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Material Safety Data Sheet: Lactobacillus Acidophilus

Identification

Product Name: Lactobacillus acidophilus
Synonyms: L. acidophilus, Acidophilus bacteria
Manufacturer: Refer to specific supplier documentation
Product Use: Probiotic supplement, food additive, industrial fermentation process
Contact Information: Supplier or distributor’s emergency number provided on package insert
CAS Number: 68333-16-4
EC Number: 269-264-6
Recommended Use Restrictions: Not for use beyond intended microbiological or dietary application

Hazard Identification

Hazard Classification: Not classified as hazardous under Globally Harmonized System (GHS)
Potential Health Effects: May trigger allergies in sensitive individuals, rare respiratory issues after inhalation of large amounts of powder, irritation possible in eyes or on prolonged skin contact
Environmental Hazards: No known significant environmental hazard
GHS Label Elements: Not required
Precautionary Statements: Prevent direct inhalation, avoid contact with eyes, use hygiene practices to limit spread

Composition / Information on Ingredients

Chemical Name: Lactobacillus acidophilus
Concentration: May range from 107 to 1011 CFU/g depending on formulation
Other Components: Growth media residues, trace water, stabilizers (e.g., maltodextrin, inulin), possible carriers such as trehalose or silica
Impurities: Absent, antimicrobial screening performed prior to release
Hazardous Components: None present above safety thresholds stated by GHS

First Aid Measures

Inhalation: Remove to fresh air, seek medical attention if symptoms (such as coughing, difficulty breathing) persist
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, contact physician if irritation develops
Eye Contact: Rinse eyes continuously with water for several minutes, remove contact lenses if present, seek help if discomfort continues
Ingestion: Product intended for consumption at low doses; excessive accidental ingestion: consult medical advice if feeling unwell
Notes to Physician: Symptomatic treatment, monitor for allergic reaction signs in sensitive individuals

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, carbon dioxide (CO2), dry powder
Unsuitable Extinguishing Media: No specific restrictions identified
Specific Hazards Arising from Product: Decomposition could release low levels of carbon oxides or nitrogen oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear advised
Special Procedures: Move containers away from fire if safe

Accidental Release Measures

Personal Precautions: Avoid raising dust, wear gloves and eye protection, ventilate area
Environmental Precautions: Prevent entry into watercourses or drains
Containment: Sweep or vacuum up spills using tools that avoid dust generation
Cleanup Methods: Place material in lidded containers for disposal, wash affected surface with water
Decontamination: Use routine detergents and water to clean area thoroughly

Handling and Storage

Safe Handling Guidelines: Keep container tightly closed, avoid inhaling powder, minimize dust, observe good hygiene
Storage Conditions: Store in cool, dry, well-ventilated area, away from direct sunlight or sources of moisture; refrigeration prolongs shelf-life
Packaging Materials: Food-safe, airtight packaging preferred
Incompatibilities: Strong acids, strong base conditions, significant heat
Special Requirements: Handle using clean utensils to prevent cross-contamination

Exposure Controls and Personal Protection

Occupational Exposure Limits: No exposure limits set for Lactobacillus species
Engineering Controls: Local exhaust ventilation, or laminar flow hoods in large-scale use
Personal Protective Equipment: Gloves, protective eyewear, N95 mask in powder-heavy environments
Hygiene Measures: Wash hands after handling, avoid eating and drinking in work areas
Environmental Controls: Use spill containment procedures to prevent microbial aerosol spread

Physical and Chemical Properties

Appearance: Off-white to beige powder or granular material
Odor: Slight, characteristic fermented note
pH (1% solution): 5.5–7.5
Boiling Point / Range: Not applicable (non-liquid)
Melting Point / Range: Not applicable
Solubility: Partially dispersible in water
Bulk Density: 0.3–0.7 g/cm3
Stability in Air: Stable, deactivates under high temperature and humidity

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: No hazardous reactions under normal use
Conditions to Avoid: High moisture, heat exceeding 30°C, direct sunlight
Materials to Avoid: Strong oxidizing agents, strong acids and alkalis
Hazardous Decomposition Products: Thermal decomposition may release trace organic vapors and carbon oxides

Toxicological Information

Acute Toxicity: No known toxicity; GRAS (Generally Recognized As Safe) for intended use
Chronic Exposure: No adverse health effects documented from prolonged exposure at recommended doses
Inhalation: Dust may irritate respiratory system if inhaled in large amounts
Skin/Eye Contact: May cause minor irritation in some people
Allergenic Potential: Possible hypersensitivity responses in individuals with allergy to lactic acid bacteria

Ecological Information

Eco-toxicity: No known eco-toxic effects, non-pathogenic microorganism
Mobility: Limited in soil and aquatic environments – unlikely to bio-accumulate
Persistence and Degradability: Readily biodegradable; typical environmental microflora breakdown
Bioaccumulative Potential: Does not bio-accumulate
Other Adverse Effects: No negative impacts reported on flora or fauna

Disposal Considerations

Product Disposal: Dispose of in accordance with local, regional, national, international regulations for organic biowaste
Contaminated Packaging: Clean containers can be recycled or disposed according to local protocols
Special Disposal Precautions: Avoid excessive discharge into sewage, surface waters, or groundwater
Recommended Disposal Method: Landfilling in biosecure site or controlled composting

Transport Information

UN Number: Not regulated
Proper Shipping Name: Lactobacillus acidophilus preparation
Transport Hazard Class: Not applicable
Packing Group: Not regulated
Special Transport Precautions: Protect from excessive heat and moisture during transit

Regulatory Information

Regulatory Status: Recognized as a safe food additive and supplement in most food safety jurisdictions (FDA, EFSA)
Labeling Standards: Complies with international food and feed ingredient legislation
Inventory Status: Listed or compliant with chemical inventories in U.S., EU, Australia, Canada, and Japan
Worker Protection: Covered under general occupational biosafety rules
Restrictions: Intended use only for approved food, supplement, fermentation, or research purposes