Product Name: Mannitol
Chemical Formula: C6H14O6
CAS Number: 69-65-8
EC Number: 200-711-8
Recommended Use: Pharmaceutical excipient, sweetener, laboratory reagent, food additive
Manufacturer Name: Look for details on packaging from supplier or manufacturer
Address: Refer to official documentation for source address
Emergency Contact: Refer to country-specific poison control center phone numbers or company emergency contact
GHS Classification: Not classified as hazardous
Signal Word: None
Hazard Statements: Does not present significant health risks under normal handling
Pictograms: None required
Precautionary Statements: Do not inhale dust; avoid eye contact; use personal protective equipment as required
Potential Health Effects: Minimal irritation to eyes or skin possible if exposed
Environmental Hazards: Not expected to be hazardous to environment in small amounts
Chemical Name: D-Mannitol
Synonyms: Mannite, Manna sugar
Concentration: 99–100%
Impurities: May contain traces of other sugar alcohols but essentially pure
Ingredient CAS Number: 69-65-8
Inhalation: Move person to fresh air; seek medical advice if symptoms like coughing or difficulty breathing appear
Skin Contact: Wash skin with plenty of water and mild soap; remove contaminated clothing; consult physician if irritation develops
Eye Contact: Rinse immediately with plenty of water for at least fifteen minutes; remove contact lenses; seek medical advice if irritation persists
Ingestion: Rinse mouth; drink water; seek medical attention if adverse effects occur
Symptoms to Watch: Redness, itchiness, mild gastrointestinal discomfort possible
Suitable Extinguishing Media: Use water spray, dry chemical powder, foam, or carbon dioxide
Specific Hazards: Dust may form explosive mixtures with air if airborne particles accumulate
Protection for Firefighters: Wear self-contained breathing apparatus and protective gear
Combustion Products: Carbon monoxide, carbon dioxide
Advice for Firefighters: Approach fire from upwind; use standard fire-fighting procedures
Personal Precautions: Use dust mask, goggles, disposable gloves; avoid contact with skin and eyes
Environmental Precautions: Prevent spillage into drains and surface water
Containment Methods: Sweep or vacuum spilled material; minimize dust generation
Clean-up Methods: Collect in appropriate container for disposal; ventilate area
Advice for Emergency Responders: Wear recommended personal protective equipment
Handling: Handle with care to prevent dust formation; avoid breathing dust; use in well-ventilated area
Safe Storage Conditions: Store in tightly sealed container away from moisture or incompatible substances
Incompatible Materials: Strong oxidizers
Storage Temperature: Keep in cool, dry place, away from direct sunlight
Special Precautions: Keep containers closed when not in use; label containers adequately
Occupational Exposure Limits: No established limits for mannitol
Engineering Controls: Use local exhaust ventilation; avoid airborne dust
Hygiene Measures: Wash hands after handling; do not eat or drink in processing areas
Personal Protection: Wear safety goggles, gloves, dust mask or respirator if dust present, lab coat
Environmental Exposure Controls: Prevent large releases into environment
Appearance: White crystalline powder or granules
Odor: Odorless
Melting Point: 165-170°C
Boiling Point: Decomposes above 290°C
Solubility: Soluble in water; practically insoluble in organic solvents
pH: Approximately 5–7 (in 10% solution)
Vapor Pressure: Negligible at 20°C
Relative Density: 1.52 g/cm³
Partition Coefficient: Log Kow ≈ −3.1 (low bioaccumulation potential)
Flash Point: Not applicable
Flammability: Not easily flammable, but dust can be combustible
Chemical Stability: Stable under normal conditions
Reactivity: May react with strong oxidizing agents
Hazardous Decomposition Products: Releases carbon oxides under combustion
Polymerization: Will not occur
Conditions to Avoid: High temperature, open flame, excessive humidity
Acute Toxicity: Oral LD50 (rat): >20,000 mg/kg
Skin Irritation: Mild, not expected to cause significant irritation
Eye Irritation: Possible mild irritation from dust
Respiratory Effects: Can cause coughing or respiratory tract discomfort if dust inhaled
Long-term Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Sensitization: Not known to cause allergic reactions
Ecotoxicity: Low aquatic toxicity; not expected to harm aquatic life
Persistence and Degradability: Readily biodegradable in environment
Bioaccumulation: Low potential; does not build up in the food chain
Mobility in Soil: High water solubility, likely to move in soil
Other Adverse Effects: No known negative environmental impacts at small scale
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations
Contaminated Packaging: Rinse containers thoroughly prior to recycling or disposal
Recommended Disposal: Landfill or incineration in controlled facility when large quantities accumulate
Precautions: Prevent entry into drains or waterways in significant amounts
UN Number: Not regulated for transport
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified as hazardous
Packing Group: Not applicable
Environmental Hazards: None
Transport Precautions: Keep dry; avoid damage to packaging
TSCA: Listed in the United States Toxic Substances Control Act inventory
REACH: Complies with European chemical regulations
FDA Status: Approved for food and pharmaceutical use in many countries
GHS Classification: Not classified as a hazardous substance
Additional Regulations: Refer to country and region-specific legislation for workplace and environmental safety