilingol League, Inner Mongolia, China
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Product Name: Protease enzyme
Chemical Family: Enzyme preparation
Synonyms: Endopeptidase, Proteinase
Manufacturer: Enzyme Solutions Inc.
Contact Number: (888) 555-1234
Uses: Industrial and laboratory processes, food processing, textiles, detergents
Emergency Phone: (888) 555-4321
GHS Classification: Sensitizer, Respiratory Category 1; Sensitizer, Skin Category 1; Eye Irritation Category 2
Signal Word: Danger
Hazard Statements: May cause allergy or asthma symptoms, may cause allergic skin reaction, causes serious eye irritation, may cause respiratory irritation
Pictograms: Health hazard, exclamation mark
Precautionary Statements: Avoid breathing dust, use only outdoors or in well-ventilated areas, wear protective gloves, clothing, and eye protection
Potential Health Effects: Inhalation can trigger asthma or respiratory symptoms in sensitive individuals, skin contact can cause allergic responses, eye contact can irritate and redden eyes
Component: Protease enzyme
Chemical Formula: Not applicable (protein mixture)
Concentration Range: 1–99% (varies by formulation)
CAS Number: 9014-01-1
Impurities: Water, sodium chloride, stabilizing agents (if present)—do not contribute to hazard classification
Inhalation: Move person to fresh air immediately, keep comfortable for breathing, seek medical attention if symptoms continue
Skin Contact: Remove contaminated clothing, wash skin thoroughly with plenty of soap and water, consult physician for persistent irritation or allergy symptoms
Eye Contact: Rinse eyes carefully with water for at least 15 minutes, remove contact lenses if present and easy, seek professional care if irritation remains
Ingestion: Rinse mouth, offer water in small sips, do not induce vomiting, call poison center or physician for guidance
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Media: High-pressure water jet
Specific Hazards: Product may generate hazardous fumes such as oxides of carbon and nitrogen if burned at high temperature
Firefighting Instructions: Use self-contained breathing apparatus and full protective gear, avoid inhaling smoke or combustion byproducts, keep containers cool with water spray
Explosion Risk: Dust may form explosive mixtures with air in confined or poorly ventilated spaces
Personal Precautions: Evacuate unnecessary personnel, wear suitable respiratory protection, gloves, goggles, and coveralls
Environmental Precautions: Prevent spills from entering drains, surface water, or soil
Cleanup Methods: Ventilate area, use non-dusting techniques to sweep up spilled product, place waste in labeled, sealed containers for proper disposal, wash contaminated surfaces with water and mild detergent
Handling Released Material: Avoid creating dust, use vacuum or wet methods, do not use compressed air for cleanup
Handling: Handle in well-ventilated areas, minimize dust generation and accumulation, avoid contact with skin and eyes, do not breathe dust, wash hands after use
Storage: Keep containers tightly closed in dry, cool, ventilated space, segregate from incompatible substances like oxidizers and acids, store only in original containers
Incompatibilities: Strong oxidizing agents, strong acids, bases, extreme temperature exposures
Special Precautions: Label containers clearly, store away from food and animal feed, prevent unauthorized access
Occupational Exposure Limits: Enzyme dust—recommended TLV 0.00006 mg/m³ (as determined for some industrial enzymes)
Engineering Controls: Local exhaust ventilation at dust sources, general room ventilation, dust collection systems
Personal Protective Equipment: Respiratory protection such as NIOSH-approved particulate respirator, impermeable gloves (nitrile, latex), lab coat or disposable coveralls, safety glasses or face shield
Hygiene Measures: Wash after handling, do not eat, drink, or smoke during use, change contaminated clothing promptly and launder before reuse, provide eyewash facilities and safety shower
Appearance: White to off-white powder or granules
Odor: Slight, characteristic
Odor Threshold: Not established
pH (solution): 6.0 to 9.0 (for 1% aqueous solution)
Melting Point/Freezing Point: Decomposes before melting
Boiling Point: Not applicable
Flash Point: Not available
Evaporation Rate: Not applicable
Flammability: Not highly flammable, dust may be combustible
Vapor Pressure: Not relevant
Solubility: Soluble in water
Relative Density: 0.3–0.6 g/cm³
Partition Coefficient (n-octanol/water): Not established
Decomposition Temperature: Above 60°C with loss of enzymatic activity
Viscosity: Not applicable
Chemical Stability: Stable at room temperature under recommended conditions
Reactivity: No hazardous reactions under normal conditions of storage and use
Conditions to Avoid: Excessive heat, humidity, generation of dust, direct sunlight
Incompatible Materials: Strong oxidizing agents, acids, alkalis
Hazardous Decomposition Products: Combustion may release carbon oxides, nitrogen oxides, and ammonia
Polymerization: Will not occur
Acute Toxicity: Oral LD50 (rats): > 2000 mg/kg body weight
Inhalation: Can trigger allergy or asthma-like symptoms in sensitive individuals
Skin Contact: May cause sensitization, itching, or rash
Eye Contact: Causes irritation, redness, tearing
Chronic Effects: Prolonged inhalation or exposure increases risk of occupational asthma
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA
Mutagenicity: No evidence in standard tests
Reproductive Toxicity: Not known to cause reproductive harm
Ecotoxicity: Product biodegrades rapidly in the environment; low toxicity to aquatic organisms
Mobility in Soil: Protein binds to soil particles, unlikely to leach significantly
Persistence and Degradability: Readily biodegradable by microbial action
Bioaccumulative Potential: Low, due to protein degradation by environmental microorganisms
Other Harmful Effects: Large spills may create localized oxygen demand in water bodies
Waste Treatment Methods: Collect contaminated material, place in sealed, labeled containers, send to licensed waste disposal facility
Disposal of Product: Follow all local and national regulations for enzyme waste, avoid uncontrolled release to drains or environment
Container Disposal: Rinse containers, destroy labels, recycle or dispose of in accordance with regulations
UN Number: Not classified as hazardous for transport
Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not regulated
Marine Pollutant: No
Transport Precautions: Keep containers closed and secure, protect from moisture, handle with care to prevent damage and release of dust
Labeling According to GHS: Sensitizing, respiratory and skin hazard statements
National Inventory Status: Listed in TSCA, EINECS, AICS, DSL, ENCS, and other major chemical inventories
OSHA Regulations: Classified as hazardous by OSHA Hazard Communication Standard
SARA Title III: Not listed in SARA 302/304/313 categories
EPA Regulations: Complies with clean air and water regulations for industrial use
Other Regulations: Meets requirements for use in food and industrial applications under relevant national and international guidelines
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
