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Material Safety Data Sheet: Panax Ginseng Extract

1. Identification

Product Name: Panax Ginseng Extract
Other Names: Asian Ginseng Extract, Korean Ginseng Extract
Recommended Use: Dietary supplement ingredient, herbal medicine component, cosmetic additive
Supplier Details: Standard supply chain details include manufacturer’s address, phone, emergency contact
Emergency Contact: Refer to local poison control centers or on-site safety officer
CAS Number: 90045-38-8

2. Hazard Identification

Main Hazards: Dust formation irritates respiratory tract; possible skin and eye irritation on contact
Environmental Hazard: Bulk spills may affect aquatic environments if not contained
Signal Word: None required under GHS for common extract forms
Precautionary Statements: Avoid inhaling powder, prevent direct skin or eye contact, control dust buildup
GHS Classification: Not classified as hazardous under most regulatory schemes, but treat with basic care

3. Composition / Information on Ingredients

Ingredient: Extract from roots of Panax ginseng C.A. Meyer
Common Constituents: Ginsenosides (Rb1, Rg1, Re, Rd), polysaccharides, volatile oils, peptides, flavonoids
Solvents: Water or ethanol (residual levels dependent on manufacturing process)
Purity: Commonly standardized to 20-80% ginsenosides
Impurities: Trace solvents, moisture, natural by-products from extraction

4. First Aid Measures

Inhalation: Remove from area of exposure, seek fresh air, consult physician if irritation persists
Skin Contact: Wash affected area with soap and water; remove contaminated clothing
Eye Contact: Rinse gently with water for several minutes, remove contact lenses if present
Ingestion: Rinse mouth and seek medical advice if large quantities swallowed or symptoms occur
Symptoms: Coughing, irritation, redness, mild allergic responses in sensitive individuals

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water, foam, dry chemical, or CO2
Hazardous Combustion Products: May generate carbon oxides, nitrogen oxides, and small molecules from organic breakdown
Protective Equipment: Standard firefighter equipment, self-contained breathing apparatus recommended for heavy smoke
Special Precautions: Dust clouds may cause explosion hazard if dispersed in air, avoid strong airflow

6. Accidental Release Measures

Personal Precautions: Wear gloves, safety goggles, dust masks or respirators
Containment: Avoid dust generation, close sources of ignition, ventilate area
Environment: Stop spill from entering waterways, collect with non-sparking tools
Clean-up Methods: Sweep up gently, use dust suppressant, dispose in sealed container
Waste Disposal: Dispose of according to local, state, or national regulations

7. Handling and Storage

Handling: Avoid breathing dust, prevent contact with eyes and skin, wear PPE as routine
Safe Practices: Keep eating, drinking, and smoking away from work area
Storage: Store in air-tight containers in cool, dry, well-ventilated areas away from direct sunlight, sources of ignition, strong oxidizers
Incompatible Materials: Avoid strong acids, alkalis, oxidizing agents
Shelf Life: Typically maintains quality for two years if sealed and stored correctly, but this can vary with humidity and temperature swings

8. Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation for powder handling or transfer
Protective Equipment: Gloves of nitrile or latex, certified dust mask (N95 or equivalent), safety goggles
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing and wash before reuse
Exposure Limits: No established occupational exposure limits for ginsenosides, treat like nuisance dust
Environmental Control: Implement measures to minimize release to environment, such as filtration or containment during processing

9. Physical and Chemical Properties

Appearance: Yellow-brown to light tan powder, varies with extraction method
Odor: Characteristic slightly sweet, earthy scent
pH: 4.5–7 when dissolved in water, depending on extract composition
Solubility: Soluble in water and ethanol, insoluble in most non-polar solvents
Bulk Density: 0.3–0.45 g/cm³
Melting Point: Degrades before melting, since it is a botanical blend
Boiling Point: Not applicable in pure powder form
Flash Point: Not readily flammable but can generate dust clouds

10. Stability and Reactivity

Chemical Stability: Stable at room temperature and standard humidity, loses potency faster in heat/moisture
Conditions to Avoid: Excess heat, open flame, prolonged exposure to light, moist environment
Materials to Avoid: Strong acids, caustic bases, strong oxidizers
Hazardous Decomposition: Combustion releases organic fumes, carbon monoxide, carbon dioxide
Reactivity: Does not react violently under standard handling

11. Toxicological Information

Acute Toxicity: Low oral toxicity in animal and human studies, with effects largely limited to gastrointestinal upset at high doses
Irritation: Mild skin and respiratory irritation possible with dust exposure
Allergenic Potential: Rare, but sensitive individuals may develop allergy-like symptoms or rash
Repeated Dose Toxicity: No evidence of serious long-term toxicity at dietary supplement doses
Carcinogenicity/Mutagenicity: Not listed by IARC, NTP, or OSHA as carcinogenic
Reproductive Effects: Animal studies show possible hormonal impacts at high levels, consult healthcare provider for use during pregnancy/lactation

12. Ecological Information

Aquatic Toxicity: No evidence of significant toxicity to fish or aquatic invertebrates in standard concentrations
Biodegradability: Expected to break down naturally but bulk release can raise BOD in water sources
Persistence: Plant-based and breaks down in typical wastewater systems
Bioaccumulation: Not anticipated based on plant chemistry, no data supporting risk in food chain
Soil Impact: Rapidly degrades in soil, no long-term residue expected

13. Disposal Considerations

Waste Treatment: Follow all regional, national, and local laws
Safe Methods: Place in a sealed bag or container, do not release large amounts into drain or environment
Special Handling: Avoid generating dust, may dispose as non-hazardous organic waste where permitted
Hazardous Waste Status: Usually not classified as hazardous, but extract with solvents should follow strict procedures

14. Transport Information

UN/NA Number: Not regulated as a dangerous good
Transport Hazard Class: None assigned
Packing Group: None assigned
Labelling Requirements: No special labelling needed under GHS or ADR regulations
Shipping Method: Standard containers, protect from moisture and heat during transit
Special Provisions: Secure sealed container, provide proper documentation for customs if exported

15. Regulatory Information

Inventory Status: Listed in many countries as a food, cosmetic, or supplement ingredient; subject to differing standards (e.g., FDA, EFSA)
GHS Labelling: Not classified as hazardous
Workplace Regulations: Follow standard worker protection rules for botanical powders
Restrictions: May require proof of non-GMO or organic sources in some markets
Other Information: Regularly review national and local laws relating to plant-derived herbal ingredients, as herbal regulations change and can impact import/export