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Methylcellulose MC: Weaving Science Into Everyday Life

Historical Threads: From Cotton to the Lab

Methylcellulose didn't pop up in kitchens and factories overnight. Its story starts deep in the 20th century, not long after early chemists figured out how to break down and rebuild cotton and wood fibers. As cities industrialized, demand for reliable thickeners, stabilizers, and binders soared. German chemists first prepared methylcellulose by treating cellulose—found in everything from wood pulp to pure cotton—with methyl chloride. This early work unlocked the door to a family of cellulose ethers that found quick utility wherever consistency and thickness mattered. More than a century later, methylcellulose shoulders much of the heavy lifting in construction, food, and pharmaceuticals, shaping textures and solving tricky formulation problems that old-school ingredients just couldn't handle.

Product Snapshot: What Sets Methylcellulose Apart

Methylcellulose powders look simple—off-white, sometimes a little granular—but this material rarely stands alone. Manufacturers supply MC in a variety of grades, all depending on how many methyl groups hang off its cellulose backbone and how finely the powder flows. Each batch carries its own calling card based on viscosity and purity. Food-grade and pharma-grade MC ship out with paperwork, traceability, and shelf life guarantees. Building contractors reach for technical-grade MC that flows well into dry mortar without the intense purification demanded by drugmakers. Brands compete with small tweaks in particle size, viscosity range, and purity, but most of the world’s methylcellulose ends up as a white or pale powder just begging to be explored by anyone interested in the science of goo and gel.

The Science Stuff: Physical & Chemical Traits

Open a fresh bag of methylcellulose and you’ll find a white, almost fluffy powder with little odor or taste. It won’t dissolve straight into ice-cold water, but a few minutes of stirring and gentle warming coax it into a perfectly smooth, almost clear solution. The real trick in using MC lies in how temperature flips the script—hot water pushes MC chains together, forming a gel, while cool water lets those chains fan out and slip past each other. Chemically, the structure relies on cellulose from plant cell walls, modified with methyl groups that block water from breaking the polymer down. MC powders show low toxicity, don’t burn easily, and won’t rot away like untreated wood pulp. Each manufacturer tests viscosity, moisture, pH, and heavy metal content, keeping suppliers and regulators confident it does exactly what it’s supposed to do.

Specs and Standards: Labels Matter

Every package of methylcellulose reports detailed technical specifications. Viscosity jumps out first—many food or drug uses call for a very narrow range, sometimes as tight as 15 to 500 centipoise measured at a certain concentration and temperature. Moisture content, purity levels, and typical particle size round out the specs. Food-grade and pharma-grade MC follow strict international standards. Reputable suppliers run tests for heavy metal contamination, microbial load, and solvent residues. The world’s main chemical registries list methylcellulose with unique numbers; anyone mixing or selling it for food or medicine must follow clear labeling rules under the eyes of global watchdogs like the FDA and European Food Safety Authority.

How People Make Methylcellulose

Manufacturers start with cellulose from trees or cotton. They alkalize this raw material—mix it with sodium hydroxide—then react it with methyl chloride gas under careful control. This tunes the number of methyl groups added, directly affecting water solubility, gel strength, and viscosity. The resulting goopy mass gets neutralized, washed, dried, and milled into a fine, stable powder. Good quality control checks the substitution level and removes leftover salts or byproducts. The process requires strong chemical handling know-how, air management, and waste recovery, but decades of engineering tweaks have made large-scale MC production predictable and safe.

Beyond Basics: Chemical Reactions & Modifications

Tinkerers keep finding ways to upgrade the basic MC structure. Sometimes they blend MC with other cellulose ethers for better workability in dry mix mortars or to boost freeze-thaw stability in frozen foods. Some labs graft extra groups onto MC molecules, making them swell more in water or stick to specific surfaces. These tweaks let MC perform in new settings, like film coatings, battery electrodes, or specialty adhesives. Chemical reactions usually play it gentle; strong bases and acids can break MC down, but most day-to-day recipes stick to physical mixing and mild pH tweaks. Additives like salts or sugar change gelation temperature, unlocking even more versatility in food and industry.

