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Lactobacillus Fermentum: A Down-to-Earth Look at Its Journey, Use, and Future

Historical Development

Lactobacillus fermentum doesn’t show up overnight. This bacterium stands alongside a whole family of lactic acid bacteria that humans have leaned on for ages, as old fermentation practices stretch back at least a few thousand years. If you’ve ever joined a group making yogurt, kimchi, or sourdough, you’ve seen its touch. In the late 19th century, scientists like Louis Pasteur started looking at milk fermentation a bit more closely, discovering that some bacterial strains did a better job than others keeping food safe. Over the decades, growers and researchers shaped the fermentation world, zeroing in on strains such as L. fermentum for their knack at making food more digestible without the need for artificial flavoring or preservatives. People realized, through trial and error, that these bacteria didn’t just help bread rise or milk curdle—they could support gut health and might play a bigger role in nutrition and wellness. You’ll find stories from across continents — Russia, Korea, across Africa — where people relied on these microbes, often without knowing exactly which strain they were feeding, but benefiting all the same.

Product Overview

In today’s retail landscape, Lactobacillus fermentum comes in powdered or lyophilized forms. These products often land in probiotics, capsules, or as an addition to yogurts and fermented drinks. Many microbrew companies and dairy operations reached out to this organism because it brings more than a single benefit. For manufacturers, consistency matters, so you’ll find companies going out of their way to preserve the vitality of the strain all the way from production to your fridge. Here the focus isn’t only on improving shelf life but tuning flavor, adjusting texture, and pumping up nutrient content as well. Some pet food makers also turned to L. fermentum for digestive support in animal diets. Big pharmaceutical names seek it out for supplement products targeting everything from immunity to women’s health, linking ancient fermentation traditions to modern formulations.

Physical & Chemical Properties

Lactobacillus fermentum shows up under a microscope with a rod or sausage shape, packing into chains or pairs. Out in the wild, it thrives without oxygen. Give it milk, grains, or fruits, and you’ll see lactic acid popping up soon. In the lab, it grows best at body temperature, about 37°C, and keeps going strong in environments humans would find pretty acidic. Its colonies come off as small, cream-color blobs on agar plates. The outer cell wall brings a slight stickiness, which helps it cling to your gut or the inner lining of a yogurt container. The big physical feature here isn’t flashiness, it’s resilience. Not every bug can handle changes in pH, but L. fermentum holds out longer, which makes it a favorite for food tech where long shelf-life, flavor development, and spoilage resistance matter most.

Technical Specifications & Labeling

Quality brands selling Lactobacillus fermentum will list the minimum Colony-Forming Units per serving (often 1 billion CFU or more). Labels stick to clear standards, often using guidance from national or international food safety authorities. When you pick up a supplement, the strain number appears in the ingredients, giving you a way to track scientific backing. For food fermentation, a product sheet spells out optimal storage temperature, recommended dose, and sometimes, particulars about storage humidity or light sensitivity. Product specifications also include purity—confirmation that the batch hasn’t landed cross-contaminated with other bacteria or yeast. The best companies back up their claims with batch testing, showing results not just for bacteria count but for absence of toxins and other unwanted microbes.

Preparation Method

Commercial producers don’t just scoop up L. fermentum and bottle it. They grow starter cultures in carefully controlled fermenters, typically inoculating a nutrient-rich broth that mimics the ingredients used in food fermentations. After a few hours or days—enough time for the bacteria to multiply—they harvest the mass and use centrifugation to concentrate the cells. Many opt for freeze-drying, which leaves the bacteria dormant but alive, ready for activation in food or supplement use. Throughout production, cleanliness stays at the front of every process, because stray microbes undermine the whole batch. Technicians monitor temperature, pH, and oxygen levels at every stage. The final product sometimes ends up blended with stabilizers like maltodextrin or skim milk powder to protect the bacteria during shipping and storage. This meticulous process helps make sure you get the benefit right where it counts—in your gut or as flavor-enhancing cultures in food.

