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Growing up around people who worked in both agriculture and healthcare, I picked up early stories about antibiotics changing lives. Lincomycin Hydrochloride traces back to the 1960s, when researchers at Upjohn Company chanced upon a potent antibiotic produced by Streptomyces lincolnensis. In a time when penicillin resistance already cast a shadow, lincomycin felt almost miraculous for hard-to-treat Gram-positive infections. The power of this compound lay in bridging gaps, giving doctors who ran out of options something real to work with, especially among staphylococci and streptococci infections. The way this development shaped clinical and veterinary practice, particularly for cases involving penicillin or erythromycin resistance, deserves respect.
Every bottle of Lincomycin Hydrochloride sold today stands for more than a century’s grind in microbiology and synthetic chemistry. Measured in powder or injectable form, this antibiotic keeps popping up in hospitals, animal health, and research. Each vial means a promise to slow down or stop the onslaught of specific pathogens. This drug earns its shelf space because it gets straight to the ribosomal machinery of sensitive bacteria, blocking protein synthesis and giving the immune system a fighting chance. Unlike some broad-spectrum antibiotics that sweep everything in their path, lincomycin moves with focus—sticking mostly with Gram-positives and certain anaerobes. Pharmacies, clinics, and feedlots all watch their stocks because when you need it, you need it now.
I’ve watched laboratory techs describe the look and feel of pharmaceutical-grade lincomycin—it often comes as a white to off-white crystalline powder, nearly odorless, slightly bitter, and easily soluble in water. With a formula of C18H34ClN2O6S and a molecular weight just over 460, it packs a punch in a small package. In research labs, knowing things like melting point (stretching between 142°C and 150°C), pH stability, and solubility in different solvents changes how researchers approach formulation, quality control, and even storage. You don’t want a batch ruined by moisture, so desiccators and tightly sealed vials matter.
Experience taught me to check every box and bottle for more than just the name. Reputable manufacturers list the strength, usually as lincomycin hydrochloride monohydrate, with clear batch numbers and expiration dates. Impurity profiles, moisture content (often below 5%), and precise assay ranges factor into every lot. Each label doesn’t just satisfy regulators—it gives buyers confidence that they’re getting consistency and safety. Some producers add QR codes tied to their quality databases, so you can trace the journey down to the raw materials and final test results.
From watching fermentation tanks to running chromatography columns, I know there’s nothing easy about prepping pharmaceutical-grade lincomycin. Most processes start with deep-tank fermentation, where Streptomyces lincolnensis churns out raw antibiotic in a careful balance of nutrients, pH, and temperature. Extracting the crude product from the culture broth requires solvent extraction and multiple purification steps, cutting out byproducts and concentrating the active ingredient. Crystallization multiple times weeds out impurities, followed by reconstitution in hydrochloric acid to stabilize the compound. Workers know contamination, temperature spikes, or even small variances in timing can wreck months of work.
Chemists in research settings never leave well enough alone, and lincomycin is an open door for exploring structure-activity relationships. Simple modifications, like swapping an N-methyl group or esterifying the 7-hydroxy position, led to derivatives like clindamycin—arguably more effective and widely used now than lincomycin itself. Halogenation, amidation, and even carbamate formation have shaped how these antibiotics work, especially in terms of tissue penetration and activity spectrum. Many postgraduate students run these reactions, looking for hints of better absorption, less toxicity, or a broader kill range. Sometimes, tiny tweaks make the difference between a medicine that barely works and one that’s a frontline agent.
In hospital pharmacies, veterinary supply catalogs, and academic papers, lincomycin hydrochloride often goes by alternative names. Chemically, you’ll see it as 7(S)-Chloro-6,8,9,10,11,12-hexahydro-11-hydroxy-6-methyl-8-[[4-methyl-2-(propan-2-yl)pyrrolidin-1-yl]carbonyl]-1-oxa-4-thia-11-azacyclotridec-2-ene-2-carboxamide hydrochloride. In trade, it pops up as L-Mycin, Lincocin, or Linco-Spectin when mixed with spectinomycin for animal use. Relying on synonyms sometimes leads to confusion on purchase orders; manufacturers and regulators push for standardized labeling to cut down on dosing errors and counterfeiting.