Synonyms & Trade Names: Methylcellulose’s Identity Parade

Ask around and you’ll hear methylcellulose called a dozen names. Scientists jot down “MC,” “cellulose methyl ether,” or just “methylated cellulose.” Big brands sell it under names like Methocel, Celacol, and Tylose, each touting minor differences in grade or purity. Technical data sheets reference various CAS numbers, and buyers demand to know which international pharmacopeia a supplier follows. Cut through the marketing, and almost all these products share a common chemistry—powdered MC, ready to serve as thickener, binder, or film former.

Staying Safe: Rules on Handling and Using MC

Manufacturers design MC for predictable, low-toxicity behavior. Food-grade MC comes with allergen and GMO statements, lot traceability, and microbe counts. Bulk shippers move it in sealed bags or drums to keep moisture and contaminants out. Factories that handle MC run dust controls because breathing fine powders never does lungs any favors. Good ventilation, dust masks, and basic hygiene go far. Regulatory agencies set clear allergen, heavy metal, and purity limits for each application. Environmental rules handle MC as a low-hazard substance—leftover wastes break down slowly, but don’t harm waterways or soil when disposed of correctly.

Where People Use MC: Everyday and Industry Applications

Home cooks rarely hear the name methylcellulose, but they swallow tiny doses in thickened drinks, whipped toppings, and reduced-fat salad dressings. MC gels play a quiet but essential role in gluten-free baking, pie fillings, and vegan cheeses, keeping moisture locked in and structure stable. Pharmaceutical firms lean heavily on MC for tablet coatings—so the pill survives a humid factory, ships cross-country, and only dissolves in the right spot inside your body. Construction workers mix MC powders into wall plasters and tile adhesives because it holds water and prevents premature curing. Cosmetic labs use it for creamy lotions and stable shampoos. MC even ends up as a mock egg white in culinary foams or soufflés, letting chefs ditch eggs and still wow their guests. Some specialized MC grades show up in oil drilling fluids and 3D printing pastes.

Research & Development: Pushing Boundaries

Scientists never stop hunting for new textures, temperatures, or specialties in methylcellulose. Some teams probe MC’s gelation for food with lower fat or better freeze-thaw performance. Pharmaceutical technologists work on MC blends for advanced controlled-release capsules, customizing how drugs disperse through the gut. In biotechnology labs, MC solutions create scaffolds for cell culture or tissue regeneration, mimicking the softness of living matter. Environmental researchers explore using MC-encapsulated particles for slow-release fertilizers and eco-friendly pesticides. Collaborations between research universities and manufacturers keep unlocking tweaks to molecular weight, substitution pattern, and mixability—all driving methylcellulose into tomorrow’s applications.

Toxicity and Safety Research

Decades of animal and clinical studies back up methylcellulose’s solid safety record. The body sees MC as a kind of dietary fiber; most passes through the gut unchanged, with no detectable absorption or buildup. Clinical trials and regulatory reviews show MC rarely triggers allergies, and even like doses much larger than normal don’t stress kidneys or the immune system. Agencies worldwide set upper intake limits that keep a wide health margin. Some isolated reports have described GI upset at large doses, tied to MC’s indigestible nature and water-holding power. The compound neither encourages nor blocks absorption of nutrients, so nutrition scientists consider it inert. Industrial hygiene researchers focus on dust safety during processing—notably in plants and labs—but MC powders do not carry the same hazard flag as other synthetic polymers.

Future Prospects: Methylcellulose Moves Forward

Methylcellulose stands in a sweet spot: made from renewable plant resources, loaded with customization tricks, and compatible with green production strategies. Future attention likely falls on ways to lower the carbon footprint of MC production, improve recycling of processing byproducts, and chase new functionalities with fewer chemicals. As consumers push for transparency in food and drugs, suppliers invest in cleaner, traceable supply chains for food-grade and pharma MC. In the lab, MC may keep supporting regenerative medicine, wound healing gels, edible coatings for food preservation, and sustainable packaging. The renewable backbone paired with decades of safety and practical flexibility keeps methylcellulose at center stage for companies aiming to replace petroleum-based chemicals or animal-derived thickeners with something both science-backed and nature-derived.




