West Ujimqin Banner, Xilingol League, Inner Mongolia, China sales9@alchemist-chem.com 1531585804@qq.com
Follow us:



Material Safety Data Sheet for L-Serine

Identification

Product Name: L-Serine
Synonyms: 2-Amino-3-hydroxypropanoic acid
Chemical Formula: C3H7NO3
CAS Number: 56-45-1
Recommended Uses: Laboratory chemical, reagent, pharmaceutical intermediate, food supplement
Manufacturer Identification: [Manufacturer’s contact information as per local regulation]
Emergency Contact: [Local emergency number]

Hazard Identification

Hazard Classification: Not classified as hazardous according to GHS
Physical Hazards: Not expected to present a fire or explosion hazard
Health Hazards: May cause mild irritation to eyes, skin, or respiratory tract on prolonged exposure
Environment Hazards: Low environmental hazard under normal usage
Signal Word: None
Hazard Statements: None
Precautionary Statements: Avoid dust formation, maintain ventilation, wash hands after handling

Composition / Information on Ingredients

Chemical Name: L-Serine
Concentration: >98% (as pure substance)
Impurities: Trace inorganic salts, moisture (<1%)
Other Components: No hazardous additives present

First Aid Measures

Inhalation: Move to fresh air, support breathing as needed
Skin Contact: Remove contaminated clothing, wash affected area with plenty of water and soap
Eye Contact: Flush eyes with water for at least 15 minutes, seek medical attention if irritation persists
Ingestion: Rinse mouth, drink water, seek medical advice if symptoms develop
Advice for Medical Professionals: Treat symptomatically, no known specific antidote

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: High pressure water jet can scatter powder
Specific Hazards from Combustion: Carbon oxides, nitrogen oxides may form if burned
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Special Procedures: Prevent water used for extinguishing from entering drains

Accidental Release Measures

Personal Precautions: Wear protective clothing to avoid dust contact with skin, eyes, and lungs
Environmental Precautions: Prevent spillage from entering soil and waterways
Clean-Up Methods: Clean spills with shovel or scoop into suitable container for disposal, flush residues with water
Other Considerations: Avoid dust generation, maintain adequate ventilation

Handling and Storage

Handling: Use in well-ventilated areas, minimize dust formation, wear suitable gloves and eye protection
Hygiene Measures: Wash hands thoroughly after handling, do not eat or drink in work area
Storage Conditions: Store in cool, dry place away from direct sunlight and incompatible substances, keep container tightly closed
Packaging Materials: Use original container or approved alternatives, clearly labeled

Exposure Controls and Personal Protection

Control Parameters: No occupational exposure limits established
Engineering Controls: Use local exhaust or general ventilation to minimize airborne dust
Personal Protective Equipment: Wear protective gloves (nitrile or latex), safety goggles, dust mask (P2/FFP2), lab coat
Environmental Exposure Controls: Avoid discharge into the environment, follow good containment practices

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 4.0–6.0 (1% solution in water)
Melting Point: 222°C (decomposes)
Boiling Point: Not applicable
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable
Vapor Pressure: Negligible at ambient conditions
Solubility: 25 g/100 mL in water at 20°C, negligible in alcohol and most organic solvents
Partition Coefficient (n-octanol/water): -3.6 (log Pow)
Decomposition Temperature: Decomposes above 220°C
Viscosity: Not applicable
Density: Approximately 1.6 g/cm³

Stability and Reactivity

Chemical Stability: Stable under recommended conditions
Reactivity: No hazardous reactions expected under normal conditions
Possibility of Hazardous Reactions: May react with strong oxidizers or acids
Conditions to Avoid: Excess heat, moisture, open flames
Incompatible Materials: Strong acids, strong bases, strong oxidizers
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides released upon decomposition

Toxicological Information

Acute Toxicity: Oral LD50 (rat) > 5000 mg/kg, low toxicity
Skin Irritation: Not expected to cause significant irritation
Eye Irritation: May cause mild irritation on contact
Respiratory Sensitization: Not expected under normal conditions
Skin Sensitization: Not a sensitizer
Chronic Effects: No evidence for carcinogenic, mutagenic, or reproductive toxicity
Medical Conditions Aggravated: Individuals with allergies or respiratory sensitivity may react to dust exposure
Other Effects: No significant health hazards known from available data

Ecological Information

Aquatic Toxicity: Considered low; not expected to be harmful to aquatic organisms
Persistence and Degradability: Readily biodegradable, naturally occurring amino acid
Bioaccumulative Potential: Does not bioaccumulate
Mobility in Soil: High water solubility suggests mobility, but rapid degradation limits environmental risk
Additional Information: Avoid release to large quantities in water, dispose of in accordance with regulations

Disposal Considerations

Waste Disposal Methods: Collect and place in suitable containers for local disposal as non-hazardous chemical waste
Contaminated Packaging: Dispose packaging in accordance with local, regional and national regulations
Additional Notes: Do not dispose to drains or natural waters, seek advice from licensed waste contractor for bulk waste

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not classified as hazardous for transport
Transport Hazard Class: None
Packing Group: None
Marine Pollutant: No
Special Precautions: Avoid spillage during transport, keep containers secure and upright

Regulatory Information

GHS Classification: Not classified as hazardous
TSCA (US): Listed
EINECS (EU): 200-274-3
REACH Status: Exempt as naturally occurring substance
Other Regulations: Not listed as dangerous under major chemical control regulations
Label Elements: No hazard pictograms required
Restrictions: No known restrictions beyond general safety measures
Additional Standards: Food and pharmaceutical uses must comply with specific quality standards outlined by authorities (e.g., USP, FCC, EU Pharmacopoeia)