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Lactobacillus plantarum Material Safety Data Sheet

Identification

Product Name: Lactobacillus plantarum
Synonyms: L. plantarum
Recommended Uses: Probiotic preparation, food supplement, industrial fermentations
Supplier Details: Name, address, and emergency contact number of the supplier
CAS Number: 27321-97-1
Product Type: Bacterial culture, living organism
Molecular Formula: Not applicable for whole organism
Relevant Identified Uses: Food production, scientific research, food preservation, dietary supplements, fermentation processes

Hazard Identification

Classification: Not classified as hazardous according to Regulation (EC) No. 1272/2008 or OSHA HCS
Physical Hazards: Non-flammable powder or liquid, does not support combustion
Health Hazards: Not known to cause infections in healthy individuals; immunocompromised groups could be at risk if ingested in large amounts
Environmental Hazards: Expected to have minimal environmental impact, as L. plantarum is naturally occurring
Label Elements: No signal word, hazard pictogram, or hazard statement required
Potential Adverse Effects: Allergic reactions rarely reported in sensitive populations; mild gastrointestinal discomfort possible
Precautionary Statements: Avoid inhalation of dusts and aerosols; wash hands after handling cultures

Composition / Information on Ingredients

Cultured Ingredient: Lactobacillus plantarum (viable cells, typically lyophilized)
Concentration: Purity typically exceeds 95% of viable L. plantarum cells per gram
Carrier/Substrate: May include maltodextrin, whey powder, or skim milk as stabilizers, percentage varying by product
Impurities: Unlikely to present hazardous contaminants when sourced from certified manufacturers
Nature of Mixture: Bacterial cell culture with inert carrier (if present), no toxic components identified
CAS Number: 27321-97-1 for L. plantarum specifically
Other Components: Minor amounts of water, residual growth media traces, pH buffering agents in some preparations

First Aid Measures

General Advice: Move affected person away from exposure if inhaled; seek medical attention for persistent symptoms
Inhalation: Move to fresh air; rinse mouth with water if respiratory irritation occurs
Skin Contact: Wash with soap and water; remove contaminated clothing; seek medical attention if irritation persists
Eye Contact: Rinse eyes with plenty of clean water for several minutes; remove contact lenses if possible; get medical help for persistent redness or discomfort
Ingestion: Rinse mouth, drink water; L. plantarum is not toxic when consumed as food, but large doses may trigger mild gastrointestinal upset in sensitive individuals
Notes to Physician: Treat symptomatically; report any unexpected reactions or suspected allergic responses

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Special Hazards Arising: Product is unlikely to burn, but organic carrier materials could release smoke or fumes
Protective Equipment: Firefighters should wear suitable protective gear for surrounding fire
Advice for Firefighters: Avoid inhalation of dust, decomposition products, and smoke
Combustion Products: Burning may produce CO, CO2, nitrogen oxides when mixed with organic carriers
Other Considerations: L. plantarum does not support combustion and does not contribute significantly to fire load

Accidental Release Measures

Spill Response: Collect material carefully to avoid dust formation; sweep up and place in a suitable container
Personal Precautions: Use protective gloves and safety goggles; avoid breathing dust or aerosols
Environmental Precautions: Prevent release into surface water, drains, or soil in large quantities
Cleanup Procedures: Wash contaminated area with water and detergent
Disposal Method: Discard as non-hazardous biological waste in compliance with local regulations
Emergency Procedures: In case of large spills, ventilate area and notify responsible personnel

Handling and Storage

Handling: Wear appropriate protective clothing; avoid creating dust or aerosols; minimize handling to reduce risk of exposure
Hygiene Measures: Wash hands before eating, drinking, or smoking; keep work area clean
Safe Storage: Store in original packaging, tightly closed, and in a cool, dry environment
Temperature Recommendations: Refrigerate or freeze for long-term storage to preserve viability; avoid heat and direct sunlight
Packaging Materials: Use food-grade or laboratory-grade containers; avoid moisture ingress
Incompatibilities: Avoid contact with strong oxidizers or acids
Special Considerations: Follow local regulations for storage of live microbial cultures

