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Product Name: Polysorbate 60
Chemical Name: Sorbitan, mono-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivatives
Common Trade Names: Tween 60, Alkest TW 60, E435
CAS Number: 9005-67-8
Recommended Use: Emulsifier in personal care, food, pharmaceuticals, industrial formulations
Manufacturer/Supplier: Contact details provided on request, many global chemical suppliers distribute
Emergency Contact: Local poison control center or emergency services
GHS Classification: Not classified as hazardous under GHS
Physical Hazards: Not flammable, dust at high concentrations can become a hazard through inhalation
Health Hazards: May cause mild eye and skin irritation, ingestion in large amounts may lead to stomach disturbance
Environmental Hazards: Spillages may create slip risk; aquatic toxicity considered low, but avoid release to surface water
Signal Word: Not applicable
Hazard Statements: No significant hazards identified
Precautionary Statements: Wear suitable protective clothing, avoid excessive inhalation of dust
Main Components: Polysorbate 60 (≥ 98%)
Chemical Formula: C64H126O26
Impurities: Water (<1%), fatty acid esters, minor by-products from production
Stabilizing Additives: None typically added
Molecular Weight: Approx. 1310 g/mol
Inhalation: Move person to fresh air, seek medical advice if symptoms such as coughing or respiratory irritation persist
Skin Contact: Remove contaminated clothing, rinse affected skin with soap and water, get medical attention if irritation continues
Eye Contact: Rinse thoroughly with water for at least 15 minutes, keep eyelids open, consult a physician if discomfort persists
Ingestion: Rinse mouth with water, do not induce vomiting, drink water to dilute, seek medical attention if unwell
General Advice: Provide medical personnel with this MSDS if symptoms develop
Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide, water spray (do not use water jet directly on burning product)
Specific Fire Hazards: Combustion may produce carbon monoxide, carbon dioxide, various organic compounds
Protective Equipment: Firefighters should use self-contained breathing apparatus and protective clothing
Special Procedures: Cool exposed containers with water spray, contain contaminated water for disposal
Personal Precautions: Use gloves, eye protection, dust mask if powder becomes airborne
Environmental Precautions: Prevent from entering drains, sewers, water sources
Containment Methods: Stop leak if safe, block runoff using sand or earth, clear area to avoid slips
Cleanup Methods: Collect in suitable containers for recycling or disposal, wash spill area with water and detergent, ventilate site thoroughly
Safe Handling: Avoid inhaling dust, spilling on floors, splashing in eyes, wear suitable personal protective equipment during bulk transfer or mixing
Storage Conditions: Store in tightly sealed containers, cool and dry environment, away from incompatible materials like strong oxidizing agents
Incompatibilities: Strong oxidizers, acids or bases cause product degradation or hazardous reactions
Specific Practices: Keep away from food, feedstuffs, minimize all unnecessary exposure, maintain good hygiene around storage area
Exposure Limits: No established exposure limits
Engineering Controls: Ensure adequate ventilation, use local exhaust during bulk handling, install safety showers and eyewash stations
Personal Protective Equipment: Safety glasses, gloves (nitrile or PVC), dust mask, long sleeves
Hygiene Measures: Wash hands before eating, drinking, smoking, or leaving work area, launder clothing regularly
Appearance: Creamy white to pale yellow semi-solid or pasty mass
Odor: Very mild, fatty or oily odor
pH (1% solution): 5.0 – 7.0
Boiling Point: Decomposes before boiling
Melting Point: 23–26°C (73–79°F)
Flash Point: >150°C (302°F) (closed cup method)
Solubility: Dispersible in water, soluble in ethanol and most organic solvents
Vapor Pressure: Negligible at room temperature
Relative Density: 1.08–1.12 g/cm³ (20°C)
Partition coefficient (n-octanol/water): LogPow approx. 9.4
Chemical Stability: Stable under normal storage and handling conditions
Hazardous Decomposition: Produces irritating fumes, carbon oxides if burned
Incompatible Materials: Strong oxidizing agents, strong acids or bases
Hazardous Reactions: None expected in normal use
Polymerization: Not known to occur
Acute Toxicity: Low acute toxicity by oral, dermal, inhalation routes (LD50 >5000 mg/kg oral, rat)
Chronic Toxicity: No evidence of carcinogenicity, mutagenicity; chronic exposure may lead to mild skin or eye irritation in sensitive people
Sensitization: Rarely associated with allergic reaction
Potential Health Effects: Eye: mild irritant; Skin: mild irritant; Inhalation: irritation possible if dust is generated; Ingestion: large amounts can cause gastrointestinal upset
Target Organs: No organs specifically affected under normal industrial or consumer exposure
Aquatic Toxicity: Low toxicity to aquatic life (LC50 >100 mg/L, fish, 96h)
Persistence and Degradability: Readily biodegradable; does not persist in the environment
Bioaccumulative Potential: Bioaccumulation unlikely due to molecule size and water solubility
Soil Mobility: Moderate mobility, binds to soil in larger spills
Other adverse effects: No significant negative impact on biodiversity or microbial balance at recommended use levels
Disposal Methods: Dispose according to local, state, national regulations for non-hazardous organic chemicals
Incineration: Suitable at approved facility
Landfill: Acceptable for small quantities in accordance with local waste authority approvals
Container Disposal: Rinse empty containers before recycling or reuse, comply with official requirements
Precautions: Avoid discharge into natural waterways or sewage
UN Number: Not regulated as hazardous for transport
Transport Classification: Non dangerous good (ADR/RID, IMDG, IATA)
Packaging Requirements: Use sealed, chemical-resistant containers, avoid leaks
Special Precautions: Protect from excessive heat, moisture, keep containers upright and labelled during transit
US TSCA: Listed on Toxic Substances Control Act inventory
EU REACH: Registered, compliant with current chemical management laws
Canada DSL/NDSL: Listed
Australia AICS: Listed
Japan ENCS: Listed
Food Additive Regulation: Approved as emulsifier (E435) in food across EU, US, Canada, JP with specified maximum levels
Workplace Rules: Not classified as hazardous, minimal mandatory labelling under global labelling standards
Waste Codes: Follow local non-hazardous waste regulation for coding and management
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
