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Material Safety Data Sheet: Natural Beta Carotene

Identification

Substance Name: Natural Beta Carotene
Chemical Formula: C40H56
Synonyms: Provitamin A, Carotene
CAS Number: 7235-40-7
Application: Used in food coloring, nutritional supplements, animal feed, cosmetics
Manufacturer: Contact supplier for full address, emergency contact information
Emergency Number: Local poison control or manufacturer emergency line
Product Type: Organic pigment, crystalline powder or oily suspension
Recommended Use: Additive, antioxidant, precursor to Vitamin A

Hazard Identification

Hazard Classification: Not classified as hazardous in standard concentrations for food or feed use
Potential Health Effects: May irritate eyes and respiratory tract as dust; non-toxic in expected usage levels
GHS Pictograms: None required for non-industrial use
Signal Word: None
Precautionary Statements: Use proper ventilation, avoid generating dust, minimize skin and eye contact
Routes of Exposure: Inhalation (dust), eyes, ingestion
Long-Term Effects: Large doses may cause yellowing of the skin (carotenodermia), not harmful and reversible
Other Hazards: Combustible dust under certain conditions, may form explosive mixtures with air in powder form

Composition / Information on Ingredients

Main Ingredient: Beta Carotene (C40H56): Typically 85-99% by weight
Other Components: May include vegetable oil (sunflower, corn, palm), silicon dioxide, tocopherols (natural vitamin E as antioxidant), minor carotenoids (alpha-carotene, lutein)
Impurities: No known hazardous impurities at levels present
Molecular Weight: 536.87 g/mol

First Aid Measures

Inhalation: Move person to fresh air. Seek medical attention if symptoms like coughing or shortness of breath persist.
Eye Contact: Rinse eyes gently with water for at least 15 minutes while holding eyelids open. Seek medical advice if irritation persists.
Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing and wash before reuse.
Ingestion: Rinse mouth, drink water. No significant harm expected, but consult physician for large quantities or persistent discomfort.
Special Notes: No specific antidote. Treat symptomatically. Product color may temporarily stain skin or mucous membranes.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical powder, or carbon dioxide
Special Hazards: Fine dust can form explosive mixtures with air. Product may release acrid smoke and irritating gases in fire (carbon oxide compounds).
Protective Equipment: Firefighters wear self-contained breathing apparatus and protective gear.
Firefighting Instructions: Avoid inhaling combustion products. Cool exposed containers with water spray. Prevent run-off into drains.
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, possible hydrocarbon fragments.

Accidental Release Measures

Personal Precautions: Wear dust mask, protective eyewear, gloves. Avoid breathing dust. Ventilate area.
Environmental Precautions: Prevent spilled material from entering water sources, drains, or soil.
Methods of Cleaning Up: Sweep up using non-sparking tools. Collect spillage for disposal. Remove trace amounts with damp cloth or mop to avoid raising dust.
Other Notes: May stain surfaces. Dispose of collected waste in line with local environmental regulations.
Disposal of Contaminated Material: Store collected waste in sealed containers until disposal.

Handling and Storage

Precautions for Safe Handling: Minimize dust generation. Use protective equipment during bulk handling or mixing. Wash hands before eating, drinking, or touching face.
Storage Conditions: Store in original, tightly sealed containers away from strong light, air, and heat. Keep in a cool, dry, well-ventilated area.
Incompatibilities: Strong oxidizing agents, concentrated acids and alkalis, direct exposure to sunlight.
Special Requirements: Protect from moisture. Use nitrogen flush if container is opened repeatedly.
Shelf Life: Stability best maintained below 25°C, protected from oxygen and light.

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limits for beta carotene.
Engineering Controls: Use local exhaust ventilation systems for bulk and powder operations.
Personal Protective Equipment: Respiratory: Dust mask for airborne dust;
Eye: Safety goggles;
Skin: Gloves and lab coat or work clothing;
Hygiene Measures: Wash hands thoroughly after handling. Avoid ingesting, inhaling, or touching eyes. Do not eat or drink in work area.

