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Product Name: Nicotinamide
Chemical Name: Pyridine-3-carboxamide
Other Names: Niacinamide, Vitamin B3 amide
CAS Number: 98-92-0
Recommended Use: Used in food supplements, pharmaceuticals, cosmetics, laboratory research
Supplier Details: Manufacturer or distributor address and contact information for emergencies
Emergency Contact: Local emergency numbers or poison control center
Classification: Not classified as hazardous according to GHS criteria
Hazard Statements: May cause slight eye or skin irritation
Pictograms: No pictogram required
Signal Word: None
Precautionary Statements: Avoid inhalation, wash hands thoroughly after handling, avoid contact with eyes
Routes of Exposure: Inhalation, ingestion, skin, eyes
Specific Hazards: Dust generation can cause mechanical irritation
Chemical Identity: Nicotinamide
Synonyms: Niacinamide
Formula: C6H6N2O
Content: 99–100% pure substance
Impurities: May contain trace organic or inorganic residues depending on source, typically negligible for lab and food quality
Inhalation: Move person to fresh air, seek medical attention if breathing becomes difficult
Skin Contact: Wash affected skin with mild soap and water, remove contaminated clothing
Eye Contact: Rinse eyes carefully with plenty of water for several minutes, consult a physician if irritation continues
Ingestion: Rinse mouth, drink water if conscious, contact medical professionals for persistent symptoms
Advice for Doctor: Treat symptomatically based on patient’s condition
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Special Hazards: During fire, may emit oxides of carbon and nitrogen
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing
Special Procedures: Prevent runoff from entering drains or water sources, use water spray to cool fire-exposed containers
Personal Protection: Wear suitable gloves, goggles, dust mask if significant dust is present
Spill Cleanup: Sweep up material, avoid creating airborne dust, transfer to recovery or disposal container
Environmental Precautions: Do not release to surface water or soil, prevent dust spread
Decontamination: Ventilate area after cleanup, wash spill region with water and mild detergent
Handling: Handle in well-ventilated area, avoid inhaling dust, avoid eye and skin contact, keep containers tightly closed
Storage: Store in cool, dry, well-ventilated area away from strong oxidizing agents, moisture, and direct sunlight
Precautions: Keep away from food and beverages, use proper transfer equipment to minimize spillage
Exposure Limits: No occupational exposure limit established for nicotinamide
Engineering Controls: Use local exhaust or process enclosure to control dust, maintain clean workspaces
Eye Protection: Safety goggles or face shield
Skin Protection: Lab coat, protective gloves resistant to chemicals
Respiratory Protection: Suitable dust mask if powder is airborne
Hygiene Measures: Wash hands and face before eating, drinking, or smoking; remove contaminated clothing
Appearance: White, crystalline powder
Odor: Odorless or faint characteristic
Molecular Weight: 122.13 g/mol
pH: 6–7 (5% solution in water)
Melting Point: 128–131°C
Boiling Point: Decomposes before boiling
Flash Point: Not combustible
Solubility: Easily soluble in water, slightly soluble in ethanol, insoluble in ether
Density: About 1.40 g/cm³
Partition Coefficient: logP = –0.37
Other Properties: Stable under normal conditions with routine storage
Chemical Stability: Remains stable under recommended conditions
Conditions to Avoid: Moisture, excess heat, exposure to strong oxidizing agents
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: May form oxides of carbon and nitrogen with extreme heat or combustion
Hazardous Reactions: Does not polymerize, no unusual reactivity noted under normal handling
Acute Toxicity: Oral LD50 in rats greater than 3500 mg/kg
Chronic Effects: High doses over time may cause liver effects, skin flushing, nausea
Routes of Exposure: Ingestion, inhalation, skin, eyes
Symptoms: Large oral doses may cause dizziness, headache, mild gastrointestinal distress
Cancer Risk: Not classified as carcinogenic by major agencies
Mutagenicity: No data indicating mutagenicity
Reproductive Toxicity: No known reproductive toxicity
Aquatic Toxicity: Not expected to be hazardous to the aquatic environment
Mobility: Water soluble, likely mobile in environment
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulative Potential: Not expected to bioaccumulate (low logP value)
Other Hazards: Not expected to pose environmental risk at low concentrations
Disposal Methods: Dispose in accordance with local, regional, and national regulations
Chemical Waste: Place unused or waste material in labeled containers for authorized chemical disposal
Packaging: Dispose of contaminated packaging via licensed waste contractor
Precautions: Prevent material from entering waterways or drains during disposal
UN Number: Not regulated
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: None known during transport
Transport Precautions: Ship in tightly sealed containers, prevent spillage, follow routine transport practices
GHS Labeling: Does not require hazard label for most applications
Inventory Listing: Included in TSCA (US), EINECS (EU), AICS (Australia), DSL (Canada), ENCS (Japan)
SARA Title III: Not listed as a reportable substance
Other Regulatory Notes: Nicotinamide qualifies as a food additive or supplement under relevant food and drug regulations in many countries; workplace use mandates adherence to occupational safety and health standards
Workplace Safety: Refer to OSHA, WHMIS, REACH as relevant for the region or country
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