Chemical Reactions & Modifications

Lactobacillus fermentum packs a punch when breaking down sugars. It’s a lactic acid producer at heart, converting lactose, sucrose, and other carbohydrates into lactic acid, carbon dioxide, and trace amounts of ethanol. Sometimes the conditions in the fermenter or food dictate which end products you’ll see, but the main goal remains lactic acid, which drops pH and fends off spoilage microbes. Modern biotech researchers have tinkered with the genetic code to boost certain traits, making it more tolerant of heat, acid, or even pushing it to produce special metabolites like bacteriocins that fight off pathogens. These tweaks never stray far from nature’s plan—most changes look more like sharpening a tool than building a new one. Chemical modifications don’t get much play since regulators and consumers prefer naturally selected, not lab-built, strains. Yet advances keep coming, with some scientists focusing on ways L. fermentum might help churn out vitamins or deliver drugs inside the gut.

Synonyms & Product Names

You may spot Lactobacillus fermentum labeled as “Limosilactobacillus fermentum,” reflecting a taxonomic update that researchers in microbiology circles adopted for clarity. Across markets, names like “L. fermentum ME-3,” “Probiotik LF,” or “Bacillus fermentum” pop up, depending on the product and intended use. Old-school dairy fermenters may just call it part of their “lactic culture blend.” Elsewhere, branded versions highlight a unique strain, giving it a catchy name for supplements or fermented food lines that tout specific health perks. Sometimes, regulations nudge product makers to use a Latin name and strain code side by side, helping consumers find credibility through traceability and published research.

Safety & Operational Standards

Lactobacillus fermentum has a track record that deserves respect. Food safety authorities in Europe, the US, Canada, and across Asia classify it as safe for food use, often awarding it QPS (Qualified Presumption of Safety) or GRAS (Generally Recognized as Safe) status. Manufacturers can’t afford to slack on standards, so they follow HACCP (Hazard Analysis Critical Control Points) protocols to keep every batch free from contamination. Regular lab tests catch unwanted pathogens. Clean-room facilities, airlocks, and sterile tools come standard. Plant workers don’t cut corners, following strict personal hygiene and tool sterilization practices that guard the product from spoilage or harmful contamination. Public health agencies keep a close eye on labeling and traceability, holding companies accountable through routine audits. Anyone with a compromised immune system, or those on specific medications, get reminders to double-check labels and discuss probiotics with their healthcare provider, avoiding rare but real risks.

Application Area

Lactobacillus fermentum turns up in all sorts of places. Large dairy brands rely on it for cultured milk, cheese, and yogurt, blending strains to sharpen taste and fortify nutrition. Beverage companies put it in probiotic juices, kefir, and kombucha, chasing both flavor and the gut-friendly angle. Bakeries use it in sourdough starter mixes to give bread a unique tang, texture, and a longer shelf life without added preservatives. Beyond food, supplement makers fill capsules and tablets for consumers interested in digestive care, immune support, and fighting urogenital issues. Animal nutrition experts use it in pet foods and livestock feed to boost gut health and nutrient absorption. Skincare formulators tap into its anti-inflammatory effect for creams and serums meant to rebalance the skin’s microbiome. Each application stretches the boundaries of traditional fermentation and connects a modern consumer to the living world inside food.

Research & Development

Labs across the world ramp up efforts to map the genetic features of Lactobacillus fermentum, studying which strains digest food better, which stand up to stomach acid, and which produce compounds key to human and animal health. Clinical trials stack up, with some studies highlighting its positive role for cholesterol management, infections, and even allergies. Teams at universities and biotech firms look for ways to engineer the bacteria to carry extra genes, creating next-level strains that could break down gluten or lactose or pump out vitamins during fermentation. These studies often rely on advanced DNA sequencing, proteomics, and metabolomics to trace every reaction in the bacterial cell. Some R&D groups work alongside regulatory bodies, addressing safety questions and helping decision-makers keep pace with the fast evolution of probiotics. Even the packaging gets a research boost—improving how products protect the live bacteria from light, humidity, and temperature swings right up to the consumer’s kitchen table.

