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Material Safety Data Sheet: Lactobacillus paracasei

Identification

Product Name: Lactobacillus paracasei
Synonyms: L. paracasei, Probiotic bacterial culture
Recommended Uses: Probiotic supplements, food fermentation, animal feed additives
Manufacturer Contact: Refer to supplied product documentation for producer details
Emergency Phone Number: Listed in manufacturer section of packaging
Chemical Family: Lactic acid bacteria

Hazard Identification

GHS Classification: Not classified as hazardous under most regulatory frameworks
Label Elements: No signal word or hazard symbol required
Potential Health Effects: Generally regarded as safe in intended uses; may cause mild irritation to sensitive individuals on skin or eye contact; inhalation of powder can cause respiratory discomfort
Precautionary Statements: Prevent formation of dust and contact with open wounds or eyes
Other Hazards: Individuals with compromised immune systems should avoid direct exposure to large quantities

Composition / Information on Ingredients

Component: Lactobacillus paracasei
Concentration: Pure or blended culture, percentage provided on accompanying documentation
Form: Freeze-dried or spray-dried powder; sometimes blended with carriers like maltodextrin or skim milk powder
CAS Number: 110423-15-9
Other Ingredients: Trace fermentation media residues possible, as stated in certificate of analysis

First Aid Measures

Inhalation: Move exposed person to fresh air; seek medical attention if cough, shortness of breath, or irritation persists
Skin Contact: Wash area thoroughly with soap and water; remove contaminated clothing
Eye Contact: Flush eyes gently with running water for at least 15 minutes; consult physician if irritation remains
Ingestion: Rinse mouth with water; rarely requires medical attention if consumed in normal probiotic doses

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide for bulk quantities
Unsuitable Extinguishing Media: None known for this material
Fire Hazards: Dust can form explosive mixture with air under certain conditions; keep storage areas clear of ignition sources
Protective Equipment: Firefighters should wear standard protective gear and use breathing apparatus
Combustion Products: Mainly carbon dioxide, water vapor, and trace organic compounds; low toxicity expected

Accidental Release Measures

Personal Precautions: Limit dust exposure; use respiratory protection in case of large spills
Environmental Precautions: Prevent release into water systems; large amounts may disrupt local balance
Cleanup Methods: Sweep up cautiously to prevent powder dispersal, place in suitable containers for disposal or recovery; avoid using water directly on powder spills due to potential agitation
Disposal: See Disposal Considerations section below for guidance

Handling and Storage

Handling: Minimize dust creation; handle with clean, dry gloves; avoid direct contact with eyes and skin; make sure to clean up any spills promptly
Storage: Store in cool, dry, well-ventilated area; keep containers tightly closed to protect from humidity and microbial contamination
Special Considerations: Avoid storage near sources of heat, sunlight, or strong oxidizers; refrigerate if specified by product guidelines to maintain cell viability
Incompatibilities: No significant chemical incompatibilities, but sensitive to extreme heat and moisture

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific regulatory exposure limits established
Engineering Controls: Use local exhaust ventilation to control airborne dust if handling bulk amounts
Personal Protective Equipment: Wear disposable gloves, lab coat, and goggles; use NIOSH-approved respirator if dust levels become significant
Hygiene Measures: Wash hands thoroughly after handling; avoid eating or drinking in work areas

Physical and Chemical Properties

Appearance: Off-white to light beige free-flowing powder
Odor: Faint, slightly sour fermentation smell
pH (1% suspension): Typically 5.0–7.0
Melting Point/Freezing Point: Not applicable (biological material)
Boiling Point: Not applicable
Solubility: Partially soluble in water; clumping may occur
Bulk Density: 0.3–0.6 g/cm³ depending on formulation
Flammability: Not highly flammable, but dust may combust in air
Decomposition Temperature: Degrades at sustained exposures above 50–60°C

Stability and Reactivity

Chemical Stability: Stable when stored in recommended conditions
Reactivity: Low under standard usage; not reactive with most materials
Hazardous Reactions: None expected under normal handling; avoid creating airborne dust concentrations
Conditions to Avoid: High humidity, heat, direct sunlight
Incompatible Materials: Strong acids, bases, oxidizing chemicals can degrade bacterial viability
Hazardous Decomposition Products: Not expected under intended use; extreme fire yields basic organic combustion byproducts

Toxicological Information

Acute Toxicity: No expected acute toxicity by oral, inhalation, or skin routes in healthy individuals
Chronic Toxicity: Long-term human data indicate safety in food and supplement use
Skin Corrosion/Irritation: May cause dryness or mild irritation after prolonged contact
Eye Damage/Irritation: Dust can cause temporary discomfort, redness, or itching
Respiratory Effects: Inhalation of dust may provoke coughing or throat irritation, especially in sensitive or atopic individuals
Sensitization: Contains no known allergens, but rare sensitization may occur
Carcinogenicity/Mutagenicity: Not carcinogenic or mutagenic based on available data; classified as Generally Recognized as Safe (GRAS) for food applications

Ecological Information

Environmental Fate: Degradable and non-persistent under most natural conditions
Bioaccumulation Potential: Does not bioaccumulate; survives only temporarily outside host environments
Aquatic Toxicity: Not toxic to aquatic life in small quantities; large discharges may temporarily alter natural microbial populations
Soil Impact: Adds beneficial bacteria to soil at controlled concentrations
Mobility in Soil: Low mobility; does not persist over extended periods

Disposal Considerations

Disposal Methods: Treat as non-hazardous biological waste; dispose of in accordance with local, state, and national regulations
Contaminated Packaging: Empty containers should be rinsed and disposed of responsibly; recycling encouraged where facilities exist
Precautions: Avoid disposal in bulk to wastewater systems; moderate amounts can go to landfill or compost depending on carrier ingredients
Regional Restrictions: Check local codes for handling of microbial cultures

Transport Information

UN Number: Not regulated for transport under international guidelines
Proper Shipping Name: Not restricted; use product name on documentation
Hazard Class: Not applicable
Packing Group: Not applicable
Special Transport Precautions: Protect from heat and moisture; avoid crushing containers; cold chain logistics may be needed for live culture products

Regulatory Information

Labeling Requirements: Follow food or feed labeling laws as appropriate; most jurisdictions require strain name and concentration
Chemical Inventories: Lactobacillus paracasei is exempt as a living organism but often listed in biological materials registries
GRAS Status: Approved for food use in most regions; recognized by US FDA and EFSA
Occupational Health Standards: No occupational exposure limits set by OSHA, ACGIH, NIOSH
Other Regulation: Subject to quality assurance schemes for probiotics and microbial food ingredients; batch records, viability testing, and traceability required by major regulatory bodies