What is Methylcellulose MC used for?

Everyday Uses That Go Unnoticed

Most people never hear about methylcellulose, but trace its path into daily life and it quickly becomes clear why this compound draws respect from chemists and cooks alike. I remember opening a box of instant mashed potatoes and seeing the ingredient list—there it was, just another line among flour and salt. Methylcellulose keeps foods from falling apart or becoming clumpy, giving meals that lively texture we look for in the food we eat.

Food Industry Says Thanks

Makers of plant-based meats know methylcellulose as the “magic glue” that keeps burgers juicy and slices of vegan sausage firm after a trip to the skillet. Unlike some fillers or gums, it naturally gels when heated, helping patties hold together when chefs cook them. Once things cool down, methylcellulose “lets go” and the food softens a bit. This trick separates the real stars of the vegan aisle from bland, crumbly failures and helps diners with dietary restrictions enjoy a better meal.

Fast food chains and food tech companies lean on this property to deliver consistency. Their R&D teams select methylcellulose because it resists spoilage, doesn’t react much with other ingredients, and gets approval from food safety regulators. Its safety record holds strong—experts at the US FDA and the European Food Safety Authority agree on its reliability. After decades of use, clear links to health issues just aren’t there in the research.

More Than Just Food

It might surprise most folks how common methylcellulose has become outside the kitchen. Head into any pharmacy, pick up a box labeled “bulk-forming laxative,” and there’s that same compound again. Most stool softener pills and powders include it because it absorbs water and swells, which helps with constipation. Doctors trust methylcellulose because it works gently, pushing things along without harsh chemicals.

In my first job at a hardware store, I helped a customer find wallpaper adhesive—once again, methylcellulose stood out as the key. It keeps wall coverings up for years and prevents those dreaded air bubbles in the middle of the room. Paint manufacturers slip it into latex formulas to thicken and stabilize. In paper mills, it helps in the delicate process of forming sheets. Even in the realm of eye care, some artificial tear drops contain this cellulose derivative for soothing dry eyes.

Why All This Matters

People notice a difference when methylcellulose does its work. Chefs care about mouthfeel and texture. Patients seek mild solutions over harsh medications. Crafty folks need wallpaper to hang straight, not fall down in humid weather. Methylcellulose gives stability and flexibility to modern products, letting companies deliver predictable results.

As food alternatives and gentle medicines gain ground, transparency and education become even more important. Some worry about “unpronounceable” ingredients, but science backs up methylcellulose as safe when used properly. Brands and experts should reach out and share that knowledge. Rather than hiding in fine print, an open dialogue gives consumers agency and confidence.

Sourcing remains one challenge. Most methylcellulose comes from wood pulp or cotton. Sustainable forestry and transparent supply chains matter just as much as food safety. The industry needs long-term stewardship so future generations can trust their groceries, medicine, and home goods.

While methylcellulose rarely takes the spotlight, life runs smoother, tastier, and more comfortable with it around. Paying attention to these behind-the-scenes helpers means better choices—for diners, patients, and the environment alike.

Is Methylcellulose MC safe for consumption?

A Look at What Methylcellulose Does

Methylcellulose pops up in ingredient lists for all kinds of foods, from veggie burgers to sauces and gluten-free treats. Food manufacturers lean on it for its ability to thicken, bind, and stabilize. The interesting part is that methylcellulose starts as cellulose, which you find in plant cell walls, but then it gets a chemical makeover to become more useful for food processing. It’s not something you’ll find growing in your backyard garden—instead, it’s made using wood pulp or plant fibers in controlled factories. So, is it actually safe for us to eat?

The Science on Safety

My own curiosity led me to look at what experts say. Health agencies worldwide have checked methylcellulose and gave it the green light. The U.S. Food and Drug Administration (FDA) marks it as “Generally Recognized As Safe” (GRAS) when used in reasonable amounts. The European Food Safety Authority (EFSA) reviewed the data and agreed it can go in foods. They both looked at studies where people and animals were given much more than you'd find in a single serving—sometimes many times more—with no toxic effects, allergic reactions, or cancer links showing up.