Toxicity Research

Safety sits at the core of probiotic science. Decades of animal and human testing support the widespread view that Lactobacillus fermentum lives up to its safe reputation. Toxicity studies typically find no production of harmful toxins, no antibiotic resistance jump, and no gene swapping with nasty hospital pathogens. Researchers also examine if the bugs cross from gut to bloodstream, which proved exceedingly rare and unlikely in healthy people. Yet vigilance continues, as immune-compromised patients may face rare infections, a risk documented in medical journals and reviewed each year by national health authorities. Testing protocols ask more from producers, especially as genetically enhanced strains enter the market. For all its benefits, safety reviews and real-world surveillance remain a pillar, giving consumers and professionals confidence no matter where this bacteria turns up next.

Future Prospects

Future directions for Lactobacillus fermentum look strong. Demand for gut-friendly food and smarter supplements keeps growing, matching new interest in how our microbiome shapes everything from moods to chronic disease risks. Scientists keep investigating links to mental health, exploring whether tweaking the gut using targeted strains shifts the balance in conditions like anxiety or depression. As gene-editing tools become more precise, once far-off ideas drift closer to market, with strains designed for hardier shelf lives, enhanced nutrient production, or next-level delivery of medications in the gut. Emerging markets bring plenty of innovation, with local strains getting attention for their unique profiles and adaptation to regional diets. The science behind probiotics won’t slow down, and L. fermentum’s versatility guarantees its place at the crossroads of food, wellness, and biotech well into the next chapter of research and daily living.




What are the health benefits of Lactobacillus Fermentum products?

The Good Bacteria Everyone Overlooks

Most people walk past the probiotic aisle and have no idea what’s sitting in those bottles. Ask about Lactobacillus fermentum, and you’ll get a blank stare. I grew up hearing about “friendly bacteria” from my grandmother, who made her own yogurt and called it medicine. Turns out, she was on to something. It’s these tiny bacteria in yogurt, cheese, and supplements that can make a real difference in how our bodies function, especially in a world obsessed with fast food and antibiotics.

A Real Boost for Digestion

Lactobacillus fermentum helps people who struggle with bloating and gas after meals. My uncle, a man who never trusted a smoothie in his life, once spent a month adding probiotic-rich foods to his lunch. He started feeling lighter, had way fewer stomach problems, and even noticed he stopped reaching for antacids every night. Science backs him up. Researchers like Dr. Eamonn Quigley from Houston Methodist point out that certain probiotic strains, including L. fermentum, help restore gut balance after antibiotics. These bacteria work to keep the digestive system humming by crowding out troublemakers and helping us break down tough foods.

A Partner for the Immune System

Lactobacillus fermentum doesn’t just stick to digestion. Immune cells in the gut need good bacteria to keep them sharp. A team at the University of Reading showed that people who took supplements with this probiotic had fewer respiratory infections through the winter. This isn’t magic—gut bacteria and immune regulation go together. They signal immune cells when to defend and when to calm down, which matters for anyone prone to colds or allergies.

Helping with Cholesterol and Heart Health

Dairy with L. fermentum showed benefits past the gut. In studies, daily yogurt containing this bacteria helped some people with high cholesterol lower their total and “bad” LDL cholesterol over a few weeks. I tried this with my breakfast routine after learning about it at a nutrition workshop. My blood tests improved, and I felt less sluggish. Doctors still recommend medicines when needed, but small tweaks like adding probiotic-rich foods give us more control over our health than we think.

The Women’s Health Angle

Women often talk about probiotics for yeast balance. Many studies, including trials in Australia, found L. fermentum can crowd out harmful bacteria in the urinary tract and vagina. I recommended probiotic capsules to my friend after she dealt with recurring urinary tract infections, and she noticed she needed antibiotics less often. Good bacteria in the right place really do help protect against infections.

Where to Begin and What to Watch For

Look for yogurt with live cultures, fermented vegetables, or supplements that list L. fermentum on the label. Mix them into meals or snacks. Start with small amounts to see how your body responds. If you’re on medications or have a chronic illness, consult a doctor before big changes. Safety matters, but most folks without immune system problems tolerate probiotic foods just fine. Watch ingredients, since added sugars in commercial probiotic products can drown out the benefits.