As someone who’s sat through plenty of lab safety meetings, I’ve seen firsthand why strong safety protocols matter with lincomycin. Handling the raw powder or solutions calls for gloves and protective eyewear, and any spills have to hit a disinfectant right away. Each facility keeps Material Safety Data Sheets on hand, reviewing possible reactions, accidental exposure pathways, and decontamination steps. On the clinical side, allergic reactions—ranging from rashes to severe anaphylaxis—get flagged in patient charts, and medics watch for signs of colitis. Occupational exposure isn’t some abstract hazard either; inhalation or skin contact can trigger symptoms after hours or days. Training staff, using closed systems when possible, and running regular audits cuts down on accidents. Reports suggest rare—but real—issues with overuse and environmental persistence, making the conversation about antibiotic stewardship more urgent each year.
Lincomycin hydrochloride serves humans and animals alike. It’s still a first-line agent for certain MRSA skin infections, bone and joint infections, and in settings where penicillin allergy blocks other choices. Veterinarians reach for it when livestock develop swine dysentery, necrotic enteritis in poultry, or joint infections resistant to standard drugs. Even aquaculture gets a boost from this antibiotic, as it curbs some waterborne bacterial pathogens and keeps fish stocks healthy. Agricultural use draws the most heated debates about resistance, but farmers argue that sick herds without access to effective antibiotics pose worse risks. In practice, the drug carves out a clear spot: it handles jobs where nothing else will, so long as doses and duration get managed carefully.
Working alongside academic teams, I’ve seen how research projects pit lincomycin as both a model compound and a candidate for improved analogs. Laboratory screens test new derivatives for activity against MDR (multi-drug resistant) strains. Researchers dive into mechanisms behind resistance, focusing on methylation of 23S rRNA or efflux pump mutations. Some teams hunt for ways to extend the drug’s half-life or reduce gut flora disruption. Funding often comes with strings attached: show reduced side effects, demonstrate better selectivity, or cut costs on large-scale synthesis. Partnerships with biotech firms can lead to surprising results—novel formulations, smarter combinations with beta-lactamase inhibitors, or even prodrugs designed for slow release. Real storytelling, backed by open data, drives grant decisions and keeps the pace up.
Nobody in the health science field shrugs off toxicity concerns, and lincomycin gets its share of scrutiny. The major risks always center around gastrointestinal upset, particularly antibiotic-associated colitis caused by Clostridioides difficile overgrowth. Long-standing reviews point to hepatic and renal function monitoring for patients on prolonged therapy, especially those already on other drugs. Animal toxicity studies show predictable patterns: at high doses, rats and dogs display weight loss, diarrhea, and changes in liver enzymes. In human cases, hypersensitivity and cross-reactivity with other lincosamides can spring up unexpectedly, underscoring the need for good pre-screening and patient education. Resistance genes, like erm, now get tracked in stool and soil samples in communities with heavy lincomycin use, since they can flow from animals to humans via food and water. Regulators push for more data-sharing across borders, so that global patterns of toxicity and resistance shape policy, not just sales numbers.
The clock won’t stop on antibiotic resistance, and every class—lincosamides included—feels the pinch. As a working writer who talks often to clinicians, I hear about the challenge of preserving drug efficacy through stewardship and innovation. New ways of pairing lincomycin with other antibiotics, including old favorites like doxycycline or gentamicin, offer some hope. Drug developers tinker with nano-formulations to improve tissue targeting and reduce off-target effects. On the agricultural side, big promises get made about “alternatives” to antibiotics, but so far, basic antibiotics like lincomycin still hold the line against outbreaks. Future breakthroughs probably hang on better diagnostics, more targeted drug delivery systems, and policies that balance patient care with antibiotic preservation for future generations. The story of lincomycin isn’t fading—it keeps evolving, pushed forward by science, necessity, and the harsh realities of both human and animal health.
Lincomycin Hydrochloride comes from a type of soil-dwelling bacteria, and it grabbed attention years ago for its ability to fight infections in both animals and humans. This compound knocks down a range of bacteria, especially gram-positive types. When doctors or veterinarians feel stuck with an infection that does not respond to penicillin or erythromycin, lincomycin steps up as an alternative.
Pneumonia, skin infections, bone infections, and blood infections can upend lives. The bacteria responsible for these diseases sometimes laugh off common antibiotics. That’s where lincomycin hydrochloride brings hope. In my own home, I’ve seen neighbors’ livestock bounce back from foot rot after standard medicines failed. Veterinarians often reach for lincomycin to treat pigs, cattle, or poultry facing respiratory or joint infections. The results often speak for themselves; herds recover, and farm families avoid massive financial blows.
