Product Name: Lactoferrin
Synonyms: Lactotransferrin
CAS Number: 146897-68-9
Recommended Use: Research, dietary supplement, food additive
Supplier Details: Manufacturer’s address, telephone, emergency contact
Product Type: Protein compound derived from milk
Molecular Formula: C1413H2244N388O394S8
Molecular Weight: Approximately 80,000 Da
Appearance: White to pale pink powder, no noticeable odor
GHS Classification: Not classified as hazardous
Acute Health Effects: Dust may cause mild eyes, skin or respiratory irritation in sensitive individuals
Chronic Health Effects: No evidence for chronic toxicity in normal use
Inhalation: Prolonged inhalation may cause coughing or discomfort
Skin Contact: Repeated exposure can dry or irritate skin
Eye Contact: Dust particles irritate eyes
Ingestion: Low risk; no harmful effects expected at normal exposure
Hazard Statements: Slight irritant in powder form
Precautionary Statements: Use appropriate PPE to minimize exposure
Main Ingredient: Lactoferrin, >95% purity
Impurities: Trace lactose, casein, salts (sodium, calcium)
Source: Purified from bovine or recombinant sources
Additives: None typically used
Allergens: Contains milk protein
Regulatory Standard: Food-grade or pharmaceutical-grade, depending on intended use
Inhalation: Move person to fresh air, seek medical help if discomfort continues
Skin Contact: Wash area with soap and water; remove contaminated clothing
Eye Contact: Rinse carefully with plenty of clean water for several minutes; remove contact lenses if present
Ingestion: Rinse mouth, drink water to dilute; no specific treatment necessary unless symptoms persist
Note to Doctors: Treat symptomatically, supportive care only
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Fire Hazards: Airborne dust may form explosive mixture; not highly flammable
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and protective clothing
Special Precautions: Evacuate area, avoid breathing dust and fumes, keep containers cool
Personal Precautions: Wear dust mask, gloves, goggles
Environmental Precautions: Prevent large spills reaching watercourses, drains or soil
Clean-Up Methods: Carefully scoop or sweep up to minimize dust, collect in suitable, labeled containers
Waste Disposal: Dispose according to national and local regulations
Decontamination: Wash spill area with water, ventilate well
Handling: Avoid raising dust, use local exhaust ventilation, wear suitable PPE
Storage Conditions: Keep container tightly closed, store in a cool, dry, well-ventilated place
Temperature Sensitivity: Stable under recommended storage, avoid heat and direct sunlight
Packaging Material: Use food-grade, airtight containers
Incompatibilities: Avoid exposure to strong acids, oxidizers, or moisture
Engineering Controls: Local exhaust ventilation or general room ventilation
Exposure Limits: No established occupational exposure limits for lactoferrin
Personal Protection:
— Eye/Face Protection: Safety goggles
— Skin Protection: Laboratory gloves, protective clothing
— Respiratory Protection: Particle filter mask if dust generation possible
Hygiene Measures: Wash hands thoroughly, remove contaminated clothes
Environmental Precautions: Prevent release to drains, control dust
Form: Powder
Color: White to light pink
Odor: Slight, proteinous
pH (1% solution): 6.0–7.5
Melting Point/Freezing Point: Not available – denatures above 70°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water
Partition Coefficient: Not available
Vapor Pressure: Negligible
Evaporation Rate: Not applicable
Flammability: Slight risk with dust
Bulk Density: 0.2–0.6 g/cm³
Stability: Stable under normal conditions
Chemical Stability: Stable under recommended handling and storage
Reactivity: Low reactivity; avoid exposure to strong oxidizers or acids
Conditions to Avoid: High temperature, high humidity, direct sunlight
Materials to Avoid: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Oxides of carbon and nitrogen
Polymerization: Does not occur
Acute Toxicity: No data for LD50; animal studies show low toxicity
Oral Exposure: Common in infant formula and supplements – widely considered safe
Dermal Exposure: Mild irritation possible with prolonged contact
Inhalation Exposure: Dust may cause mild cough or throat discomfort
Chronic Exposure: No evidence for carcinogenicity, teratogenicity, reproductive, or mutagenic effects
Allergenicity: Contains milk protein, may cause reactions in sensitive individuals
Other Health Effects: No known adverse effects with normal use; excessive exposure to dust should be limited
Ecotoxicity: Low environmental hazard based on protein structure and biodegradability
Persistence/Degradability: Readily biodegradable by soil and aquatic microbes
Bioaccumulation: Not expected to bioaccumulate
Mobility in Soil: Expected to bind or degrade rapidly
Aquatic Toxicity: No adverse effects reported
Other Information: Biologically derived, breaks down in environment without persistent residues
Waste Disposal Methods: Dispose of as non-hazardous organic waste in accordance with local, regional, national regulations
Contaminated Packaging: Rinse thoroughly before reuse or recycling
Special Precautions: Minimize dust during disposal, avoid uncontrolled discharge to water or soil
Recommendation: Use licensed professional waste disposal contractor
UN Number: Not regulated
UN Shipping Name: Not classified as dangerous goods
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: None
Special Precautions for User: Protect from humidity, handle sealed and labeled containers
Transport in Bulk: Not applicable to protein powders
International Laws: Not classified as hazardous by GHS, OSHA, or EU CLP
US Regulations: FDA: Generally Recognized as Safe (GRAS) for certain uses
EU Regulations: Included in Novel Foods catalog, permitted in food supplements
Canada Regulations: Listed as food ingredient and supplement
Other Country Rules: Check local requirements for food or supplement use
Labeling Requirements: Ingredient name, allergen warning, batch number, expiration date, manufacturer info
Workplace Hazard Statements: Occupational hazards low, align with good laboratory practices