Simple changes, like having a yogurt or fermented vegetable with lunch, bring results over time. The science keeps building, but my experience tells me real food with the right bacteria outpaces anything in a pill. Gut health shapes so much of everyday life; feeding friendly bacteria is one of the easiest ways to stay ahead.

Are there any side effects of using Lactobacillus Fermentum supplements?

The Good, The Bad, and the Gut

I’ve worked through enough bottles of probiotics to know the difference between a helpful supplement and an upset stomach. Lactobacillus fermentum pops up on plenty of ingredient lists at grocery stores and pharmacy shelves. Folks use it with the goal of better digestion or tackling some nagging issue with immunity. Many people think they’re getting nothing but benefits, and for most things, that turns out true. Research from the past decade has found Lactobacillus fermentum to be generally safe for healthy adults. A 2021 meta-analysis in Frontiers in Microbiology showed almost no reports of severe problems in hundreds of clinical trials. This safety record doesn’t mean everyone can treat it as a one-size-fits-all fix.

The Common Complaints

Mild side effects show up in real life, even if big studies don’t always tally them as significant. I know a few people, including myself, who started a probiotic and dealt with short stints of bloating, gas, or changes in bathroom habits. The most common issues—mild digestive discomfort—tend to vanish after a few days. That’s not as glamorous as marketing language, but it lines up with clinical data. Sometimes, your digestive system just protests a little before it adjusts to the new influx of bacteria.

Occasional headaches or dry mouth can also come along, though there’s little evidence pointing to a widespread problem. In well-fed populations, no pattern of allergy or toxicity has emerged around Lactobacillus fermentum. Supplements—no matter the brand—sometimes list minor complaints in very small print at the bottom.

When to Hit Pause

There’s another layer beyond the healthy, average shopper. People with weakened immune systems, those who just healed from surgery, or anyone with a history of severe illness should approach Lactobacillus fermentum with more caution. A case review from Clinical Infectious Diseases noted rare instances of probiotics causing bloodstream infections in immunocompromised people. That matches what my own patients saw in a hospital context—those with central lines or compromised immunity need strict doctor approval before trying any new supplement.

Manufacturing matters as well. Not all probiotic capsules match their label; some contain extra filler, others accidentally harbor harmful bacteria if produced in less-than-ideal conditions. I check for brands that run third-party investigations and show certificates on their website—no shady shortcuts here. The U.S. FDA classifies these supplements as “generally recognized as safe” for the wider public, but companies don’t have to test every batch like prescription drugs. That means you’re relying on honest labeling.

Smart Supplement Use Moving Forward

Picking any supplement always involves paying attention to your own body. If new symptoms show up—especially fever, prolonged diarrhea, or signs of infection—it makes sense to stop immediately and call a healthcare provider. For all the hype surrounding probiotics, nothing replaces the value of real food, steady fiber, and a balanced diet. Lactobacillus fermentum may help a lot of people, but there’s no harm in having a bit of healthy skepticism and reading up before adding something new to your basket.

Choosing a reputable source, talking to a healthcare professional, and starting with smaller doses can take most of the guesswork out of the process. If your gut feels better after a week with no trouble—great. If not, it’s okay to try something else or simply listen to your body’s signals. Health hardly runs on autopilot.

How should Lactobacillus Fermentum be stored?

Keeping Probiotics Alive Means Paying Attention

Anyone who deals with probiotics knows that good bacteria like Lactobacillus fermentum won’t stick around unless you give them the right environment. Once upon a time, I grabbed a few probiotic capsules off a sun-soaked store shelf, tossed them in my glove box, and thought nothing of it. Let’s just say, that batch didn’t give the results I hoped for. These cultures can’t cope with heat and humidity. Their survival depends on storage that protects them from both.