Researchers tested methylcellulose by giving it to both people and lab rodents. In these trials, most methylcellulose passes through the digestive system without getting absorbed. It doesn’t stick around in organs. It doesn’t break down, so the body treats it sort of like fiber. If anything, eating a lot of it could make some people gassy or cause mild bloating, especially if they don’t usually eat much fiber. But that’s about as serious as the side effects get.

Everyday Use and Practical Concerns

You probably eat tiny amounts of methylcellulose without noticing, especially if you like plant-based foods, low-fat or gluten-free products. I’ve noticed that in my own kitchen, a little bit goes a long way in recipes for homemade veggie patties to keep them from falling apart. It’s vegan-friendly and contains no gluten, dairy, or animal products.

Still, questions come up, like whether it's really necessary to eat foods that include additives like this. Some folks worry about foods with long ingredient lists full of complicated names. Nutrition-wise, methylcellulose doesn’t bring much value since our bodies don’t use it for vitamins or minerals. If you're aiming to eat mostly whole, minimally processed foods, cutting back on additives like methylcellulose makes sense and usually leads to eating more fruits, veggies, and unprocessed grains.

What Should Change?

I’d love to see clearer labeling on packaged foods so shoppers know exactly what’s in their food. Education matters, too—most people don’t know what methylcellulose is. If manufacturers or grocery stores posted simple explainers on why certain additives are included, families could make choices that fit their own health goals and values. Doctors and dietitians can help by keeping up with research and giving personalized advice, especially for people with digestive sensitivities.

The food industry benefits from using methylcellulose for product texture and stability, but balance matters. If food companies keep innovation pointed toward simpler, real-food ingredients and keep portions of additives small, the overall food supply improves. For now, based on research and how people feel after eating it, methylcellulose seems safe in moderation, though choosing whole foods still wins for overall health.

What are the main properties of Methylcellulose MC?

What Methylcellulose Does Best

Methylcellulose stands out in a crowded field of cellulose derivatives. You see it in everything from tiles to tablets, food sauces to industrial glue. A big chunk of its usefulness comes from the unique combo of properties it brings to the table.

Solubility and Gelation

If you’re ever mixed methylcellulose in cold water, you know how easily it dissolves. Unlike most cellulose-based products, MC doesn’t just thicken up right away—it gives you time to blend it in, which cuts down on clumps and lumps. The real surprise comes with heat. Rather than melting, MC actually sets into a gel as the temperature climbs. This reverses most people’s expectations and makes it perfect for food textures—think vegetarian burgers or low-fat sauces. Chefs and scientists alike bank on this heat-gelling action for creative and technical recipes.

Thickening Power and Texture

Cooking and manufacturing both rely on methylcellulose for its reliable thickening action. Unlike starches that can gum up and lose stability, MC keeps mixtures sleek and even. It doesn’t give products a grainy mouthfeel. For pharmaceuticals, that means tablets hold together well. In coatings and adhesives, the thickening helps things go on smooth and stay put.

Film Formation

MC can form films that are both flexible and tough. This isn’t just theoretical—a handful of MC dissolved in water and painted on a surface soon dries into a thin, nearly invisible layer. Food scientists use this property to coat candies or prevent ingredients from sticking. Pharmaceutical companies rely on it for pill coatings that withstand shipping and storage. In the building world, this flexible film helps bind particles but doesn’t crack when pressure or movement happens.

Non-Toxic and Non-Irritating

Methylcellulose appears on many GRAS (Generally Regarded As Safe) lists for food and pharmaceuticals. People sensitive to common allergens don’t run into many problems with MC. I’ve worked with MC-based products in both tablet making and food pilot labs and never experienced skin irritation or unpleasant fumes. This makes manufacturing safer and product recalls rarer.

Chemical Stability and Compatibility

MC resists both acid and alkali attack. It doesn’t degrade easily, and it plays nicely with other substances, from starches to sugars. This helps make sure final products stay effective and appealing from the day they’re packed until they hit a customer’s hands. Some synthetic additives break down or separate, but MC holds its shape and performance for months—sometimes years.

