Contact Us
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
© 2025 Alchemist Worldwide Ltd, All Right Reserved
Product Name: Phospholipase A2
Synonyms: PLA2, Phosphatide 2-acylhydrolase, Group I/II PLA2
CAS Number: 9001-84-7
Manufacturer: [Name and address of a registered supplier]
Recommended Uses: Laboratory reagent, pharmaceutical research, biotechnology applications
Contact Information: [Contact phone, emergency telephone, email]
GHS Classification: Acute toxicity (oral, dermal, inhalation - Category 3), Respiratory sensitization (Category 1), Skin sensitization (Category 1), Eye damage/irritation (Category 2A)
Signal Word: Danger
Hazard Statements: Toxic if swallowed, in contact with skin or inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause allergic skin reactions. Causes serious eye irritation.
Precautionary Statements: Wear protective gloves, clothing, eye/face protection, avoid breathing dust or spray, wash hands thoroughly after handling, use only outdoors or in well-ventilated areas.
Label Elements: Skull and crossbones, exclamation mark
Chemical Name: Phospholipase A2
CAS Number: 9001-84-7
Concentration: ≥95% by weight
Impurities/Additives: May contain trace proteins, buffer salts and stabilizers from biological source extraction.
Molecular Formula: Variable, proteinaceous compound (typical MW ~13,000–20,000 Da)
Source: Isolated from animal tissue (snake venom), bacterial cultures, or recombinant expression systems.
Inhalation: Move person to fresh air. Keep at rest in comfortable position. Get medical attention if symptoms appear or persist.
Skin Contact: Wash affected area with soap and water immediately. Remove contaminated clothing and shoes. Medical care if irritation occurs.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical attention if irritation persists.
Ingestion: Rinse mouth with water. Never give anything by mouth to an unconscious person. Get immediate medical help.
Most important symptoms/effects: Respiratory distress, allergic reactions, skin and eye irritation.
Suitable Extinguishing Media: Dry chemical, CO2, foam, water spray (for larger fires)
Specific Hazards: May liberate toxic fumes (carbon oxides, nitrogen oxides, sulfur compounds) on burning.
Protective Equipment: Self-contained breathing apparatus, full protective gear.
Special Procedures: Evacuate area, prevent water from entering drains, avoid inhalation of combustion products.
Personal Precautions: Avoid breathing dust or vapors. Wear gloves, goggles, lab coat, and dust mask. Provide adequate ventilation.
Environmental Precautions: Prevent further leakage or spillage if safe to do so. Avoid runoff to waterways or sewers.
Clean-up Methods: Scoop up and place in suitable container for disposal. Use damp cloths to clean residue. Wash spill area with detergent and water. Dispose of contaminated materials as hazardous waste.
Emergency Procedures: Inform appropriate authorities and follow institutional protocols for spills involving biohazardous or allergenic enzymes.
Handling: Keep containers tightly closed. Work in designated areas with adequate ventilation. Avoid dust formation and exposure to skin, eyes, and clothing. Do not ingest or inhale.
Storage: Store at 2–8°C. Protect from light, moisture, and incompatible materials (strong acids, bases, oxidizers). Use only original containers with properly fitted caps or lids. Restrict access to trained personnel.
Occupational Exposure Limits: No values established for PLA2; minimize exposure using best practices.
Engineering Controls: Use fume hood or local exhaust ventilation. Handle in controlled-access laboratory.
Personal Protective Equipment: Chemical-resistant gloves (nitrile), lab coat, safety glasses with side shields, particulate respirator or N95 mask if risk of dust/aerosol present. Remove contaminated clothing promptly. Emergency eyewash and shower accessible.
Hygiene Measures: Wash hands after handling. Avoid eating, drinking, or smoking in laboratory.
Appearance: White to off-white lyophilized powder or crystalline solid
Odor: Odorless or slight proteinaceous smell
pH: Neutral (6–8) in solution
Melting Point/Range: Not applicable (decomposes on heating)
Boiling Point/Range: Not applicable (protein decomposition)
Flash Point: Not flammable
Solubility: Water soluble, may require buffer (e.g., PBS, Tris)
Vapor Pressure: Not relevant (non-volatile)
Relative Density: Not determined
Partition Coefficient (n-octanol/water): Not determined
Decomposition Temperature: Above 50°C (protein denaturation)
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions. Sensitive to temperature, proteases, and pH extremes.
Reactivity: Reacts with strong oxidizers, strong acids/bases.
Conditions to Avoid: Heat, direct sunlight, freezing, humidity, strong oxidants.
Incompatible Materials: Acids, bases, strong oxidizing agents.
Hazardous Decomposition Products: Toxic fumes of nitrogen oxides, carbon monoxide/dioxide, sulfur oxides under fire conditions.
Routes of Exposure: Inhalation, ingestion, dermal, ocular
Acute Toxicity: Highly toxic by ingestion, inhalation and skin contact. May result in respiratory distress, vomiting, pain, or systemic toxicity.
Skin Corrosion/Irritation: Causes skin irritation and allergic skin reactions.
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation.
Respiratory Sensitization: Allergic asthma, difficulty breathing, cough.
Skin Sensitization: Can trigger allergic dermatitis.
Carcinogenicity: No data available for carcinogenic potential.
Mutagenicity/Reproductive Toxicity: Not classified as mutagenic or reproductive toxin by current sources.
Chronic Effects: Allergic reactions, respiratory sensitization.
LD50 Values: Range from 5–20 mg/kg (animal models, intravenous)
Ecotoxicity: Protein-based compound, possible toxicity to aquatic life based on enzymatic activity and source.
Persistence/Degradability: Readily biodegradable, rapid breakdown by natural microorganisms.
Bioaccumulative Potential: Low, due to peptide nature.
Mobility in Soil: Moderate mobility expected for dissolved enzyme, adsorbs to organic matter.
Other Effects: Avoid release to environment. Collect spillage appropriately.
Waste Treatment Methods: Dispose of as hazardous laboratory waste.
Product Disposal: Incinerate in licensed chemical incinerator or send with licensed hazardous waste contractor.
Container Disposal: Triple rinse, remove labels, dispose as chemical waste.
Special Precautions: Do not discharge into drains, surface water, or soil.
Regulatory Requirements: Follow all local, regional, and national laws on enzyme waste.
UN Number: Not assigned (consult latest regulations)
UN Proper Shipping Name: Proteinaceous, toxic solid, n.o.s. (Phospholipase A2)
Transport Hazard Class: 6.1 (Toxic Substances)
Packing Group: III
Environmental Hazards: Not classified as marine pollutant.
Special Transport Precautions: Keep in secondary containment, emergency spill kit available. Protect from heat, rough handling.
OSHA Status: Hazardous, meets criteria for hazardous chemicals
TSCA Inventory: Not listed (biologicals of this type generally exempt)
DSL/NDSL Status (Canada): Not listed
EU Regulations: Classified under Regulation (EC) No 1272/2008; toxic enzyme
REACH Registration: Exempt as naturally occurring protein, if non-recombinant
SARA Title III: Hazard: Immediate health
WHMIS Classification: D1A (very toxic material causing immediate and serious toxic effects), D2B (toxic material causing other effects)
Labeling Requirements: Follow all U.S. or regional regulatory labeling, including GHS pictograms and warnings.
Other Information: For research use only, not for diagnostic or therapeutic use in humans or animals unless specifically authorized.
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