Some bacteria develop a serious resistance to the drugs we once trusted. Each year, experts warn about antibiotic resistance reshaping the future of medicine and food production. Lincomycin holds a vital place as a trusty backup. Doctors reach for it in bone infections, complicated wounds, and dental issues when first-line antibiotics can’t clear the bacteria. It gets prescribed in situations where allergies or previous bad reactions make other drugs off limits. Lincomycin can get injected, swallowed as a capsule, or mixed into feed for animals.
This medicine doesn’t fix everything. Some bacteria ignore it, and using it when not truly needed only adds to resistance problems. Side effects include digestive upset, and in people with severe kidney or liver issues, it complicates things. There’s a risk of a dangerous colon infection called C. difficile, especially in hospitals or nursing homes. So, doctors aim for careful use and clear need.
Health experts keep raising the alarm about superbugs—bacteria that no longer respond to what we have on the shelf. Wasting antibiotics on viruses or minor aches drives this trend. Vets and doctors are under pressure to rethink old habits, turning to options like lincomycin only after confirming a bacterial problem. Rapid tests and smarter diagnostic tools help guide decisions. In my days volunteering at a rural clinic, having a culture test to spot the real bacteria made a world of difference. Farms tracking every dose and following withdrawal times for animal products reduce risks for everyone.
Lincomycin hydrochloride matters because it fills gaps left when other medicines fail. Still, its success story depends on careful, evidence-based use. That means listening to the advice of professionals trained in infectious diseases, using lab tests when possible, and making sure prescriptions match real need—not just routine or convenience. If people stay mindful of the risks and benefits, lincomycin and antibiotics like it will keep bringing relief long into the future.
Lincomycin Hydrochloride usually steps in when stubborn bacterial infections don’t budge against regular antibiotics. It’s especially useful in fighting severe infections caused by certain bacteria. Yet with this power comes the risk of some side effects. Recognizing those dangers and knowing what they mean can spark better conversations with doctors and help people avoid unnecessary worry or harm.
Most people expect a few bumps along the road with any antibiotic. Lincomycin’s most frequent offenders? Upset stomach, nausea, vomiting, or loose stools. These reactions rarely last long and often fade as the body adjusts. Sometimes appetite dips during treatment, but staying hydrated and eating lighter meals tends to help.
Using lincomycin on an empty stomach can make some of these problems more noticeable. Personal stories back this up: friends on antibiotics for dental infections have mentioned short-lived queasiness but bounced back quickly after taking doses with food.
Every medication can cause more than mild trouble. A deeper issue with lincomycin involves gut bacteria. The antibiotic wipes out both good and bad bacteria, giving a nasty bug called Clostridioides difficile a chance to take over. This infection brings heavy diarrhea, fever, and abdominal pain. Hospital infection teams recognize this so well that they automatically look out for it when someone complains about stomach pain during or after antibiotic courses.
Allergic reactions, though rare, can unfold quickly—rashes, swelling, or trouble breathing. As someone with a family history of penicillin allergies, I’ve seen relatives need urgent care when hives and throat tightness kicked in. It's wise to never ignore even what looks like a harmless rash.
Lincomycin sometimes irritates the liver or causes shifts in blood counts. Signs like yellowing skin, dark urine, or unexplained bruising shouldn’t get brushed aside. Anyone who’s faced previous liver or kidney trouble should be upfront with their doctor before starting this drug.
Routine blood work during longer treatment spells helps spot problems early. One community pharmacist tells patients about blood checks simply because catching an issue early beats waiting until symptoms spiral.
A lot of folks juggle more than one prescription. Lincomycin can pick fights with muscle relaxants or certain heart pills. Mixing these drugs sometimes leads to muscle weakness or irregular heart rhythms. Explaining every medication, vitamin, or herbal remedy you use during doctor visits gives better odds of avoiding a bad mix.
Good communication matters most. Any new rash, ongoing diarrhea, odd muscle weakness, or unexpected bruising should prompt a fast call to your healthcare team. Honest reporting helps providers adjust doses or switch drugs if needed. Pharmacies also serve as a good resource—many now provide medication reviews that spotlight risky combinations.
Education plays a key role. A simple printed handout explaining warning signs, along with advice to finish the full course unless told otherwise, helps most people stay safe. Depending on how you feel, don’t hesitate to push back and ask questions.