Physical and Chemical Properties

Appearance: Orange-red crystalline powder or oil suspension
Odor: Odorless to faintly sweet
Solubility: Practically insoluble in water, soluble in fats/oils and organic solvents (chloroform, acetone, hexane)
Melting Point: 176-180°C (crystalline form)
Boiling Point: Decomposes before boiling
Vapor Pressure: Negligible
pH: Not applicable (non-aqueous)
Density: About 1.0-1.1 g/cm³ (varies with formulation)
Partition Coefficient (n-octanol/water): High (log Kow >10)
Flash Point: Data not available, but dust can be combustible
Auto-Ignition Temperature: Not established for pure compound
Stability: Sensitive to oxidation, light, heat

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: May react with strong oxidizers
Conditions to Avoid: High temperature, direct sunlight, oxygen, moisture
Materials to Avoid: Peroxides, strong acids or bases
Hazardous Decomposition Products: Carbon oxides, various hydrocarbons
Polymerization: Will not occur under normal conditions

Toxicological Information

Acute Toxicity: Oral LD50 (rat): >10,000 mg/kg, essentially non-toxic
Chronic Toxicity: No evidence for carcinogenicity, teratogenicity, or reproductive toxicity in humans at dietary levels
Routes of Exposure: Oral, inhalation, skin, eye
Symptoms of Exposure: High intake can cause skin discoloration (carotenodermia), reversible on discontinuation; no clinical harm noted
Inhalation: May cause transient mild respiratory irritation if dust is inhaled
Skin/Eye: May cause slight irritation in sensitive individuals
Mutagenicity: Not mutagenic in standard assays
Carcinogenicity: Not listed by IARC, NTP, OSHA
Other Toxicological Effects: Excessive consumption linked to increased lung cancer risk in heavy smokers; normal dietary intake considered safe

Ecological Information

Ecotoxicity: Beta carotene is readily biodegradable. Not expected to be harmful to aquatic or terrestrial organisms at normal release levels.
Persistence and Degradability: Breaks down rapidly in environment under sunlight and microbial action
Bioaccumulation: Unlikely, high fat solubility but extensively metabolized in most organisms
Mobility in Soil: Low mobility due to strong adsorption to soil particles and rapid degradation
Aquatic Toxicity: No data identifying significant risk to aquatic life at realistic concentrations
Other Adverse Effects: No known environmental hazards in customary use patterns

Disposal Considerations

Waste Management: Safely dispose as non-hazardous organic waste, unless contaminated by dangerous substances
Disposal Methods: Incinerate in accordance with local, regional, and national regulations or landfill as appropriate
Container Disposal: Rinse thoroughly before reuse or recycling; crush or puncture before landfill disposal to prevent unauthorized use
Environmental Precautions: Avoid release into surface waters, soil, and sewage systems in large amounts
Additional Notes: Compliance with regional waste control authorities needed

Transport Information

UN Number: Not regulated for ground, air, or sea transport
Proper Shipping Name: Natural Beta Carotene
Transport Hazard Class: Non-hazardous
Packing Group: Not applicable
Special Transport Precautions: Protect from moisture, strong light, extreme temperatures. Seal packaging securely.
Labels: No transport labels required
Handling During Transport: Avoid excessive crushing or shaking, keep away from incompatible materials

Regulatory Information

TSCA Status: Listed
EU Directive 67/548/EEC: Not classified as dangerous
OSHA Hazard Communication Status: Exempt as food additive, not considered hazardous under normal use
Inventory Status: Registered and approved by major chemical inventories
GMO Status: Non-GMO as sourced from natural origins unless otherwise stated
Food Additive Approval: Recognized as GRAS (Generally Recognized As Safe) by US FDA, EU, and other international bodies for intended use
Other Regulatory Listings: Meets purity and safety requirements of FAO/WHO Codex Alimentarius, JECFA, EFSA
Labeling Requirements: Follows food safety, chemical labeling, and transport standards for ingredient identification, batch, and expiry