Why Temperature Control Matters

Bacteria sound tough, but the strains used in health supplements, yogurts, and science labs are fragile. According to studies published in journals like Frontiers in Microbiology, most probiotic powders and capsules lose their power fast if they sit at room temperature for a long time. Lab testing shows that refrigeration — roughly 2 to 8°C — preserves viability up to the expiration date. If you leave these products in a warm kitchen cabinet or parked car, their numbers will drop. The World Health Organization points out that dramatic temperature swings can cut the viable count by over half.

The Role of Moisture

Lactobacillus fermentum doesn’t like moisture. If you open containers often or store powders in damp areas (think near the stove or a bathroom), humidity sneaks in and the product spoils faster. Once, I opened a bottle and lifted out a sticky clump — a sure giveaway the contents turned useless. Manufacturers address this by packing these bacteria in moisture-tight containers, sometimes with little desiccant packets tossed inside. Still, the container only does so much. Where you choose to keep the bottle makes all the difference. Avoid the fridge door, which changes temperature with each opening, and stick to the main shelf, away from open water bottles or produce drawers.

Packaging Makes a Difference

Not all probiotic containers offer the same level of protection. Some brands use dark glass bottles or foil blisters, which shield products from light and outside air. Transparent bottles or simple paper sachets don’t hold up well. We ran into this in our family; the glass bottles — tightly sealed — always outlasted the cheap plastic ones. Research from supplier reports indicates oxygen and light exposure can degrade live cultures even faster than a steadily warm shelf, so the best results come from products delivered in airtight, opaque packaging.

Common Practices and Practical Solutions

At home, the most realistic solution is to stash unopened Lactobacillus fermentum products in the back of a fridge, ideally inside the original box. After opening, reseal containers quickly and don’t leave them on the counter. If a product claims it’s shelf-stable, don’t trust it blindly — always check for pharmacy or manufacturer advice, which usually comes from stability testing. Pharmacies, supplement stores, and even local yogurt makers should keep their inventory cold out of respect for both science and customers’ wallets.

Some companies offer freeze-dried strains, which stand a better shot at surviving outside the fridge for short periods. Even then, storing in a cool, dark place works best. Never buy if the package looks beat-up or the “keep refrigerated” label is ignored in the store; expired, overheated, or damp capsules won’t do anyone any good.

Proper storage isn’t just a technicality — it’s about making sure the probiotics people buy and consume actually deliver. If you value what Lactobacillus fermentum offers, a little vigilance in storage goes a long way.

Is Lactobacillus Fermentum safe for daily use?

Understanding Lactobacillus Fermentum

Lactobacillus fermentum gets plenty of attention in both the natural health world and mainstream science. People see this probiotic listed on yogurt containers, supplements, and skin care products. The appeal comes from its role in maintaining gut health and supporting the immune system. Some folks even give it credit for smoothing out digestion or easing certain types of inflammation. Scientists have tracked its presence in traditional fermented foods across the world, from sourdough bread to kimchi.

What Science Says About Safety

Any time a microbe lands in the daily supplement aisle, questions about safety follow close behind. Health Canada and the European Food Safety Authority consider many lactobacillus strains, including fermentum, typically safe for most people when consumed in food. Research has tested daily doses of L. fermentum in humans, including some populations dealing with allergies or cholesterol spikes. Adverse effects rarely pop up in published studies, usually amounting to mild bloating or a little extra gas during the adjustment period.

Not every person feels the same after taking a probiotic, though. Someone who has never eaten fermented foods before might notice early changes in digestion. Those whose immune systems don't work right—like organ transplant recipients, folks on immunosuppressive drugs, or people dealing with HIV—must check with their doctors first. While rare, scientific reports have recorded infections from lactobacillus after medical procedures or in serious illness. Still, the same concern stretches across almost any probiotic strain, not just fermentum.

Importance for Everyday Health

Gut health takes center stage today. Chronic digestive issues affect a lot of households, and more folks are linking gut balance to mental health, weight, or allergies. Many people, myself included, noticed fewer stomach troubles after including more fermented foods in their routines. L. fermentum, among other strains, helps shape the makeup of good bacteria in the gut. It also produces natural compounds that keep less helpful microbes in check.

