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Material Safety Data Sheet (MSDS) for Oligosaccharides

Identification

Product Name: Oligosaccharides
Chemical Family: Carbohydrates
Recommended Use: Food additive, prebiotic ingredient, pharmaceutical excipient
Manufacturer: Supplier contact information must list name, address, phone number
Emergency Telephone: National emergency numbers, local poison control centers
Synonyms: Not limited to fructooligosaccharides, galactooligosaccharides, inulin-type oligosaccharides
CAS Number: Reputable sources such as PubChem or ChemSpider provide this detail for specific types

Hazard Identification

GHS Classification: Not considered hazardous under GHS regulations for most oligosaccharides
Pictogram: No pictograms assigned
Signal Word: Not required under standard classification
Hazard Statements: None expected with normal handling
Precautionary Statements: Avoid inhalation of dust, minimize direct contact with eyes and open wounds
Potential Health Effects: Mild irritation possible if inhaled as dust or when in contact with eyes

Composition / Information on Ingredients

Chemical Name: Oligosaccharide (types vary: fructooligosaccharide, galactooligosaccharide, inulin, etc.)
Concentration: Purity usually exceeds 90% in food or pharma grade preparations
Other Components: Moisture content, trace minerals, and protein residues can be present at less than 5%
Impurities: Residual sugars such as glucose, fructose, galactose at low ppm levels

First Aid Measures

Inhalation: Move to fresh air if dust causes respiratory discomfort; seek medical attention for persistent symptoms
Eye Contact: Rinse eyes gently with water for at least fifteen minutes; remove contact lenses if safe
Skin Contact: Wash with mild soap and water; irritation rarely proceeds beyond mild redness
Ingestion: Rinse mouth thoroughly if large amounts swallowed; consult a health professional if digestive upset persists

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, foam
Protective Equipment: Firefighters use NIOSH-approved self-contained breathing apparatus
Specific Hazards: Fine dust may form explosive mixtures with air when concentrations rise
Decomposition Products: Burning can release carbon monoxide, carbon dioxide, small molecule aldehydes
Special Procedures: Evacuate area, cool closed containers exposed to flame with water

Accidental Release Measures

Personal Precautions: Avoid dust formation, ventilate area if cloud develops, use personal protective gear
Environmental Precautions: Prevent run-off into surface waters, avoid sweeping large amounts into drains
Cleanup Methods: Use vacuum fitted with HEPA filter, or dampen and sweep; bag for safe disposal
Disposal of Residues: Collect residues and contaminated sweepings for disposal as non-hazardous waste

Handling and Storage

Precautions for Safe Handling: Use local exhaust ventilation to control airborne dust, avoid creating dust clouds, do not eat, drink, or smoke in handling areas
Storage Conditions: Keep container tightly closed, store in cool, dry, well-ventilated room, protect from moisture
Incompatible Materials: Strong oxidizing agents, excessive humidity accelerates degradation
Packing Materials: Store in food-grade, airtight containers to prevent cross-contamination or caking

Exposure Controls and Personal Protection

Occupational Exposure Limits: Oligosaccharides do not carry established TLVs, but general dust nuisance limits apply (e.g., OSHA PEL 15 mg/m³ for total dust)
Engineering Controls: Local exhaust ventilation, process enclosure, routine housekeeping
Personal Protective Equipment: Safety glasses, gloves made from natural or synthetic rubber, dust masks or N95 respirators, protective clothing when handling bulk forms
Hygiene Measures: Wash hands after use, change contaminated clothing before leaving the facility

Physical and Chemical Properties

Appearance: White to off-white powder, sometimes granular
Odor: Odorless or slightly sweet
Odor Threshold: Not applicable
pH (in solution): 4.0 – 7.0 for aqueous solutions (10% w/v)
Melting Point/Freezing Point: Decomposes before melting
Boiling Point: Not applicable
Flash Point: Not flammable in standard conditions
Evaporation Rate: Not volatile
Flammability (solid/gas): Can support combustion in the presence of strong ignition source as dust cloud
Vapor Pressure: Negligible
Relative Density: 1.45 – 1.6 g/cm³
Solubility: Highly soluble in water, almost insoluble in organic solvents
Partition Coefficient: Not determined
Auto-Ignition Temperature: More than 350°C
Decomposition Temperature: From 150°C (decomposition products increase above 200°C)
Viscosity: Not applicable in powder form

Stability and Reactivity

Chemical Stability: Stable under recommended conditions of storage and use
Possible Hazards: Excess moisture encourages caking and microbial growth
Reactivity: Non-reactive at room temperature with typical food or pharmaceutical ingredients
Conditions to Avoid: Prolonged exposure to heat, direct sun, high humidity
Incompatible Materials: Strong oxidizers
Hazardous Polymerization: Does not occur
Decomposition Products: Carbon oxides, water vapor, possible furans or aldehydes with high heat

Toxicological Information

Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Effects: Low acute oral and dermal toxicity in animal studies; excessive intake may cause gastrointestinal discomfort (flatulence, bloating, diarrhea)
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity reported in major studies
Skin Sensitization: Not expected based on structure and clinical use
Eyes: Mechanical irritation if dust enters
LD50 (Oral, Rat): Exceeds 20,000 mg/kg; considered non-toxic by ingestion at reasonable levels
Medical Conditions Aggravated: Individuals with preexisting sensitivity to dietary fibers may experience mild digestive upsets

Ecological Information

Ecotoxicity: No data indicates toxicity to aquatic or terrestrial species at predicted environmental release concentrations
Persistence and Degradability: Readily biodegradable; serves as substrate for various soil and water microbes
Bioaccumulative Potential: Minimal, due to rapid metabolism and conversion by flora
Mobility in Soil: High solubility implies rapid dispersion and microbial breakdown
Other Adverse Effects: Not identified at realistic exposure levels; no evidence of groundwater contamination

Disposal Considerations

Product Disposal: Incinerate in approved facility, landfill only according to local regulations
Contaminated Packaging: Rinse containers thoroughly before recycling or reuse if permitted locally
Hazardous Waste Code: Not classified as hazardous waste
Special Precautions: Prevent disposal into sewers and water sources where high organic loading could cause oxygen depletion

Transport Information

UN Number: Not regulated
Transport Hazard Class: Non-hazardous
Packing Group: None assigned
Special Transport Precautions: Use sealed packaging for bulk cargo to avoid dust leakage or product caking
Labels: Not required for routine land, sea, or air transport under UN/IMDG/ICAO rules
Environmental Hazards: Not considered an environmental hazard during transportation

Regulatory Information

International Regulation: Not listed on major chemical control schedules (e.g., REACH, TSCA, DSL)
OSHA: Considered a nuisance dust only
EPA: Exempt from tolerance as food substances
FDA: Approved as GRAS (Generally Recognized as Safe) for direct addition to food
EU Food Additive Regulation: Permitted for use as prebiotic, dietary fiber source
Labeling Requirements: List as ‘oligosaccharide’ or specific functional carbohydrate under nutrition regulations