No one wants to fear their medicine. Lincomycin Hydrochloride offers vital help for hard-to-treat infections, but it brings certain risks. Honest discussions, alertness for side effects, and open access to medical help let people use it wisely without unnecessary setback. Knowledge, paired with accessible care, lets people handle side effects confidently and get the best out of treatment.
Lincomycin Hydrochloride treats serious bacterial infections. Often, you find it used for people who can’t take penicillins or when other antibiotics won’t work. Every person doesn’t get the same dose because things like age, weight, and how sick they are make a difference. One thing stays true: this isn’t a medicine for colds or viral ailments, and using it that way probably causes more harm than good.
The drug comes as an injectable form or as capsules, but for really tough infections, doctors prefer intravenous or intramuscular shots. People usually start with about 600 mg to 1 gram injected every 8 to 12 hours. Doses jump higher for life-threatening infections because getting the infection under control fast matters even more. Pediatricians use weight to set doses, not one-size-fits-all numbers. By paying attention to these details, doctors protect people from under-treatment and over-exposure to the drug.
Every patient reacts differently. Kidney or liver problems change how long the drug stays in the body. Physicians usually monitor kidney and liver functions and lower the dose as needed. Regular checks on drug levels make sense, especially for folks on long-term treatment.
Giving too little won’t clear the infection. Giving too much leads to diarrhea, colitis, or allergic reactions. Some patients get serious side effects, including a form of colitis linked to Clostridioides difficile. The FDA says people and doctors need to watch closely for watery stool, cramps, and fever. In this area, I’ve seen patients ignore warning signs—sometimes the outcome can be devastating. Open conversation between doctor and patient goes a long way in preventing these problems.
Doctors should double-check what medicines and supplements people take before starting Lincomycin Hydrochloride. Drug interactions with muscle relaxants make surgery riskier and can increase sedative effects. Nurses and pharmacists play a direct role here, catching issues before anyone gets hurt.
Educating patients upfront beats chasing problems later. People do better when they know why sticking to the schedule matters, so practitioners should explain timing in terms patients actually use: “Eight in the morning, four in the afternoon,” not, “every eight hours.” Pills and shots—especially if given at a pharmacy or clinic—should be documented and checked for accuracy. I’ve watched people fall through the cracks just because no one explained side effects or checked how easily they could follow instructions at home.
The CDC and World Health Organization urge everyone to stop overusing antibiotics. Lincomycin Hydrochloride stands as a last-line option in many clinics, so responsible use isn’t just best practice—it protects whole communities from resistant bacteria. If anyone feels unwell after starting the medicine, fast reporting to the medical team saves lives. Everyone from the doctor’s office to the family at home has a job to play here.
Many hospitals now use electronic reminders and double-check systems to make sure the right person gets the right dose at the right time. Better communication and more practical education could cut down on unnecessary risks. Doctors can lean on infection disease experts and pharmacists when things get complicated. For families, learning to recognize warning signs of side effects should come with every prescription. In the end, success depends on focus, teamwork, and respect for the drug’s power to heal or harm.
Doctors started using lincomycin hydrochloride decades ago to fight certain bacterial infections. Sometimes, old medicines stay relevant because they work against bugs that laugh in the face of newer drugs. Before reaching for this antibiotic, it makes sense to dig into who should steer clear and what kind of issues patients and providers commonly run up against. Lives and health both depend on good choices.
Allergies to lincomycin or clindamycin deserve real attention. Those with a known reaction to these drugs have landed in emergency rooms with rashes, throat swelling, and trouble breathing. No one needs that kind of risk. The body can remember an allergy even if it happened years ago, so anyone with a history of problems from “lincosamide” antibiotics needs another option. Skipping a thorough medical history can mean danger, plain and simple.
Lincomycin clears out through the liver and kidneys. Those with weak liver or kidney function might end up with more of the drug floating around in their bodies than doctors planned. This can turn a standard dose into a toxic one. Blood tests tell the story—folks with cirrhosis or struggling kidneys often need a different drug, or at least a different dose, plus careful monitoring from their providers. Ignoring these warning signs can lead to hearing loss, nerve issues, or even more severe reactions.
People hear “antibiotic,” but not everyone knows about the fallout: diarrhea, sometimes extreme. Lincomycin can wipe out friendly gut bacteria, opening the door for Clostridioides difficile infection. This gut bug causes everything from mild stomach cramping to life-threatening colitis. Studies peg lincomycin, like its cousin clindamycin, among the usual suspects in hospital-acquired C. diff outbreaks. Patients with a history of C. diff, the elderly, and those on other antibiotics deserve special caution.