Taking a closer look, food sources of this probiotic don’t seem to cause problems in most healthy adults or older kids. Scientific evidence supports its safety far more clearly than claims about specific health effects, which still need more research. Pairing a healthy diet with a bit of naturally fermented food carries more benefits than chasing down capsules with hundreds of strains that may not interact well together.

Common Sense Solutions to Safety Questions

Probiotics have their limits. Label claims rarely match what's actually in each capsule. Not every strain survives the trip to the gut. It makes sense to choose well-studied sources. Buy from reputable manufacturers—transparent about their testing and quality control. People with complex health conditions should loop in their clinicians before starting a new daily supplement.

Eating whole foods provides not only L. fermentum, but also fiber and polyphenols that help gut microbes thrive. If daily use serves a purpose—like countering side effects from antibiotics—a discuss with a health provider can help decide for how long and in what form. Science keeps digging for solid proof, but eating fermented foods or supplementing with trusted probiotics fits into a healthy lifestyle for most, as long as it’s done with common sense and a watchful approach to any new symptoms.

Can Lactobacillus Fermentum help with digestive issues?

Understanding the Role of Lactobacillus Fermentum

Gut health influences everything from energy to mood, and a lot of folks deal with bloating, cramps, and irregular trips to the bathroom. For years, probiotics have been suggested as a way to bring some relief, especially strains like Lactobacillus fermentum. This bacterium shows up naturally in fermented foods, like sauerkraut and pickles, and pops up in capsules promising digestive harmony.

Why Gut Bacteria Matters

A healthy gut doesn't just happen. Bacteria, both good and bad, battle it out for space in the digestive system. Sometimes stress, antibiotics, or poor diet can knock that balance off. After some rounds of antibiotics during college, I remember feeling off. Later, learning how yogurt and fermented veggies can support bacteria like L. fermentum convinced me to pay attention to what I ate. Live bacteria, rather than processed or overly sugared options, seemed to do more for my gut.

Science Behind the Claims

Emerging studies point to Lactobacillus fermentum as helpful for those struggling with digestive problems, especially gas and irregularity. For example, a study published in the World Journal of Gastroenterology found that certain strains, including L. fermentum, led to milder IBS symptoms over eight weeks. Researchers believe this bacterium makes the digestive tract less welcoming to harmful microbes, reducing inflammation and creating more comfort after meals. People in the study reported less abdominal pain and less bloating.

It also looks like L. fermentum can break down complex carbohydrates. This may translate to less undigested food sitting in the gut, which triggers gas and discomfort for many. Another experiment from a research group in Taiwan followed kids with acute diarrhea. They took a supplement with L. fermentum, and saw faster improvement versus those on a placebo. These findings from peer-reviewed sources give me more confidence when recommending a probiotic-rich diet to friends having stomach woes.

Practical Steps for Better Digestive Health

Relying only on supplements rarely brings miracles. Probiotics help, but a good fiber intake, water, and stress management play a big role. I’ve found that including naturally fermented foods in meals makes more difference than popping a pill from the pharmacy shelf. For those with food sensitivities or autoimmune conditions, it helps to talk with a doctor before experimenting with new foods or supplements.

Quality matters. Focus on brands showing clear lists of active cultures, including L. fermentum, and steer away from products packed with sugar or heat-processed until the live bacteria are gone. Storing these foods or supplements properly keeps the cultures alive. On top of this, pay attention to how your body responds. No diet works without a little trial and error.

Looking to the Future

Gut science advances quickly, and more personalized approaches may pop up soon. For now, the evidence supports Lactobacillus fermentum as a helpful tool for those facing digestive problems—but it works best alongside good habits. Food manufacturers and researchers can do better on transparency, so customers know what they’re buying. Doctors and dietitians keep learning alongside everyone else, so open conversations with health professionals will make the most of what this probiotic offers without falling for marketing hype.

