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Product Name: L-Valine
Chemical Formula: C5H11NO2
Synonyms: Valine, (S)-2-Amino-3-methylbutanoic acid
Molecular Weight: 117.15 g/mol
CAS Number: 72-18-4
Recommended Uses: Amino acid supplement for nutrition, laboratory chemical, food additive, feed additive
Supplier information: Manufacturer and distributor contact details on shipping label or company documentation
Emergency contact: Refer to local regulations for regional emergency numbers and procedures
Product Code: Specified on container label and accompanying shipment documents
GHS Classification: L-Valine does not meet the criteria for classification as hazardous under GHS
Signal Word: None
Hazard Statements: Product is not considered hazardous under normal handling, but inhalation of dust or ingestion of excessive amounts can produce mild irritation
Precautionary Statements: Avoid creating dust, wear protective gear if exposure risk is elevated, maintain good personal hygiene practices
Potential Health Effects: Inhalation can cause throat or respiratory irritation, contact with eyes or skin may cause slight discomfort, ingestion of dietary quantities is not dangerous but overdose may bring gastrointestinal symptoms
Label Elements: No label elements mandated for non-hazardous classification; precautionary steps printed as per region
Chemical: L-Valine
CAS Number: 72-18-4
EC Number: 200-773-6
Purity: Typically greater than 98% by weight in food grade and feed grade material; impurities and stabilizers at levels below reporting threshold
Other Ingredients: No hazardous components or additives in standard formulations
Inhalation: Move individual to fresh air, offer water to soothe throat, seek medical help if symptoms persist
Eye Contact: Rinse eyes thoroughly with plenty of running water for several minutes, remove contacts if worn and easy to remove, get medical attention if irritation continues
Skin Contact: Wash off with soap and water, remove contaminated clothing and wash before reuse
Ingestion: Drink water to dilute, do not induce vomiting, seek medical advice for large accidental ingestions or if feeling unwell
Medical Attention Needed: Not usually required, but available if irritation or discomfort remains
Note to Physicians: Treat symptomatically based on patient’s condition
Suitable Extinguishing Media: Foam, water spray, dry chemical, carbon dioxide
Hazards from Combustion Products: Can release carbon oxides, nitrogen oxides with incomplete combustion
Special Protective Equipment: Firefighters should wear full protective clothing, self-contained breathing apparatus
Specific Hazards: Powdered L-Valine can form combustible dust-air mixtures, avoid dispersion of dust in air
Firefighting Instructions: Keep contaminated water out of drains and water sources, cool containers by spraying with water if fire exposed
Personal Precautions: Avoid breathing dust, ventilate area, use protective equipment
Environmental Precautions: Prevent release into drains, sewers, or waterways where possible
Methods for Cleanup: Sweep up material, avoid generating airborne dust, place in labeled waste container for recovery or proper disposal, wash area with water to remove residues
Spill Response: Wear gloves and dust mask if large volumes spilled, contain and collect dry, dispose as per local waste management guidelines
Safe Handling: Use with adequate ventilation, keep container tightly closed, avoid production of airborne dust
Protective Measures: Prevent ingestion, inhalation, and skin or eye contact, practice good hygiene and clean work clothes
Storage Conditions: Store in cool, dry, well-ventilated place away from incompatible substances such as oxidizing agents, keep containers sealed and labeled
Storage Temperature: Room temperature (20–25°C)
Incompatibilities: Strong oxidizing chemicals
Storage Class: General chemical storage, food/feed additive storage procedures
Occupational Exposure Limits: No established limits for L-Valine; minimize exposure to dust
Engineering Controls: Ensure good ventilation, use local exhaust to control dust at source
Personal Protective Equipment: Use approved dust mask or respirator for heavy exposure, safety goggles, lab coat or overalls, gloves for prolonged handling
Hygiene Measures: Wash hands and face after handling, do not eat, drink, or smoke in processing areas, change work clothing if contaminated
Appearance: White crystalline powder
Odor: Odorless
pH (1% solution): Approximately 5.5–7.0
Melting Point: 298–300°C with decomposition
Solubility in Water: Soluble (approximately 8.5 g/100 mL at 25°C)
Boiling Point: Not applicable (decomposes before boiling)
Density: 1.23 g/cm³
Partition Coefficient (n-octanol/water): -2.26
Vapor Pressure: Negligible at ambient temperatures
Flash Point: Not relevant (non-flammable solid under standard conditions)
Chemical Stability: Stable under normal handling and storage conditions
Thermal Decomposition: Decomposes at high temperature, especially above 300°C
Reactivity: No hazardous polymerization under recommended conditions
Conditions to Avoid: High humidity, excessive heat, exposure to strong oxidizers
Incompatibility: Strong oxidizing agents such as peroxides and chlorates may react
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides on strong thermal decomposition
Acute Toxicity Data: Low toxicity in animal studies; oral LD50 in rats reported above 10,000 mg/kg
Inhalation: Dust may irritate respiratory tract
Skin Contact: Not suspected to cause harmful effects
Eye Contact: Slight transient irritation possible
Chronic Toxicity: Not identified as a carcinogen, mutagen, or reproductive hazard; no observed adverse effect in long-term dietary use at nutritional levels
Other Health Effects: Excessive intake can result in imbalances affecting metabolism, greatest concern exists if individual has underlying metabolic disorders affecting amino acid absorption or excretion
Ecotoxicity: L-Valine is a naturally occurring amino acid; no evidence of acute toxicity to aquatic or terrestrial organisms at concentrations expected in the environment
Persistence and Degradability: Readily biodegradable, metabolized by microorganisms in soil and water
Bioaccumulation Potential: Not expected to bioaccumulate, low partition coefficient in aquatic systems
Mobility in Soil: Water-soluble, will migrate through soil, but rapidly degrades through natural processes
Other Harmful Effects: No known significant adverse environmental impact, does not contribute to ozone depletion or global warming
Waste Disposal Methods: Dispose as non-hazardous organic waste in line with local regulations, large amounts may be handled as general laboratory or production waste
Container Disposal: Rinse and recycle or dispose of containers responsibly according to municipal guidelines
Special Instructions: Avoid uncontrolled discharge to environment, do not flush into drains, sewers, or waterways
UN Number: Not regulated
Proper Shipping Name: Not regulated as dangerous goods
Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not classified as marine pollutant or environmentally hazardous
Special Precautions for User: Basic shipping protections apply, avoid rupture or excessive dusting, ship in sealed, labeled containers
Safety Regulations: Not listed as hazardous by OSHA, WHMIS, GHS, or most national standards
TSCA Status: Listed
DSL/NDSL (Canada): Listed
REACH (EU): Exempt, naturally occurring substance
Label Requirements: Standard product labeling with trade name and manufacturer
Other Regulations: Meets GRAS (Generally Recognized As Safe) status for food use in the United States, permitted as a feed additive by major regulatory agencies worldwide
West Ujimqin Banner, Xilingol League, Inner Mongolia, China