Research on lincomycin during pregnancy remains thin. Some animal studies suggest possible risks, and without better data, doctors wrestle with the balance of benefit versus harm. The FDA places this drug in a category where benefits must justify risks. Mothers who breastfeed can pass small amounts of lincomycin through their milk; the impact on babies is not fully mapped out. Babies under a month old or premature infants may process this drug poorly, and most doctors prefer a different choice for the smallest patients.
Patients who take muscle relaxants might run into problems. Lincomycin can boost the effect of neuromuscular blockers, used during surgery or in critical care, sometimes leading to dangerous breathing issues. Letting the care team know about all ongoing medications helps dodge interactions. Checking supplement labels for undisclosed sources of similar compounds also matters.
Old medicines bring real value, especially as resistance to antibiotics rises. Using lincomycin demands solid patient-doctor communication. Checking medication lists, reviewing health history, and reporting every odd symptom right away can mean the difference between trouble and safe recovery. Only experience, careful review, and patient honesty come close to replacing a crystal ball in modern medicine. Doing the work up front gives everyone the best shot at success.
Lincomycin Hydrochloride works as an antibiotic, usually for serious infections triggered by bacteria that ignore other medication. Most folks only get prescribed this drug after more common options drop out—resistance or allergies sometimes leave few choices. It’s one of those medicines your healthcare provider doesn’t reach for right away.
Mixing prescription drugs together usually worries people for a good reason. Two medicines can mess with each other’s job, canceling out benefits or stirring up unexpected trouble. When I had to take antibiotics for an infection after surgery, my pharmacist peppered me with questions about what else I took—there’s a reason for that attention. Every added pill in the mix estimates new risks.
Lincomycin Hydrochloride brings its own risks for people who use other medications. For example, this drug doesn’t blend well with common muscle relaxants, because it can boost the effects and raise the chance for muscle weakness. Patients who already need support for breathing—those in intensive care, for instance—can land in real trouble if the mix dulls muscle action even more.
Mixing lincomycin with other antibiotics probably seems routine. Doctors often use multi-drug approaches for tricky infections. But some antibiotics clash, making each other less effective or harder on the body’s systems. Taking lincomycin and erythromycin together blocks the effect of both, instead of improving it.
Some families of medication can stress organs further if mixed. Lincomycin Hydrochloride leaves the body through the liver and kidneys. Medicines you already take for high blood pressure, diabetes, or seizures might grind down those organs too. Tossing in lincomycin can nudge someone closer to harm.
Most folks don’t think about gut bacteria until antibiotics shake things up. Lincomycin sometimes causes diarrhea or more serious gut infections like C. difficile. If you’re already taking other drugs that trigger diarrhea, or if you have bowel issues—say, colitis—the risks pile on.
Doctors have watched this happen over and over. Trouble can grow fast, so most try to plan ahead by reviewing the full list of daily meds before starting lincomycin.
People can feel overwhelmed looking at a big list of medications on a printout from the pharmacy. Organizing your meds with a health professional can make a real difference. A medicine review with a pharmacist or doctor uncovers clashes before they cause harm. They don’t just tick off generic names—they figure out what works with what, based on your body and your situation. If you’re prescribed lincomycin and you’re already on a few prescriptions, don’t just add it to your daily pillbox.
Detailed communication solves a lot of problems before they start. Always give your provider the plain truth about what you already take, including over-the-counter medicines or even herbal supplements. When pharmacies or clinics know the whole story, they catch problems fast.
Some hospitals and clinics now use electronic systems to flag risky combinations. These tools catch many problems, but they cannot replace a patient’s awareness or willingness to speak up. If something seems off, it pays to ask before signing off on new antibiotic therapy or any new medication.