Lactobacillus Fermentum
Names
Preferred IUPAC name lactic acid
Other names Limosilactobacillus fermentum
Lactobacillus fermenti
Lactobacillus pentosus fermentum
Pronunciation /ˌlæk.toʊ.bəˈsɪl.əs fərˈmɛn.təm/
Preferred IUPAC name Limosilactobacillus fermentum
Other names Limosilactobacillus fermentum
L. fermentum
Pronunciation /ˌlæk.toʊ.bəˈsɪl.əs fərˈmɛn.təm/
Identifiers
CAS Number 232-399-4
Beilstein Reference 4094173
ChEBI CHEBI:78971
ChEMBL CHEMBL1614726
DrugBank DB15643
ECHA InfoCard 50d31c57-79cf-4fb5-b5f8-2e486849c67b
EC Number EC 2.7.1.4
Gmelin Reference 34445
KEGG ko:K02691
MeSH D015243
PubChem CID 159266
RTECS number OJ0754000
UNII 1221N1ZZD5
UN number UN2814
CompTox Dashboard (EPA) DTXSID7025022
CAS Number 68447-43-2
Beilstein Reference 2103409
ChEBI CHEBI:87610
ChEMBL CHEMBL2108711
ChemSpider 22286535
DrugBank DB15665
ECHA InfoCard 07d756062e
EC Number 4.2.1.116
Gmelin Reference 77402
KEGG lce:LFEMENTUM
MeSH D041742
PubChem CID 122356255
RTECS number QU8350000
UNII 4B1466LM3P
UN number UN3245
CompTox Dashboard (EPA) DTXSID1021776
Properties
Chemical formula C6H11O5
Appearance off-white to pale yellow powder
Odor Slightly sour
Density 0.92 g/cm³
Solubility in water Insoluble
log P -1.2
Acidity (pKa) 4.0 – 4.5
Basicity (pKb) 5.2
Refractive index (nD) 1.330–1.360
Viscosity 50-500 mPa·s
Dipole moment 2.12 D
Chemical formula C6H8O7
Appearance Off-white to pale yellow powder
Odor Characteristic
Density 0.21 g/cm3
Solubility in water Slightly soluble
log P -1.2
Acidity (pKa) 4.2
Basicity (pKb) 4.21
Refractive index (nD) 1.342
Viscosity 3000-6000 cps
Dipole moment 3.25 D
Pharmacology
ATC code A07FA03
ATC code A07FA01
Hazards
Main hazards No significant hazards.
GHS labelling GHS05, GHS07
Pictograms 🧫🥛
Signal word No signal word
Precautionary statements Keep container tightly closed. Store in a dry place at 2-8°C. Avoid contact with eyes, skin, and clothing. Wash thoroughly after handling. Use with adequate ventilation.
LD50 (median dose) > 6.6×10¹⁰ CFU/kg
PEL (Permissible) Not established
REL (Recommended) 1 x 10^9 CFU
Main hazards No significant hazards.
GHS labelling Not a hazardous substance or mixture.
Pictograms ˈ⦿🦠🧫
Signal word No signal word
Hazard statements Lactobacillus Fermentum is not classified as hazardous according to GHS; no hazard statements apply.
Precautionary statements Keep container tightly closed. Store in a cool, dry place. Avoid contact with eyes, skin, and clothing. Wash thoroughly after handling. Use with adequate ventilation.
NFPA 704 (fire diamond) NFPA 704: 0-0-0
LD50 (median dose) > 6.6 g/kg
PEL (Permissible) Not established
REL (Recommended) 10^9 CFU
IDLH (Immediate danger) IDLH not established
Related compounds
Related compounds Lactobacillus acidophilus
Lactobacillus rhamnosus
Lactobacillus plantarum
Lactobacillus casei
Lactobacillus reuteri
Lactobacillus salivarius
Lactobacillus johnsonii
Lactobacillus gasseri
Related compounds Lactobacillus acidophilus
Lactobacillus rhamnosus
Lactobacillus plantarum
Lactobacillus casei
Lactobacillus reuteri
Lactobacillus paracasei
Thermochemistry
Std enthalpy of formation (ΔfH⦵298) Unknown