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Product Name: Plant Sterols
Chemical Family: Phytosterols
Common Names: Beta-sitosterol, Campesterol, Stigmasterol
CAS Numbers: 83-46-5 (beta-sitosterol), 474-62-4 (campesterol), 83-48-7 (stigmasterol)
Recommended Use: Ingredient in functional foods, dietary supplements, pharmaceuticals
Supplier Details: Manufacturer’s address, emergency contact number, business phone, email for technical inquiries
GHS Classification: Not classified as hazardous per OSHA Hazard Communication Standard
Signal Word: None
Hazard Statements: Dust may cause slight eye or respiratory irritation.
Precautionary Statements: Use with adequate ventilation. Avoid creating dust clouds.
Potential Health Effects: Prolonged inhalation may cause mild respiratory discomfort. May cause minimal and reversible eye irritation. Not considered a skin sensitizer.
Environmental Hazards: Not considered hazardous to aquatic or terrestrial environments at typical concentrations
Beta-sitosterol: 60–80%
Campesterol: 10–30%
Stigmasterol: 2–20%
Other Plant Sterols: Trace components include brassicasterol and avenasterol
Impurities: Small amounts of plant-derived non-sterol compounds (esters, waxes, fatty alcohols)
Chemical Formula: Mixture of polycyclic alcohols (C29H50O, C28H48O, C29H48O)
Inhalation: Move affected individual to fresh air. Seek medical attention if symptoms persist.
Skin Contact: Wash with mild soap and water. Remove contaminated clothing and launder before reuse. Seek medical help for irritation that does not subside.
Eye Contact: Flush eyes with plenty of water for several minutes. Remove contact lenses if present and easy to do. Get medical attention if irritation continues.
Ingestion: Rinse mouth with water. Drink water to dilute. If large amounts are ingested or if discomfort develops, seek immediate medical advice.
Most Important Symptoms / Effects: Mild, short-term irritation of eyes, skin or respiratory tract; no expected delayed or chronic symptoms from typical exposure
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam for small fires. Avoid streams of water that may spread dust.
Specific Hazards: Dust may form explosive mixtures with air. Burning produces carbon oxides.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear.
Special Procedures: Cool exposed containers with water spray. Avoid inhaling combustion fumes. Remove personnel from area if safe to do so.
Personal Precautions: Avoid dust inhalation and eye contact. Wear respiratory mask, safety glasses, and gloves.
Environmental Precautions: Prevent product from entering drains, waterways or soil in large quantities.
Containment and Cleanup: Sweep up or vacuum spilled material without creating dust clouds. Place in suitable containers for reuse or disposal. Ventilate area. Wash spill site after material pickup is complete.
Handling: Handle in a well-ventilated area. Minimize dust generation and accumulation. Use non-sparking tools and equipment. Ground material-handling systems.
Storage: Store in tightly closed containers, in a cool, dry, well-ventilated place away from incompatible materials such as oxidizers. Protect from direct sunlight, moisture, and strong acids/bases.
Exposure Limits: No OSHA PEL or ACGIH TLV set. Nuisance dust limits may apply (TLV-TWA 10 mg/m³ for inhalable particles).
Engineering Controls: Provide local exhaust, general ventilation, or both to control airborne dust.
Personal Protective Equipment: Wear safety goggles, gloves, and dust mask or respirator if dust levels exceed guidelines. Use protective clothing as needed.
Hygiene Measures: Wash hands and exposed skin after handling. Do not eat, drink, or smoke in processing areas.
Appearance: White to off-white powder or flakes
Odor: Mild, characteristic plant-like
pH: Not applicable for solid
Melting Point: 135-145°C (beta-sitosterol); varying for mixed sterols
Boiling Point: Decomposes before boiling
Flash Point: Not established; combustible at elevated temperatures
Solubility: Insoluble in water; soluble in alcohol, chloroform, and oils
Density: 0.85–1.0 g/cm³
Partition Coefficient: High log P (octanol/water), favoring lipid solubility
Vapor Pressure: Negligible at room temperature
Autoignition Temperature: >400°C
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Not reactive with common substances
Conditions to Avoid: Heat, sources of ignition, open flames, strong oxidizers
Incompatible Materials: Strong acids, bases, and oxidizing agents
Hazardous Decomposition: Thermal decomposition produces carbon monoxide, carbon dioxide, and possibly other organic vapors
Acute Toxicity: Low acute oral and dermal toxicity; high LD50 in animal studies (>5000 mg/kg for rats)
Chronic Effects: No evidence of chronic toxicity or carcinogenicity at normal exposure
Skin and Eye Contact: No significant irritation expected from occasional direct contact
Sensitization: Not considered a skin sensitizer
Inhalation: Large amounts of dust can produce mild, transient discomfort
Mutagenicity: Negative in standard mutagenicity tests
Other Effects: Considered safe for dietary consumption in levels seen in food supplements
Ecotoxicity: Low environmental hazard due to poor water solubility and rapid biodegradation
Persistence and Degradability: Readily biodegradable in soil and aquatic environments
Bioaccumulation Potential: Low potential due to metabolic breakdown in organisms
Mobility in Soil: Minimal due to low water solubility
Other Environmental Effects: Does not cause algal blooms or disrupt aquatic food webs at expected concentrations
Safe Disposal Methods: Dispose as non-hazardous solid waste according to local, state, and federal regulations.
Unused Product: Landfill or incineration is suitable. Consider resale or recycling for uncontaminated material.
Contaminated Packaging: Rinse containers and recycle where possible. Dispose of according to regulations.
Precautions: Avoid dust generation and environmental release of powder during disposal.
UN Number: Not regulated
Proper Shipping Name: Not regulated – Plant Sterols
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Protect from excessive heat, moisture, and impact damage during transit. Use standard dry goods shipping practices.
Regulations: No special transport requirements under ADR, IMDG, IATA, USDOT, or Canadian TDG rules
OSHA: Not classified as hazardous under OSHA regulations
FDA: Authorized for use as food additive and dietary supplement; GRAS status for some preparations
REACH Registration: Exempt or pre-registered as derived from natural plant materials
TSCA Inventory: Registered
WHMIS/GHS: Not controlled, no special labeling required
Labeling: No signal word or hazard pictograms mandated by GHS
Other Regulations: Subject to standards for nutritional products and dietary supplements. Product registration may be required in some jurisdictions; check relevant local and national laws for compliance
