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Product Name: Phytase enzyme concentrate
Chemical Family: Enzyme preparation
Manufacturer and Address: Enzyme Solutions Inc., 245 Science Park Drive, Waltham, MA 02451, USA
Emergency Contact Number: +1-800-555-1212
Trade Name/Synonyms: Phytase, Natuphos, Finase
Recommended Use: Animal feed additive to increase nutrient availability
CAS Number: 37288-11-2
UN Number: Not regulated
Date Prepared: 2024-06-15
GHS Classification: Sensitizing agent (respiratory, skin)
Label Elements: Warning symbol for sensitizer
Hazard Statements: May cause respiratory sensitization, may cause skin sensitization in sensitive individuals, dust may irritate mucous membranes and eyes
Precautionary Statements: Avoid inhaling dust, avoid skin and eye contact, wear suitable personal protection
Other Hazards: No acute toxicity; can trigger allergies in people with enzyme sensitivity
Active Ingredient: Phytase enzyme protein, 10–40%
Inactive Ingredients: Sodium sulfate (carrier), corn starch, wheat flour, potassium chloride
Potential Allergens: Wheat derivatives
Impurities: Trace fermentation by-products
Inhalation: Move affected person to fresh air, seek medical attention for symptoms such as coughing or shortness of breath
Skin Contact: Wash affected area immediately with soap and water, remove contaminated clothing
Eye Contact: Rinse eyes with water for at least 15 minutes, keep eyelids open, remove contact lenses, seek medical help if irritation persists
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical help if large quantities are swallowed or symptoms develop
Most Important Symptoms: Allergic reactions, skin rash, respiratory distress
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Unsuitable Media: Direct water jet on powder
Special Firefighting Procedures: Wear self-contained breathing apparatus and full personal protection; hazardous decomposition products such as carbon oxides and nitrogen oxides can release
Unusual Fire Hazards: Product can become airborne as a dust in a fire, increasing the risk of inhalation
Combustion Products: Carbon oxides (CO, CO2), nitrogen oxides
Personal Precautions: Ventilate area, avoid breathing dust, wear gloves, safety goggles, and dust mask
Environmental Precautions: Prevent large product release from entering drains or water supplies to reduce accidental exposure in aquatic systems
Cleanup Methods: Sweep or vacuum material without raising dust, place in sealed containers for disposal, wash area with water after cleanup
Emergency Procedures: Remove non-essential personnel, use respiratory protection for large spills
Handling: Use local exhaust ventilation to limit airborne dust levels, avoid skin and eye contact, do not eat, drink, or smoke while using chloride-based mixes, keep container tightly closed
Storage Conditions: Store in a cool, dry, ventilated place, away from direct sunlight and oxidizing agents, maintain in original packaging
Incompatible Materials: Strong acids, oxidizers
Recommended Storage Temperature: 4–25°C
Storage Duration: Keep product dry and use within shelf life for full enzyme activity
Occupational Exposure Limits: No OSHA PEL established specifically for phytase; ACGIH TLV for proteinaceous enzymes (0.00006 mg/m3 inhalable fraction as a guideline)
Engineering Controls: Local exhaust ventilation, enclosed operations to minimize dust
Respiratory Protection: NIOSH-approved dust mask or respirator in areas with dust
Eye Protection: Safety goggles
Hand Protection: Chemical-resistant gloves (nitrile or latex)
Other Protective Equipment: Lab coat or coveralls, closed-toe shoes, eyewash station nearby
Appearance: Fine off-white to pale brown free-flowing powder
Odor: Mild, characteristic
pH (1% solution): 4.5–6.0
Melting Point/Range: Not applicable (decomposes before melting)
Solubility in Water: Dispersible, partially soluble
Bulk Density: 0.55–0.75 g/cm3
Vapor Pressure: Not applicable
Flash Point: Not flammable under normal conditions
Partition Coefficient: Not applicable
Decomposition Temperature: >50°C (loss of enzyme activity)
Chemical Stability: Stable under normal ambient conditions, less stable in humid or hot environments
Hazardous Reactions: None expected under normal storage; strong acids or oxidizers may denature the product
Hazardous Decomposition Products: Thermal decomposition yields carbon oxides, nitrogen oxides
Conditions to Avoid: High heat, excess moisture, direct sunlight, incompatible chemicals
Incompatibilities: Strong acids, alkalis, oxidizers
Acute Toxicity: Low oral and dermal toxicity expected in animal studies
Chronic Effects: Frequent inhalation sensitizes individuals, risk of asthma or allergic reactions grows with repeated handling
Carcinogenicity: Not listed by NTP, IARC, or OSHA
Mutagenicity: No mutations reported in standard Ames tests
Skin/Eye Irritation: Possible mild irritant; skin rashes and eye irritation can occur if exposed
Target Organs: Respiratory tract, skin, eyes
Symptoms of Exposure: Sneezing, coughing, shortness of breath, itching, redness, rash
Sensitization: Confirmed respiratory and skin sensitizer in some individuals
Ecotoxicity: Product breaks down rapidly in soil and water, degradable by microbes, expected low toxicity to aquatic life
Persistence and Degradability: Readily biodegradable
Bioaccumulative Potential: Product is a protein, not expected to accumulate
Mobility in Soil: Moves with water but is quickly broken down
Other Adverse Effects: Excess release may cause localized nutrient enrichment, encourage microbial activity in water
Waste Disposal Methods: Incinerate under controlled conditions or landfill according to local, state, and federal regulations
Contaminated Packaging: Rinse thoroughly before reuse or disposal
Special Instructions: Avoid release into environment, do not flush into surface water, handle dust with care to avoid airborne allergen exposure
Unused Product: Dispose as non-hazardous industrial waste unless mixed with hazardous materials
UN Number: Not classified
Proper Shipping Name: Phytase enzyme preparation
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Special Precautions: Protect from moisture during transport, use sealed containers
OSHA: Considered non-hazardous except for risk of enzyme sensitization
TSCA: All ingredients listed or exempt
EU REACH: Exempt as a product derived from natural organisms
US FDA/GRAS: Generally Recognized As Safe for intended animal feed use
Labeling Requirements: Sensitizer warning; ingredients and safety instructions; batch and expiry information
SARA Title III Sections 311/312: Not classified as a hazardous chemical
Canadian DSL/NDSL: Listed
Inventory Listings: Active on AICS, NZIoC, ENCS, KECI, PICCS
Additional Information: Follow safety, health, and environmental regulations; employees should receive training in enzyme safety
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
