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Material Safety Data Sheet (MSDS) for Phospholipid

Identification

Product Name: Phospholipid
Chemical Name: Phospholipid (complex lipid, naturally occurring)
Synonyms: Lecithin, 1,2-diacyl-sn-glycero-3-phosphocholine
CAS Number: 8002-43-5
Recommended Use: Food additive, pharmaceutical emulsifier, cosmetic ingredient
Manufacturer: Supplier information available upon request
Emergency Contact: Refer to local Poison Control Center or emergency services

Hazard Identification

Classification: Not classified as hazardous under GHS
Hazard Statements: May cause mild skin or eye irritation in sensitive individuals
Precautionary Statements: Avoid contact with eyes and prolonged skin exposure; maintain good industrial hygiene
Routes of Exposure: Inhalation (dust), skin and eye contact, ingestion
Symptoms: Mild redness, irritation, or discomfort may occur
Label Elements: None required under GHS for pure phospholipid

Composition / Information on Ingredients

Chemical Ingredients: Phosphatidylcholine (>60%), minor amounts of phosphatidylethanolamine, phosphatidylinositol, and phosphatidylserine
Purity: Ranges from 60% to 98% (varies with manufacturing process)
Impurities: Residual solvents, trace triglycerides, fatty acids
Additives: None in pure form
Molecular Formula: C42H82NO8P (typical for phosphatidylcholine type)

First Aid Measures

Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses when easy; get medical attention for persistent irritation
Skin Contact: Wash gently with soap and water; remove contaminated clothing; seek attention if symptoms persist
Inhalation: Move to fresh air, support breathing if exposed to dust; consult a physician for respiratory symptoms
Ingestion: Rinse mouth; drink water to dilute; do not induce vomiting; seek medical advice for discomfort
Notes for Doctor: Treat symptomatically based on patient’s condition

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray (fog), dry chemical, foam, or carbon dioxide
Unsuitable Extinguishing Media: High-pressure water jets may spread material
Hazards from Fire: Dense smoke, fumes of phosphorus oxides, carbon oxides
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear
Special Procedures: Cool surrounding areas with water spray; prevent runoff from entering waterways

Accidental Release Measures

Personal Precautions: Wear gloves and safety glasses to avoid contact; use dust mask if powder is present
Environmental Precautions: Do not allow large amounts to enter drains or surface water
Spill Clean-up Methods: Sweep up solids carefully, avoid creating dust, transfer to containers for disposal; wash area with soap and water
Disposal: Follow regulations for disposal; contain and collect spills for proper treatment

Handling and Storage

Handling: Minimize dust generation, avoid direct contact, ensure adequate ventilation; wash hands after handling
Storage: Store tightly sealed in cool, dry locations; keep away from direct sun, strong oxidizers, intense moisture
Incompatible Materials: Avoid contact with strong acids, alkalis, and oxidizing agents
Storage Life: Usually stable for 1-2 years under recommended conditions

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation when handling powders; maintain workplace cleanliness
Personal Protection: Safety glasses or goggles, chemical-resistant gloves, lab coat
Respiratory Protection: NIOSH-approved dust mask in case of airborne particles
Exposure Limits: No specific TLV or OEL for phospholipids
Hygiene Measures: Wash thoroughly after use, do not eat or drink during handling

Physical and Chemical Properties

Appearance: Pale yellow to brown powder or viscous liquid (depending on grade)
Odor: Mild, characteristic fatty odor
pH: Neutral to slightly acidic (<7.0, 2% in water)
Melting Point: 60-70°C (powder type)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Insoluble in water; soluble in ethanol, chloroform, and ether
Density: 1.03-1.06 g/cm³
Flash Point: Estimated >150°C (Closed cup)
Auto-ignition Temperature: Above 300°C

Stability and Reactivity

Chemical Stability: Stable under normal storage, sensitive to prolonged exposure to air, light, and moisture
Conditions to Avoid: High humidity, strong heat, contact with reactive chemicals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, phosphorus oxides, acrolein with overheating
Polymerization: Not known to occur
Incompatibility: Strong acids, oxidizing agents, alkali substances

Toxicological Information

Acute Toxicity: Very low oral and dermal toxicity reported for soy lecithin type; typical LD50 (rat, oral): >5000 mg/kg
Skin Corrosion/Irritation: Rare mild irritation in sensitive individuals
Eye Damage/Irritation: Slight irritation possible
Respiratory Sensitization: No reports of sensitization
Carcinogenicity: No classification by IARC, NTP, or OSHA
Repeated Dose Toxicity: Studies show no observed significant adverse effects with regular exposure at dietary levels
Other Effects: No mutagenic or reproductive toxicity data suggests significant risk

Ecological Information

Environmental Effects: Biodegradable, low bioaccumulation risk
Aquatic Toxicity: Not considered toxic at concentrations likely in spills
Persistence: Rapidly breaks down in soil and water via microbial activity
Mobility in Soil: Low due to high molecular weight, adherence to particles
Other Adverse Effects: No significant long-term environmental impact anticipated

Disposal Considerations

Waste Disposal Methods: Dispose as non-hazardous industrial waste in accordance with local, state, and national regulations
Containers: Triple rinse containers, then place in recycling or approved landfill
Special Precautions: Prevent material from entering waterways or sewers in significant quantities
Waste Codes: Not assigned hazardous waste code under US RCRA regulations

Transport Information

UN Number: Not assigned
Transport Hazard Class: Not regulated for transportation
Packing Group: Not applicable
Marine Pollutant: No
Special Transport Precautions: Protect from moisture and excessive heat during transit

Regulatory Information

OSHA Status: Not specifically regulated as a hazardous substance
TSCA: Listed
EU REACH: Exempt as a naturally occurring lipid used in food, pharma, and cosmetics
FDA: Approved as GRAS (Generally Recognized As Safe) for food use
Other National Regulations: Check regional regulatory requirements for product use and disposal
Labeling Requirements: None required for bulk product under typical regulatory frameworks