| Names | |
| Preferred IUPAC name | (2S,4R)-N-[(1S,2S)-1-Methyl-4-propyl-L-prolyl]thiomorpholine-4-carboxamide hydrochloride |
| Other names |
Lincocin Lincomycin HCl Lincomycin hydrochloride monohydrate |
| Pronunciation | /lɪnˈkəʊmɪsɪn haɪdrəˈklɔːraɪd/ |
| Preferred IUPAC name | (2S,4R)-N-[(1S,2R)-1-Methyl-4-propylpyrrolidin-2-yl]-N-methyl-6,8-dideoxy-6-(methylthio)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride |
| Other names |
Lincocin Mycivin Mitramycin Lincomycin HCl |
| Pronunciation | /lɪnˈkəʊmɪsɪn haɪdrəˈklɔːraɪd/ |
| Identifiers | |
| CAS Number | 859-18-7 |
| Beilstein Reference | 1561695 |
| ChEBI | CHEBI:64627 |
| ChEMBL | CHEMBL1094 |
| ChemSpider | 141184 |
| DrugBank | DB01627 |
| ECHA InfoCard | 03d1fbe3-c3d4-4997-a593-2b17bf7e4256 |
| EC Number | 297-880-5 |
| Gmelin Reference | 82993 |
| KEGG | D00945 |
| MeSH | D008218 |
| PubChem CID | 3000468 |
| RTECS number | OP0450000 |
| UNII | 6HX7RDT26Z |
| UN number | UN3249 |
| CAS Number | 85664-99-1 |
| 3D model (JSmol) | `/data/lincomycin_hydrochloride/cid_3000348.jmol` |
| Beilstein Reference | 1364156 |
| ChEBI | CHEBI:64371 |
| ChEMBL | CHEMBL1621 |
| ChemSpider | 21305686 |
| DrugBank | DB01627 |
| ECHA InfoCard | 100.111.613 |
| EC Number | 296-657-5 |
| Gmelin Reference | 1205958 |
| KEGG | D08167 |
| MeSH | D008213 |
| PubChem CID | 3000178 |
| RTECS number | OV965M9368 |
| UNII | 66H00G217A |
| UN number | UN2811 |
| Properties | |
| Chemical formula | C18H34ClN2O6S |
| Molar mass | 407.96 g/mol |
| Appearance | White or almost white crystalline powder |
| Odor | Odorless |
| Density | 1.37 g/cm3 |
| Solubility in water | Very soluble in water |
| log P | -1.6 |
| Acidity (pKa) | 12.6 |
| Basicity (pKb) | pKb: 7.6 |
| Magnetic susceptibility (χ) | -87.0 × 10⁻⁶ cm³/mol |
| Dipole moment | 4.92 D |
| Chemical formula | C18H35ClN2O6S |
| Molar mass | 407.96 g/mol |
| Appearance | White or almost white crystalline powder |
| Odor | Odorless |
| Density | 1.3 g/cm³ |
| Solubility in water | Freely soluble in water |
| log P | -1.6 |
| Acidity (pKa) | 6.9 |
| Basicity (pKb) | 7.6 |
| Magnetic susceptibility (χ) | -73.0e-6 cm³/mol |
| Refractive index (nD) | 1.64 |
| Dipole moment | 4.98 D |
| Pharmacology | |
| ATC code | J01FF02 |
| ATC code | J01FF02 |
| Hazards | |
| Main hazards | Harmful if swallowed. Causes serious eye irritation. May cause an allergic skin reaction. |
| GHS labelling | GHS07; GHS08; Warning; H302, H312, H332, H373 |
| Pictograms | GHS05,GHS07 |
| Signal word | Warning |
| Hazard statements | Hazard statements: Harmful if swallowed. Causes serious eye irritation. May cause respiratory irritation. |
| Precautionary statements | P264, P270, P273, P280, P301+P312, P305+P351+P338, P308+P313, P337+P313 |
| Lethal dose or concentration | LD₅₀ (oral, rat): 1260 mg/kg |
| LD50 (median dose) | LD50 (median dose): Oral-rat LD50: 2450 mg/kg |
| PEL (Permissible) | PEL: 5 mg/m³ |
| REL (Recommended) | 600 mg daily |
| Main hazards | May cause an allergic skin reaction; causes serious eye irritation. |
| GHS labelling | GHS07, GHS08 |
| Pictograms | GHS05,GHS07 |
| Signal word | Warning |
| Hazard statements | Hazard statements: "H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary statements | Wash thoroughly after handling. Do not eat, drink or smoke when using this product. |
| Lethal dose or concentration | LD50 oral rat 1300 mg/kg |
| LD50 (median dose) | LD50 (median dose): Mouse oral LD50 = 1300 mg/kg |
| NIOSH | Not listed |
| PEL (Permissible) | PEL: Not established |
| REL (Recommended) | 600 mg |
| Related compounds | |
| Related compounds |
Clindamycin Lincomycin Pirilimycin Celesticetin |
| Related compounds |
Clindamycin Lincomycin Pirlimycin Clindamycin phosphate Clindamycin hydrochloride |
