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Material Safety Data Sheet: Phosphatidylserine

Identification

Product Name: Phosphatidylserine
Chemical Formula: C13H24NO10P
Synonyms: PS, 1,2-diacyl-sn-glycero-3-phospho-L-serine
Recommended Use: Dietary supplement, research
Manufacturer: Listed by brand or supplier
Emergency Contact: Provided by manufacturer or distributor

Hazard Identification

GHS Classification: Not considered hazardous by GHS criteria for this product
Label Elements: No signal word, pictogram, or hazard statement required
Hazard Statements: May cause mild irritation to eyes, skin, or respiratory tract in sensitive individuals
Precautionary Statements: Avoid dust formation, wash hands after handling, handle in well-ventilated area
Routes of Exposure: Inhalation, skin and eye contact
Potential Health Effects: Ingestion poses minimal risk; slight irritation possible on contact
Chronic exposure: No evidence of adverse chronic effects reported in humans

Composition / Information on Ingredients

Chemical Name: Phosphatidylserine
Chemical Formula: C13H24NO10P
CAS Number: 51446-62-9
Concentration: >98% pure
Impurities: Trace amounts of other phospholipids, solvent residues possible depending on manufacturer
Additives: None typically present

First Aid Measures

Inhalation: Move to fresh air. Seek medical attention if symptoms develop or persist.
Skin Contact: Wash affected area with soap and water. Remove contaminated clothing and seek medical help if irritation occurs.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. If irritation persists, seek medical attention.
Ingestion: Rinse mouth with water. Drink water. Do not induce vomiting unless instructed by medical personnel. Seek medical attention if symptoms develop.

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or foam.
Specific Hazards: Product may produce toxic fumes of carbon oxides, nitrogen oxides, and phosphorus oxides if burned.
Advice for Firefighters: Wear self-contained breathing apparatus and full protective gear. Avoid inhalation of combustion products. Remove containers from fire if safe to do so.
Explosion Data: None known for this material under normal handling.

Accidental Release Measures

Personal Precautions: Avoid dust generation. Ensure adequate ventilation. Wear suitable protective equipment.
Environmental Precautions: Prevent entry into drains, sewers, or waterways.
Cleanup Methods: Sweep or vacuum spill. Place in suitable, closed container for disposal. Avoid creating airborne dust.
Other Precautions: Observe established workplace hygiene practices during cleanup.

Handling and Storage

Safe Handling: Handle in accordance with good industrial hygiene and safety procedures. Avoid dust formation. Use in well-ventilated area. Avoid contact with skin, eyes, or clothing.
Safe Storage: Store in cool, dry place away from heat, flame, or direct sunlight. Keep container tightly closed and properly labeled. Avoid strong oxidizing agents.
Incompatible Materials: Strong acids, strong bases, strong oxidizing agents.
Specific Use: For research or supplement use only; not for diagnostic or therapeutic use unless directed.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits by OSHA, ACGIH, or NIOSH
Engineering Controls: Use local exhaust or general ventilation. Maintain air concentrations below nuisance dust threshold (typically 10 mg/m³ for total dust).
Personal Protection: Wear chemical splash goggles, lab coat, and suitable gloves (nitrile or latex). Use dust mask or respirator for dusty conditions or high exposures.
Hygiene Measures: Wash hands thoroughly after handling. Do not eat, drink, or smoke in areas where this substance is handled. Remove contaminated clothing before re-use.

Physical and Chemical Properties

Appearance: White to off-white powder
Odor: Mild, fatty odor
Odor Threshold: Not applicable or not determined
pH: Not determined in aqueous solution
Melting Point/Freezing Point: Around 81-83°C
Boiling Point/Range: Not applicable (decomposes)
Flash Point: Not applicable or not determined
Evaporation Rate: Not determined
Flammability: Not highly flammable, but may burn at high temperatures
Vapor Pressure: Negligible
Relative Density: Not determined
Solubility (Water): Insoluble; disperses in some organic solvents and lipids
Partition Coefficient (n-octanol/water): Not determined
Autoignition Temperature: Data not available
Decomposition Temperature: Data not available
Viscosity: Not applicable (solid)

Stability and Reactivity

Chemical Stability: Stable under normal conditions of storage and handling
Reactivity: Not reactive under standard use
Hazardous Reactions: None known under standard use
Conditions to Avoid: Exposure to strong heat, humidity, or incompatible chemicals
Incompatible Materials: Strong acids, bases, and oxidizing agents
Hazardous Decomposition Products: May generate carbon oxides, nitrogen oxides, phosphorus oxides on thermal decomposition

Toxicological Information

Acute Toxicity: No acute toxicity expected at levels of use in food or research
Skin Corrosion/Irritation: Unlikely to cause significant irritation, possible mild irritant
Eye Damage/Irritation: May cause mechanical irritation
Respiratory Sensitization: Not classified, but dust may cause transient irritation
Germ Cell Mutagenicity: Not expected to be mutagenic
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: Not expected to harm fertility or development based on available studies
Long-term Exposure: No significant adverse effects reported in available literature

Ecological Information

Ecotoxicity: Not expected to be hazardous to the environment at normal volumes
Persistence and Degradability: Expected to be biodegradable; phosphatidylserine breaks down naturally
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: Low; expected to adsorb to soil particles
Other Adverse Effects: No information suggests hazard to aquatic or terrestrial organisms in typical quantities used.

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations.
Product Disposal: Small quantities may be disposed of in landfill or incinerated, subject to local laws.
Packaging Disposal: Clean containers before recycling or disposal. Avoid release of powder into the environment.

Transport Information

UN Number: Not regulated
Shipping Name: Not classified as a hazardous material for shipping
Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Transport Precautions: Keep containers closed, dry, protected from physical damage during transit.

Regulatory Information

OSHA Status: Not regulated as hazardous by OSHA standards
TSCA Inventory: Listed
DSL/NDSL (Canada): Listed
EU REACH: Registered for intended uses
Other Regulations: Not subject to significant regulatory controls in most regions; observe standard chemical handling regulations
Labeling Requirements: Use as per food, supplement, or research labeling standards as applicable