Applications: Meeting Real Needs

Behind every major property of methylcellulose lies a real-world use. In construction, tile adhesives demand a binder that gives workers a smooth spread, doesn’t run, and sets reliably. MC answers all of those requirements. In pharmaceuticals, tablets need to keep from falling apart in the bottle yet break down correctly in the stomach. MC builds that balance. In food, creating meat alternatives that sizzle and sear without falling apart never came easily till methylcellulose arrived.

Potential for Sustainability

MC comes from renewable sources like wood pulp. As more companies aim for greener operations, methylcellulose looks appealing compared to fossil-based additives. I see manufacturers shifting to MC-based thickeners and binders simply to tick sustainability boxes, but they stick with it once they realize the perks for performance and safety.

Looking Ahead: Smarter Use, Better Outcomes

Manufacturers face constant trade-offs between safety, cost, and function. With its broad range of properties, methylcellulose offers a solid choice for everything from dosing accuracy in medicine to reliability in consumer goods. Research continues on tweaking MC’s molecular structure to fine-tune gelation temperatures or thickness, opening new doors for food tech, medicine, and construction.

How should Methylcellulose MC be stored?

Understanding Methylcellulose: An Everyday Perspective

Methylcellulose MC stands out as a core ingredient in pharmaceuticals, food, and even construction fields. People might recognize it as that fine powder in tablet coatings or as a texture enhancer in gluten-free baking. Get this material wet or put it under unusual heat, and the consequences often show up later, either as clumps or as odd smells when someone mixes it into a formula.

Air, Moisture, and Cleanliness: The Enemies Within

Methylcellulose’s worst enemy is moisture. The powder itself looks tough, but it draws in water just by sitting in a humid room. Too much humidity slowly turns it sticky or lumpy. The moment it turns sticky, there’s no real way to turn back the clock and restore it for high-quality use. That’s why a tight, resealable container makes a difference. Some folks might leave a bag just folded down after use, but over time, moisture seeps in. Resealing keeps air and water vapor out, and extends the product’s shelf life.

Temperature and Light: Keeping Cool Pays Off

Heat, though invisible, wrecks methylcellulose by pushing it closer to its gelling point. Warm storage rooms seem like a small problem, but sitting in them for months can kick-start slow changes in structure. Methylcellulose doesn’t smell like much out of the bag, but leave it in the sun for days and those faint odors start creeping in. Sunlight and fluorescent lights both play a role—light-sensitive compounds degrade faster, changing how the material behaves in finished goods. Rolling a container into a dark cabinet or basement, away from any machinery that throws off heat, should become second nature for anyone handling bulk quantities.

Contamination Risks: Clean Storage Tops the List

People sometimes overlook the importance of having a clean and chemical-free environment. Construction workers might pile down bags near paint or solvents—and that’s a huge mistake. Any spilled chemical or even strong-smelling adhesives can gradually affect the powder, simply because the fine particles soak up odors or react with fumes. Food or pharmaceutical grade methylcellulose deserves an extra layer of safety, like sealed secondary packaging or keeping it on clean shelves, far from dust or splash hazards.

Labeling and Shelf Life: Tracking the Details

Every warehouse or lab should have a system to track when methylcellulose comes in and which lot is which. Sticking a date on the container does more than satisfy regulators—it gives staff a fighting chance to use the oldest stock before it loses quality. Manufacturers offer a shelf life, but real-world conditions shorten it or stretch it out. Anything past its date demands a closer look for clumps, discoloration, or a strange smell before someone adds it to any production batch.

Practical Solutions for Daily Use

Smaller packs go faster, meaning less time exposed to air and fewer chances for loss. Staff who work with MC should wear clean gloves and avoid scooping over open containers to reduce cross-contamination. Kitchens may not need dust masks, but in a plant or lab, airborne particles collect quickly and spoil clean powders. Every shift should finish with tightly closed lids, swept floors, and no leftovers outside their packaging.