Exposure Controls and Personal Protection

Engineering Controls: Use with local exhaust ventilation or in a biosafety cabinet for laboratory work
Personal Protective Equipment: Gloves, lab coat, protective goggles
Respiratory Protection: Use approved particulate respirators if dust or aerosol generation is likely
Hand Protection: Disposable gloves recommended during direct handling
Eye Protection: Chemical splash goggles or safety glasses
Skin Protection: Protective clothing suitable for biological work
Exposure Limits: Not established for this organism; natural exposure common through fermented food products

Physical and Chemical Properties

Appearance: Off-white to tan, fine powder or lyophilized pellet; may also be supplied as a liquid suspension
Odor: Faintly sour or fermented aroma
pH: Typically neutral to slightly acidic in suspension (pH 5.5–7.5)
Boiling Point/Range: Not relevant for solids
Melting Point/Range: Not applicable
Solubility: Dispersible in water
Flammability: Product does not ignite easily; organic carriers may support combustion at high temperatures
Density: Variable, product dependent
Stability: Stable under normal temperatures and recommended storage conditions
Partition Coefficient: Not applicable
Vapor Pressure: Not applicable

Stability and Reactivity

Chemical Stability: Remains stable when stored as recommended
Reactivity: Not known to react dangerously with other substances
Hazardous Reactions: No hazardous polymerization or decomposition under normal conditions
Conditions to Avoid: Excessive heat, moisture, or direct sunlight may reduce organism viability
Incompatible Materials: Strong acids, bases, and oxidizing agents
Hazardous Decomposition Products: Degradation under fire yields CO, CO2, and undeclared organics from carrier material
Shelf Life: 1–2 years at recommended storage conditions

Toxicological Information

Acute Toxicity: Studies in animals and humans show no evidence of toxicity in prescribed use
Chronic Toxicity: No long-term effects identified from ingestion; safety confirmed through centuries of food use
Inhalation: Large volumes could irritate respiratory tract, particularly with underlying sensitivity
Skin Contact: Not a known skin sensitizer
Eye Contact: Mechanical irritation only, no significant toxicity
Ingestion: Safe for general public in food uses; possible discomfort with intentional massive overdose
Sensitization: Rare allergic responses possible in atopic individuals
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No evidence for carcinogenic, genotoxic, or teratogenic effects

Ecological Information

Ecotoxicity: Low risk to aquatic and terrestrial life; natural component of many ecosystems
Persistence and Degradability: Organism does not persist in open environments
Bioaccumulation Potential: Not expected to accumulate in biota
Mobility in Soil: Limited, owing to biological degradation and environmental controls
Other Effects: Introduced strains unlikely to upset existing microbial balance at intended levels
Wastewater Treatment: Readily removed by sanitary treatment processes
Regulatory Listings: Not listed as harmful to the environment by major regulatory agencies

Disposal Considerations

Product Disposal: Treat as non-hazardous biological waste; inactivate by autoclaving if disposal regulations require
Packaging Disposal: Non-contaminated packaging can be disposed as regular waste, following local recycling requirements
Methods: Incinerate or landfill according to local, regional, and national guidelines
Hazardous Waste Status: Not considered hazardous by biodegradable waste standards
Special Instructions: Avoid release into unregulated environments; prevent bulk quantities from entering water systems

Transport Information

UN Number: Not classified as a hazardous material for transportation
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not subject to transport restrictions
Packing Group: Not regulated
Marine Pollutant: Not applicable
Special Precautions: Protect package from moisture and rough handling
Mode of Transport: Safe by air, land, and sea; no special precautions needed
Regulatory Compliance: Complies with IATA, IMDG, ADR, and DOT rules for non-hazardous goods

Regulatory Information

Safety, Health, and Environmental Regulations: Product meets the conditions for Generally Recognized As Safe (GRAS) under US FDA; listed in the European Food Safety Authority (EFSA) Qualified Presumption of Safety (QPS)
Labeling for Microbial Products: Not subject to hazard labeling for transportation or workplace safety
Allergen Statements: Carrier ingredients may require allergen disclosure, such as dairy-based fillers
Worker Protection: No exposure limits set by OSHA or ACGIH
Inventory Listings: Included in national inventories for substances allowed in food applications
Import/Export Control: No special restrictions identified
GMO Status: Non-GMO unless declared otherwise by the supplier