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Material Safety Data Sheet: Monocaprylin

Identification

Product Name: Monocaprylin
Chemical Name: Glyceryl monocaprylate
CAS Number: 26402-26-6
EC Number: 247-668-1
Recommended Use: Emulsifier, excipient, surfactant in pharmaceuticals, food, and cosmetics
Manufacturer/Supplier: Contact information available through standard directories; emergency phone numbers provided by local regulatory authorities.

Hazard Identification

Classification: Not classified as hazardous under GHS criteria
Physical Hazards: May generate slippery conditions if spilled
Health Hazards: May cause mild skin or eye irritation in sensitive individuals
Environmental Hazards: Minimal impact expected; not classified as dangerous for the environment
Signal Word: None required
Pictograms: None applicable

Composition / Information on Ingredients

Main Component: Glyceryl monocaprylate
Synonyms: 1-Monooctanoin, Monooctanoin
Purity: >90%
Impurities: Glycerol, caprylic acid, other mono- and diacylglycerols present in trace amounts

First Aid Measures

Inhalation: Move person to fresh air; seek medical advice if symptoms persist
Skin Contact: Wash skin thoroughly with soap and water; remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes; medical attention recommended if irritation persists
Ingestion: Rinse mouth with water; seek medical advice if symptoms occur

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, CO₂, water spray
Unsuitable Extinguishing Media: Water jet may spread product
Specific Hazards: May produce toxic fumes (acrolein) on thermal decomposition
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and protective clothing
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, acrolein, other irritating vapors

Accidental Release Measures

Personal Precautions: Use personal protective equipment; avoid contact with eyes and skin
Environmental Precautions: Prevent entry into waterways and drains
Clean-Up Methods: Absorb spilled liquid with inert material (sand, earth); collect in appropriate, labelled containers for disposal; clean spill area with detergent and water to remove residues
Reference to Other Sections: Refer to exposure controls, disposal considerations

Handling and Storage

Precautions for Safe Handling: Use in well-ventilated areas; avoid ingestion and contact with eyes or prolonged skin contact; wash hands after handling
Storage Conditions: Store in tightly closed container in a dry, cool, well-ventilated place away from incompatible materials (strong oxidizers); keep container upright to prevent leakage
Incompatible Materials: Strong oxidizing agents, acids

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for monocaprylin
Engineering Controls: Ensure adequate ventilation, especially in confined areas
Personal Protective Equipment: Wear protective gloves and safety goggles; laboratory coats or protective clothing recommended
Hygiene Measures: Wash hands, forearms, and face thoroughly after handling; do not eat or drink in work areas

Physical and Chemical Properties

Appearance: Colorless to pale yellow oily liquid or soft solid
Odor: Faint, characteristic
Boiling Point: Above 270°C (estimated)
Melting Point: 25–30°C (varies with purity)
Solubility: Insoluble in water; soluble in alcohols and organic solvents
Flash Point: 170–180°C (closed cup, estimated)
Vapor Pressure: Negligible at ambient conditions
Density: 0.95–0.98 g/cm³
Viscosity: Moderately viscous at room temperature
Partition Coefficient (log Kow): 3–5 (estimated)

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Conditions to Avoid: Excess heat, open flames, prolonged exposure to air
Incompatible Materials: Strong oxidizing agents
Hazardous Decomposition Products: Thermal decomposition produces carbon monoxide, carbon dioxide, and traces of acrolein
Polymerization: Will not occur

Toxicological Information

Acute Toxicity: Oral LD₅₀ (rat): >5000 mg/kg; low toxicity
Skin Irritation: Mild, transient effects possible with prolonged exposure
Eye Irritation: Mild, transient effects observed in some laboratory tests
Respiratory Irritation: Minimal risk; vapor pressure negligible
Carcinogenicity: Not considered carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of adverse reproductive effects
Mutagenicity: Not mutagenic in in-vitro studies

Ecological Information

Aquatic Toxicity: Not expected to cause harm at low concentrations
Persistence and Degradability: Readily biodegradable in standard environmental conditions
Bioaccumulation Potential: Low potential due to metabolic breakdown
Mobility in Soil: Low, product is hydrophobic and likely adheres to soil particles
Other Adverse Effects: No data indicating significant impacts to terrestrial or aquatic life

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, state, and federal regulations; incineration or controlled landfill recommended
Container Disposal: Empty containers should be triple-rinsed before recycling or landfill disposal
Precautions: Do not release into the environment; avoid contaminating water supplies or soil during disposal

Transport Information

UN Number: Not regulated
Proper Shipping Name: Not classified as hazardous for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions for User: Avoid large-scale spills in transit; keep container upright and closed during transport

Regulatory Information

US TSCA: Listed
EU REACH: Registered or exempted
OSHA Hazard Communication: Not regulated as a hazardous chemical
Other Regulations: Not subject to specific labelling or restrictions under current international chemical control laws
WHMIS Classification (Canada): Not controlled
California Proposition 65: Product does not contain chemicals known to cause cancer or reproductive toxicity