Why Proper Storage Matters to Everyone

A lot of waste happens when small storage mistakes add up. The cost jumps in lost product and in downtime spent sorting through ruined powder. In my years working with both food and lab grades, storage mistakes cost more than replacement bags alone. Small habits like using extra zipper bags, tracking dates, or wiping down shelves go a long way. The best results come from keeping things simple: keep methylcellulose cool, dry, and covered in a clean space. Results in the finished product always reflect the care people take in the basics.

Can Methylcellulose MC be used in gluten-free recipes?

Making Bread Without Gluten: A Real Challenge

Gluten holds bread and cakes together, so baking without it often leads to crumbly or gummy results. For anyone who’s tried to make a sandwich with gluten-free bread, frustration probably isn’t a stranger. I spent many afternoons wrestling with dough that seemed more suitable for bricks than toast. That’s where methylcellulose, known as MC in food circles, enters the scene.

What Does Methylcellulose Do?

MC acts as a thickener and holds moisture. More importantly, it creates a stretchy, web-like network during baking that traps air. Gluten does the same job in traditional recipes. MC stands out because it gels as it heats up, giving gluten-free dough structure inside a hot oven. This gelling reverses at lower temperatures, so finished bread stays moist instead of bouncing back like rubber.

Why MC Matters in Gluten-Free Recipes

Anyone looking for decent texture in gluten-free bakes eventually comes across gums and fibers. Some—like xanthan or guar—help mix water and oil or slow drying, but they can’t mimic that unique chewiness good bread delivers. MC often lifts results to a new level. I’ve made pizza crusts with and without MC, and the batches with it sliced, folded, and tasted more like the real deal. More than Instagram trend, it answers a need people with celiac disease or wheat allergies face every day.

What Experts and Studies Show

Food scientists put MC through its paces in lab kitchens around the globe. A study in the journal Food Hydrocolloids showed adding MC to rice-based bread produced slices with bigger volume and better crumb. Taste testers picked these samples for being softer and less dry. Reports from recipe developers line up with the science—methylcellulose helps prevent collapsed loaves, gluey middles, and crumbly muffins.

Safety and Health Questions

No one wants to swap one problem for another when avoiding gluten. MC comes from plant cellulose and doesn’t trigger gluten sensitivity or celiac reactions. Regulatory bodies like the FDA accept it as safe, and it’s been used in commercial baking for decades. Still, eating balanced, whole food-based diets matters, so relying on processed ingredients for every meal probably isn’t the healthiest practice.

How to Use MC in Your Recipes

Most gluten-free baking takes some trial and error. Start with small amounts of methylcellulose—usually 1-2% of flour weight. Mix it with dry ingredients, then add liquids. Expect dough to feel stickier than wheat-based batters. The biggest surprise hits when the bake comes out: crumb is springy, slices hold up in the toaster, and sandwiches stop falling apart in your hands. Commercially, MC shows up in many gluten-free bagels, wraps, and hamburger buns for these reasons.

Better Gluten-Free Baking: A Community Effort

Sharing recipes and swapping tips online brings better results for everyone navigating gluten-free diets. Bakers experimenting with MC often post side-by-side photos, offer advice on dosage, and share which brands give the best gelling. Food manufacturers continue to test MC with various flours—like buckwheat, teff, or potato—for better-tasting treats.

Finding What Works Best

No single ingredient fixes every problem, and MC is another tool rather than a magic wand. Still, it makes gluten-free baking more approachable. For anyone longing for homemade bread that doesn’t end up in breadcrumbs, methylcellulose opens more options at the kitchen table.

Methylcellulose MC
Names
Preferred IUPAC name Cellulose, methyl ether
Other names Methyl cellulose
Cellulose methyl ether
Methocel
E461
Pronunciation /ˌmɛθ.ɪlˈsɛl.juː.loʊs ˌɛmˈsiː/
Preferred IUPAC name Methyl cellulose
Other names Methyl cellulose
Cellulose methyl ether
MC
Methylcellulose polymer
Methocel
Pronunciation /ˌmɛθ.ɪlˈsɛl.juːˌloʊs ɛm siː/
Identifiers
CAS Number 9004-67-5
3D model (JSmol) `3D model (JSmol)` string for **Methylcellulose (MC)**: ``` CCO[C@@H]1O[C@H](CO[C@@H]2[C@H](O)[C@@H](O)[C@H](OC)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O ``` This is the SMILES string representation that can be loaded into JSmol for visualization.
Beilstein Reference 3589076
ChEBI CHEBI:64485
ChEMBL CHEMBL1201472
ChemSpider 2058105
DrugBank DB00672
ECHA InfoCard 03b17de2-bf95-478c-8bed-1c903b7c2ff7
EC Number 9004-67-5
Gmelin Reference 68263
KEGG C01739
MeSH D008742
PubChem CID 24898941
RTECS number SL6370000
UNII 42Z2K6ZN1C
UN number UN1328
CompTox Dashboard (EPA) DTXSID2020927
CAS Number 9004-67-5
Beilstein Reference 1347816
ChEBI CHEBI:64911
ChEMBL CHEMBL2084273
ChemSpider 21169704
DrugBank DB14015
ECHA InfoCard 07f4c61ec71d-46e6-aa3a-57c92d42056e
EC Number 9004-67-5
Gmelin Reference 12640
KEGG C01770
MeSH D008715
PubChem CID 24759
RTECS number SLH0458000
UNII 2Z72520VI6
UN number UN3082
Properties
Chemical formula C6H7O2(OH)3-x(OCH3)x
Molar mass 311.3 g/mol
Appearance White or off-white, odorless, tasteless, fibrous or granular powder
Odor Odorless
Density 0.5-0.7 g/cm³
Solubility in water Soluble in cold water
log P “-1.61”
Acidity (pKa) ~4.0
Basicity (pKb) 6.0 – 8.5
Magnetic susceptibility (χ) -9.6×10⁻⁶
Refractive index (nD) 1.333 to 1.335
Viscosity 4000-5000 mPa.s
Dipole moment 1.87 D
Chemical formula C6H7O2(OH)3-x(OCH3)x
Molar mass 418.458 g/mol
Appearance White or yellowish-white powder
Odor Odorless
Density 0.5 g/cm³
Solubility in water Soluble in cold water
log P -1.62
Acidity (pKa) 4.0-5.0
Basicity (pKb) 6.4
Refractive index (nD) 1.332–1.337
Viscosity 4000-5000 mPa·s
Dipole moment 1.7 D
Pharmacology
ATC code A06AC02
ATC code A06AC02
Hazards
Main hazards Not hazardous according to GHS classification.
GHS labelling GHS07
Pictograms GHS07,GHS08
Signal word Warning
Hazard statements Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Precautionary statements P264, P270, P301+P312, P330, P501
Autoignition temperature 260 °C
Explosive limits Not explosive
LD50 (median dose) LD50 (median dose): Oral, rat: > 27,000 mg/kg
PEL (Permissible) 5 mg/m³
REL (Recommended) 2%
Main hazards Not hazardous according to GHS classification.
GHS labelling GHS02, GHS07
Pictograms GHS07,GHS08
Signal word Warning
Hazard statements Not a hazardous substance or mixture according to the Globally Harmonized System (GHS)
Precautionary statements P264, P270, P301+P312, P330, P501
NFPA 704 (fire diamond) 1-1-0
Autoignition temperature 400°C
Lethal dose or concentration LD50 oral (rat) > 27,000 mg/kg
LD50 (median dose) LD50 (median dose): >5,000 mg/kg (Rat, oral)
PEL (Permissible) 10 mg/m³
REL (Recommended) 0.2-0.5%
Related compounds
Related compounds Ethylcellulose
Hydroxypropyl methylcellulose (HPMC)
Carboxymethyl cellulose (CMC)
Hydroxyethyl cellulose (HEC)
Cellulose acetate
Cellulose nitrate
Sodium carboxymethyl cellulose
Related compounds Hydroxypropyl methylcellulose (HPMC)
Carboxymethyl cellulose (CMC)
Ethylcellulose (EC)
Hydroxyethyl cellulose (HEC)
Cellulose acetate
Thermochemistry
Std molar entropy (S⦵298) 802.8 J·mol⁻¹·K⁻¹